• 제목/요약/키워드: 14-3-$3{\beta}$

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적도 북동 태평양, 클라리온-클리퍼톤 균열대에서 산출되는 망간단괴내의 자생 필립사이트 (Authigenic Phillipsite in Deep-sea Manganese Nodules from the Clarion-Clipperton Fracture Zones, NE Equatorial Pacific)

  • 이찬희;이성록
    • 자원환경지질
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    • 제29권4호
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    • pp.421-428
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    • 1996
  • 망간단괴내에 자생하는 필립사이트는 단괴의 핵을 이루는 풍화된 화산암편과 고화된 해저퇴적물 또는 단괴를 이루는 망간광물들의 층간에서 산출된다. 이 광물은 주로 화산성 유리질 석기들의 가상조직을 보이고 있으며, 연한 노란색을 갖는 등립질의 판상으로 산출된다. 필립사이트 입자들은 자형의 삼각능, 사각기둥 또는 도변상을 가지며 크기는 길이 $2{\sim}20{\mu}m$, 두께 $2{\sim}5{\mu}m$정도이다. 이 광물의 화학조성은 $({Ca_{0.1}Mg_{0.3}Na_{1.1}K_{1.5}})_3{(Fe_{0.3}Al_{4.2}Si_{11.8})O_{32}{\cdot}10H_2O}$이며, $Si/(Al+Fe^{+3})=2.37-2.78$, Na/K=0.59-0.81 로서 Si와 알카리의 함량이 아주 높다. 결정구조는 단사정계($P2_l/m$) 속하며 $a=10.005{\AA}$, $b=14.129{\AA}$, $c=8.686{\AA}$, ${\beta}=124.35^{\circ}$ 이고 $V=1013.6{\AA}^3$ 이다. 심해저 환경으로 보아 망간단괴에서 산출되는 필립사이트는 보통 $10^{\circ}C$ 이하의 온도, 0.7 kb 정도의 압력, pH 8 정도의 조건에서 자생하는 것으로 추정된다.

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Protein Tyrosine Phosphatase 1B inhibitory Activity of Anthraquinones and Stilbenes

  • Na, Min-Kyun;Jin, Wen Yi;Min, Byung-Sun;Ahn, Jong-Seog;Bae, Ki-Hwan
    • Natural Product Sciences
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    • 제14권2호
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    • pp.143-146
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    • 2008
  • Protein tyrosine phosphatase 1B (PTP1B) is emerging as a potential therapeutic target for the treatment of type-2 diabetes and obesity. To search for new types of PTP1B inhibitors, we have undertaken in vitro enzyme assay for some anthraquinones and stilbenes isolated from plants. Of the anthraquinones tested, physcion (1), 1-O-methylemodin (2), and emodin (3) showed high activities, with $IC_{50}$ values of 7.6, 7.0, and $3.8{\mu}g/mL$, respectively, while the anthraquinone glycosides, physcion-8-O-${\beta}$-D-glucopyranoside (4) and emodin-8- O-${\beta}$-D-glucopyranoside (5), were less active than their aglycones. All the stilbenens (6 - 15) slightly inhibited PTP1B activity at high concentration of $30{\mu}g/mL$. Our findings suggest that the hypoglycemic effect of anthraquinones may be associated with their PTP1B inhibitory activity.

임상간호사의 고위험 병원체 감염 환자 간호의도 영향요인 (Factors Influencing Clinical Nurses' Nursing Intention for High Risk Pathogen Infected Patient)

  • 김현지;최연희
    • 임상간호연구
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    • 제22권3호
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    • pp.327-335
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    • 2016
  • Purpose: The purpose of this study was to determine factors related to clinical nurses' nursing intention for high risk pathogen infected patient. Methods: The participants were 230 clinical nurses from four university hospitals which located in B and D metropolitan cities. Data were collected from September 14 to 25 in 2015 and were analyzed using a hierarchical regression. Results: The mean of nursing intention score for high risk pathogen infected patient for the participants was $110.62{\pm}12.68$ (range 36~180). The most influential factor for nursing intention was professional self concept of nurses (${\beta}=.321$), and organizational group culture (${\beta}=.166$) was the next influential factor. The level of education and working department were also statistically significant contributors. Conclusion: It is necessary to increase clinical nurses' nursing intention for high risk pathogen infected patient to improve professional self concept of nurses and organizational group culture.

Mycological Characteristics of Fusarium solani f. sp. pisi Isolated from Pea, Ginseng and Soybean in Korea

  • Jung, Yong-Sung;Kim, Young-Tae;Yoo, Sung-Joon;Kim, Hong-Gi
    • The Plant Pathology Journal
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    • 제15권1호
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    • pp.44-47
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    • 1999
  • Fungal isolates belong to Fusarium solani (perfect stage : Nectria haematococca) were isolated form pea, ginseng roots and soybean during 1995 and 1996 in Korea. Thirty-five isolates were identified as F. solani f. sp. pisi based on the morphological characteristics and their pathogenicity. Microconidia formed on the long conidiophore were ovoid or oblong sizing 5~14 x 2.5~5.0 $\mu\textrm{m}$. Macroconidia were formed on carnation leaf agar media with 4.8~5.3 x 32.0~40.7 $\mu\textrm{m}$ in size. They belonged to $\beta$-type since their 3-septate macroconidia were smaller than $5\mu\textrm{m}$ in width. Chlamydospores were smooth- or rough- walled and formed in terminal or lateral branches of hyphae, intercalary, or in chains. Most isolates were highly virulent to pea seedlings, producing dark brown or rot lesions. This is the first report of f. solani f. sp. pisi being pathogenic to pea in Korea.

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물리치료사의 직무 및 조직특성이 전문직업성에 미치는 영향에 관한 연구 (A Study on the Relation Between Physical Therapist Professionalism and Organizational and Job Characteristics)

  • 고관우;이경원;서삼기
    • The Journal of Korean Physical Therapy
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    • 제25권5호
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    • pp.343-351
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    • 2013
  • Purpose: This study was designed to measure the level of professional autonomy regarding physical therapists and to determine the association of organizational and occupational characteristics of the profession with its professional autonomy. Methods: We utilized a structured questionnaire survey of physical therapists (280 persons) in Jeju province. Data were collected from June 25 to July 14 in 2012. An additional 173 (63%) of them were used in the final analysis. Using PASW 18.0, descriptive and Hierarchical Linear Model were performed. Results: Regression analysis Result of Factors influencing Physiotherapist Professionalism, refresher training course (t=4.27), formalization (t=3.13), task significance (t=3.39), and autonomy (t=4.17) had a positive effect. Autonomy (${\beta}$=0.33) and formalization (${\beta}$=0.33) exerted the greatest influence. Conclusion: The survey regarding organizational and job characteristics showeds that occupational reeducation, formalization, and self- regulation constitute a positive part of what the professional autonomy is to be upheld. Results of the survey imply that in order to establish professional autonomy for the profession of physical therapist, the organization must make various efforts to beef up the exclusive knowledge and technology, and professional norms of the occupation that are considered essential for specific problem solving.

여대생의 바람직한 식습관과 정상체중의 유지 (Healthy Eating Habits Related to Normal Weight Maintenance among Female University Students)

  • 백설향
    • 대한지역사회영양학회지
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    • 제14권3호
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    • pp.295-305
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    • 2009
  • In order to investigate how to maintain normal weight under independent living conditions, twenty female university students were enrolled and asked to complete a questionnaire over a 10- day study period. T-test, Spearman's correlation and multiple regression analysis were applied to describe characteristics of weight maintainers' habits on a daily basis. The results were as follows: They always comsumed small or moderate-sized meals. $2{\sim}3$ co-eaters usually had dinner together at home while not watching TV. They also showed healthy eating behaviors such as no snacking, very little amounts of soft drinks, coffee and alcohol consumption. The always normal weight maintainers, however, were not physically active at all. When being with co-eater(s), they ate larger-sized dinners (${\beta}$ = 0.585, $R^2$= 30.6), and the more co-eaters they had at the dinner table, the greater BMI they got (${\beta}$ = 0.547, $R^2$= 29.9). As a result of this study, encouraging young adult people to exercise on a regular basis is required, even though they seem to succeed in maintaining normal weight without being active physically. Further study is necessary to investigate how co-eaters would influence the amount of food eaten.

재래식 메주에서 분리한 효모들의 각종 효소활성과 가능성

  • 이종수;이성훈;권수진;안철;유진영
    • 한국미생물·생명공학회지
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    • 제25권5호
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    • pp.448-453
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    • 1997
  • Enzyme activities, production of killer toxin and some functionality of forty seven yeasts isolated from traditional Meju were investigated in culture broth and cell free extracts. Activities of $\alpha$-galactosidase, invertase and inulinase were detected in cell free extracts of 38 strains, 43 strains and 45 strains, respectively and acidic and neutral protease activities also were detected in culture broth of all the strains, $\beta$-Galactosidase activity was detected in cell free extracts of OE-20 and S-14 strains. Killer toxins were produced by OE-12, S-8 (Candida spp.), OE-19 (Zygosaccharomyces spp.) and S-3 (Saccharomyces spp.). Culture broth of OE-23 and S-9 showed 61.3% and 59.2% of antioxidant activity to $\alpha$, $\alpha$-diphenyl-$\beta$-picrylhydrazyl(DPPH), but nitrite-scavenging ability as well as inhibition of tyrosinase and polyphenol oxidase were not appeared in all the strains.

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호르몬 첨가가 돼지 난포란의 체외성숙과 체외수정에 미치는 영향 (Effect of Hormones on Pig Oocytes Maturation and Fertilization In Vitro)

  • 권건오;정영채;김창근;윤종택;최선호;류범용
    • 한국가축번식학회지
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    • 제14권3호
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    • pp.223-230
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    • 1990
  • This experiment was carried out to investigate in vitro maturation rate of pig follicular oocytes cultured from 30 to 48hr in TCM 199 supplemented with gonadotropins(FSH, LH) and estradiol-17$\beta$ and in vitro fertilization with ejaculated sperm preincubated in BO medium containing 2mM caffein and development of IVF oocytes. The results obtained in this experiments were as follows ; 1. In addition of hormones, in vitro maturation rate of follicular oocyte increased gradually from 36hr and 74.47% at 48hr in addition of hormones, but there was no differences among in vitro maturation rates after 36hr of culture. 2. Penetration rate of pig oocytes matured in FSH+LH+E2 and FSH+E2 was 71.8%, 71.0% and significantly increased by the addition of hormones. 3. Percentage of developed oocytes was 44.4% for oocytes matured in FSH+LH+E2-added medium and 48.7% for oocytes matured in FSH+E2-added medium, respectively. 4. Two to 16 cells stage embryos were obtained only when pig oocytes matuerd in vitro in hormones-added medium and 72hr after IVF. 5. From present results, it is concluded that gonadotropins and estradiol17$\beta$ can enhance in vitro fertilization and subsequent development as well as in vitro maturation pig follicular oocytes.

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신갈나무 잎으로부터 분리한 페놀성 화합물의 함량분석 (Contents Analysis of phenolic compounds from the Leaves of Quercus mongolica)

  • 황인혁;;윤성혜;안혜신;왕혜수;이민원
    • 생약학회지
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    • 제48권4호
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    • pp.339-342
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    • 2017
  • Quercus mongolica (QM) is a species of Quercus native to Eastern Mongolia, Siberia, China, Japan, and Korea. QM has been used as Korean traditional medicine for the treatment of inflammation of the skin. Present work, the validation and content determination of the phenolic compounds which were isolated from the leaves of QM, including pedunculagin (1) and kaempferol-3-O-(6"-galloyl)-${\beta}$-D-glucopyranoside (2) were conducted through High-Performance Liquid Chromatography (HPLC). As a result, the contents of these compounds were 4.14% and 0.76% in QM extract, respectively.

Life Transition Process Effects on Depressive Symptoms in Parents of Children with Autism Spectrum Disorder

  • Hong, Sun Woo;Kim, JinShil;Lee, Ae Ran;Choi, Jeong Sil
    • Child Health Nursing Research
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    • 제24권3호
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    • pp.337-344
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    • 2018
  • Purpose: The purpose of this study is to examine the association between each phase of the Life Transition Process (LTP) and depressive symptoms among parents of children with Autism Spectrum Disorder (ASD). Methods: Using a cross-sectional study design, data pertaining to LTP and depressive symptoms were collected from 285 parents of children with ASD (101 fathers and 184 mothers). Participants were recruited through the Autism Society of Korea and a counseling center for families of children with ASD. Results: Using a cut-off point of 5 or higher on the Beck Depression Inventory-Short Form, more than half of the parents (53.4%) were deemed depressed; these parents experienced moderate (27.4%) to severe (11.6%) levels of depressive symptoms. A hierarchical multiple regression using the socio-demographic characteristics of children and parents and each phase of the LTP as predictors, found that lower income (${\beta}=-.14$, p=.007) and greater scores for the wandering phase (${\beta}=.59$, p<.001) were significant predictors of greater levels of depressive symptoms. Conclusion: These findings confirm the association between LTP and depressive symptoms for parents of children with ASD, who were found to have a greater risk of depressive symptoms during wandering phase.