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Progression of Atherosclerosis After Angioplasty (혈관 성형술후 동맥경화의 재발생)

  • Kwon, Hyuck-Moon;Lee, Byoung-Kwon;Suh, Sang-Ho;Roh, Hyung-Woon;Kim, Gye-Young;Lee, Na-Young
    • 순환기질환의공학회:학술대회논문집
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    • 2005.12a
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    • pp.25-26
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    • 2005
  • 동맥경화의 재발생 위치는 속도와 전단응력 등과 같은 혈류역학의 인자들의 영향을 많이 받는 혈관형태를 가진 영역이다. 이러한 결과는 관상동맥에 동맥경화의 발생빈도를 조사한 결과와 일치하고 있으며, 즉 좌전 하행지, 회선지, 및 우관동맥 등의 동맥경화성 병변 발생빈도에서 좌전하행지가 가장 많은 빈도를 나타낸다. 따라서 동맥경화의 발생 및 재형성은 혈관의 동맥경화성 위험지역의 형태적 특징, 즉, 분지부의 위치, 길이, 각도의 변화 등에 따라 달라질 수 있음을 시사한다. 동일한 관상동맥이더라도 동맥경화의 발생이 용이한 형태가 있는데, 혈관의 형태학적 특성에 따란 혈류역학적 특성이 달라지고 동맥경화가 발생할 수 있는 가능성이나 진행과정이 차이가 날 수 있음을 말한다. 특히 임계치를 넘는 고전단응력은 혈관내피세포를 파괴하거나 손상을 주며, 반대로 임계치 미만의 저전단응력은 혈류의 정체시간을 길게 하여 양쪽 모두 동맥경화성 생물학적 반응을 유발 할 수 있며, 고전단응력과 저전단응력의 빈번한 맥동성 변화작용으로 혈관이 손상될 수 있는 한계범위를 넘어서게 될 때 내피세포의 방어체계를 파괴시키거나 혈관성형술후의 신내포세포 형성과정에서 생물학적 활성반응을 촉진하게 되는 환경을 제공하게 되어 동맥경화를 촉진한다고 할 수 있다. 즉 임계치 이상의 고전단응력이 나타나는 형태와 입구경계조건이 발생되면 내피세포 손상에 따른 혈전 현상의 발생가능성이 높아지며, 임계치 미만의 저전단응력이 발생되면 동맥경화성 죽상반 재형성에 영향을 미치게 한다. 결론적으로 동맥경화의 재발생의 기전은 변형된 혈관의 형태학적인 차이와 위치에 따라 서로 다른 혈류역학적 유발할 수 있는 물리적 환경을 제공하는 데에서 출발한다고 할 수 있다.$8.0{\sim}8.3$으로 알카리 쪽으로 이동하였다. 파일롯트 규모로 본 고정화 효소 충전탑(내경 30cm, 높이 85cm)에 의한 이성화당의 생산을 시도하였던바, 고정화 효소(350 IXIU/ml-R) 1리터가 30일동안에 약 293리터의 이성화당을 생산할 수 있는 것으로 나타났다.l plane에서 선수군(選手群)이 $62.7{\pm}7.36^{\circ}$로서 비선수군(非選手群)과 별(別) 차이(差異)가 없었고, horizontalplane에서는 선수군(選手群)이 $-23.5{\pm}7.2^{\circ}$로서 비선수군(非選手群)의 $-38.8{\pm}8.2^{\circ}$에 비(比)해 유의(有意)하게 높았으며 운동후(運動後) 양군(兩群) 모두 유의(有意)하게 높았다. QRS vector 길이에서 Frontal plane에서 선수군(選手群)이 $13.86{\pm}1.44\;mm$로서 비선수군(非選手群)의 $9.62{\pm}0.97\;mm$에 비(比)해 유의(有意)하게 높았으며 운동후(運動後)에도 유의(有意)하게 높았다. Horizontal plane에서도 선수군(選手群)이 $19.82{\pm}2.10\;mm$로서 비선수군(非選手群)의 $16.90{\pm}1.39\;mm$에 비(比)해 유의(有意)하게 높았고 운동후(運動後)에도 선수군(選手群)이 유의(有意)하게 높았다. 이상(以上)을 종합(綜合)해 보면 선수군(選手群)의 R파고(波高)가 비선수군(非選手群)에 비(比)해 운동후(運動後) 계속(繼續) 유의(有意)하게 높았고, $Rv_5$

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Finite Element Stress Analysis of Bone Tissue According to the Implant Connection Type (2종의 임플란트 내부결합구조체에 따른 치조골상 유한요소응력 분석)

  • Byun, Ook;Jung, Da-Un;Han, In-Hae;Kim, Seong-Ryang;Lee, Chang-Hee
    • Journal of Dental Rehabilitation and Applied Science
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    • v.29 no.3
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    • pp.259-271
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    • 2013
  • The purpose of this study was to make the stress distribution produced by simulated different load under two types of internal connection implant system (stepped and tapered type) by means of 3D finite element analysis, The finite element model was designed with the parallel placement of the one fixtures ($4.0mm{\times}11.5mm$) with reverse buttress thread on the mandibular 1st molar. Two models were loaded with 200 N magnitude in the vertical direction on the central position of the crown, the 1.5 mm and 3 mm buccal offset point from the central position of the fixture. The oblique load was applied at the angle of $30^{\circ}$ on the crown surface. Von Mises stress value was recorded and compared in the fixture-bone interface in the bucco-lingual dimension. The results were as follows; 1. The loading conditions of two internal connection implant systems (stepped and tapered type) were the main factor affecting the equivalent bone strain, followed by the type of internal connections. 2. The stepped model had more mechanical stability with the reduced max. stress compared to $11^{\circ}$ tapered models under the distributed oblique loading. 3. The more the contact of implant-abutment interface to the inner wall of implant fixture, the less stress concentration was reduced.

Photoelastic Stress Analysis of Single Implant Restoration According to Implant Fixture Size and Abutment Diameter (단일치 임플란트에서 고정체와 지대주 직경의 차이에 따른 광탄성 응력 분석)

  • Lee, Jin-Han;Cho, Hye-Won
    • Journal of Dental Rehabilitation and Applied Science
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    • v.24 no.3
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    • pp.253-267
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    • 2008
  • The purpose of this study was to evaluate the pattern and the magnitude of stress distribution in the supporting tissues surrounding implant fixture with different diameter of implant fixtures(3i implant, Ø4.0, Ø5.0, Ø6.0mm and UCLA abutments(Ø4.1, Ø5.0, Ø6.0mm using photoelastic stress analysis. Photoelastic model was made with PL-2 resin(Measurements Group, Raleigh, USA) and three implants of each diameter were placed in the mandibular posterior edentulous area distal to the canine. Individual crowns were fabricated using UCLA abutments. Photoelastic stress analysis was carried out to measure the fringe order around the implant supporting structure under simulated loading conditions(15 lb, 30 lb). The results were as follows; 1. The more the diameter of implant fixture was increased, the less the stress concentration on cervical area of fixture was observed under loading. 2. Increasing mesiodistal diameter of implant superstructure had no much influence on stress distribution around implant fixture. 3. The use of smaller abutment had no influence on stress distribution around implant fixture. The use of smaller abutment diameter than that of implant fixture had no favorable effect on implant supporting tissue at biomechanical consideration.

Analysis of stress and distortion that develop during accelerated cooling of plate (가속냉각시 강판에 발생하는 응력 및 변형에 대한 연구)

  • 김호영;김창영;주웅용;장래웅
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.12 no.5
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    • pp.952-958
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    • 1988
  • To analyze the nonflatness and residual stress in accelerated cooled plate, a numerical analysis model has been developed. Two factors, i.e. temperature and phase transformation, are considered in calculating the stress distribution that develops during cooling. The plastic strain and plate-buckling, which are often shown in accelerated cooled plate, were determined from this stress. Mean temperature in through thickness direction and temperature difference in width direction are considered in the model to simplify the calculation. The temperature and stress distribution changes caused by phase transformation are involved in terms of the effective specific heat and the effective thermal expansion coefficient. With the model, accelerated cooling of 10mm(t) $^{*}$3000mm(w) plate was simulated. The condition of accelerated cooling was .deg. C/sec from just after hot rolling to 500.deg. C. The initial temperature-difference ratio, .DELTA.Tr, in width direction is an important factor in evaluating the stress distribution. When .DELTA.Tr is 0.08, buckling occurs during cooling and 7kgf/m $m^{2}$ of residual stress develops at the edge of plate. To secure the flatness, .DELTA.Tr should be less than 0.07. Small scaled cooling test was conducted to verify the exactness of the model and the results proved the usefulness of this numerical analysis model.l.

PV모듈의 전면 유리 두께 변화에 따른 기계강도 특성

  • Choe, Ju-Ho;Jeong, Tae-Hui;Gang, Gi-Hwan;Jang, Hyo-Sik
    • Proceedings of the Korean Vacuum Society Conference
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    • 2013.08a
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    • pp.297.1-297.1
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    • 2013
  • PV모듈은 다수의 태양전지를 상호 연결한 후 라미네이션(Lamination)공정을 통해 오랜 시간 견딜 수 있는 하나의 구조물로 만든 것이다. 외부환경 노출되어 장시간 발전하는 PV모듈은 설하중 풍하중 등 다양한 응력을 받는다. 이러한 외부 응력은 PV모듈 내부의 태양전지를 파손시켜 발전 출력의 감소를 발생 시킬 수 있다. 따라서 기계적 신뢰성을 보장하는 것은 매우 중요하며, PV모듈의 기계적 강도를 향상시키기 위한 연구가 활발히 진행되어지고 있다. 따라서, 본 논문에서는 PV모듈의 기계적, 물리적 변형을 최소화 하고자 PV모듈 전면에 사용되는 강화유리의 두께를 증가시켜 기계하중 시험을 진행하였다. 실험은 K SC IEC 61215의 PV모듈 인증시험 기준에서 제시하는 기계강도 시험과 동일한 방식으로 시험을 실시 하였으며, 전면유리 두께가 3.2 mm, 4 mm, 5 mm인 PV모듈을 사용하여 하중에 대한 최대변형과 출력 변화를 관찰하였으며, EL (electroluminescence) 측정을 통하여 기계강도 실험전 후의 모듈 내부 태양전지 파손 여부를 확인하였다. 이러한 결과는 PV모듈에 대한 내풍압 및 적설하중 등 Field에서 발생될 수 있는 물리적 내구성능을 분석하는데 많은 도움이 될 수 있다.

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A study of Design and Certification for Reduced Speed in Valve (밸브의 감속기 검증 및 설계에 관한 연구)

  • 이명재;안태현;김윤철
    • Proceedings of the KAIS Fall Conference
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    • 2001.11a
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    • pp.111-116
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    • 2001
  • 본 논문에서는 유체기계에서 사용되고 있는 홀로제트밸브의 감속기에 대하여 APM S/W로 시뮬레이션(simulation) 하였다. 수압과 외부의 힘에 의해서 전달되는 베벨기어의 설계검증 및 재설계 관하여 시뮬레이션을 하였다. 도면의 재원을 변경시키지 않고 기어의 수명을 시뮬레이션한 결과 SM45C를 Martempering하여 사용할 시 기어의 수명이 짧아 적절치 못하였고 고주파열처리강, 질화열처리강을 사용할 경우 기어의 수명시간이 12,957-20,983시간 이였고 침탄강을 사용할 시 기어의 수명은 영구적이었고 소재의 경도가 우수할수록 더 많은 허용굽힘응력과 허용접촉응력을 받을 수 있다는 것을 시뮬레이션을 통하여 입증된다. 그리고 기어의 검증결과로 기어를 다시 설계할 경우 고주파나 질화강으로 하여 기어의 잇수가 1-3개만 늘어나고, 피치원의 지름이 4-12mm늘어나면 영구적으로 사용할 수 있고 침탄강을 사용할 시 치폭이 3mm줄어들고, 기어 잇수가 1-3개 줄어들고 피치원의 지름이 4-13mm 줄어들어 감속기를 경량화 시킬 수 있다는 것을 시뮬레이션을 통하여 입증되었다.

Paleostress Inferred from Calcite Twins in the Pungchon Limestone, Joseon Supergroup (조선누층군 풍촌석회암 방해석 쌍정에서 유추된 고응력장)

  • Kang, Seong-Seung;Jang, Bo-An
    • The Journal of Engineering Geology
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    • v.32 no.1
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    • pp.13-26
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    • 2022
  • Calcite twins were analyzed in six oriented samples of the Pungchon limestone, Joseon Supergroup, to reconstruct the paleostress field. The orientations of c-axis of calcite and e twin plane were measured along with the average thickness and numbers of twins, and the widths of calcite grains. Twin strain, mean width, and intensity of twinning, and the relative magnitude and orientations of principal stresses were calculated using Calcite Strain Gauge program. Twin strain, mean width, and intensity of twinning showed ranges of 1.09-15.36%, 0.53-3.72 ㎛ and 21.0-53.1 twim/mm, respectively. Metamorphic temperatures calculated from the twins were 170-200℃, indicating that the twins developed after the Pungchon limestone was uplifted to at least half of the maximum burial depth. Results for five of the samples indicate that the calcite twins formed during two events with principal stress axes of different orientations, while the remaining sample recorded only one event that produced calcite twins. The axis of maximum compressive stress was oriented mainly WNW-ESE to ENE-WSW, and to a lesser degree NW-SE and NE-SW. Comparison of paleostress orientations measured here and in other studies indicates that most twins were produced during the Songrim orogeny. However, the Daebo orogeny and the Bulguksa orogeny also produced calcite twins in the Punchon limestone.

The Fatigue Strength of Steel Bridge Components Attached with Non-load Carrying Out-of Plane Gusset Plate (하중 비전달형 면외 거셋판이 부착된 강교량 부재의 피로강도)

  • Woo, Sang Ik;Jung, Kyoung Sup
    • Journal of Korean Society of Steel Construction
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    • v.10 no.4 s.37
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    • pp.779-788
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    • 1998
  • This paper presents the results of the experimental and analytical investigation for the fatigue strength of welded details frequently used in steel bridges, especially for the details with relatively lower fatigue strength. Considering the measured stress fatigue cracking initiated at toe of the transverse fillet weld joining the gusset plates to the web because of the stress concentration that developed as a result of the geometric conditions and the greater probability of microscopic discontinuities at the fillet weld toe A comparison was made of the stress calculated by considering geometric aspect of bead and measured at same position. They indicate that the geometric conditions of the weld toe result in similar stress concentration on both FEM models and test results. The test results were compared with the fatigue criteria of AASHTO, JSSC specifications. Specimens of 80 and 150mm gusset plate configuration tested either respectively equaled or exceeded the fatigue resistance provided by category D and E of the AASHTO specification. It also satisfied the category F and G of JSSC. Both WG1 and WG3 specimen tend to provide S-N curves with a store near -0.3 less than AASHTO and JSSC.

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Effect of Bone Quality on Insertion Torque during Implant Placement; Finite Eelement Analysis (임플란트 식립 시 골질이 주입회전력에 미치는 영향에 관한 삼차원 유한요소 분석)

  • Jeong, Jae Doug;Cho, In-Ho
    • Journal of Dental Rehabilitation and Applied Science
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    • v.25 no.2
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    • pp.109-123
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    • 2009
  • The aim of the study was to assess the influence of insertion torque of bone quality and to compare axial force, moment and von Mises stress using finite element analysis of plastoelastic property for bone stress and strain by dividing bone quality to its thickness of cortical bone, density of trabecular bone and existence of lower cortical bone when implant inserted to mandibular premolar region. The $Br{\aa}nemark$ MKIII. RP implant and cylindrical bone finite model were designed as cortical bone at upper border and trabecular bone below the cortical bone. 7 models were made according to thickness of cortical bone, density of trabecular bone and bicortical anchorage and von Mises stress, axial force and moment were compared by running time. Dividing the insertion time, it seemed 300msec that inferior border of implant flange impinged the upper border of bone, 550msec that implant flange placed in middle of upper border and 800msec that superior border of implant flange was at the same level as bone surface. The maximum axial force peak was at about 500msec, and maximum moment peak was at about 800msec. The correlation of von Mises stress distribution was seen at both peak level. The following findings were appeared by the study which compared the axial force by its each area. The axial force was measured highest when $Br{\aa}nemark$ MKIII implant flange inserts the cortical bone. And maximal moment was measured highest after axial force suddenly decreased when the flange impinged at upper border and the concentration of von Mises stress distribution was at the same site. When implant was placed, the axial force and moment was measured high as the cortical bone got thicker and the force concentrated at the cortical bone site. The influence of density in trabecular bone to axial force was less when cortical bone was 1.5 mm thick but it might be more affected when the thickness was 0.5 mm. The total axial force with bicortical anchorage, was similar when upper border thickness was the same. But at the lower border the axial force of bicortical model was higher than that of monocortical model. Within the limitation of this FEA study, the insertion torque was most affected by the thickness of cortical bone when it was placed the $Br{\aa}nemark$ MKIII implant in premolar region of mandible.

Ring Shear Characteristics of Waste Rock Materials in Terms of Water Leakage (누수유무에 따른 광산폐석의 링전단특성)

  • Jeong, Sueng Won
    • The Journal of Engineering Geology
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    • v.26 no.3
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    • pp.307-314
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    • 2016
  • Shear characteristics of soils can be investigated using various types of shear stress measuring apparatus. Ring shear tests are often applied for examining the residual shear strength under the unlimited deformation. This paper presents drainage-consolidation-shear velocity dependent undrained shear strengths measured in terms of water leakage. A series of ring shear tests were performed under the constant normal stress (50 kPa) and controled shear velocity ranging from 0.01~1 mm/sec under the undrained condition. As a result, undrained shear strengths are dependent on shear velocity. It exhibits that straining hardening behavior is observed for the shear velocity lower than 0.1 mm/sec; however, the strain softening behavior is observed for the shear velocity higher than 0.1 mm/sec. Water leakage can cause the increase in shear stress irrespective of shear velocity. Shear stress increases with increasing amount of water leakage. It is due to the fact that the small grains and water flow out through the rubble edge in the ring shear box. Repetitive saturation and consolidation processes may minimize the error.