• Proceedings of the Korean Institute Of Construction Engineering and Management
• /
• 2004.11a
• /
• pp.515-520
• /
• 2004

Manufacturing Production System (MPS) has been widely accepted in construction area for the productivity improvement. However, the MPS does not always provide cost and time saving. It often caused more delays and increased project cost. Therefore the use of the MPS technique, systematic decision-making process is needed by reviewing various project parameters such as cost and time. This study includes extensive literature reviews and case studies on MPS. As a result, a decision-making model is proposed. The decision-making flowchart and decision-making model are developed in three steps: (1) identification and categorization of decision-making factors; (2) calculations of benefits, cost, and duration in accordance with the location and the production capacity of the factory; (3) comparisons of MPS and on-site assembly by varying the locations and sizes of the factory

• Journal of mucopolysaccharidosis and rare diseases
• /
• v.5 no.1
• /
• pp.17-21
• /
• 2021

Hunter syndrome or mucopolysaccharidosis type II (MPS-II) (OMIM 309900) is a rare lysosomal storage disorder caused by deficiency in the activity of the enzyme iduronate-2-sulfatase. This enzyme is responsible for the catabolism of the following two different glycosaminoglycans (GAGs): dermatan sulfate and heparan sulfate. The lysosomal accumulation of these GAG molecules results in cell, tissue, and organ dysfunction. Patients can be broadly classified as having one of the following two forms of MPS II: a severe form and an attenuated form. In the severe form of the disease, signs and symptoms (including neurological impairment) develop in early childhood, whereas in the attenuated form, signs and symptoms develop in adolescence or early adulthood, and patients do not experience significant cognitive impairment. The involvement of the skeletal-muscle system is because of essential accumulated GAGs in joints and connective tissue. MPS II has many clinical features and includes two recognized clinical entities (mild and severe) that represent two ends of a wide spectrum of clinical severities. However, enzyme replacement therapy is likely to have only a limited impact on bone and joint disease based on the results of MPS II studies. The aim of this study was to review the involvement of joints in MPS II.

• Journal of the military operations research society of Korea
• /
• v.25 no.1
• /
• pp.29-36
• /
• 1999

In this paper, we are concerned with the K-shortest loopless path problem. The MPS algorithm, recently proposed by Martins et al., finds paths efficiently because it solves the shortest path problem only one time unlike other algorithms. But its computational complexity has not been known yet. We propose a few techniques by which the MPS algorithm can be implemented efficiently. First, we use min-heap data structure for the storage of candidate paths in order to reduce searching time for finding minimum distance path. Second, we prevent the eliminated paths from reentering in the list of candidate paths by lower bounding technique. Finally, we choose the source mode as a deviation node, by which selection time for the deviation node is reduced and the performance is improved in spite of the increase of the total number of candidate paths.

• Clinical and Experimental Pediatrics
• /
• v.59 no.sup1
• /
• pp.37-40
• /
• 2016

Mucopolysaccharidosis type III (MPS III) is a rare genetic disorder caused by lysosomal storage of heparan sulfate. MPS IIIB results from a deficiency in the enzyme alpha-N-acetyl-D-glucosaminidase (NAGLU). Affected patients begin showing behavioral changes, progressive profound mental retardation, and severe disability from the age of 2 to 6 years. We report a patient with MPS IIIB with a long-term follow-up duration. He showed normal development until 3 years. Subsequently, he presented behavioral changes, sleep disturbance, and progressive motor dysfunction. He had been hospitalized owing to recurrent pneumonia and epilepsy with severe cognitive dysfunction. The patient had compound heterozygous c.1444C>T (p.R482W) and c.1675G>T (p.D559Y) variants of NAGLU. Considering that individuals with MPS IIIB have less prominent facial features and skeletal changes, evaluation of long-term clinical course is important for diagnosis. Although no effective therapies for MPS IIIB have been developed yet, early and accurate diagnosis can provide important information for family planning in families at risk of the disorder.

• BMB Reports
• /
• v.38 no.5
• /
• pp.591-594
• /
• 2005

One of the small proteins from Helicobacter pylori, HP1242, was investigated by the solution nuclear magnetic resonance (NMR) spectroscopy. HP1242 is known as a 76-residue conserved hypothetical protein and its function cannot be identified based on sequence homology. Here, the results of the backbone $^1H$, $^{15}N$, and $^{13}C$ resonance assignments of the HP1242 are reported using double- and triple-resonance techniques. About 95% of all of the $^1HN$, $^{15}N$, $^{13}CO$, $^{13}C{\alpha}$, and $^{13}C{\beta}$ resonances that cover 75 non- Proline residues of the 76 residues are clarified through sequential- and specific- assignments. In addition, three helical regions were clearly identified on the basis of the resonance assignments.

• Advances in environmental research
• /
• v.1 no.2
• /
• pp.167-179
• /
• 2012

Pistachio shell (Pistacia vera) (PS), a low-cost material, has been utilized for the removal of the Cr(VI) ions after treatment with citric acid. Batch experimental steps were applied to obtain Cr(VI) ion adsorption details for the equilibrium between Cr(VI) and modified pistachio shell (MPS). The influences of contact time, pH, adsorbent dose and initial chromium concentration on the adsorption performance of MPS was investigated in detail. The results displayed that adsorption of Cr(VI) by MPS reached to equilibrium after 2 h and after that a little change of Cr(VI) removal efficiency was observed. The sorption percent is higher at lower pH and lower chromium concentration. Two possible mechanisms for reduction of Cr(VI) to Cr(III) can be suggested in Cr(VI) removal. In the first mechanism, Cr(VI) is reduced to Cr(III) by surface electron-donor groups of the adsorbent and the reduced Cr(III) forms complexes with adsorbent or remains in the solution. This Cr(III) is not adsorbed by adsorbent at pH 1.8. But in second mechanism, the adsorption-coupled reduction of Cr(VI) to Cr(III) occurred on the adsorbent sites. The equilibrium sorption capacity of Cr(VI) ion after 2 h was 64.35 mg/g for MPS.

• Polymer(Korea)
• /
• v.30 no.1
• /
• pp.75-79
• /
• 2006

Silica nanoparticles for polymeric dental restorative composites were prepared by Stober method, and then the effects of surface treatment of silica particles with Lmethacrylofpropyltrimethofsilane $(\gamma-MPS)$ on the dispersity of the silica particles in the organic matrix was investigated. Particles having various average size were prepared by using controlled amounts of tetraethylorthosilicate(TEOS), water, and catalyst and by changing solvent used for reaction. The site of particles prepared by using methanol as solvent was smaller than that prepared by using ethanol as solvent. In addition, the size of particles was increased by decreasing amounts of water and by increasing amounts of TEOS and catalyst. Hydrophobic silica nanoparticles was prepared by reacting hydrophilic nanoparticles with $\gamma-MPS$ to improve interfacial properties with organic matrix. Amounts of $\gamma-MPS$ per unit mass of the particles was increased by decreasing particle size. even though the amount of $\gamma-MPS$ per specific surface area were nearly the same regardless of the particle size. The dispersity of the silica particles in the organic matrix was improved when the surface treated silica particles were used for preparing the polymeric dental restorative composites.

• Fire Science and Engineering
• /
• v.29 no.2
• /
• pp.33-38
• /
• 2015

For the purpose of high-pressure and suction of fixed amount, the development of ultra-high pressure rotating helical gear positive displacement pump with no clearance had been proceeded. The CFD analysis was performed to verify the internal pressure and the discharge flow velocity of the pump. Accordingly, a flow analysis were performed by FVM technique and we were unable to obtain a successful result since the fluid domain is separated because the grid is not configured in a row in FVM flow analysis of the fully enclosed type without clearance. Because of these problems, the flow analysis was performed by MPS method which grid configuration is not needed and the internal pressure and the discharge flow velocity of the pump were confirmed through the MPS flow analysis. At 1,000 rpm rotation speed of the rotor, the minimum internal pressure of the pump was 19.5 bar, maximum pressure was 44.6 bar and average pressure was 33.9 bar. And the minimum discharge flow velocity was 64.5 m/s, maximum discharge flow velocity was 84.8 m/s and average discharge flow velocity was 76.1 m/s. Through this study, we could confirm that MPS method was more suitable than FVM method in terms of flow analysis with no clearance. In addition, the relationship of the flow velocity according to the change of ultra-high pressure rotating helical gear positive displacement pump could be identified through this study.

• Journal of the korean academy of Pediatric Dentistry
• /
• v.46 no.2
• /
• pp.139-146
• /
• 2019

This study aimed to analyze the association of midpalatal suture (MPS) maturation stages with skeletal maturation and age and to obtain references for establishing a treatment plan for rapid maxillary expansion (RME). Cone-Beam Computed Tomography (CBCT) images from 480 children (240 boys, 240 girls) aged 7 - 15 years were obtained. MPS maturation stages and cervical vertebral maturation indicator (CVMI) were evaluated, and the correlations between MPS maturation stages, CVMI, and age were determined using the Spearman's correlation test. The positive likelihood ratio (LHR) of CVMI for MPS maturation stages was calculated. MPS maturation stages and CVMI showed a strong correlation. Especially, CVMI 1 - 3 showed positive LHR greater than 10 for the diagnosis of stages A - C. MPS maturation stages and age were correlated strongly in girls and moderately in boys. Conventional RME produces the most favorable skeletal effect at CVMI 1 - 3 or those up to 12 years of age and fewer skeletal effects at CVMI 4 or at 13 years of age in girls and 13 - 15 years in boys. It is recommended to evaluate MPS maturation stages using CBCT before RME application at CVMI 5, 6 or at 14, 15 years of age in girls.

• Child Health Nursing Research
• /
• v.17 no.1
• /
• pp.58-67
• /
• 2011

Purpose: This study was done to explore the meaning of joys and sorrows in mothers of children with Mucopolysaccharidosis (MPS). Methods: The participants were 9 mothers who each had a child with MPS. Data were gathered using in-depth interviews. The interviews were recorded and transcribed verbatim. Data were analyzed using Colaizzi method. Results: The significant results from analyzing the interviews can be grouped into 12 concept descriptions, and 5 theme clusters. The essential theme clusters for the experience of the mothers were 'hopelessness about this rare disease', 'guilt because of the disease being hereditary, 'endless courses of treatment', 'wounds in the relationship', and 'relative composure of mind'. Conclusion: The finding of this study offer profound information on joys and sorrows experienced by mothers of children with MPS and provide basic data for developing nursing intervention strategies for the mothers of children with rare diseases.