• Journal of Plant Biology
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• 제34권1호
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• pp.53-57
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• 1991

대두의 자엽을 제거한 유식물에서 polyamine과 methylglyoxal bis(guanylhydrazone)(MGBG)가 diamine oxidase의 활성에 미치는 영향을 조사하여 다음과 같은 결과를 얻었다. $10^{-2}\;M$의 putrescine, spermidine과 spermine을 처리하였을 때에는 diamine oxidase의 활성이 약 80% 억제되었으나, $10^{-6}\;M$의 putrescine을 처리하였을 때에는 효소의 활성이 증가되었다. 이는 기질 특이성이 큰 putrescine에 의해 diamine oxidase가 유도될 수 있다고 사료된다. MGBG의 농도가 증가함에 따라 putrescine 함량이 증가되었다. In vitro에서 diamine oxidase의 활성은 $10^{-3}\;M$의 MGBG에서 약 40% 억제되었다. In vivo에서 diamine oxidase의 활성은 저농도의 MGBG에서 증가되었는데, 이는 MGBG가 putrescine으로부터 spermidine 형성을 억제하여 이로 인해 축적된 putrescine이 putrescine으로부터 spermidine 형성을 억제하여 이로 인해 축적된 putrescine이 diamine oxidase를 유도하는 것으로 사료된다. 반면, 고농도의 MGBG에서는 diamine oxidase의 활성이 감소되었다. 따라서 고농도의 MGBG에 의해 putrescine의 함량이 증가하는 것은 MGBG가 putrescine을 분해하는 diamine oxidase의 활성을 억제하는데 기인하는 것으로 사료된다.

• 한국토양비료학회지
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• 제36권6호
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• pp.437-444
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• 2003

본 연구는 고등식물 세포 내 대사작용에 대한 스트론티움의 역할을 구명하고자 수행되었다. Strontium에 의한 diamine 산화효소의 활성화로 putrescine의 함량은 감소하였다. 배축에서의 diamine 산화효소의 활성은 $0.5-1.8\;mol\;putrescine\;oxidation\;mg^{-1}\;protein\;min^{-1}$이었다. 자엽에서의 putrescine 감소는 적어도 diamine 산화효소에 의한 putrescine의 산화의 결과였다. 더 나아가 strontium 1-10 mM 처리에 의해 spermidine과 spermine 의 축적이 관찰되었다. strontium이 없는 대조구에 비해 spermldine은 2-3배 증가하였다. 이러한 증가는 생체중을 기준으로 하였을 경우뿐만 아니라 RNA를 기준으로 하였을 경우에도 동일한 결과였다. 결론적으로 이러한 결과는 strontium이 diamine 산화 및 polyamine 축적과 같은 polyamine의 대사와 관련되어있음을 보여주었다.

• 한국의류산업학회지
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• 제15권2호
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• pp.302-308
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• 2013

This study is a preliminary investigation of the influence of surface characteristics of substrates on detergency of particulate soil. The surface of PET film was modified with NaOH and NaOH+ethylene diamine on different times. The surface morphology of the film was scanned by AFM and surface energies were calculated from measured contact angles between several solutions and film based on the geometric mean and a Lewis acid base method. The surface morphology of PET film treated with NaOH and NaOH+ethylene diamine became more etched, and the surface area, surface roughness and the coefficient of friction of film increased with treatment of NaOH and NaOH+ethylene diamine. The contact angle of film treated with NaOH and NaOH+ethylene diamine decreased in water and surfactant solution; in addition, the surface energy increased was largely attributed to the increased portion on the polar surface energy of film. However, the effect of the diamine addition to the NaOH treatment solution on surface characteristics of PET film was insignificant.

• Bulletin of the Korean Chemical Society
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• 제9권6호
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• pp.355-359
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• 1988

The Pfeiffer effect was examined on the systems of racemic [$Co^{II}(acac)_2$(diamine)] with d-cinchonine and l-cinchonidine as chiral environment substances in methanol, ethanol, chloroform and methanol-chloroform mixture solvents. It was found that the ${\Delta}$-enantiomer is enriched for the [$Co^{II}(acac)_2$(diamine)]-d-cinchonine system, but the Λ -enantiomer is enriched for the [$Co^{II}(acac)_2$(diamine)]-l-cinchonidine system. The complexes having no N-H protons such as [$Co^{II}(acac)_2$(bpy)] and [$Co^{II}(acac)_2$(phen)] were Pfeiffer-inactive in alcoholic solvents, where bpy = 2,2'-bipyridine and phen = 1,10-phenanthroline. This was interpreted to mean that the hydrogen bonding between N-H proton of diamine ligand and C-9 hydroxyl group of alkalid plays an important role in the chiral discrimination. And the rate of antiracemization ($k_{anti}$) by the Pfeiffer effect was also measured for the [$Co^{II}(acac)_2$(diamine)]-d-cinchonine system in alcoholic solvents. It was found that the rate of appearance of the Pfeiffer effect was enhanced as the concentration of added chloroform is increased.

• Bulletin of the Korean Chemical Society
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• 제19권10호
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• pp.1099-1105
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• 1998

A series of (diamine)isopropylidenmalonatoplatinum(Ⅱ) complexes and the oxidation products, (diamine)Pt (OOC)2C=C(CH3)2(X)2, (diamine=ethylenediamine(en), 1,2-diaminopropan(dap), N-methylethylenediamine(men); X=OH, OCOCH3, OCOCF3), have been prepared, and their interaction with guanosine-5'-monophosphate (5'-GMP) have been examined by means of 1H NMR spectroscopy. The present platinum(Ⅱ) complexes have shown to interact with 5'-GMP through N7 coordination in two concecutive steps in a similar way as with cisplatin, but no interaction between the present platinum(Ⅳ) complexes and 5'-GMP was observed. However, in the presence of ascorbic acid, the platinum(Ⅳ) complexes have been found to interact with 5'-GMP with the reaction rate depending on their reduction rate.

• 마이크로전자및패키징학회지
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• 제6권2호
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• pp.23-30
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• 1999

이성질체에 따른 폴리이미드 박막의 잔류응력 영향과 모폴로지와의 상관관계가 조사되었다. 이를 위해, Poly(phenylene biphenyltetracarboximide) (BPDA-PDA)와 poly (oxydiphenylene biphenyltetracar-boximide) (BPDA-ODA)를 여러 다른 diamine인 1, 3-phenylene diamine (1, 3-PDA), 1.4-phenylene diamine (1,4-PDA)과 3.4'-oxydiphenylene diamine (3,4'-ODA) , 4,4'-oxydiphenylene diamine (4.4'-ODA)으로부터 제조하였다. 이들 박막에 대하여, Thin Film Stress Analyzer (TFSA)를 이용하여 공정온도 (25~$400^{\circ}C$)하에서 전구체의 열적 이미드화에 따라 실시간으로 폴리이미드 박막의 잔류응력 거동을 측정하였다. 폴리이미드 박막의 잔류응력은 면 방향 배향성과 사슬 질서도가 우수한 BPDA-1,4-PDA가 7MPa로 가장 낮게 나타났으며 BPDA-1,3-PDA, BPDA-3,4'-ODA, BPDA-4,4'-ODA의 경우 40~50Mpa 범위에 있었다. 이성질체에 따른 폴리이미드 박막의 잔류응력은 모폴로지 (사슬 강직도, 질서도, 배향성) 변화 및 유리전이 거동과 관련된 사슬 운동성을 이용하여 분석되었다.

• 한국결정학회지
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• 제18권1_2호
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• pp.21-25
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• 2007

Dipyridyl 리간드 L'(N,N'-bis-(1-pyridin-4-yl-ethylidene)-naphthalene-1,5-diamine)을 함유한 $CH_2Cl_2$ 용액을 $Co(NO_3)_2{\cdot}6H_2O$을 함유한 MeOH 용액 위에 깔았을 때, 배위 고분자가 아닌, 분자성 코발트 화합물 [$CoL_2(MeOH)(NO_3)_2$] (1)이 형성되었다. 화합물 1의 X-ray 구조 분석 결과, 이 화합물은 pyridyl-amine 리간드 L(N1-(4-Imino-1-methyl-but-2-enylidene)-naphthalene-1,5-diamine)을 함유하고 있었다. 반응 중에 리간드 L'이 리간드 L로 가수분해되었다는 것을 화합물 1의 구조가 강하게 암시하고 있다.

• Archives of Pharmacal Research
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• 제21권4호
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• pp.465-469
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• 1998

The search for platinum (II)-based compounds with improved therapeutic properties was prompted to design and synthesize a new family of water-soluble, third generation cis-diaminedichloroplatinum (II) complexes linked to uracil and uridine. Six heretofore unreported uracil and uridine-platinum (II) complexes are; [N-(uracil-5-yl-methyl)ethane-1,2-di-amine]dichloroplatinum (II) (3a), [N-(uracil-6-yl-methyl)ethane-1,2-diaminel dichloroplatinum (II) (3b), t[N-($2^1$, $3^1$,$5^1$-tri-O-acetyl)uridine-5-yl-methyl] ethane-1,2-diamineldichloroplatinum (II) (6a), {[N-($2^1$,$3^1$, $5^1$-tri-O-acetyl) uridine-6-yl-methyl]ethane-1,2-diamine)dichloroplatinum (II) (6b),[N-(uridine- 5-yl-methyl)ethane-1,2-diamine]dichloroplatinum (II) (7a), [N-(uridine-6-yl- methyl)ethane-1,2-diamine]dichloroplatinum (II) (7b). These analogues were prepared from the key starting materials, 5-chloromethyluracil (1a) and 6-chloromethyluracil (1b) which were reacted with ethylenediamine to afford the respective 5-[(2-aminoethyl)aminol methyluracil (2a) and 6-[(2-aminoethyl)amino]methyluracil (2b). The cis-platin complexes 3a and 3b were obtained through the reaction of the respective 2a and 2b with potassium tetrachloroplatinate (II). The heterocyclic nucleic acid bases 1a and 1b were efficiently introduced on the .betha.-D-ribose ring via a Vorbruggen-type nucleoside coupling procedure with hexamethyldisilazane, trimethylchlorosilane and stannic chloride under anhydrous acetonitrile to yield the stereospecific .betha.-anomeric 5-chloromethyl- $2^1$,$3^1$,$5^1$-tri-O-acetyluridine (4a) and 6-chloromethyl-$2^1$,$3^1$,$5^1$-tri-O-acetyluridine (4b), respectively. The nucleosides 4a and 4b were coupled with ethylenediamine to provide the respective 5-[(amino-ethyl)aminolmethyl-$2^1$,$3^1$,$5^1$-tri-O-acetyluridine (5a) and 6-[(aminoethyl)amino] methyl-$2^1$,$3^1$,$5^1$-tri-O-acetyluridine (5b). The diamino-uridines 5a and 5b were reacted with potassium tetrachloroplatinate (II) to give the novel nucleoside complexes, 6a and 6b, respectively which were deacetylated into the free nucleosides, 7a and 7b by the treatment with CH$_{3}$ONa. The cytotoxic activities were evaluated against three cell lines (FM-3A, P-388 and J-82) and none of the synthesized compounds showed any significant activity.

• 공업화학
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• 제21권1호
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• pp.1-5
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• 2010

Cu(II)와 diamine, aminothiol 그리고 dithiol과의 착물을 합성하여, 동일한 조건 하에서 DFP 분해반응성을 평가하였다. 실험결과 Lewis basicity가 높은 유기물질일수록 DFP의 분해반응을 촉진시키는 것으로 나타났다. N donor인 diamine에 비해 전자를 더 잘 제공하는 S donor를 가진 aminothiol과 결합된 Cu(II) 착물이 DFP의 가수분해 반응에 약 3배 정도 효과적인 것으로 분석되었다. Lewis basicity가 더 높은 dithiol 리간드를 사용한 경우 Cu(II)(1,2-ethane dithiol)$(NO_3)_2$의 난용성으로 인해 heterogeneous 조건하에서 반응속도를 측정하였음에도 homogeneous 조건하에서 측정한 Cu(II) (ethylenediamine)$(NO_3)_2$ 반응보다 약 1.6배 효과적이었다. DFP 분해에 대한 제올라이트의 반응성 평가에서 NaY의 경우 DFP 가수분해 반응을 촉진시키지 못하였으며, RuNaY는 DFP분해 반응이 Cu(II)-organic complex의 반응성에 비해서는 효과가 떨어지는 것으로 관찰되었다.

• 대한화학회지
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• 제14권1호
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• pp.119-122
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• 1970

In those six kinds of diamine salt crystal of which their structures had already been determined up to date, commonly one molecule of diamine and two molecules of acid were combined; although the crystal of benzidine perchlorate, only one molecule each of benzidine and perchloric acid were combined. At the case of benzidine perchlorate, one molecule acts as the role of two molecules by coincidence of the center of symmetry point of both the lattice and molecule, and perchlorate ion is locating symmetrically between two -$NH_2$ groups of different benzidine molecule, therefore benzidine and acid could be combined together with 1:1 by mole ratio. When forming the salt with diamine and acid, the combining mole ratio would be determined in accordance with the relationship between the symmetry element that presented by the space group and the symmetry element of diamine salt melecule.