• Journal of Preventive Veterinary Medicine
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• v.43 no.4
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• pp.214-220
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• 2019

Although canine brucellosis has been known to be an important re-emerging zoonosis, the pathophysiological mechanisms of Brucella canis infection remains clues to be solved. Different culture models, single and co-culture models, were constructed with canine epithelial cells, D17 and macrophage, DH82 to investigate the induction of immune responses in in vivo B. canis infection. Expression of genes related with induction of immune responses, Th1, Th2 and Th17, was compared in the two different models after the bacterial infection. In this study, expression of cytokine genes, IL-1β, IL-5, IL-6, IL-10, IL-23, and TNF-α was quantified in the DH82 at different time points using RT-qPCR in the two different culture systems after the infection. Cytokine genes related with Th1, IL-1β and TNF-α and Th17, IL-6 and IL-23 were expressed with time-dependent manners in the both systems (p<0.05). However, increase of Th2-related cytokine genes expression was not detectable in the both systems by comparison with control. The expression of Th1 and Th17 related cytokine genes was earlier in single cell culture than those in co-culture model (p<0.05). In general, amounts of the expressed genes were shown higher in single cell model than those in co-culture models. This study indicate that Th1 and Th17-associated immune responses are central to B. canis infection in dogs. In addition, it suggests a specific role of epithelial cells in the B. canis infection in vivo, which should resolved in the further study.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.37 no.1
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• pp.247-253
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• 2017

Accurate flood frequency and magnitude estimation has a critical role in flood risk management and damage reduction. In United States, Log Pearson Type-III (LP-III) distribution with method of moments for parameter estimation has been uniformly and consistently employed in estimating design floods. After the first version of flood frequency guidelines (Bulletin 15) was published in 1967, the revised version Bulletin 17B has been employed since 1982 up to now. A new version of flood frequency guidelines, Bulletin 17C, is prepared and about to come out soon. In the current study, we analyzed the new features of the upcoming Bulletin 17C and presented case studies applying its new features. From the presented results, we see what critical components in the new design flood frequency guideline we could learn.

• Journal of applied mathematics & informatics
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• v.17 no.1_2_3
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• pp.307-314
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• 2005

In this paper we consider positive solutions of the following difference equation $$x_{n+l}\;=\;min[{\frac{A}{x_{n}},{\frac{B}{x_{n-2}}}],\;A,B\;>\;0$$. We prove that every positive solution is eventually periodic. Also, we present here some results concerning positive solutions of the difference equation $$x_{n+l}\;=\;min[{\frac{A}{x_{n}x_{n-1}{\cdots}x_{n-k}},{\frac{B}{x_{n-(k+2)}{\cdots}x_{n-(2k+2)}}],\;A,B\;>\;0$$.

• East Asian mathematical journal
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• v.17 no.2
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• pp.233-237
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• 2001

The authors aim at presenting summation formulas of Appell's function $F_1$: $$F_1(a;b,b';1+a+b-b'+i;1,-1)\;(i=0,\;{\pm}1,\;{\pm}2,\;{\pm}3,\;{\pm}4,\;{\pm}5)$$, which, for i=0, yields a known result due to Srivastava.

• The Pure and Applied Mathematics
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• v.5 no.1
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• pp.17-21
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• 1998

In [5], Zhu introduces a bounded operator T from $L^{\infty}$(D) into Bloch space B. In this paper, we will consider the generalized Bloch spaces $B_{q}$ and find bounded operator from $L^{\infty}$(D) into $B_{q}$.

• Journal of Welding and Joining
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• v.18 no.6
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• pp.62-67
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• 2000

Metallurgical characteristics of bonded region and high temperature mechanical properties of heat resistant alloy, Fe-35Ni-26Cr during liquid phase diffusion bonding were investigated employing AM17 insert metal. The insert metal for bonding, AM17 was newly developed Ni-base metal using interpolation method. Bonding of specimens were carried out at 1,403~1,463K for 600s in vacuum. The microconstituents in the bonded interlayer disappeared in the bonding temperature over 1,423K. The microstructures, alloying elements and hardness distribution in the base metal. The tensile strength and elongation of the joints at elevated temperatures were the same level as one of the base metal in the bonding temperature over 1,423K. The creep rupture strength and rupture lives of joints were almost identical to those of base metal.

• YAKHAK HOEJI
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• v.26 no.1
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• pp.9-23
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• 1982

The structure of 1-butyl-3-sulfanyl urea, ($C_{11}H_{17}N_{3}O_{3}S$) carbutamide has been determined from 575 significant independent reflections collected on an automated four-circle diffractometer. The crystals are orthorhomic, space group, $P2_{1}2_{1}2_{1}$, Z=4, with unit cell dimensions a=9.257 (2), b=9.928 (2), c=15.287 (3)${\AA}$. The structure was solved by the direct methods and refined by least-squares procedure to a final R value of 0.062. Features of the structure include layers of molecules joined by N-H....O hydrogen bond distances ranging from 2.745 to 3.100${\AA}$ involved in a bifurcated hydrogen bond across two fold screw along a and b axes. The atoms forming the urea system are essentially planar.

• The korean journal of orthodontics
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• v.17 no.2
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• pp.289-297
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• 1987

For the comparisons of dental archs and crowdings between musical wind instrument players groups and non-wind instrument players groups, 64 male wind instrument players and 31 non-wind instrument players group were selected. The results of the measurements were as follow. 1 Upper intercanine widths, upper basal arch widths, lower basal arch widths were statistically significant between musical wind instrument players groups (Class A, Class B) and non-wind musical instrument players group. 2 The mean value of upper intercanine width m Class A ($373{\pm}2.3mm$) was greater than than in Class B ($362{\pm}17mm$) and non-wind musical instrument players group($360{\pm}16mm$) 3 The mean value of lower basal arch width m Class B ($422{\pm}25mm$) was greater than that in non wind instrument players group ($395{\pm}28mm$). 4 The differences in the mean values of crowdings between Class A and Class Band non-wind instrument players group were not statistically significant.

• JSTS:Journal of Semiconductor Technology and Science
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• v.17 no.2
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• pp.294-301
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• 2017

This paper presents a low power ${\Sigma}{\Delta}$ modulator for an implantable chip to acquire a bio-signal such as EEG, DBS, and EMG. In order to reduce a power consumption of the proposed fourth order modulator, two op-amps utilized for the first two integrators are reconfigured to drive the second two integrators. The KT/C noise reduction circuit in the first two integrators is employed to enhance SNR of the modulator. The proposed circuit was fabricated in a 0.18 um CMOS n-well 1 poly 6 metal process with the active chip core area of $900um{\times}800um$ and the power consumption of 830 uW. Measurement results were demonstrated to be SNDR of 76 dB, DR of 77 dB, ENOB of 12.3 bit at the input frequency of 250 Hz and the clock frequency of 256 kHz. FOM1 and FOM2 were measured to be 41 pJ/step and 142.4 dB, respectively.

• JSTS:Journal of Semiconductor Technology and Science
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• v.17 no.3
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• pp.341-346
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• 2017

In this paper, we present a 60 GHz on-off keying (OOK) modulator in a 90 nm CMOS. The modulator employs a current-reuse technique and a switching modulation for low DC power dissipation, high on/off isolation, and high data rate. The measured gain of the modulator, on/off isolation, and output 1-dB compression point is 9.1 dB, 24.3 dB, and 5.1 dBm, respectively, at 60 GHz. The modulator consumes power consumption of 18 mW, and is capable of handling data rates of 8 Gb/s at bit error rate of less than $10^{-6}$ for $231^{-1}$ PRBS over a distance of 10-cm with an OOK receiver module.