• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.41 no.7
• /
• pp.738-746
• /
• 2016

As the trend of future war has been changed to network centric warfare, tactical data link should be needed for fast and accurate situation awareness. Nowadays, Korean air force conducts military operations by using aircrafts equipped with Link-16. The Link-16 can conduct multiple mission at the same time because it supports multi-net capability. Due to lack of frequency resource, the way to share the frequency with other systems has been studied and using L band with radar is considered as one of the candidates bands. However, the data link can be affected by the interference from radars when it shares the L-band because the L-band in Korea is already assigned to long-range detection radars. In this paper, we evaluate operational possibilities of tactical data link in the L-band based on Link-16.

• The KIPS Transactions:PartA
• /
• v.18A no.6
• /
• pp.265-270
• /
• 2011

Even though 32-bit ISA based microprocessors are widely used more and more, 16-bit ISA based processors are still being frequently employed for embedded systems. Intel 8086, 80286, Motorola 68000, and ADChips AE32000 are the representatives of the 16-bit ISA based processors. However, due to less expressiveness of the 16-bit ISA from its narrow bit width, we need to execute more 16-bit instructions for the same implementation compared to 32-bit instructions. Because the number of executed instructions is a very important factor in performance, we have to resolve the problem by improving the expressiveness of the 16-bit ISA. In this paper, we propose a new pair register allocation algorithm to enhance an original graph-coloring based register allocation algorithm. Also, we explain about both the performance result and further research directions.

• Journal of Gastric Cancer
• /
• v.13 no.3
• /
• pp.157-163
• /
• 2013

Purpose: The aim of this study was to assess clinical correlations with postoperative alteration of p16 DNA methylation, and to clarify whether postoperative changes in the serum DNA methylation status of p16 could be used as a reliable prognostic factor for gastric cancer. Materials and Methods: Fifty-three consecutive gastric adenocarcinoma patients who underwent gastric resection (Chung-Ang University Hospital, Seoul, Korea) were included. DNA methylation of p16 was evaluated by methylation-specific polymerase chain reaction using serum DNA preoperatively and at the 10th postoperative day. The correlation between changes in methylation status and patients' prognosis was analyzed. Results: p16 was methylated in 79.2% of preoperative serum DNA and in 54.7% of postoperative serum DNA, respectively. Methylation in p16 disappeared more frequently in patients who underwent standard D2 lymphadenectomy compared to those who underwent modified D1+ lymphadenectomy (P=0.016). Whereas methylation of preoperative serum DNA was not correlated with survival, patients with postoperative disappearance of p16 methylation showed longer survival than those without postoperative disappearance of p16 methylation in the patients who had gastric cancer with lymph node metastasis (P=0.042). Conclusions: Postoperative disappearance of p16 methylation could be an available prognostic factor for node-positive gastric cancer.

• Journal of the Computational Structural Engineering Institute of Korea
• /
• v.18 no.4 s.70
• /
• pp.347-360
• /
• 2005

The fuel rod instability can be occurred because of the axial and cross flow due to the flow anomaly and/or flow redistribution in the lower core plate region of the pressurized water reactor. The fuel rod vibration due to the hydraulic instability is one of the root causes of fuel failure. The verification on the fuel rod vibration and instability is needed for the new fuel assembly design to verify the fuel rod instability. In this study, the fuel rod vibration and stability analyses were performed to investigate the effect of the grid height, fuel rod support condition, and span adjustment on the fuel rod vibration characteristics for the advanced $16{\times}16$ fuel assembly design. Based on the analysis results, the grid height and grid axial elevation of the advanced $16{\times}16$ fuel assembly design were proposed.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.24
• /
• pp.10803-10808
• /
• 2015

Background: The role of $p16^{INK4A}$ expression in uterine cervix cancer is well established. In the remaining female lower genital tract cancers, the importance of $p16^{INK4A}$ up-regulation is less clear. In our study, we analyzed the role of $p16^{INK4A}$ expression and HPV infection in carcinomas of the vulva and the vagina in Tunisian women. Materials and Methods: We conducted a retrospective study of 30 carcinomas including 15 vulvar squamous cell carcinomas (SCCs) and 15 vaginal SCCs. Immunohistochemistry was used to determine $p16^{INK4A}$ expression. HPV detection and typing was by in situ hybridization. Results: $p16^{INK4A}$ expression was detected in 86.7% of vaginal SCCs with a strong and diffuse immunostaining in 60% of cases, and also in 73.3% of vulvar SCCs with focal immunoreactivity in 53.3% The association between $p16^{INK4A}$ expression and HPV infection was significant in vaginal SCCs (p=0.001) but not vulvar SCCs (p>0.05). Conclusions: $p16^{INK4A}$ expression could be used as a useful marker for HPV positivity in vaginal SCCs similar to that described in uterine cervix cancers. However, our data support the presence of 2 different mechanisms for $p16^{INK4A}$ expression in HPV-related and HPV-unrelated vulvar carcinomas.

• Journal of fish pathology
• /
• v.17 no.2
• /
• pp.91-98
• /
• 2004

This study was performed for the identification of Streptococcus sp. from cultured flounders (Paralichthys olivaceus) showing streptococcosis in the Jeju island. We isolated 10 strains of Streptococcus iniae from the cultured olive flounders with streptococcosis. Isolated strains were identified in S. iniae since they have formed the expected band through performing PCR assay using specific primers, Sin-1 (5'-CTAGAGTACACATGTACT(AGCT)AAG-3') and Sin-2 (5'-GGATTTTCCACTCCCATTAC-3'). In addition to 16S-23S rRNA intergenic spacers (ISR), operon structure of isolated strains showed that all strains had three 16S-23S rRNA ISR band patterns. The 16S-23S rRNA ISR sequence of isolated strains showed 96% sequence identity with S. iniae (GenBank accession number AF 048773). This paper is the first report that S. iniae is associated with streptococcosis of Olive flounder in Korea.

• Korean Journal of Food Science and Technology
• /
• v.35 no.3
• /
• pp.470-474
• /
• 2003

DNA sequence information on small-subunit rRNA gene (16S rDNA) obtained from food-poisoning bacterial culture was used to investigate the presence of bacterial pathogens in food. By reverse dot blot detection method, presence of food-poisoning bacteria could be confirmed on hybridization of digoxigenin-labeled 16S rDNA Polymerase Chain Reaction (PCR) primer product and biotin-labeled specific oligonucleotide probe. Escherichia coli, Bacillus cereus. and Salmonella sp. were used as the representative food-poisoning bacterial microorganisms. An oligonucleotide probe, based on the variable region of 16S rRNA gene, was used as the specific probe. These tools may be more useful than classic biochemical method for rapid identification of contaminated food.

• Journal of the Korean Chemical Society
• /
• v.42 no.4
• /
• pp.443-448
• /
• 1998

The thermodynamic parameters for the interaction of metal ions with dibenzo-16-crown-5 and its derivatives have been determined by solution calorimetry in methanol at 25$^{\circ}C$. Thermodynamic properties of log K, ${\Delta}H$, and $T{\Delta}S$ have been determined for the complexation of metal cations by dibenzo-16-crown-5 and its derivatives. Dibenzo-16-crown-5 and its derivatives have been studied as metal cations carrier in bulk liquid membrane (BLM) and supported liquid membrane (SLM) system. $Ag^+$ has been much more transported using dibenzo-16-crown-5 derivatives as carriers and several other metal cations have been small transported using carrier in BLM and SLM system. Ligand structure, the length of side arm, donor atom, stability constant, and carrier concentration are also important parameters in the transport of cations.

• Journal of Life Science
• /
• v.13 no.6
• /
• pp.856-864
• /
• 2003

The 16S rRNA gene is the most common gene in the phylogenetic analysis of procaryotes. However very high conservative of 16S rRNA has limitation in the discrimination of highly related organisms, hence other molecule was applied in this study and the result was compared with that of 16S rRNA. Three COGs (Clusters of Orthologous of protein) were only detected in 42 procaryotes ; transcription elongation facto. (COG0195), bacterial DNA primase (COG0358) and uridylate kinase (COG0528). Uridylate kinase gene was selected because of the similarity and one single copy number in each genome. Bacteria, belong to same genus, and Archaebacteria were same position with high bootstrap value in phylogenetic tree like the tree of 16S rRNA. However, alpha and epsilon Proteobcteria showed different position and Spirochaetales of Eubarteria was grouped together with Archaebacteria unlike the result of 16S rRNA. Uridylate kinase may compensate the problem of very high conservative of 16S rRNA gene and it would help to access more accurate discrimination and phylogenetic analysis of bacteria.

• Health Policy and Management
• /
• v.28 no.1
• /
• pp.87-90
• /
• 2018

Suicide has been a public health issue in many countries, and Korea has ranked highest suicide rate among Organization for Economic Cooperation and Development (OECD) countries over a decade. To address these issues, we updated the recent trends in suicidal ideation and suicide attempts among Korean adults followed by previous data observation. We used data from five sources: Korean National Health and Nutrition Examination (KNHANES, '07-12, '13, '15-16), Korean Community Health Survey (KCHS, '08-09, '13), Korean Wealth Panel Study (KOWEPS, '12-16), Korea Health Panel Survey (KHP, '10-13), and cause of death data from Statistics Korea ('07-16). We used weighted frequencies and trend tests. The rate of suicidal ideation as recent year was 5.10% (KNHANES, '15), 8.95% (KCHS, '13), 2.08% (KOWEPS, '16), and 5.39% (KHP, '13). That of suicide attempts as recent year was 0.59% (KNHANES, '16), 0.41% (KCHS, '13), and 0.08% (KOWEPS, '16). Annual percentage change of suicidal ideation was -2.80% (KNHANES, '07-12), 5.78% (KNHANES, '13-15), 0.62% (KCHS, '08-13), -8.50% (KOWEPS, '12-16), and -10.94% (KHP, '10-13). Annual percentage change of suicide attempts was -3.84% (KNHANES, '07-12), 2.26% (KNHANES, '13-16), -2.53% (KCHS, '08-13), and -20.22% (KOWEPS, '12-16). Annual percentage change of death by intentional self-harm was -0.49% (Statistics Korea, '07-16). Individuals who had lower income level were more likely to experience suicidal ideation and suicide attempts. According to these results, the rate of suicidal ideation and suicide attempts showed the decreasing tendency. However, the suicide rate of Korea has remained higher than that of OECD countries. Thus, continuous data observation and effective policies on suicide are needed.