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The BioFlex System as a Dynamic Stabilization Device : Does It Preserve Lumbar Motion?

  • Zhang, Ho-Yeol;Park, Jeong-Yoon;Cho, Bo-Young
    • Journal of Korean Neurosurgical Society
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    • v.46 no.5
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    • pp.431-436
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    • 2009
  • Objective : This study examines whether functional motion is present at one or more years after Bioflex System placement. BioFlex System is a flexible rod system which has been used to preserve motion at the area of implantation. There has not been a scientific study showing how much motion is preserved after implantation. Methods : A total of 12 consecutive patients underwent posterior dynamic stabilization using the BioFlex System. Six patients were treated using a L3-4-5 construct and other six patients using a L4-5-S1 construct. Follow-up ranged from 12 to 33 months and standing neutral lateral, extension, flexion and posteroanterior (PA) radiographs were obtained at 3, 6, 9, and 12 months and at more than 12 months postoperatively. Range of motion (ROM), whole lumbar lordosis, and ROMs of motion segments from L2 to S1 were determined. Results : Patients with a L3-4-5 construct demonstrated a decrease in mean ROM for whole lumbar decreased from 40.08 to 30.77. Mean ROM for L3-4 (6.12 to 2.20) and L4-5 (6.55 to 1.67) also decreased after one year. Patients with a L4-5-S1 construct demonstrated L4-5 (8.75 to 2.70) and L5-S1 (9.97 to 3.25) decrease of mean ROM at one year postoperatively. Lumbar lordosis was preservep at both L3-4-5 and L4-5-S1 constructs. Clinical results showed significant improvements in both study groups. Conclusion : The present study provides preliminary information regarding the BioFlex motion preservation system. We conclude that the BioFlex System preserves functional motion to some degree at instrumented levels. However, although total lumbar lordosis was preserved, ROMs at implantation segments were lower than preoperative values.

Magnetic Resonance Imaging for Each Type of Herniated Lumbar Intervertebral Disc (요추 추간판 탈출증의 유형별 자기공명영상 소견)

  • Kim, Ham-Gyum
    • Journal of radiological science and technology
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    • v.22 no.1
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    • pp.27-33
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    • 1999
  • The classification of herniated intervertebral lumbar disc type is clinically important, as treatment method may be slightly different according to the type of herniated intervertebral disc. When 450 patients who suffered from herniated intervertebral lumbar disc were tested with Magnetic Resonance Imaging (MRI) to find out the type of herniated disc, the following findings were given : 1. The age of the patients investigated ranged from 15 to 83, and their mean age was 40. 2. The male patients were twice as many as the female patients, since the ratio of males to females was 300 : 150. 3. 118 patients suffered from a single herniated disc, and 332 patients were attacked with multi-herniated disc. 4. The types of single herniated disc were a protrusion for 50 patients (40%) and an extrusion for 40 patients (34%). The part of being herniated was an intervertebral disc between $L_4-L_5$ for 95 patients(80%) and the same disc between $L_5-S_1$ for 22 patients(19%). 5. The types of multi : -herniated disc were an protrusion for 67 patients(20%) and an extrusion for 70 patients(21%). Besides, 90 patients (28%) were the case that protrusion and extrusion coexisted simultaneously. The parts of being herniated were $L_3-L_4,\;L_4-L_5$ and $L_5-S_1$ for 53 patients(16%), $L_3-L_4$ and $L_4-L_5$ for 57 patients(17%), and $L_4-L_5$ and $L_5-S_1$ for 139 patients(42%).

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A Study on the Ingredients in the Sap of Acer mono MAX. and Betula costata T. in Mt. Jiri Area -On the Components of Mineral and Sugar- (지리산지역 고로쇠나무 및 거제수(거자수) 나무의 수액성분에 관하여 -Mineral과 Sugar성분에 관하여-)

  • 서화중;김충모;정두례
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.20 no.5
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    • pp.479-482
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    • 1991
  • The medical use of Acer mono MAX. and Betula costata T. sap has had the long history in Korea. So the mineral and sugar contents of these sap gathered in Mt. Jiri area at spring were analyzed to investigate the scientific base of folk remedies by using ion liquid chromatography and high performance liquid chromatography. The values of chlorine and sulfate in Acer mono MAX. were 11.5 mg/l and 176.7 mg/l, and in Betula costata T. 26.5 mg/l and 162.4 mg/l, respectively. The values of potassium, sodium, calcium and magnesium in Acer mono MAX. were 67.9 mg/l, 5.6 mg/l, 73.8 mg/l and 4.5 mg/l, and in Betula costata T. were 152.1 mg/l, 9.7 mg/l, 39.2 mg/l and 5.7 mg/l, respectively. The values of copper, zinc and manganese in Acer mono MAX. were 0.057 mg/l, 0.483 mg/l and 5.071 mg/l, and copper, zinc, mangances and iron in Betula costata T. were 0.038 mg/l, 1.584 mg/l, 4.354 mg/l and 2.511 mg/l, respectively. The values of sucrose in Acer mono MAX. were 27.29 mg/l, glucose and fructose in Betula costata T. were 0.97 g/l and 3.05 g/l, respectively.

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Choline and Betaine Concentrations in Breast Milk of Korean Lactating Women and the Choline and Betaine Intakes of Their Infants (한국 수유부 유즙의 콜린과 베타인 농도 및 영아의 콜린과 베타인 섭취량)

  • Jeong, Han-Ok;Suh, Yoon-Suk;Chung, Young-Jin
    • Journal of Nutrition and Health
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    • v.43 no.6
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    • pp.588-596
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    • 2010
  • Most nutrients taken by pregnant women are secreted into their breast milk. Food contains choline together with betaine, and in human body choline is oxidized to betaine which transfer methyl group. The aim of the study was to estimate the concentrations of choline and betaine in breast milk of Korean lactating women and the choline and betaine intakes of their infants. Total choline, free choline and betaine concentrations in breast milk of some lactating women living in Daejon Metropolitan city were analyzed every month by using HPLC-MS and enzymatic method during the first five months. Total choline concentrations of breast milks were 157.64 mg/L (1.52 mmol/L), 157.83 mg/L (1.52 mmol/L), 165.99 mg/L (1.60 mmol/L), 153.67 mg/L (1.48 mmol/L), 145.05 mg/L (1.39 mmol/L) by month after delivery for five months. The concentrations of total choline and free choline in breast milks were not significantly changed for the five months while the betaine concentrations gradually decreased. Daily intake of total choline of the infants appears to be adequate for the infant's requirement according to the US DRI; 124.6 mg/d, 120.9 mg/d, 126.5 mg/d 104.1 mg/d from 2nd to 5th month after birth. Free choline and betaine intakes of the infants were not significantly changed during the four months except showing decrease in betaine intake per kg body weight. Choline intakes of the infants more correlated with choline concentrations of the breast milks (r = 0.982, p = 0.000) than intake amount of the breast milk (r = 0.414, p = 0.028). These results suggest that the choline intake of Korean breast-fed infants appears to be adequate and the intake could be affected by the choline concentration of the breast milk.

Continuous Alcohol Fermentation by a Flocculating Yeast (응집성 효모를 이용한 연속 알코올 발효)

  • 남기두;이인기;조훈호
    • Microbiology and Biotechnology Letters
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    • v.19 no.5
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    • pp.487-490
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    • 1991
  • In this study continuous alcohol fermentation of molasses by the recirculation system has investigated. After cultivation of yeast cells in the YPD medium with increasing the medium concentration from 10 to 183.5 g/l stepwisely, the fermentation medium was replaced by molasses. The maximum cell mass was 25 g/l, and the mean cell mass during the operation was 23.5g/1, which was 3.4 times higher compared with a conventional batch system. The optimum fermentation conditions with feeding molasses of 180 g/l were obtained when the fermentation was carried out at 500 rpm and at the dilution rate of 0.037 $h^{-1}$. Under these conditions we could safely operate the fermentor for 645 h without any trouble. The maximum alcohol productivity was 4.9 g$l\cdot h$ with an alcohol concentration of 53.9 g/l at the dilution rate of 0.091$h^{-1}$.

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Enhancement of Ginsenoside Rg1 and Rg5 Contents in an Extract of Wood-cultivated Ginseng by Lactobacillus plantarum (Lactobacillus plantarum을 이용한 산양삼 추출물의 진세노사이드 Rg1 및 Rg5의 함량 증대)

  • Kwon, Hun-Joo;Cho, Yun-Ji;Kim, Myoung-Dong
    • Microbiology and Biotechnology Letters
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    • v.45 no.4
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    • pp.305-310
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    • 2017
  • Twelve lactic acid bacteria harboring ${\alpha}$-rhamnosidase (EC 3.2.1.40) activity were isolated from traditional Korean foods. The 6 strains (Weissella confuse [n = 1], Lactobacillus pentosus [n = 1], and Lactobacillus plantarum [n = 4]) with the highest rhamnosidase activity were selected for bioconversion of an extract of wood-cultivated ginseng. The L. plantarum MBE/L2990 strain increased ginsenoside content (0.58 mg for Rg1 and 0.24 mg for Rg5) and showed higher bioconversion activity than the control strain L. plantarum KCTC21004 (56% and 42% increase for Rg1 and Rg5, respectively). L. plantarum MBE/L2990 was deposited at the Korean Collection for Type Cultures as Lactobacillus plantarum KCTC18529P.

Characterization of Stormwater Pollutants Runoff in Industrial Complex (강우시 산업단지에서의 오염물질 유출특성)

  • Bang, Ki-Woong;Lee, Jun-Ho;Choi, Jong-Soo
    • Journal of Korean Society of Environmental Engineers
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    • v.22 no.2
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    • pp.341-353
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    • 2000
  • The purpose of this study is to investigate the characteristics of pollutants overflow on storm events and the first flush analysis in industrial complex. Eight sub-basins in the Chongju industrial complex were selected for sampling and study with different characteristics during the period from June 1997 to August 1998. Water quality parameters of stormwater runoff such as $BOD_5$, COD, SS, TKN, $NO_3-N$, $PO_4-P$, TP, n-Hexane extracts, Cr, Cu, Pb and Fe were analyzed. During the storm events, measured concentration ranges of $BOD_5$, COD, SS, $NO_3-N$, TKN, $PO_4-P$, TP, r-Hexane extracts, Cr, Cu, Pb and Fe were 2~324 mg/L, 5~810 mg/L, 1~1,110 mg/L, 0.01~10.89 mg/L, 0.1~59.8 mg/L, 0.08~7.02 mg/L, 0.1~7.8 mg/L, 0.1~1,723.6 mg/L, 0.001~0.363 mg/L, 0.001~0.488 mg/L, 0.001~1.28 mg/L, and 0.26~18.91 mg/L, respectively in the industrial complex watersheds. And a quantitative of first flush has been presented. First flush occurs more frequently as the ratio of impervious area increases.

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Grazing on Bacteria and Algae by Metazoans in the Lake-river Ecosystem (River Spree, Germany)

  • Kim, Hyun-Woo;Joo, Gea-Jae;Walz, Norbert
    • Korean Journal of Ecology and Environment
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    • v.41 no.1
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    • pp.111-115
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    • 2008
  • Direct effects of zooplankton grazing activities on the natural assemblage of bacterioplankton and algae were evaluated at monthly intervals, from June to October of 2000, in the middle part of the River Spree, Germany. We quantified bacterioplankton, algae, zooplankton abundance and measured carbon ingestion rates (CIRs) by zooplankton according to two zooplankton size classes: (i) micro zooplankton (MICZ), ranging in size from 30 to $150{\mu}m$ and including rotifers and nauplii, excluding protozoans and (ii) macrozooplankton (MACZ), larger than $150{\mu}m$ and including cladocerans and copepods. CIRs were measured using natural bacterial and algae communities in the zooplankton density manipulation experiments. Algae biomass (average${\pm}$SD: $377{\pm}306{\mu}gC\;L^{-1}$, n=5) was always higher than bacterial biomass ($36.7{\pm}9.9{\mu}gC\;L^{-1}$, n=5). Total zooplankton biomass varied from 19.8 to $137{\mu}gC\;L^{-1}$. Total mean biomass of zooplankton was $59.9{\pm}52.5{\mu}gC\;L^{-1}$ (average${\pm}$SD, n=5). Average MICZ biomass ($40.2{\pm}47.6{\mu}gC\;L^{-1}$ n=5) was nearly twofold higher than MACZ biomass ($19.6{\pm}20.6{\mu}gC\;L^{-1}$ n=5). Total zooplankton CIRs on algae (average${\pm}$SD: $56.6{\pm}26.4{\mu}gC\;L^{-1}\;day^{-1}$) were $\sim$fourfold higher than that on bacteria $(12.7{\pm}6.0{\mu}gC\;L^{-1}\;day^{-1})$. MICZ CIRs on bacteria $(7.0{\pm}2.8{\mu}gC\;L^{-1}\;day^{-1})$ and algae $(28.6{\pm}20.6{\mu}gC\;L^{-1}\;day^{-1})$ were slightly higher than MACZ CIRs. On average, MICZ accounted for 55.6 and 50.5% of total zooplankton grazing on bacteria and algae, respectively. Considering the MICZ and MACZ CIRs, the relative role of transferring carbon to higher trophic levels were nearly similar between both communities in the lake-river ecosystem.

Cultural Condition of Pseudomonas mendocina for Polysaccharide Production (Pseudomonas mendocina 에 의한 Polysaccharide 생산)

  • Yoo, Jin-Young;Chung, Dong-Hyo
    • Korean Journal of Food Science and Technology
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    • v.21 no.5
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    • pp.619-623
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    • 1989
  • The cultural condition of Pseudomonas mendocina for polysaccharide production was examined. The optimal medium contains following composition per liter of distilled water: Sucrose 23.75g, $(NH_4)_2SO_4$ 1.57g, Yeast extract 0.5g, $KH_2PO_4\;2.9g,\;MgSO_4.\;7H_2O\;1.0g,\;CaCO_3$ 2.5g. The optimum temperature and pH were $30^{\circ}C$ and 6.5. At the condition. Ps mendocina produced 5.98g/l of polysaccharide. The culture viscosity after 3 days was 191mPa.s at $70sec^{-1}$. The product yield $(Y_{p/s})$ and specific productivity $(Q_p)$ were 25.18% and 32.83mg/g-cell/h.

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Role of Endogenous Nitric Oxide in the Control of Salivary Secretion and Blood Flow (타액분비 및 선혈류 조절에 대한 내인성 산화질소의 역할)

  • Nam, Sang-Chae;Kim, Mi-Won;Kim, Won-Jae
    • The Korean Journal of Physiology and Pharmacology
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    • v.1 no.6
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    • pp.809-816
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    • 1997
  • The present study was designed to investigate whether endogenous nitric oxide(EDNO) is involved in submandibular vasodilation and salivation induced by parasympathetic nerve stimulation. Effects of $N^w$-nitro-L-arginine-methyl ester (L-NAME) which blocks the synthesis of EDNO from L-arginine on the submandibular vasodilation and salivation induced by chords stimulation or administration of various vasodilators were examined in anesthetized cats. Effect of L-NAME on $K^+$ efflux induced by carbachol was also examined using the excised submandibular slice in vitro. In the submandibular slices, acetylcholine$(10^{-5}\;mol/L)$ or vasoactive intestinal polypeptide$(VIP,\;10^{-5}\;mol/L)$ increased $NO_2$ contents, which was Prevented by pretreatment with L-NAME. Salivary secretion in response to the chords stimulation$(3\;V,\;1\;msec,\;10{\sim}20\;Hz)$ was completely blocked by treatment with atropine(1 mg/kg). Increased blood flow response to the low frequency(1, 2, 5 Hz) stimulation was significantly reduced, whereas the blood flow induced by the higher frequency(10,20 Hz) stimulation was not affected. Lingual-arterial infusion of L-NAME(100 mg/kg) significantly diminished the vasodilatory and salivary responses to the chorda stimulation at all stimuli frequencies used. Intra-arterial infusion of L-NAME(100 mg/kg markedly diminished the vasodilatory responses to acetylcholine$(5\;{\mu}g/kg)$, VIP$(5\;{\mu}g/kg)$ or bradykinin$(5\;{\mu}g/kg)$. In the excised submandibular slice, $K^+$ efflux in response to carbachol$(10^{-5}\;mol/L)$ was significantly decrease by pretreatment with L-NAME$(10^{-5}\;mol/L)$. In the isolated submandibular artery precontracted with phenylephrine$(10^{-5}\;mol/L)$, the vasorelaxation induced by ACh$(10^{-7}\;mol/L)$ was reversed into a contraction by methylene blue$(10^{-4}\;mol/L)$. These results suggest that EDNO may play an important role in vasodilation and secretion of the submandibular gland.

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