• Title/Summary/Keyword: 154

Search Result 7,010, Processing Time 0.033 seconds

Analysis of Components in the Different Parts of Lythrum salicaria L. (털부처꽃의 부위별 성분 분석)

  • Kim, Hee-Young;Park, Yea-Jin;Lee, Ju-Yeon;Kim, Ki-young;Shin, Su;Choi, Min-Woo;Hong, Eun-Jin;Kim, Min-jeong;Yeo, Sujung;Park, In-hwa;Jerng, Ui Min;An, Hyo-Jin;Cha, Yun-Yeop
    • The Korea Journal of Herbology
    • /
    • v.37 no.5
    • /
    • pp.89-96
    • /
    • 2022
  • Objectives : This research was performed to analyze the components in the different parts of Lythrum salicaria L. and to compare which parts of L. salicaria L. are appropriate for food development. Methods : L. salicaria L. was extracted in 20% EtOH at 100 ℃ for 4 hours. Cytotoxicity was investigated in 3T3-L1 cells after treatment of 10-500 ㎍/ml L. salicaria L. for 24 hours. Total polyphenol content (TPC) was estimated using 1 N Folin-ciocateu reagent. 2,2-Diphenyl-1-picryhydrazyl (DPPH) radical scavenging activity was estimated using DPPH reagent and gallic acid. The chemical composition was analyzed by high-performance liquid chromatography (HPLC). 1) Results : The half maximal inhibitory concentration (IC50) in the extracts of the whole plant, aerial parts, and root parts was 350 ㎍/ml, over 500 ㎍/ml, and 150 ㎍/ml, respectively. The TPC in the extracts of the whole plant, aerial parts, and root parts was 527.1 mg/g, 422.6 mg/g, and 781.1 mg/g, respectively. The averages of vitexin contents in the aerial parts, and root parts were 256.7 ± 154.9 ㎍/g and 266.1 ± 63.2 ㎍/g, respectively. The averages of TPC in the leaves, roots, flower stalks and stems were 224.0 ± 53.7 tannin acid (TA) mg/g, 221.8 ± 70.2 TA mg/g, 249.8 ± 34.4 TA mg/g, and 67.7±8.9 TA mg/g, respectively. The averages of DPPH radical scavenging activity in the leaves, roots, flower stalks, and stems were 282.01 ± 43.3 gallic acid equivalent (GAE) 𝜇mole/g, 260.16 ± 44.1 GAE 𝜇mole/g, 288.0 ± 9.3 GAE 𝜇mole/g, and 97.6 ± 10.7 GAE 𝜇mole/g, respectively. Conclusions : There were no significant differences in the content of components or antioxidant activity in the aerial parts compared to those in the whole plant of L. salicaria L. Furthermore, the root parts had low extract yield, cytotoxicity, and quality control problems, therefore our results suggest that the use of the aerial part of L. salicaria L. would be the most appropriate for food development.

Semantic Visualization of Dynamic Topic Modeling (다이내믹 토픽 모델링의 의미적 시각화 방법론)

  • Yeon, Jinwook;Boo, Hyunkyung;Kim, Namgyu
    • Journal of Intelligence and Information Systems
    • /
    • v.28 no.1
    • /
    • pp.131-154
    • /
    • 2022
  • Recently, researches on unstructured data analysis have been actively conducted with the development of information and communication technology. In particular, topic modeling is a representative technique for discovering core topics from massive text data. In the early stages of topic modeling, most studies focused only on topic discovery. As the topic modeling field matured, studies on the change of the topic according to the change of time began to be carried out. Accordingly, interest in dynamic topic modeling that handle changes in keywords constituting the topic is also increasing. Dynamic topic modeling identifies major topics from the data of the initial period and manages the change and flow of topics in a way that utilizes topic information of the previous period to derive further topics in subsequent periods. However, it is very difficult to understand and interpret the results of dynamic topic modeling. The results of traditional dynamic topic modeling simply reveal changes in keywords and their rankings. However, this information is insufficient to represent how the meaning of the topic has changed. Therefore, in this study, we propose a method to visualize topics by period by reflecting the meaning of keywords in each topic. In addition, we propose a method that can intuitively interpret changes in topics and relationships between or among topics. The detailed method of visualizing topics by period is as follows. In the first step, dynamic topic modeling is implemented to derive the top keywords of each period and their weight from text data. In the second step, we derive vectors of top keywords of each topic from the pre-trained word embedding model. Then, we perform dimension reduction for the extracted vectors. Then, we formulate a semantic vector of each topic by calculating weight sum of keywords in each vector using topic weight of each keyword. In the third step, we visualize the semantic vector of each topic using matplotlib, and analyze the relationship between or among the topics based on the visualized result. The change of topic can be interpreted in the following manners. From the result of dynamic topic modeling, we identify rising top 5 keywords and descending top 5 keywords for each period to show the change of the topic. Existing many topic visualization studies usually visualize keywords of each topic, but our approach proposed in this study differs from previous studies in that it attempts to visualize each topic itself. To evaluate the practical applicability of the proposed methodology, we performed an experiment on 1,847 abstracts of artificial intelligence-related papers. The experiment was performed by dividing abstracts of artificial intelligence-related papers into three periods (2016-2017, 2018-2019, 2020-2021). We selected seven topics based on the consistency score, and utilized the pre-trained word embedding model of Word2vec trained with 'Wikipedia', an Internet encyclopedia. Based on the proposed methodology, we generated a semantic vector for each topic. Through this, by reflecting the meaning of keywords, we visualized and interpreted the themes by period. Through these experiments, we confirmed that the rising and descending of the topic weight of a keyword can be usefully used to interpret the semantic change of the corresponding topic and to grasp the relationship among topics. In this study, to overcome the limitations of dynamic topic modeling results, we used word embedding and dimension reduction techniques to visualize topics by era. The results of this study are meaningful in that they broadened the scope of topic understanding through the visualization of dynamic topic modeling results. In addition, the academic contribution can be acknowledged in that it laid the foundation for follow-up studies using various word embeddings and dimensionality reduction techniques to improve the performance of the proposed methodology.

Effects of Muscle Activation Pattern and Stability of the Lower Extremity's Joint on Falls in the Elderly Walking -Retrospective Approach- (노인 보행 시 하지 근 활동 양상과 관절의 안정성이 낙상에 미치는 영향 -후향성 연구-)

  • Ryu, Jiseon
    • 한국체육학회지인문사회과학편
    • /
    • v.57 no.3
    • /
    • pp.345-356
    • /
    • 2018
  • Objective: The purpose of this study was to investigate the local stability of the lower extremity joints and muscle activation patterns of the lower extremity during walking between falling and non-falling group in the elderly women. Method: Forty women, heel strikers, were recruited for this study. Twenty subjects (age:72.55±5.42yrs; height:154.40±4.26cm; mass:57.40±6.21kg; preference walking speed:0.52±0.17m/s; fall frequency=1.70±1.26 times) had a history falls(fall group) within two years and Twenty subjects (71.90±2..90yrs; height:155.28±4.73cm; mass:56.70±5.241kg; preference walking speed: 0.56±0.13m/s) had no history falls(non-fall group). While they were walking on a instrumented treadmill at their preference speed for a long while, kinematic and EMG signals were obtained using 3-D motion capture and wireless EMG electrodes, respectively. Local stability of the ankle and knee joint were calculated using Lyapunov Exponent (LyE) and muscles activation and their co-contraction index were also quantified. Hypotheses were tested using one-way ANOVA and Mann-Whitey. Spearman rank was also used to determine the correlation coefficients between variables. Level of significance was set at p<.05. Results: Local stability in the knee joint adduction-abduction was significantly greater in fall group than non-fall group(p<.05). Activation of anterior tibials that acts on the foot segment dorsal flexion was greater in non-fall group than fall group(p<.05). CI between gastrocnemius and anterior tibials was found to be significantly different between two groups(p<.05). In addition, there was significant correlation between CI of the leg and LyE of the ankle joint flexion-extention in the fall group(p<.05). Conclusion: In conclusion, muscles that act on the knee joint abduction-adduction as well as gastrocnemius and anterior tibials that act on the ankle joint flexion-extention need to be strengthened to prevent from potential fall during walking.

An Analytical Study on Rational use of Undersea Space (해저공간의 합리적 활용을 위한 분석적 연구)

  • Won-Jo Jung;Nam-Ki Park
    • Journal of Navigation and Port Research
    • /
    • v.47 no.3
    • /
    • pp.147-154
    • /
    • 2023
  • This study aims to determine the necessity, role, utilization, and operation and management plan in relation to the underwater space platform where humans can newly reside. It provides a comprehensive opinion on the need for creating undersea space and operation plans based on opinions of industry-university-affiliated organizations involved in the R&D project of the Ministry of Maritime Affairs and Fisheries for the utilization of undersea space and external experts participating in marine technology development. In this study, a survey was conducted on researchers participating in the construction of a Korean submarine space platform. FGI was conducted on marine technology development experts. Results were then derived. As a result of the analysis, the need for subsea space construction was found to be high. As for the role of subsea space, the most common opinion was to develop technology for utilizing subsea space and to secure marine science research functions. It was found that the creation of subsea space would have a positive impact on the domestic industry, especially the deep-sea development industry and the shipbuilding/offshore structure industry. In terms of utilization, after the end of the seabed space test bed, the response to utilization as a marine observation base and marine ecosystem research had the highest proportion. As for expected inconvenience, discomfort in the psychological environment was the highest. Experts suggest that securing a continuous budget is most important for stable operation in the future and that securing a manpower budget is essential for itemized budgets. In addition, it was judged that it would be appropriate to establish a prior agreement from the time of the prior agreement and prepare a countermeasure before proceeding with the project in order to ensure ownership issues, consignment management issues, and cost issues when using the project after the end of the project.

A relationship between food environment and food insecurity in households with immigrant women residing in the Seoul metropolitan area (수도권 거주 결혼이주여성 가구의 식품환경과 식품불안정성 간의 관련성)

  • Sung-Min Yook;Ji-Yun Hwang
    • Journal of Nutrition and Health
    • /
    • v.56 no.3
    • /
    • pp.264-276
    • /
    • 2023
  • Purpose: Food environmental factors related to food insecurity affect household food intake in several socio-ecological aspects. This study explores the relationship between food environment factors and food insecurity in households with married immigrant women. Methods: From November 2018 to February 2020, a survey was conducted enrolling 249 married immigrant women residing in the metropolitan areas of South Korea. In the final analysis, 229 subjects were divided into 2 groups classified as food security (n = 154) and food insecurity (n = 75), as assessed by the score of food security. Three aspects of food environments were measured: built·natural, political·economic, and socio-cultural Results: Food environments were significantly different between food security and food insecurity groups, as follows: the number of foods market and their distance from the home and food status for the last week at home in the built·natural domain; monthly cost of food purchase and experience for food assistance in the political·economic domain; total score of social support, parenting, and cooking skills in the socio-cultural domain. A stepwise multivariate linear regression model showed a negative association between the food insecurity score with social support from family and food inventory status in the last week. After adjusting for confounders, a positive association was obtained between the experience of a food support program. The final regression model explains about 30% of the relationship obtained in the three food environment domains and food insecurity (p < 0.001). Conclusion: Not only economic factors, which are common determinants of household food insecurity, but socio-cultural factors such as social support also affect household food insecurity. Therefore, plans for implementing a food assistance program to improve food insecurity for households with immigrant women should consider financial support as well as other comprehensive aspects, including socio-cultural domain such as social support from family and community.

Studies on the Early Development of the Mouse Embryo Transplanted in the Anterior Chamber of the Eye (眼前房내에 이식한 생쥐배의 초기발생에 관한 연구)

  • Cho, Wan Kyoo;Kim, Moon Kyoo
    • The Korean Journal of Zoology
    • /
    • v.15 no.1
    • /
    • pp.25-33
    • /
    • 1972
  • Two-Cell mouse embryos were incubated in the anterior chamber of the rat eye, which has been known as the best place among other animals' for the mouse ovum maturation, in order to observe the capability of their early development. Within 120 hours after incubation, 71.0% of two-cell embryos have developed to the blastocysts in the male rat eye, while only 38.5% in the eye of the same mouse as donated two-cell embryos. Thus, the rat eye chamber provides more favourable environment to the embryos than the mouse itself. The results are consistent with those of the previous studies comparing the maturation of the mouse follicular oocytes in the mouse and the rat eye chamber. Although the aqueous humor which is filled in the anterior chamber of the eye is characterized by its specific properties, being of higher osmolarity, higher concentrations of ascorbic acid, pyruvate and lactate, but lower of proteins and lower temperature than those in blood or lymph serum, The embryos are able to under-take their cleavage as normal as in vivo or in vitro. Concerning with a number of studies in vitro on the development of the mouse embryos which are requiring a very limited condition, the fact that they are able to manage their further development under very different enviroment from our knowledges would provide us a moment to understand their behavior during the early development. The difference of the proportion of the developed blastocysts between in the mouse eye chamber and in the rat can possibly be resulted from the species specific difference in the physicochemical properties between their eye chambers. This assumption is based upon the findings by many investigators who chmpared the nature of the eye chamber of various animals. As a consequence, the rat eye chamber might consist of better properties for the embryonal growth than the mouse eye chamber. The mouse embryos cleaved with a delayed period. In normal development they complete almost the cleavage within 94 hours after fertilization. However, in the present studies, 81.1% of two-cell embryos developed to the blastocysts and the morula in 120 hours in the eye chamber, assumed to be about 154 hours after fertilization. Such delay in development would be caused mainly by the low temperature of the eye chamber. At present we can make two assumptions to explain the capability of the emtryonal development in the eye chambers. One is that the embryos would possess an ability to adapt themselves to the environment which provides unfavourable conditions. The other is that the embryos might remain for a certain duration in the eye chamber, which is filled with a new body fluid produced immediately after the loss of the aqueous humor and the fluid of which becomes similar to blood serum in component. The first assumption is highly reliable since the embryonal cells are mostly at the undifferentiated state and so they probably engage a simple metabolism during their early period. The second assumption is induced by the fact that the rabbit eye chamber produces a plasmoid humor which has mostly similar components to blood serum after loss of aqueous humor through cornea by puncturing. However, the plasmoid humor is substituted by the initial aqueous humor in eight hours. Even though this finding, production of the new fluid, could be applied to the rat eye, it is hardly reliabel that the plasmoid humor remains for such a long period as 120 hours. Consequently, the development of the embryos is more likely due to their adaptability to the new environment during their early developmental stages.

  • PDF

Interviews on Learner's Interest in Learning of Lifelong Education Center in University (대학 평생교육원 학습자의 학습흥미유발에 대한 인터뷰)

  • Kim, Young-Woo
    • Journal of Korea Entertainment Industry Association
    • /
    • v.13 no.2
    • /
    • pp.145-154
    • /
    • 2019
  • The purpose of this study is to investigate the performance, learning motivation and satisfaction of the students who take the university 's Lifelong Education Program. The research method was interviewed. The results are as follows. In terms of operations; First, the awareness of the kindness of employees of the college lifelong education institute needs to be strengthened at the beginning of the school year. Second, in the operation of the College Lifelong Education Center, the support such as the parking fee should be extended to the students. Third, lifelong education facilities should be supplemented. In terms of participation motivation; First, it can be seen that there are the most learners who want to do complementary learning. Most of them are people who look back on their lives and prepare for their future directions. Second, as the life span of human beings became longer, the economic preparation for life became necessary. Thus, all learning tends to be perceived as a preparation for economic income. Third, most people who participate in lifelong education are very interested in health. Therefore, it is necessary to increase the motivation for participation by expanding health related programs. In terms of satisfaction; First, it depends on the purpose of the individual. Satisfaction was high for those who aimed at hobbies and relationships, and satisfaction for those who aimed for economic activities was low. Second, it is also necessary to consider the instructor 's instructional process. In other words, lifelong learners tend to be adults, so little complaints are not revealed. Therefore, I would like to ask the lecturers to advance the education for the class. The implications for the improvement direction of the lifelong education center are as follows; First, we need to drastically reduce the number of programs overlapping with other universities and conduct research to develop new programs. In order to do this, it is necessary to continuously carry out a survey of demanders' needs. Second, it is necessary to find the appropriate place for program operation considering the movement distance of learners. It should be avoided that the program should be operated with the existing university facilities. Third, universities' lifelong education should go to education that includes college students.

Estimation of Representative Wave Period and Optimal Probability Density Function Using Wave Observed Data around Korean Western Coast (국내 서해안 파랑 관측자료를 이용한 대표주기 산정 및 최적 확률밀도함수 추정)

  • Uk-Jae Lee;Hong-Yeon Cho;Jin Ho Park;Dong-Hui Ko
    • Journal of Korean Society of Coastal and Ocean Engineers
    • /
    • v.35 no.6
    • /
    • pp.146-154
    • /
    • 2023
  • In this study, the peak wave period Tp and mean wave period T02 and Tm-1, 0, which are major parameters for classifying ocean characteristics, were calculated using water surface elevation data observed from the second west coast oceanographic and meteorological observation tower. In addition, the ratio of abnormal data, correlation analysis, and optimal probability density function were estimated. In the case of Tp among the calculated representative periods, the proportion of abnormal data was 5.73% and 0.67% at each point, and T02 was 4.35% and 0.01%. Tm-1, 0 was found to be 2.82% and 0.03%. Meanwhile, as a result of analyzing the relationship between T02 and Tp, the relationship was calculated to be 0.53 and 0.63 for each point. The relationship between Tm-1, 0 and Tp was 1.15 and 1.32, respectively, and T02, Tm-1, 0 was 1.18 and 1.22. As a result of estimating the optimal probability density function of the calculated representative period, Tp followed the 'Log-normal' and 'Normal' distributions at each point, and T02 was 'Gamma', 'Normal' distribution and Tm-1, 0 showed that 'Log-normal' and 'Normal' distribution were dominant, respectively. It is decided that these results can be used as basic data for wave analysis conducted on the west coast.

Quality improvement and aging effect of beef by low-temperature treatment of non-preferred parts of beef (비선호 부위 소고기의 저온처리에 의한 품질향상 및 소고기의 숙성효과)

  • Hyun Kyoung Kim;Soon Cheol Kim;Hyeon Jin Kim;Yeong Mi Kim
    • The Journal of the Convergence on Culture Technology
    • /
    • v.9 no.5
    • /
    • pp.753-760
    • /
    • 2023
  • In this study, quality improvement of beef was attempted according to the low temperature treatment and aging period of grade 1 compared to grade 1++ beef. The fat content and shear force of beef grade 1++ were 13.03% and 114.26N, but beef grade 1 was 3.21% and 149.67N. Meanwhile, after low-temperature treatment of grade 1 beef at -26℃ for 12 hours and low-temperature aging at 0 ℃ for 14 days, the shear force was greatly reduced to 87.85N, improving overall preference, softness, dripping gravy, flavor, and chewing texture. The essential free amino acid content was as low as 22.17mg/100g in grade 1++ beef, but the contents were high at 41.31~45.11mg/100g in three samples of grade 1, and there was no change in content according to cold treatment conditions. As a specific component of beef, Taurine was 30.94~34.41mg/100g, and the difference in content was small according to beef grade, but Anserine and Creatine were low at 19.68mg/100g and 70.01mg/100g in beef grade 1++ and high at 26.38~31.23mg/100g and 154.09~167.26mg/10g in beef grade 1. The content ratio of oleic acid (c18:1)/stearic acid (c18:0) as an monounsaturated fatty acid/saturated fatty acid ratio was low at 5.29 for grade 1++ beef, but high at 6.13~6.78 for grade 1 beef. In addition, there was no trend in the content ratio of these fatty acids according to the low-temperature treatment conditions and aging period in beef grade 1. As a result of this study, it was possible to improve the quality of beef grade 1 by low-temperature treatment at -26 ℃ for 12 hours and then aging at 0 ℃ for 14 days.

Production of highly enriched GABA through Lactobacillus plantarum fermentation of katsuobushi protein hydrolyzate made from Dendropanax morbiferus extract fermented by Bacillus subtilis (황칠나무 추출물의 고초균 발효물로 제조된 가쓰오부시 단백가수분해물의 Lactobacillus plantarum 발효를 통한 고농도 GABA 생산)

  • Yu-Jeong An;Nak-Ju Sung;Sam-Pin Lee
    • Food Science and Preservation
    • /
    • v.30 no.1
    • /
    • pp.146-154
    • /
    • 2023
  • To develop a multi-functional ingredient, the bioconversion of katsuobushi protein was optimized using Bacillus subtilis HA and Lactobacillus plantarum KS2020. The Dendropanax morbiferus extract (DME) culture with protease activity (102 unit/mL) was prepared by B. subtilis with 2% glucose and 1% skim milk through one day of alkaline fermentation. Katsuobushi protein was effectively hydrolyzed by the DME culture at 60℃ for 3 hours, resulting in a tyrosine content of 156.85 mg%. Subsequently, a second lactic acid fermentation was carried out with 10% monosodium glutamate (MSG) using L. plantarum KS2020 to produce higher levels of GABA. Following co-cultivation for three days, DME exhibited a pH of 8.3 (0% acidity). After seven days, the viable cell count of L. plantarum increased to 9.33 CFU/mL, but viable Bacillus cells were not detected. Taken together, a multi-functional ingredient with enriched GABA, peptides, probiotics, and umami flavor was developed through lactic acid fermentation using hydrolyzed katsuobushi protein. These results indicate that katsuobushi protein could be used as a byproduct to produce a palatable protein hydrolysate using alkaline-fermented DME culture as a proteolytic enzyme source.