• Title/Summary/Keyword: 2중분무

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Effects of Aerosol Colistin Treatment of Pneumonia Caused by Multi-drug Resistant Acinetobacter baumannii (다약제 내성 Acinetobacter baumannii 에 의한 폐렴에서 Colistin 분무치료의 효과)

  • Choi, Hye Sook;Hwang, Yeon Hee;Park, Myung Jae;Kang, Hong Mo
    • Tuberculosis and Respiratory Diseases
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    • v.64 no.1
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    • pp.8-14
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    • 2008
  • Background: Acinetobacter infections are difficult to treat as they often exhibit multiple resistance to the antibiotics that are currently available for the treatment of pneumonia. Colistin is active against gram-negative bacteria, including the multiple drug resistant (MDR) Acinetobacter species. However, intravenous administration of colistin was abandoned because of its nephrotoxicity and neurotoxicity. The aims of this study were to examine the efficacy and safety of colistin administered by aerosol in the treatment of pneumonia caused by MDR Acinetobacter baumannii. Methods: We retrospectively reviewed the medical records of patients admitted to the intensive care unit (ICU) from Dec. 2006 to Aug. 2007 who had been diagnosed as suffering from pneumonia due to MDR Acinetobacter baumannii and had been treated with nebulized colistin. Results: 31 patients received aerosolized colistin. The average duration of the treatment was $14{\pm}7$ days and the daily dose of ranged from 225 mg to 300 mg. All patients received concomitant intravenous antimicrobial agents. The average length of the stay in the ICU was $34{\pm}21$ days and in the hospital $58{\pm}52$ days. The overall microbiological eradication was observed in 25 patients (80.6%). 14 of these (56%) were cured, and 11 (44%) were infected with other microorganisms. The overall crude mortality of the ICU was 48%. Nephrotoxicity and significant bronchial constriction did not occur in any patient during neublized colistin treatment. Conclusion: Nebulized colistin may be a safe and effective option in the treatment of pneumonia due to MDR Acinetobacter baumannii. Its role in therapy warrants further investigation in comparative studies.

2-Dimensional Unsteady Modeling of Spray Flame Formed in a Laminar Counterflow Field - Effects of Equivalence Ratio and Fuel - (층류 대향류장에 형성된 분무화염의 2차원 비정상 모델링 -당량비 및 연료종에 관한 영향-)

  • Hwang, Seung-Min;Chung, Jin-Do;Seo, Byung-Min;Kim, Young-Woo
    • Journal of Korean Society of Environmental Engineers
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    • v.31 no.10
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    • pp.933-940
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    • 2009
  • To evaluate characteristics in spray flame, laminar counterflow is investigated on the effects of equivalence ratio and fuel by a two-dimensional DNS (direct numerical simulation). For the gaseous phase, Eulerian mass, momentum, energy, and species conservation equations are solved. For the disperse phase, all individual droplets are calculated by the Lagrangian method without the parcel model. n-Decane ($C_{10}H_{22}$) and n-heptane ($C_7H_{16}$) is used as a liquid spray fuel, and a one-step global reaction is employed for the combustion reaction model. As equivalence ratio increases, the fuel ignites early and the high temperature region spreads wider. The peak value of temperature, however, tends to once increase and then decreases with increasing equivalence ratio. The decrease in the peak value of temperature for the higher equivalence ratio condition is caused by the cooling effect associated with droplet group combustion. Since the evaporation of n-heptane is early, the high temperature region spreads wider than ndecane, but the peak values of temperature for both n-heptane and n-decane is almost same.

Preparation of Transparent and Conducting Tin Oxide Films by the Ultrasonic Spray Pyrolysis (초음파분무열분해에 의한 투명전도성 산화주석막의 제조)

  • Kim, Sang-Kil;Yoon, Cheonho
    • Applied Chemistry for Engineering
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    • v.9 no.2
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    • pp.214-219
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    • 1998
  • The transparent conducting tin oxide films were deposited on g1ass substrates by the ultrasonic spray pyrolysis. Examined were effects of deposition parameters on the electrical resistance, optical transmittance, crystal structure, and thickness of tin oxide films. As both the deposition time and concentration of tin(IV) chloride increase, the deposited tin oxide films exhibited the decrease of electrical resistance and optical transmittance in the visible and near infrared region. With increasing heat-treatment temperature in air, the deposited tin oxide films showed the enhanced electrical resistance and optical transmittance. This study suggests that the ultrasonic spray pyrolysis may be a promising deposition technique effectively to prepare transparent conducting films of good quality in a single step.

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Powder Characteristic Changes of Spray-Dried WC-17%Co Composite Powder by Heat Treatment (분무건조된 WC-17%Co 복합분말의 열처리에 따른 분말특성변화)

  • Seol, Dong-Uk;Kim, Byeong-Hui;Seo, Dong-Su
    • Korean Journal of Materials Research
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    • v.7 no.12
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    • pp.1027-1032
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    • 1997
  • 본 연구에서는 용사용WC-17%Co 복합분말을 분무건조법으로 제조하고 열처리 온도(85$0^{\circ}C$, 100$0^{\circ}C$, 115$0^{\circ}C$, 130$0^{\circ}C$)에 따른 조립분말의 미세구조, 입도분포, 유동도, 및 결정상변화를 고찰하였다. 분무건조상태의 입형은 구형이었으며, 입도분포, 평균입자크기, 유동성은 각각 20.6-51.7$\mu\textrm{m}$, 27.2$\mu\textrm{m}$, 0.26 sec/g 이었다. 열처리에 의하여 조립분말은 치밀화되어 130$0^{\circ}C$ 열처리 후에는 입도분포와 평균입자크기가 각 각 6.9-37.9$\mu\textrm{m}$과 17.8$\mu\textrm{m}$로 감소하였으며, 유동성은 0.12 sec/g로 향상되었다. 열처리중에 WC와 Co의 상화확산에 의하여 Co$_{6}$W$_{6}$C및 Co$_{3}$W$_{3}$C이 생성되었으며, 두 상이 나타나는 임계온도는 115$0^{\circ}C$이었다.

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Studies on Stability for the Quality of Ginseng Products - 1. Quality Characteristics of Freeze and Spray Dried Red Ginseng Extract Powders - (인삼제품(人蔘製品)의 품질안정성(品質安定性)에 관한 연구(硏究) - 1. 동결(凍結) 및 분무정분(噴霧精粉)의 품질특성(品質特性) -)

  • Choi, Jin-Ho;Byun, Dae-Seok;Park, Kil-Dong
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.13 no.1
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    • pp.57-63
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    • 1984
  • This study was designed to compare the quality characteristics of freeze and spray dried red ginseng extract powders(RGEPs) by drying methods, which have been required to maintain the stability for the quality. Chemical compositions, major ginsenoside contents and color intensities of these Products were compared by drying conditions. The moisture absorption rates and optical densities also were compared during storage under maltreatment conditions of a various relative humidities (75, 86and 92 RH) and two different temperatures (37 and $50^{\circ}C$). It was found that decreases of total major ginsenosides contents in freeze and spray dried RGEPs were 5.4 % to 6.7 % during storage for 6 months at $37^{\circ}C$, 75 % RH. When these products packaged with inner seal of Al-foil laminate paper (Al-foil; 9 ${\mu}m$) were stored for 6 months at $37^{\circ}C$, 75 % RH. the moisture absorption rates of freeze and spray dried RGEPs were ranged 42 % to 82 %, 8 % to 16 %, respectively. In storage for 6 months at $37^{\circ}C$, 86 % RH, spray dried RGEP was higher in brown pigment($400{\sim}490nm$) than freeze dried RGEP while freeze dried was higher in pyrazine (278 nm), HMF and furfural (285 nm) than spray dried RGEP. It was found that RGEPs showed a strong anti-oxidative activity by electron donating ability to DPPPH, but there was no significant difference between freeze and spray dried RGEPs.

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Synthesis of ceria by combination of spray pyrolysis, postheat, and ball-milling and its characterization (분무열분해, 후소성 및 볼밀링을 조합한 방법을 이용한 세리아의 합성 및 특성연구)

  • Kim, Hyun-Ik;Kim, Sang Pil;Song, Jae-Kyung;Kim, Sang Hern
    • Journal of the Korean Applied Science and Technology
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    • v.35 no.4
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    • pp.1057-1072
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    • 2018
  • In this study, micro-sized $CeO_2$ particles were synthesized by spray pyrolysis, and EG(ethylene glycol) and CA(citric acid) as organic additives were added to obtain hollow and porous particle during spray pyrolysis, and characteristics of obtained ceria were investigated according to the amount of added organic additives. Spray pyrolysis, postheat and ball-milling were combined to give 6 paths. $CeO_2$ nano-sized particle was obtained by the path which has sequence of Spray Pyrolysis with 0.5 M of EG and CA${\rightarrow}$Post-heat${\rightarrow}$Ball-milling${\rightarrow}$Post-heat among 6 paths. The average particle size(24 nm with standard deviation of 3.8 nm) of $CeO_2$ nano-sized particle by TEM analysis is close to the primary particle size(20 nm) which was calculated by Debye-Scherrer equation. To investigate the morphological characteristics and structure of the synthesized nanoparticle powders, SEM(Scanning Electron Microscopy), XRD(X-Ray Diffractometer) and TEM(Transmission Electron Microscopy) were used.

A Study on Spray Characteristics of Water Mist Nozzle with Mid-low Pressure for Fire Suppression (화재용 중저압 물분무 노즐의 분무특성에 관한 연구)

  • 김성찬;유홍선;박현태;방기영
    • Journal of the Korean Society of Safety
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    • v.18 no.1
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    • pp.28-32
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    • 2003
  • The present study investigates the spray characteristics of water mist nozzle with mid-low pressure for fire suppression. The examined nozzle types are swirl and spiral nozzle. The result shows that K factor of water mist nozzle is much smaller than those of general sprinkler. Spray angle of spiral nozzle is largest and more than $150^{\circ}$. SMD(Sauter Mean Diameter) of water mist nozzles is ranged between 100 and 200$\mu\textrm{m}$through measuring by image processing method. The spray pattern of spiral nozzle represent that water flux of first stream is 2 times larger than that of second stream. This study will contribute better understandings of the water-mist spray characteristics and useful daia for developing the water-mist nozzles.

Cosmetic Corrosion of 11 % Cr and 17 % Cr Ferritic Stainless Steels for Automotive Exhaust Systems in an Environment containing Deicing Salts (제설염 환경에서 자동차 배기계용 11% Cr, 17% Cr 페라이트 스테인리스강의 외면부식특성)

  • Beom, Won-Jin;Park, Chan-Jin;Kim, Yeong-Ho;Yu, Han-Jin
    • Proceedings of the Korean Institute of Surface Engineering Conference
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    • 2008.11a
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    • pp.31-31
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    • 2008
  • 복합 싸이클 시험 모니터링을 통해 NaCl, $CaCl_2$ 제설염 환경에서 11 % Cr, 17 % Cr 페라이트 스테인리스강의 외면부식특성을 조사하고자 하였다. 용액 내 NaCl 및 $CaCl_2$의 농도가 증가함에 따라 용액의 pH가 떨어졌으며, $CaCl_2$의 농도증가에 따른 산성화도가 NaCl에 비해 크게 나타났다. 염수분무-건조-습윤 과정의 반복으로 구성되어 있는 복합싸이클 시험 중 소재의 표면상태 변화를 모니터링 한 결과, 건조 과정 중에 공식이 시작되며, NaCl 환경의 경우엔 습윤과정 중에 $CaCl_2$ 환경의 경우엔 건조 중에 공식성장이 주로 이루어지는 것으로 확인되었다.

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Feature of Spray Transport and Atomization from Two-Phase Swirling Jet with Air-to-Liquid Mass Ratio (공기액체질량비에 따른 이류체 선회형 분사의 분무거동 및 미립화 특성)

  • Lee, Sam-Goo
    • Journal of the Korean Society of Propulsion Engineers
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    • v.8 no.2
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    • pp.39-45
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    • 2004
  • Experiments were performed in a two-phase swirling spray facility that has been described elsewhere. Measurements of spray transport and drop size distribution are analyzed over wide ranges of air to liquid mass flow ratios, utilizing four different internal mixing pneumatic nozzles. The spatial distributions of mean velocities. fluctuating velocities, and velocity-diameter correlation were quantitatively analyzed. Also, the exponential correlation curves were obtained with ALR along the spray centerline, which indicated an approximately identical formulation regardless of ALR. It indicated that the atomization characteristics were remarkably superior in the case of 30o of swirl angle with higher ALR. Among other things. nozzle configuration is one of the significant parameters affecting spray phenomena from an internal mixing nozzle. Turbulence intensities are increasingly degenerated with an increase of nozzle configuration, allowing a rapid increment of drop size distribution.

Manufacture of Nano-Sized Ni-ferrite Powder from Waste Solution by Spray Pyrolysis Process (분무열분해 공정에 의한 폐액으로부터 니켈 페라이트 나노 분말 제조)

  • Yu Jae-Keun;Suh Sang-Kee;Kang Seong-Gu;Kim Jwa-Yeon;Park Si-Hyun;Park Yaung-Soo;Choi Jae-Ha;Sohn Jin-Gun
    • Resources Recycling
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    • v.12 no.4
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    • pp.20-29
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    • 2003
  • In order to efficiently recycle the waste solution resulting from shadow mask processing, nano-sized Ni-ferrite powder was fab-ricated through spray pyrolysis process. The average particle size of the powder was below 100nm. In this study, the effects of the reaction temperature. the concentration of raw material solution and the injection speed of solution on the properties of powder were respectively investigated. As the reaction temperature increased from $800^{\circ}C$ to $1100^{\circ}C$, average particle size of the powder significantly Increased and power structure became more solid, whereat its specific surface area was greatly reduced. Formation rate and crystallization of($NiFe_2$$O_4$) phale increased along with the temperature rise. As the concentrations of iron and nickel components in wastere solution increased, particle size of the powder became larger, particle size distribution became more irregular, and specific surface area was reduced. Formation rate and crystallization of $NiFe_2$$O_4$ phase increased significantly along with the increase of the concentration of solution. As the inlet speed of solution increased, particle size of the powder became larger, particle size distribution became wider, specific surface area was reduced and powder structure became less solid. As the inlet speed of solution decreased, formation rate and crystallization of $NiFe_2$$O_4$ phase significantly increased.