• 제목/요약/키워드: 1st-order system

검색결과 421건 처리시간 0.024초

자궁적출술 환자를 위한 critical pathway 개발과 적용효과 (Critical Pathway Development for the Hysterectomy Patients and its applied Effect)

  • 노기옥;박경숙
    • 여성건강간호학회지
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    • 제6권2호
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    • pp.234-257
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    • 2000
  • At present in the medical care, the study and effort for producing health service to consider efficiency, effectiveness, and quality are urgently called for because of the difficulty in the keen competition according to the inter- nationalization and opening, the operation in the medical institution service testing system, the change in the medical policy of KDRGs, and the lack of the health care cost increasing rate. As an alternative, the case management for the new management system is introduced in the U.S., and the Critical Pathway that is the method designing the contents of activity and its result has been developed and applied in order to anticipate and manage the patient-outcome for the realization of the cost-effective case-management. Thus, this study intended to analyze the effectiveness to obtain by developing the Critical Pathway presented as the method to improve the quality-betterment and cost effectiveness through the continuous and consistent patient management for the hysterectomy patient and applying it to the real practice. As a study method, this author formed a conceptual framework through considering five Critical Pathway used in the current U.S. and three Critical Pathway presented in the literature to develop the Critical Pathway for the hysterectomy patient, and made out the preliminary Critical Pathway through reviewing the old chart. This author made the verified the validity of the expert group about the developed Critical Pathway, and to confirm the possibility of practice application, completed and settled the final Critical Pathway after using the Critical Pathway to the hysterectomy patient from March 1st to 15th, 1997. Finally, to analyze the application-effect of the developed Critical Pathway, this author offered health care service applying the Critical Pathway to the hysterectomy patient from April 15th to August 31th, 1997. The guide for the Critical Pathway was carried out in advance by outpatient setting nurse for outpatient setting visit before the operation, and after hospitalization the primary nurse monitored the execution degree on the every duty. After discharge this author surveyed the complication through phone visiting, and one month after discharge surveyed the patient's reaction about the offered service when outpatient setting visit and analyzed the result. The source for health care cost was obtained by the statistics about the hospital charge which was offered by the General Business Department. The results were as follows. 1. It was decided that the vertical line of the Critical Pathway was made up of eight items such as monitoring/assessment, treatment, line/drains, activity, medication, lab test, diet, patient teaching, and the horizontal line of the Critical Pathway was made up of from hospitalization to discharge. 2. After the analysis of service contents through reviewing the old chart, it was decided that the horizontal line of the preliminary Critical Pathway was made up of from hopitalization to fourth postoperative day, and the vertical line of it was divided into eight items which were the contents to occur with the time frame of the horizontal line. 3. After the verifying the validity of the expert group about the preliminary Critical Pathway, the horizontal line was amended from hopitalization to third postoperative day, and taking their consensus, some contents of the horizontal line was amended and deleted. 4. From March 1st to 15th, 1997, to confirm the clinical suitability, this author offered eight hysterectomy patients the medical service through the Critical Pathway. The result was that three of them could be discharged at the expected discharge day, and the others later than that day. Supplementing the preliminary Critical Pathway through analyzing the cause of that delay- case, this author developed the final Critical Pathway. 5. There were no significant differences between the experimental and the control group in the incidence of complication(P > 0.05). 6. The 92.4% of experimental group was satisfied with the Critical Pathway service. 7. The length of hospital stay of the experimental group offered with the Critical Pathway service was 4.6 days and there was a significant difference that it was 1.3 days shorter than that of the control group(t=-29.514, P=0.000). 8. There wsa a significant difference that the mean medical charge per one patient of the experimental group offered the Critical Pathway service was cheaper \124,150 than that of the control group(t=-9.826, P=0.000). 9. The result that the author assumed and analyzed hospital income with the rate of turning bed was assumed that the increase of hospital income was \63,245,072 for that study, and the income increase was expected with \68,704,864 for a year. The result that this author applied the Critical Pathway to the hysterectomy patient have no differences in the incidence of complication, high satisfaction with that service, and the length of hospital stay decreased in the experimental group, and the mean hospital charge per one patient decreased, but hospital income increased. Suggestions for further study and nursing practice are as follows. 1. The study to apply the Critical Pathway for a year, verify the validity, and measure the effect repeatedly is needed. 2. To apply and manage the Critical Pathway effectively, the study to computerize it is needed. 3. The study to develop hospital-based Critical Pathway about other diseases or procedure, and measure the effect is needed.

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일부(一部) 농촌지역(農村地域) 주부(主婦)의 보건의료(保健醫療)에 대한 지식(知識).태도(態度) 및 실천도(實踐度)에 관한 조사(調査) -마을보건임원조직(保健任員組織) 활용지역(活用地域) 중심(中心)- (A Study on Knowledge, Attitudes, and Practice of Health Care of Housewives in Rural Area (with Established Viliage Voluntary Health Worker System))

  • 정혜경;최삼섭
    • Journal of Preventive Medicine and Public Health
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    • 제12권1호
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    • pp.107-120
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    • 1979
  • In order to determine the knowledge of, attitudes to, and practice of housewives toward health care in a rural area, a survey with questionnaire was carried out with 87 housewives who were sampled randomly from 6 villages in Sudong Myun, from April 16th to 21st, 1979. The following results were obtained. 1. Of the housewives studied, 61.5% knew that B.C.G. is a vaccine for T.B prevention and 12.3% knew that D.P.T. is a vaccine for diphtheria, pertussis, and tetanus. 2. The vaccination rate of the children under six-year of the housewives studied was: polio 83.1%, B.C.G. 75.4%, D.P.T. 66.2%, and measles 55.4% respectively. 3. The vaccination rate was higher in children in the area near from the health subcenter than in there of the area further away. 4. Out of 87 respondants, 87.5% knew one or more methods of contraception for spacing children. These were: loop 69.0%, oral pill 66.7% and condom 14.9% respectively. 5. Out of 87 respondants, 82.2% knew the methods of contraception for sterilization. These were: laparascopy 87.5% and vasectomy 16.9%. 6. Out of 87 respondants those who had experience using contraceptive methods were 70.1% and present users were 47.1%. 7. Contraception practice rate was higher in the group of housewives having middle school education or above than those having primary school education or less. 8. Functions of the health subcenter listed by respondants were: patients care 72.4%, family planning 31.0%, vaccination 23.0%, T.B. control 3.4%, health education 3.4%, infant birth delivery assistance 1.1% respectively. 9. Housewives who knew that there is a village health voluntary worker in their own village were 63.2%(55), and 58.2% of those who knew appreciated her activities. 10. Purposes of expenditure of Myun community health development funds listed by respondants were: aid for patient care 34.5%, aid for health subcenter operation 16.1%, and aid for Myun health development 6.9% respectively. 11. It seems that both of the distance from the health subcenter and the utility rate level of the village health voluntary worker are co-related to the B.C.G. vaccination rate of children. 12. It seems that both of the distance from the health subcenter and the utility rate level of the village health voluntary worker are not co-related to the rate of contraception practice.

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UFID를 이용한 기본지리정보 갱신 및 지형변화율 산출 방안 연구 (A Study on Method of Framework Data Update and Computing Land Change Ratio using UFID)

  • 김주한;김병국
    • 대한토목학회논문집
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    • 제26권1D호
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    • pp.157-167
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    • 2006
  • 정부에서 추진한 1 2차 국가지리정보체계(NGIS)사업 중 1차 NGIS사업(1995~2000)은 지리정보의 구축에 편중되었고, 2차 NGIS사업(2001~2005)은 1차 사업의 결과물로 얻어진 지리정보의 유통 활용 방안에 초점이 맞추어져 있다고 할 수 있다. 현재 2차 NGIS사업의 후반기에서 1 2차 NGIS사업을 뒤돌아보면 지리정보의 갱신이라는 문제를 간과할 수 없다. 정확한 지리정보의 구축 유통 활용은 국가지리정보를 대표하는 핵심적 요소라 할 수 있듯이 지리정보의 신속한 갱신 또한 LBS(Location Based Services), Ubiquitous, Telematics와 같은 차세대 산업에 지리정보의 변경 사항을 신속 정확히 제공함으로서 2차적인 산업을 진행하도록 하는 중요한 사항이라 할 수 있다. 국토지리정보원은 1차 NGIS사업 결과 구축된 수치지도를 개선하기 위해 많은 연구를 진행하였으며, 무결점 수치지도 제작을 거쳐, NGI, NDA, NRL 3가지 파일형식으로 제공되는 기본지리정보(Framework Data)를 구축하게 되었다. 기본지리정보는 다른 지리정보에 공통적으로 포함되어 있거나, 여러 지리정보를 통합하기 위해 위치적 혹은 내용적 참조체계를 제공하는 지리정보이다. 기본지리정보는 데이터 셋, 유일식별자, 데이터 모델을 구성요소로 하고 국가적 기반자료로서의 역할을 수행하게 된다. 본 논문은 기본지리정보의 핵심 구성요소인 지형지물 유일식별자(UFID, Unique Feature Identifier)의 업무를 이용하여, 지형지물 관리기관의 현업에서 관리되는 지형지물의 생성 변경 소멸에 관한 정보를 지리정보에 실시간으로 반영하여 실용적인 기본지리정보로 갱신하는 방안에 대하여 제안하였고, 추가적으로 지형변화율을 산출하여 기본지리정보의 갱신 계획 수립에 중요한 자료를 제공하는 방안도 제안하였다.

119지역대의 공간적 배치 현황의 적절성 -Y시 H면 지역을 중심으로- (The propriety of Spatial Arrangement Condition of 119 Emergency Medical Service - Mainly Around H Town Area, Countrysid of Y city -)

  • 윤종근;최규철
    • 한국산학기술학회논문지
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    • 제18권11호
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    • pp.374-380
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    • 2017
  • 본 연구는 시골지역에 위치한 119지구대의 현황을 분석하고 이를 바탕으로 좀 더 효율적인 응급의료서비스를 이용할 수 있도록 공간적 배치의 기초자료를 제공하기 위해 Y시 H면에 소재한 119지구대를 중심으로 2016년1월 1일부터 2016년 12월 31일까지의 119지역대 환자이송 현황을 조사하였다. 수집된 자료는 SPSS 21.0을 이용하여 분석하였으며, 빈도분석을 실시하고, 가상적인 119지구대 배치 후 이송시간 및 거리는 GIS(Geographic Information System)를 이용하여 정보를 분석하였다. 연구결과, 119지구대를 이용율은 대부분 65세가 넘은 고령환자가 전체 이용환자의 57%인 수준이었으며, 실제 출동반응 현황은 현장도착 평균 거리는 6.41km(11.86분)이었으며, 현장에서 의료기관까지 소요되는 거리는 18.24km(21.52분)었다. 현재 위치하고 있는 119지역대를 중심으로 GIS를 이용하여 분석한 결과 장*리 마을로 9.12km(12분)이 소요되었으며, 환자발생지역까지 출동 후 다시 의료기관까지 가는 거리는 36.83km(62분)이 소요되는 것으로 나타났다. 장*리로 가상지구대를 설정한 경우 의료기관까지이 거리는 27.71km(50분)정도 소요되는 것으로 나타났다. 따라서 본 연구의 결과를 분석에 의하면 현재 소재하고 있는 119지역대의 위치는 환자발생지점에서 의료기관까지의 거리를 감안해 볼 때 적절하지 않은 것으로 나타났다. 이에 좀 더 많은 지역의 지구대를 중심으로 활발한 연구를 통하여 환자발생시 119지구대가 출동 시 최단의 거리와 환자 발생 지점에서 의료기관까지의 최단 거리등을 고려하여 현재 설치되어 있는 119지구대의 위치를 재고해야 될 것이다.

자동차 시트 표피재의 감성평가 (Comforts Evaluation of Car Seat Clothing)

  • 김주용;이채정;김안나;이창환
    • 감성과학
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    • 제12권1호
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    • pp.77-86
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    • 2009
  • 자동차는 첨단공업 기술이 고도로 집적되어 있는 인간-기계 시스템(man machine system)이다. 자동차에 대한 새로운 감성요구를 실현하기 위해서는 인체와 오랜 시간 접촉해 있는 시트 표피재의 분석이 반드시 필요하다. 본 연구에서는 자동차 시트 표피재의 역학적 특성과 감성을 고려한 고급감을 예측하여 고감성 내장 표피재 개발에 기여하고자 한다. 감성용어는 Softness(유연한), Elasticity(탱글탱글한), Volume(풍성한), Stickiness (끈끈한)를 설정하였으며, 이와 대응하는 표피재의 역학적 특성 치를 측정하였다. 피혁의 특성평가에 의한 결과로 resilience, bending moment, thickness와 friction 값을 얻을 수 있었으며, 이러한 역학적 특성 치를 softness, elasticity, volume, stickiness 값으로 변화하기 위해 fuzzy logic을 사용하였다. 또한 Fuzzy logic의 결과인 Softness, Elasticity, Volume, Stickiness 값으로 피혁의 고급감을 예측하기 위한 신경망 모델(Neural network)을 구성하였다. 즉, 자동차 표피재 중 피혁의 4가지 물리량으로 인간의 감성인 표피재의 고급감을 예측하여 고감성 자동차 시트 표피재의 개발을 위한 예측 모델의 가능성을 평가하였다.

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음주운전자 275명 혈액 중 마약류 및 남용약물의 분석 (Distribution of Abused Drugs in 275 Alcohol-positive Blood Samples of Korean Driver)

  • 최혜영;이주선;최상길;김은미;김재균;김영운;임미애;정희선
    • 약학회지
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    • 제52권2호
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    • pp.137-146
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    • 2008
  • Even though driving under the influence of drug (DUID) is a worldwide problem, we, Korea has no regulation system yet except for alcohol, and there are little cases reported related to DUID. In order to investigate the type of abused drugs for drivers in Korea, we tried to analyze controlled and non-controlled drugs in alcohol-positive blood samples. 275 whole bloods, which were positive for alcohol on the roadside test, were collected from the police for two months ($Nov.{\sim}Dec.$ 2006). The analytical strategy was constituted of three steps: First, alcohol in blood samples were confirmed and quantified by gas chromatography. Second, controlled drugs were screened by $Evidence_{investigator}\;^{TM}$ (Randox, U.K.) as preliminary test. It was based on immunoassay by biochip array analyzer. Nine groups of drug abuse were screened: amphetamines, methamphetamines, cannabis, cocaine, opiates, barbiturates, methadone, benzodiazepines I (oxazepam) & II (lorazepam). Finally, confirmation of these drugs was performed by GC-MS. Blood samples were extracted by solid-phase extraction by $RapidTrace^{TM}$ (Zymark, U.S.A.). After trimethylsilyl (TMS) derivatization, eluates were analyzed to GC-MS. Total 49 drugs were investigated in this study including controlled drugs, antidepressants, 1st generation antihistamines, dextromethorphan, nalbuphine, ketamine, etc. For rapid detection, we developed the automated identification system. It was made up a new software, "DrugMan", modified Chemstation data analysis menu and newly developed macro modules. A series of peak selection, identification and reporting of the results were performed automatically by this system. Concentrations of alcohol in 275 blood samples were ranged from 0.011 to 0.249% (average, 0.119%). Among 149 blood samples, just six samples (4.0%) were showed positive results to the immunoassay: one methamphetamine and five benzodiazepines group I. By GC-MS confirmation, only benzodiazepines were detected and methamphetamine was not detected from immunoassay positive blood sample. Besides these drugs, 5 chlorpheniramines, dextromethorphan, diazepam, doxylamine, ibuprofen, lidocaine and topiramate were also detected in whole bloods by GC-MS. Conclusively, the frequency of drug abuse for Korean drivers was relatively low. There was none case which illegal drug was detected. However these results were limited to alcohol positive blood samples, so it is necessary to analyze more samples including alcohol negative blood.

중소기업육성을 위한 지역균형발전 모형 연구 (A study on the model of regional balanced development for promoting small and medium sized enterprise)

  • 장석주;박노국;윤병섭
    • 벤처창업연구
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    • 제2권1호
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    • pp.133-151
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    • 2007
  • 지난 20세기 우리나라는 단시간 내에 산업화를 이룩하여 세계 12위의 주요 경제국으로 올라섰으나, 압축 성장은 사회의 모든 부문에 심각한 불균형을 초래했으며, 특히 수도권과 경부선축 중심의 발전전략은 지역경제 간의 불균형발전, 수도권 과밀화로 인한 각종 사회 경제적 문제를 노정시키고 있다. 국민의 정부 이후 행정수도 이전, 공공기관 및 연구기관의 지방이전 정책 등을 추진하고, 지역특화산업의 도출을 통한 중소기업의 육성 및 장려, 지역 균형발전을 도모하고자 하나, 중앙정부와 지방자치단체, 각종 이해집단의 이견으로 통합적이고 조화로운 지역균형발전에 대한 해법을 제시하지 못하고 있는 실정이다. 이에 본 연구는 정부의 지역 간, 산업체간 균형발전이라는 국정목표를 수행함에 있어 우리나라 지역산업 발전의 근간을 이루고 있는 중소기업의 자생적, 창의적 발전을 위한 지역균형발전 모형을 제시함으로써, 조화롭고 통합된 국가산업정책을 도모하고, 나아가 동북아 중심국가 실현의 기초를 제공하고자 한다. 그간 우리나라의 지역 중소기업정책은 수도권에 대한 입지규제와 지방에서의 하드 인프라스트럭처 구축을 중심으로 중앙정부의 하향식 정책 집행에 의해 추진되어 왔다. 정책의 유기적 연계성이 결여된 상태에서 부처별로 예산집행이 이루어짐으로써, 지역의 입지여건에 적합한 산업군집의 형성을 통한 지역경쟁력의 강화가 효율적으로 이루어지지 못한 것이 주지의 사실로, 본 연구는 지식기반경제 하에서의 지역 중소기업정책의 의미와 지역균형발전 모형의 구축 방안, 그리고 이에 근거한 지역의 중소기업발전 방안을 제시하였다.

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AHP와 IPA를 활용한 비대면 강의 속성의 중요도와 실행만족도 분석 연구 : 교수자, 학습자 비교분석을 중심으로 (A Study on the Importance of Non-face-to-face Lecture Properties and Performance Satisfaction Analysis AHP and IPA: Focusing on Comparative Analysis of Professors and Students)

  • 김민경;이태원;김선영
    • 산업경영시스템학회지
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    • 제44권3호
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    • pp.176-191
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    • 2021
  • Non-face-to-face lectures have become a necessity rather than an option since COVID-19, and in order to improve the quality of university education, it is necessary to explore the properties of non-face-to-face lectures and make active efforts to improve them. This study, focusing on this, aims to provide basic data necessary for decision-making for non-face-to-face lecture design by analyzing the relative importance and execution satisfaction of non-face-to-face lecture attributes for professors and students. Based on previous research, a questionnaire was constructed by deriving 4 factors from 1st layer and 17 from 2nd layer attributes of non-face-to-face lectures. A total of 180 valid samples were used for analysis, including 60 professors and 120 students. The importance of the non-face-to-face lecture properties was calculated by obtaining the weights for each stratified element through AHP(Analytic Hierachy Process) analysis, and performance satisfaction was calculated through statistical analysis based on the Likert 5-point scale. As a result of the AHP analysis, both the professor group and the student group had the same priority for the first tier factors, but there was a difference in the priorities between the second tier factors, so it seems necessary to discuss this. As a result of the IPA(Importance Performance Analysis) analysis, the professor group selected the level of interaction as an area to focus on, and it was confirmed that research and investment in teaching methods for smooth interaction are necessary. The student group was able to confirm that it is urgent to improve and invest in the current situation so that the system can be operated stably by selecting the system stability. This study uses AHP analysis for professors and students groups to derive relative importance and priority, and calculates the IPA matrix using IPA analysis to establish the basis for decision-making on future face-to-face and non-face-to-face lecture design and revision. It is meaningful that it was presented.

조기퇴원 수술환자의 병원중심 가정간호 효과 및 비용분석에 관한 연구 (A Study on Effectiveness of the Hospital-based Home Nursing Care of the Early Discharged Surgical Patients and its Cost Analysis)

  • 박경숙;정연강
    • 대한간호학회지
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    • 제24권4호
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    • pp.545-556
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    • 1994
  • Medical insurance and health care delivery system enabled Korean people to get the necessary medical service, but it caused increased needs for medical service, and resulted in the occurence of some problems such as a lack of manpower and medical facilities. In order to solve these problems, many countries, which already had medical insurance system had developed home care system and it has been regarded effective both in reducing costs and in increasing the rates of turnover of bed. Recently, Korea has included home nursing care in its health care delivery system, and some models of the hospital based home nursing care had been tried and its effects had been evaluated. So, author tried to run a home nursing care for the Cesarean section mothers and evaluate Its effects both in the mother's health and costs. This study was designed as a Quasi-experimental study. Subjects were thirty mothers who got Cesarean section operation in hospital in Seoul. Experimental group consisted of 15 volunteers, and control group were selected by means of matching technique. Data were gathered from February 1st to March 26th by two assistants who were trained by author. Experimental group were discharged on the 4th day after their operation, and got nursing care and assessment about their home three times on the 5th, 6th, and 7th day. Control group stayed in the hospital until 7th day as usual and were checked on the same day as above mentioned To evaluate the state of physiological recovery, vital signs, H.O.F, presence of edema in the legs, bathing, appetite, sleep, presence of pain or discomfort in the breasts, amount of lochia, color of lochia, defecation urination. To compare incidence of complication in experimental group with that in control group, specific assessment was done such variables as smell of lochia, presence of inflammation of operation wound, dizziness, and presence of immobilization in the extremities. The activities of daily living were checked Satisfaction of nursing were checked To calculate costs, author asked subjects to specify expenditure including hospital charge, traffic enpenses, and food expenses. The results were as fellows. 1. On effectiveness of home nursing careThere were n significant differences between experimental and control group in incidence of abnormal symptoms and any complication. The number of taking a bath [POD #5 P=0.001, #6 P=0.0003, #7 P=0.001] and the degree of appetite [POD #5 P=0.03, #6 P=0.02, #7 P=0.013] were significantly higher in experimental group than in control group. Contrary to author's expectation, the degree of the activities of daily living in experimental group was not higher than that of control group. All of the experimental group said they were satisfied with the home nursing care. 2. Cost analysis 1) Hospital charge of experimental group was lower than that of control group. [P=0.009] By taking home nursing care, average period of hospitalization was shortened to 3.1 days, and family members could save 22.8 hours. Total amount of money saved by early discharge was 3,443,093 Won. It is estimated that total amount of money saved by early discharge in a year will be 40,398,956 Won. 2) Home nursing care charge of 15 mothers was 1,781,633 Won. It is estimated that total amount of money Saved by it in a year Will be 20,904,493 Won. It was lower altogether than hospital charge of the three days which is 5th, 6th, 7th day of operation. The average cost of single home visit was calculated 10,940 Won. It took 87 minutes per round and it costed 1,017.3 Won. The average hour of home care was 39.0 minutes. 3) It is expected that early discharge can bring forth the increase of hospital income. On the condition that the rate of running bed is 100%, the expected increase of hospital income will be 202,374, 026 Won in a year. Suggestions for further study and nursing practice are as follows : 1. For the welfare of patients and the increased rates of running bed, home nursing care system should be included in the hospital nursing care system. 2. Studies to test effect of home nursing care on the patients with other diseases are needed. 3. Establishment of law on the practice of home nursing care is strongly recommended.

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Effect of Serum and Serum Free Media on the Developmental Competence of OPU Derived Bovine IVP Embryo

  • Choi, Byung-Hyun;Park, Bun-Young;Kong, Rami;Son, Mi-Ju;Park, Chan-Sang;Shin, Nyeon-Hak;Cheon, Hye-Young;Yang, Yeong-Rok;Lee, Jin-Woo;Jin, Jong-In;Kong, Il-Keun
    • 한국동물생명공학회지
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    • 제34권4호
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    • pp.305-310
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    • 2019
  • Embryos produced with serum show the alterations in their ultrastructure, impaired compaction, abnormal blastulation, aberrant mRNA expression profiles and large calf syndrome with greater incidences of stillbirths and deaths after birth. The aim of the present study was to describe in vitro embryo production by analyzing embryo production, fetal production and pregnancy rate in free-serum medium. The OPU-IVP data used in this study from 2016. Approximately, sixteen cows (Hanwoo), which belonged to the Institute of Gyeongsang National University, were used. Two experimental group is used in this study. Serum groups were conducted in March to July and free-serum group was conducted in September to December. The recovered cumulus-oocyte complexes were morphologically classified to four grades based on the compaction of cumulus cells layers and homogeneity of the cytoplasm. The number of oocyte was significantly greater in serum groups than that in free-serum groups (29.61 ± 0.63 vs. 15.6 ± 0.62; p < 0.05). Between serum and free-serum groups indicate that average of 1st and 2nd grade oocytes were no difference (2.38 ± 1.67 vs. 2.38 ± 1.48; p > 0.05), but number of 3rd and 4th grade oocytes were greater in serum groups than that in free-serum groups (7.31 ± 7.64 vs. 5.60 ± 6.29; p < 0.05). Embryo cleaved competence was higher in rate in free-serum groups than that in serum groups (62.1% vs. 58.3; p < 0.05). However, blastocyst developmental rate was no difference between serum and free-serum groups (33.1% vs. 43.5%; p < 0.05). 986 recipients were used for embryo transfer. Pregnancy rate was indicated that between serum and free-serum group was no difference (54.6% vs. 56.3%; p < 0.05). In conclusion, we developed the free-serum system for production of in vitro bovine embryos in order to meet the developmental and qualitative requirements for large scale commercial use.