• Title/Summary/Keyword: 2차 분열

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The Advancement of Breakup and Spray Formation by the Swirl Spray Jets in the Low Speed Convective Flow (전단 유동에 의한 스월 제트의 미립화 및 분무특성 향상)

  • Jeong, Jae-Chul;Yoon, Woong-Sup
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2009.05a
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    • pp.267-274
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    • 2009
  • Breakup and spray formation of pressure-swirl liquid jets injected into a low-speed convective-flow are experimentally investigated. Effects of the cross-flows on the macroscopic and microscopic spray parameters are optically measured in terms of jet Weber number and liquid-to-gas momentum ratio. The liquid stream undergoes Rayleigh jet breakup at lower jet Weber numbers and a liquid sheet isn't formed because of the weak radial velocity in the swirl jet. At higher jet Weber numbers, the macroscopic spray parameter is a very weak function of the momentum ratio but the effect of the convection on the microscopic spray parameter is significant through the secondary breakup with increasing in the liquid-to-gas momentum ratio. The convective-flow promotes bag/plume breakup and the spray formation, and its effect is more distinct at higher momentum ratio.

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Effect of Clinical Improvement of Schizophrenic Symptoms on $^{99m}Tc$-HMPAO Brain SPECT (정신분열병 환자의 임상적 증세 호전에 따른 $^{99m}Tc$-HMPAO 뇌 SPECT 소견의 변화)

  • Shin, Chul-Jin;Koong, Sung-Soo;Chung, In-Won
    • The Korean Journal of Nuclear Medicine
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    • v.31 no.3
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    • pp.310-319
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    • 1997
  • This study investigated regional blood flow changes of frontal, temporal, and basal ganglia in eleven schizophrenic patients on DSM-IV criteria to examine the relationship between rCBF and clinical improvement of symptoms. Single-photon emission computed tomography imaging with $^{99m}Tc$-HMPAO was peformed in baseline and sixth weeks after the treatment, and concurrently psychopathology was assessed by PANSS. Antipsychotics wash-out period was more than 2 weeks, and three patient were drug naive. All patients were finally divided into two groups, the improved or not improved. We examined the difference of the amount of rCBF changes between two groups. Finally, frontal activity shows no significant difference between two groups but both groups show decreased frontal blood flow after antipsychotic treatment. However, the change of right temporal rCBF had positive correlation with the change of the total PANSS score, and the change of left temporal lobe activity was greater in the improved group than in the not improved group. Our results suggest that the temporal lobe activity has relation to the underlying schizophrenic symptoms.

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대두의 방사선 감수성에 관한 연구(예보)

  • Shin-Han Kwon;Kun-Hyuk Im;Byeo-Jeong Kim
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.2
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    • pp.46-49
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    • 1964
  • 1. 본 시험에 사용된 선량범위내에서는 기건종자에 의한 Thermal neutron이나 X-ray의 처리가 발아율에 크게 영향을 미치지 못하였는데 Fast neutorn 처리종자의 발아율은 선량의 증가에 따라 거의 직선적 저하를 보였다. 2. 선량의 증가에 따라 기형엽발생율은 증가하였으며 특히 Fast neutron에서는 동일 flux일망정 Thermal neutron 조사구에 비해 발생율은 높다. 3. 저선량에서의 기형엽출현은 유식물기에서만 봇 수 있으며 성장함에 따라 회복한다. 이는 정상세포와 이상세포간의 분열속도의 차에 기인되는 상 싶다. 4. 같은 선량에서는 Fast neutron이 Thermal neutron에 비해 그 영향력이 크다는 것이 확실하며 이는 Energy의 차에서 오는 결과이다. 5. 일반적으로 선량의 증가에 따라 성숙이 연장되는 경향이 있었으며, 반면에 아주 희귀하기는 하나 개화와 성숙이 촉진되는 고체도 발견되었다. 6. 선량의 증가에따라 다소 왜소화되기는 하나 저선량에서는 오히려 유의성은 없으나 초장이 증가하였다. 7. 생육초기와 생육종기에 있어서의 선량에 따르는 초장에 대한 영향은 그 초기에 있어서 더 현저하며 성장함에 따라 회복되는 경향을 보인다. 8. 발아와 생육에 별 지장이 없이 재배할 수 있는 선량범위는 Thermal neutron에서 $1O^13$ N/$cm^2$, Fast neutron에서 5$\times$$1O^12$N/$cm^2$ 이하이면 무난할 것이며, X-ray는 본 시험에 이용한 32 Kr 이상에서도 이용에 지장이 없을 것이다.

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Chromosomes of Arkshell, Scapharca broughtonii Schrenck (피조개의 염색체)

  • YOO Myong-Suk;LEE Jeong-Mee;KIM Il-Bong
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.25 no.3
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    • pp.171-175
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    • 1992
  • In 1991, specimens of the arkshell, Scapharca broughtonii of Arcidae(Ptriomorphia, Mollusca) were collected from bottom culture bed at Namhae Island in Korea. The chromosomes were examined in the colchicinetreated cells of trochophore larva based on the air-drying method. Diploid number of the chromosome was 38 which were classified as metacentrics(pairs 5, 8, 13), meta or submetacentrics(pairs 6, 7), submetacentrics(2, 3, 9, 10, 12, 15, 16, 17, 18, 19) and subtelocentrirs(pairs 1, 4, 11, 14). No telocentric chromosome was observed.

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Mossbauer Spectra of the $\textrm{Cd}_{x}\textrm{Ni}_{1-x}\textrm{Fe}_{2}\textrm{O}_{4}$ ($\textrm{Cd}_{x}\textrm{Ni}_{1-x}\textrm{Fe}_{2}\textrm{O}_{4}$의 Mossbauer 스펙트럼)

  • Baek, Seung-Do
    • Korean Journal of Materials Research
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    • v.7 no.7
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    • pp.618-622
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    • 1997
  • 상온에서 측정한 Cd$_{x}$Ni$_{1-x}$Fe$_{2}$O$_{4}$의 Mossbauer 스펙트럼은 조성비에 따라 x값이 0.4이하인 시료에서는 준강자성에 의한 여섯개의 공명 흡수선, x값이 0.5인 시료에서는 이완된 형태의 공명흡수선, 그리고 x값이 0.6시료인 상자성에 의한 두개의 공명 흡수선이 나타났다. Cd$_{x}$Ni$_{1-x}$Fe$_{2}$O$_{4}$의 x값이 0.4이하인 시료의 초미세 자기장(H$_{hf}$)과 x값이 0.6 이상인 시료의 사중극자 분열치 (Q.S.)는 Cd농도가 증가함에 따라 감소한다. 시료의자기적 성질에 따른 이성질체 이동치(I.S.)의 차이는 있으나, Ni와 Cd이온의 농도에 따른 뚜렷한 의존성은 나타나지 않았다.다.

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Expression of bcl-2 in Non-small Cell Lung Cancer and its Effects on Cell Proliferation and Survival (비소세포 폐암에서 bcl-2의 발현률과 세포분열주기 및 예후에 미치는 영향)

  • Kuk, Hiang;Koh, Hyeck-Jae;Gu, Ki-Seon;Jeong, Eun-Taik
    • Tuberculosis and Respiratory Diseases
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    • v.46 no.1
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    • pp.36-43
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    • 1999
  • Background : Tumor growth is the net result of intrinsic proliferation and escape from active cell death. bcl-2 is a member of a new category of oncogenes that is not involved in influencing cell proliferation but is involved in regulating cell death(apoptosis). Based on this information, it seems to be reasonable to expect that there may be clinical prognostic significance of bcl-2 expression in non-small cell lung cancer. But its prognostic significance is not established. Methods: To investigate the role of bcl-2 in lung cancer, we performed immunohistochemical stain of bcl-2 on 57 biopsy specimens from resected primary non-small cell lung cancer. Thereafter, flow cytometric cell cycle analysis was done. And we analyzed the correlation between bcl-2 expression, clinical parameters, S-, $G_1$-phase fraction and survival. Results: bcl-2 were detected in 43.8% of total 57 patients(according to histology, squamous cancer 47%, adenocarcinoma 32%, according to TNM stage, I 28.6%, II 52.3%, III 45.5%. both differences were insignificant). By using the flow cytometric analysis, mean S-phase fraction of bcl-2(+) and (-) group were 14.1($\pm7.8$)%, 24.7($\pm10.5$)% (p<0.005), mean $G_1$-phase fraction of bcl-2(+) and bcl-2(-) group were 75.5($\pm10.8$)%, 65.5($\pm11.4$)%(p<0.05). 2yr, 3yr and 5yr survival and median survival time of bcl-2(+) group were 65%, 54%, 41%, 53 months, and those of bcl-2(-) group were 71%, 52%, 46%, 37 months. (p>0.05, Kaplan-Meier, log rank) Conclusion: bcl-2 was detected in 43.8% of primary non-small cell lung cancer. The S-phase fraction of bcl-2(+) group was less than bcl-2(-) group, and G1-phase fraction of bcl-2(+) group was more than bcl-2(-) group. But, expression of bcl-2 could not be a prognostic factor.

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Karyological Study of Japanese Quail (Coturnix coturnix japonica) (일본산 메추리(Coturnix coturnix japonica)의 핵형연구)

  • ;;N. S. Fechheimerlr
    • Korean Journal of Poultry Science
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    • v.17 no.4
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    • pp.269-274
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    • 1990
  • Chromosome complements of Japanese quail (Coturnix coturnix japonica) were studied using several tissues which involving testis, leukocytes and embryos. The diploid count was estimated to be 2n=78. Analyzing the metaphase of secondary meiosis in spermatocytes, the haploid count estimated to be n=39. Morphometric analysis were studied by the centromeric index and relative length of 8 macro-chromosomes and Z, W chromosomes The differences of morphological feature were not significant among tissues. Exceptionally the chromosome 4 shelved a considerable variety in the presence of it's short arm.

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Analysis of droplet formation under sloshing phenomena in liquid fuel tank (액체 연료 탱크 내 슬로싱 현상에서의 액적 형성 분석)

  • Sungwoo Park;Jinyul Hwang
    • Journal of the Korean Society of Visualization
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    • v.21 no.2
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    • pp.102-110
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    • 2023
  • With the global shift from a carbon-based economy to a hydrogen-based economy, understanding the sloshing phenomenon and its impact on boil-off rate (BOR) in liquid hydrogen (LH2) tank trailers is crucial. Here, we analyze the primary breakup process under sloshing phenomena in a liquid fuel tank. We observe the growth of multiple holes on the sheet-like structures and the formation of ligament structures reminiscent of jet atomization. Through the extraction of three-dimensional liquid regions, we analyze the geometrical characteristics of these regions, enabling the classification of sheets, ligaments, and droplets. The present findings could contribute to understanding the breakup mechanism and hold potential for the development of strategies aimed at minimizing BOR.

Studies on Meiosis of PMC's in P. alba × glandulosa and Their Parents (P. alba × glandulosa와 그 양친(両親)의 Pollen Mother Cell의 Meiosis에 관(關)한 연구(硏究))

  • Cheung, Hyon Pae;Chon, Sang Kun;Kim, Mal Sook;Kim, Chung Suk
    • Journal of Korean Society of Forest Science
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    • v.45 no.1
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    • pp.51-61
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    • 1979
  • The chromosome behavior and it's synapsis in the meiosis of pollen mother cell were studied on Populus alba L. as a female parent tree, Populus glandulosa Uyeki as a male parent tree and their hybrid, Populus alba x glandulosa. 1. At metaphase I, the number of nuclear plates with early separation chromosome were observed with the lowest proportion of 11.0% in Populus glandulosa and with the highest proportion of 13.0% in Populus alba${\times}$glandulosa. 2. At metaphase II, early separation chromosomes appeared with the frequency of 11.0% in Populus alba${\times}$glandulosa. But the frequency was not different with those of the parental trees. 3. At anaphase I, lagging chromosomes appeared with some high rate of 11.6% in Populus alba${\times}$glandulosa and yet the number of chromosome bridges in populus alba x glandulosa almost were not different with the partental trees. 4. At anaphase II, lagging chromosomes appeared with some high frequency of 10.2% in Populus alba${\times}$glandulosa and the chromosome bridges in Populus glandulosa appeared with the highest frequency in all studied trees. 5. The frequency of abnormal pollen sporad was the highest value of 8.2% in Populus alba${\times}$glandulosa among the studied trees. With the results, it might be assured that the chromosome segregation and it's synapsis behaved normally in Populus alba, Populus glandulosa and Populus alba x glandulosa, and so all the studied trees could produced normal pollens.

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Correlation of Proliferating Cell Nuclear Antigen (PCNA) Expression and S-phase Fraction, Survival Rate in Primary Non-Small Cell Lung Cancer (원발성 비소세포 폐암에서 PCNA의 발현정도와 암세포의 분열능 및 생존률과의 관계)

  • Yang, Sei-Hoon;Kim, Hak-Ryul;Gu, Ki-Seon;Jung, Byung-Hak;Jeong, Eun-Taik
    • Tuberculosis and Respiratory Diseases
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    • v.44 no.4
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    • pp.756-765
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    • 1997
  • Background : To study the prognosis of patients with lung cancer, many investigators have reported the methods to detect cell proliferation in tissues including PCNA, thymidine autoradiography, flow cytometry and Ki-67. PCNA, also known as cyclin, is a cell related nuclear protein with 36KD intranuclear polypeptide that is maximally elevated in S phase of proliferating cells. In this study, PCNA was identified by paraffin-embedding tissue using immunohistochemistry which has an advantage of simplicity and maintenance of tissue architecture. The variation of PCNA expression is known to be related with proliferating fraction, histologic type, anatomic(TNM) stage, degree of cell differentiation, S-phase fraction and survival rate. We analyzed the correlation between PCNA expression and S-phase fraction, survival. Method : To investigate expression of PCNA in primary lung cancer, we used immunohistochemical stain to paraffin-embedded sections of 57 resected primary non-small cell lung cancer specimen and the results were analyzed according to the cell type, cell differentiation, TNM stage, S-phase fraction and survival. Results : PCNA expression was divided into five group according to degree of staging(-, +, ++, +++, ++++). Squamous cell type showed high positivity than in adenocarcinoma. Nonsignificant difference related to TNM stage was noticed. Nonsignificant difference related to degree of cell differentiation was noticed. S-phase fraction was increased with advance of PCNA positivity, but it could not reach the statistic significance. The 2 year survival rate and median survival time were -50% 13 months, +75% 41.3 months, ++73% 33.6 months, +++67% 29.0 months, ++++25% 9 months with statistic significance (P<0.05, Kaplan-Meier, generalized Wilcox). Conclusion : From this study, PCNA expression was high positive in squamous cell cancer. And, there was no relationship between PCNA positivity and TNM stage, cellular differentiation or S-phase fraction. But, the patients with high positive PCNA staining showed poor survival rate than the patients with lower positive PCNA staining (p<0.05). It was concluded that PCNA immunostaining is a simple and useful method for survival prediction in paraffin embedded tissue of non-small cell lung cancer.

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