• 한국안전학회지
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• 제33권3호
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• pp.1-7
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• 2018

Recently, various engineering approaches have been widely used in the accident investigation field to identify the cause of the accident and to predict damage by accident. Computational analysis is the most commonly used method of accident investigation technique. This technique is mainly used to identify the mechanism of the accident generation and to determine the cause when it is difficult to reproduce the situation at the time of the accident or when it is impossible to perform a reproduction experiment. In this study, The gas explosion analysis for LPG explosion accident generated by defect of the blocking action was performed to determine the accident object, gas leakage amount and predicted the damage caused by the accident using 3D laser scanner and FLACS program. We can quantify the explosive power by LPG gas accident and predict the gas leakage amount, damage by accident and evaluate the stability of the structure through this study. In the future, This method can be widely used in the field of gas safety by improving the reliability and validity of the analysis.

• International Journal of Oral Biology
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• 제49권1호
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• pp.18-25
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• 2024

Despite advancements in therapeutic approaches, radiotherapy and cisplatin-based chemotherapy remain primary noninvasive treatments for patients with oral squamous cell carcinoma (OSCC). Moreover, the 5-year survival rate for patients with OSCC has remained almost unchanged for several decades, and many side effects of chemotherapy still exist. In this study, three-dimensional (3D) models of OSCC were established using fibroblasts, and the efficacy of various biological inhibitors was evaluated. A culture of epithelial cells with two types of fibroblasts (hTERT-hNOFs and cancer-associated fibroblasts) within a type I collagen matrix resulted in the formation of a continuous layer of tightly packed cells compared to models without fibroblasts. Furthermore, the effects of biological chemicals, including Y27632, latrunculin A, and verteporfin, on these models were investigated. The stratified formation of the epithelial layer and invasion in OSCC 3D-culture models were effectively inhibited by verteporfin, whereas invasion was weakly inhibited by Y27632 and latrunculin. Collectively, the developed OSCC 3D-culture models established with fibroblasts demonstrated the potential for drug screening, with verteporfin showing promising efficacy.

• 농업과학연구
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• 제43권1호
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• pp.72-79
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• 2016

It has long been known that nutritional and environmental influences during the early developmental period affect the biological mechanisms which determine animal metabolism. This phenomenon, termed 'metabolic imprinting', can cause subtle but long-lasting responses to prenatal and postnatal nutrition and even be passed onto the next generation. A large amount of research data shows that nutrient availability, in terms of quantity as well as quality, during the early developing stages can decrease the number of newborn piglets and their body weight and increase their susceptibility to death before weaning. However, investigation of potential mechanisms of 'the metabolic imprinting' effect have been scant. Therefore, it remains unknown which factors are responsible for embryonic and early postnatal nutrition and which factors are major determinants of body weight and number of new born piglets. Intrauterine undernutrition, for example, was studied using a rat model providing dams 50% restricted nutrients during pregnancy and the results showed significant decreases in birth weight of newborns. This response may be a characteristic of a subset of modulations in embryonic development which is caused by the metabolic imprinting. Underlying mechanisms of intrauterine undernutrition and growth retardation can be explained in part by epigenetics. Epigenetics modulate animal phenotypes without changes in DNA sequences. Epigenetic modifications include DNA methylation, chromatin modification and small non-coding RNA-associated gene silencing. Precise mechanisms must be identified at the morphologic, cellular, and molecular levels by using interdisciplinary nutrigenomics approaches to increase pig production. Experimental approaches for explaining these potential mechanisms will be discussed in this review.

• 한국음향학회지
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• 제24권5호
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• pp.294-300
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• 2005

지금까지 근거리 다중 표적에 대한 위치 추적은 2차원 MUSIC (MUltiple Signal Classification) 기법 등으로 표적 의 위치를 추정하여 JPDA (Joint Probabilistic Data Association) 필터 등의 순차적 상태 추정 알고리즘을 적용해 왔다. 그러나 이러한 방법은 데이터 연관 과정을 해결해야할 뿐 아니라 샘플 기간마다 표적의 위치를 추정하기 위해 많은 격자를 탐색해야 하므로 연산량 부하가 가중된다 또한 다수의 표적이 근접하여 위치할 경우 각 표적에 대한 위치 추정 오차가 크게 되어 위치 추적 성능이 저하되는 단점이 있다. 본 논문에서는 근거 리 음장 (near field)에서의 선배열 센서 출력 신호 공분산 행렬로부터 위치 변위를 추정하여 근거리 다중 표적에 대한 위치 추적이 가능한 알고리즘을 제안하였으며, 근접 및 교차 표적에 대한 모의실험을 수행하여 그 성능의 우수함을 확인하였다.

• Wind and Structures
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• 제34권1호
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• pp.151-159
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• 2022

The aerodynamics of blunt bodies with separation at the sharp corner of the leading edge and reattachment on the body side are particularly important in civil engineering applications. In recent years, a number of experimental and numerical studies have become available on the aerodynamics of a rectangular cylinder with chord-to-thickness ratio equal to 5 (BARC). Despite the interest in the topic, a widely accepted set of guidelines for grid generation about these blunt bodies is still missing. In this work a new, well resolved Direct Numerical Simulation (DNS) around the BARC body at Re=3000 is presented and its results compared to previous DNSs of the same case but with different numerical approaches and mesh. Despite the simulations use different numerical approaches, mesh and domain dimensions, the main discrepancies are ascribed to the different grid spacings employed. While a more rigorous analysis is envisaged, where the order of accuracy of the schemes are kept the same while grid spacings are varied alternately along each spatial direction, this represents a first attempt in the study of the influence of spatial resolution in the Direct Numerical Simulation of flows around elongated rectangular cylinders with sharp corners.

• 한국컴퓨터정보학회논문지
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• 제26권1호
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• pp.103-110
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• 2021

본 논문에서는 5G 무선 네트워크 D2D 시스템에서 수행될 수 있는 두 가지 액세스 제어 메커니즘들을 비교해 보고 효과적인 액세스 제어 기법을 제안한다. 현재 5G D2D 시스템에서는 액세스 제어 기법이 표준 규격에 제정 되어 있지 않고 있으나, 두 가지 액세스 제어 기법들이 가능하다. 하나의 방식으로는 UE-to-Network Relay 기반의 액세스 제어 기법이고, 다른 하나의 방식으로는 Remote UE 기반의 액세스 제어 기법이다. 전자의 경우는 UE-to-Network Relay가 액세스 제어 검사를 수행하는 것이며, 후자의 경우는 Remote UE가 액세스 제어 검사를 직접 수행하는 방식이다. 실험 평가 결과, 본 논문에서는 5G 무선 네트워크 D2D 시스템에서 효율적인 액세스 제어 방안으로써 Remote UE 기반의 액세스 제어 기법을 최종 제안한다. Remote UE 기반의 액세스 제어 기법은 UE-to-Network Relay 기반의 액세스 제어 기법이 비하여, 신호 오버헤드를 최소화하고, 서로 액세스 제어 기능들이 다른 경우 보다 효율적인 액세스 제어 검사를 수행할 수 있다.

• 지구물리와물리탐사
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• 제15권1호
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• pp.23-32
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• 2012

저류층 감시(reservoir monitoring)를 위해서는 시간경과(time-lapse) 탄성파 자료들을 비교하는 방법이 주로 사용되며, 시간경과 탄성파자료로부터 저류층에서의 변화에 의한 차이만을 추출해 내는 기술이 핵심이라 할 수 있다. 본 논문에서는 시간경과 탄성파자료로부터 저류층에서의 변화만을 추출하기 위한 방법으로 기존의 교차균등화(crossequalization) 방법과 개선된 최적화 방법을 실험 및 비교해 보았다. 기존의 방법론으로는 주파수 띠폭 균등화(bandwidth equalization)와 위상보정(phase rotation)을 주파수 영역과 시간 영역 그리고 혼합영역에서 각각 구현하여 그 성능을 비교해 보았으며, 이러한 방법들이 갖고 있는 고주파수가 손실되는 한계를 극복할 수 있는 제약적 최적화 필터링(constrained optimum filtering) 방법론을 제안 및 실험해 보았다. 새로이 제안된 제약적 최적화 필터링 방법은 최적화된 맞춤필터를 구함으로써 저류층 변화성분의 주파수띠폭을 넓히는데 개선된 결과를 보여주었다.

• Advances in concrete construction
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• 제13권 2호
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• pp.199-213
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• 2022

Experimental and discrete element approaches were used to examine the effects of F shape non-persistent joints on the failure behaviour of concrete under uniaxial compressive test. concrete specimens with dimensions of 200 cm×200 cm×50 cm were provided. Within the specimen, F shape non-persistent joint consisting three joints were provided. The large joint length was 6 cm, and the length of two small joints were 2 cm. Vertical distance between two small joints change from 1.5 cm to 4.5 cm with increment of 1.5 cm. In constant joint lengths, the angle of large joint change from 0° to 90° with increments of 30°. Totally 12 different models were tested under compression test. The axial load rate on the model was 0.05 mm/min. Concurrent with experimental tests, numerical simulation (Particle flow code in two dimension) were performed on the models containing F shape non-persistent joint. Distance between small joints and joint angles were similar to experimental one. the results indicated that the failure process was mostly governed by both of the Distance between small joints and joint angles. The axial loading rate on the model was 0.05 mm/min. The compressive strengths of the samples were related to the fracture pattern and failure mechanism of the discontinuities. Furthermore, it was shown that the compressive behaviour of discontinuities is related to the number of the induced tensile cracks which are increased by increasing the joint angle. In the first, there were only a few acoustic emission (AE) hits in the initial stage of loading, and then AE hits rapidly grow before the applied stress reached its peak. Furthermore, a large number of AE hits accompanied every stress drop. Finally, the failure pattern and failure strength are similar in both approaches i.e., the experimental testing and the numerical simulation approaches.

• 한국전자파학회논문지
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• 제17권2호
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• pp.134-138
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• 2006

S-대역 SPST MMIC 스위치의 격리도 특성을 두 서로 다른 RF 결합 방법 인 마이크로스트립(microstirp)과 접지 코플라나 웨이브가이드(GCPW) 선로로 구성하여 분석하였다. 스위치의 온-오프 격리도는 마이크로스트립 설계에 비하여 접지 코플라나 웨이브가이드 선로를 사용하는 경우 5.8 dB 개선되었고, 접지 코플라나 웨이브가이드 선로에 코플라나 와이어본드 결합을 적용하는 경우 6.9 dB 더 향상된 격리도 특성을 3.4 GHz의 주파수에서 얻을 수 있었다. 측정된 삽입 손실 및 IMD3는 $3.2{\sim}3.6\;GHz$ 대역에서 1.94 dB보다 작았으며, 64 dBc보다 큰 특성을 얻었다.

• 한국초전도ㆍ저온공학회논문지
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• 제22권4호
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• pp.31-39
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• 2020

Power cables made of high temperature superconductors (HTS) are considered as most advanced applications of superconductivity for electro-energetics. Several cables made of the First Generation (1G) HTS wires have been produced and installed to electrical grids worldwide. Power cables made of the Second Generation HTS wires (2G or Coated Conductors) are in active development. Most basic principles of HTS power cables development have been published in many works since 90-ties. In this Review we would like to present our new developments mostly directed to 2G HTS compact power cables. We are presenting the methods to optimize a design of 2G AC compact power cable providing uniform current distribution among cable layers and the production technology approaches to implement such a design. AC losses measurements in such cables and other test methods are described. Some problems of the development 2G HTS power cables with small diameters are discussed. We presented as examples designs, developments and test results of two major coaxial cables designs: single-phase (cable core and a shield) and three-phase (triaxial: with three coaxial phases).