• Korean Journal of Ecology and Environment
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• v.53 no.4
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• pp.344-354
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• 2020

Identification of the target species of 2-MIB (2-methyllisoborneol) production is crucial in the management of off-flavor problem in the freshwater system. This study was conducted to identify 2-MIB-producing Pseudanabaena strains occurring in the North Han River system using molecular genetic method. Eleven phenotypes of Pseudanabaena were isolated from several mainstream sites of the North Han River, including Sambong-ri, Joam-myun, and Lake Uiam areas. Despite of morphological similarity of the strains, the phylogenetic analysis using 16S rDNA classified them into different species with low genetic similarity (40~55%). Isolated Pseudanabaena strains were converged to four species; Pseudanabaena cinerea, P. yagii, P. mucicola, and P. redekei. Among them, the 2-MIB synthesizing gene (mibC) was detected in P. cinerea, P. yagii, and P. redekei. However, actual 2-MIB production was detected only in P. cinerea and P. redekei based on gas chromatography analysis. This study is the first report of the molecular identification of Pseudanabaena strains and their 2-MIB production potential in Korea. The results of this study provides an evidence of species diversity of Pseudanabaena occurring in the North Han River.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.11
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• pp.6573-6578
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• 2013

Background: The goal of this retrospective study was to evaluate patient characteristics, treatment modalities and prognostic factors in Turkish patients with pancreatic cancer. Materials and Methods: Between January 1997 and December 2012, 64 patients who presented to the Department of Radiation Oncology, Karadeniz Technical University, Faculty of Medicine with a diagnosis of pancreatic cancer were evaluated. The E/K ratio of the cases was 2.4/1 and the median age was 59.6 (32-80) years, respectively. Some 11 cases (18%) were stage 1, 21 (34.4%) were stage 2, 10 (16.4%) were stage 3, and 19 (31.1%) were metastatic. Results: The mean follow-up time was 15.7 months (0.7-117.5) and loco-regional recurrence was noted in 11 (40.7%) who underwent surgery while metastases were observed in 41 patients (66.1%). The median overall survival (OS) was 11.2 months and the 1, 3 and 5-year OS rates were 41.7%, 9.9% and 7.9% respectively. The median disease-free survival (DFS) was 5.2 month and the1, 2 and 5 year DFS were 22.6%, 7.6% and 3.8% respectively. On univariate analysis, prognostic factors affecting OS included status of the operation (p<0.001), tumor stage (p=0.008), ECOG performance status (p=0.005) and CEA level (p=0.017).On multivariate analysis, prognostic factors affecting survival included status of the operation (p=0.033) and age (p= 0.023). Conclusions: In the current study, age and operation status were independent prognostic factors for overall survival with pancreatic patients. Thus, the patients early diagnosis and treatment ars essential. However, prospective studies with more patients are needed for confirmation.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.11
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• pp.4583-4587
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• 2015

Background: The objectives of this study aimed to detect a CYP2B6 polymorphism in de novo cases of acute myeloid leukemia patients and identify any role in disease progression and outcome. Materials and Methods: DNA was isolated from peripheral blood of 82 newly diagnosed acute myeloid leukemia cases and the CYP2B6 G15631T gene polymorphism was assayed by PCR restriction fragment length polymorphism (PCR-RFLP). Results: The frequency of the GG genotype (wild type) was 48 (58.5%) and that of the mutant type T allele was 34 (41.9%). GT genotype heterozygous variants were found in 28 (34%), and TT genotype homozygous variants in 6 (7.3%) cases. We found no significant association between the CYP2B6 G15631T polymorphism and complete response (CR) (p-value=0.768), FAB classification (p-value=0.51), cytogenetic analysis (p-value=0.673), and overall survival (p-value=0.325). Also, there were no significant links with early toxic death (p-value=0.92) or progression-free survival (PFS) (p-value=0.245). Conclusions: Our results suggest that the CYP2B6 polymorphism has no role in disease progression, therapeutic outcome, patient free survival, early toxic death and overall survival in acute myeloid leukemia patients.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.2
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• pp.1109-1117
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• 2015

The purpose of this study was to examine the job-seeking stress of nursing students according to their critical thinking disposition and self-esteem and the relationship of these variables. The subjects in this study were 332 nursing students. The students got $89.57{\pm}9.77$ in critical thinking; $25.11{\pm}2.58$ in self-esteem; and $46.38{\pm}17.67$ in job-seeking stress. There was a positive correlation between critical thinking and self-esteem(r=.294, p<.001), and critical thinking(r=-.240, p<.001) had a significant positive correlation with self-esteem(r=-.209, p<.001). Critical thinking disposition and self-esteem were identified as the variables to affect job-seeking stress, and the two variables had a 35.2% explainability.

• Korean Journal of Weed Science
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• v.10 no.3
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• pp.207-213
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• 1990

Thirty formulations of oxyfluorfen(2-chloro-2,2,2-trifluoro-p-toyl 3-ethoxy-4-nitrophenyl ether were manufactured by adsorption and substitation. Of them 16 formulations n-ere selected because they showed rekatuvely high activity and long durability in the bioassay with (Brassica campestris V.L.) Then, the formulations selected and 4 commercial formulations were tested using Monochoria in pots. As the result, the formulations of polyer 11, elvan 7/40, coal-slag 7/40, zeolite(A), and bentonite(A) were selected because they showed almost complete inhibition of Monochoria even up the 73 days after treatment.

• Journal of Korean Academy of Rural Health Nursing
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• v.16 no.1
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• pp.11-17
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• 2021

Purpose: The purpose of this study was to compare the quality of life and depression in nursing students between Korean and Cambodians. Methods: The subjects of this study were 223 students taking up a four-year nursing course in colleges located in Area A in Korea and Area B in Cambodia. The collected data were analyzed using SPSS 22.0. Results: The total score on quality of life among the Korean students was significantly higher than that of the Cambodian students (t=-4.596, p<.001), while the total score on depression was lower in the Korean students compared to that of the Cambodian students. There was a statistically significant difference in the scores (t=5.179, p<001). When the levels of depression were compared, the difference between the two groups was statistically significant - the Korean students had 92.7% normal and 7.3% mild depression, while the Cambodian students had 80.9% normal and 19.1% mild depression (x²=6.781, p=.009). As a result of analyzing the correlation between the total scores on depression and quality of life, a statistically significant correlation was found in both Korean (r=-.721, p<.001) and Cambodian (r=-.508, p<.001) students. Conclusion: Therefore, a nursing intervention that considers the cultural differences should be developed in order to improve emotional response and quality of life of cambodian students.

• Microbiology and Biotechnology Letters
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• v.34 no.3
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• pp.196-203
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• 2006

Three slime-forming lactic acid bacteria were isolated from Kimchi and shown to produce viscous exopolysaccharides (EPS) in sucrose media. The isolated strains, GJ2, C3 and C11, were identified as Leuconostoc kimchii, Leuconostoc citreum and Leuconostoc mesenteroides, respectively, by examining their metabolic characteristics and determining their 16S rDNA sequences. Leu. kimchii GJ2, Leu. citreum C3 and Leu. mesenteroides C11 exhibited high viability (maintained initial viable cell count of $10^8$ CFU/ml) in 0.05 M sodium phosphate buffer (pH 3.0) for 2 h, in artificial gastric juice for 2 h and in 0.3% oxgall for 24 h. When tested, Leu. kimchii GJ2, in particular, displayed antimicrobial activity against pathogenic microorganisms. Leu. kimchii GJ2, Leu. citreum C3 and Leu. mesenteroides C11 produced 21.49 g/l, 16.46 g/l and 22.98 g/l EPS, respectively, in sucrose (5%) medium. The amount of purified EPS extracted from Leu. kimchii GJ2, Leu. citreum C3 and Leu. mesenteroides C11 was 14.61 g/l, 7.73 g/l and 4.77 g/l, respectively. Although the EPS produced by Leu. kimchii GJ2, Leu. citreum C3 and Leu. mesenteroides C11 differed in viscosity, TLC and HPLC analysis revealed that each contained only one type of monosaccharide, glucose. The average molecular mass of EPS produced by Leu. kimchii GJ2 was 306,606 Da.

• Journal of Digital Convergence
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• v.16 no.10
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• pp.289-299
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• 2018

The purpose of this study was to identify the effects of clinical practice education using delirium checklist for nursing students. The study was used pretest-posttest design with single group with 91 fourth year nursing students. The study measured the delirium knowledge, self-confidence and performance of delirium care using structured questionnaire from August 14 to September 30, 2017. The delirium education was composed of one hour lecture and clinical practice. Clinical practice was applied checklists of delirium assessment and prevention care. In result, significant improvements were found in delirium knowledge(t=-11.23, p<.001), self-confidence(t=-11.00, p<.001) and performance(t=-5.31, p<.001) of delirium care. Based results of this study, it was found that delirium education using checklist improved delirium knowledge, self-confidence and performance levels of delirium care for nursing students.

• Physical Therapy Rehabilitation Science
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• v.2 no.2
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• pp.115-118
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• 2013

Objective: Whole body vibration training is a relatively new approach for enhancement of muscle strength, physical performance, and balance. The aim of this study was to assess the effect of unilateral whole body vibration training. Design: One group pretest-posttest design. Methods: Sixteen healthy, physically active volunteers participated in this study. Whole body vibration was applied with a frequency of 20 Hz and an amplitude of 3 mm for 3 minutes. Muscle performance and static balance were assessed before and after unilateral whole body vibration training. One leg standing broad jump test was measured to determine muscle performance which is closely linked to lower extremity muscle function. The good balance system was used in evaluation static balance. All test were measured 3 times and the average value was analyzed. Results: Jumping length was significantly improved by 0.11m in all participants after intervention (p<0.05). Among static parameters, significant results were observed where in the eyes opened condition, X-speed (medial-lateral sway) changed from 4.20 mm/s to 4.95 mm/s, Y-speed (anterior-posterior sway) changed from 5.77 mm/s to 6.54 mm/s and velocity moment changed from $12.77mm^2/s$ to $13.57mm^2/s$ (p<0.05). In the eyes closed condition, X-speed changed from 4.34 mm/s to 4.85 mm/s, Y-speed changed from 7.84 mm/s to 8.16 mm/s and velocity moment changed from $16.03mm^2/s$ to $16.11mm^2/s$ (p<0.05). Conclusions: Immediate unilateral whole body vibration improved muscle performance but impaired static balance in young adults.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.11
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• pp.7698-7707
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• 2015

The purpose of this study was to investigate self-esteem, empathy, communication skill and clinical competency, and to identify the influencing factors on clinical competency of nursing students. The data was collected using questionnaires from 212 nursing students who were 3rd and 4th years in 2 nursing universities in Daejeon, September 2014. Data was analyzed using Pearson correlation and stepwise multiple regression with IBM SPSS 21. Significant relationships were found among self-esteem, empathy, communication skill and clinical competency in nursing students. The result of stepwise multiple regression indicates that communication skill and self-esteem (F=37.010, p<.001) predicts 26.2% in clinical competency. The most powerful predictor was communication skill(${\beta}$=.384, p<.001), next one was self-esteem(${\beta}$=.283, p<.001). In conclusion, to enhance clinical competency for nursing students, it is necessary to develop and utilize a program that enhances communication skill and self-esteem.