• Title/Summary/Keyword: 14-3-$3{\beta}$

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Change of Brain Activation due to Change of Viewpoint in Action during Action Observation: an EEG Analysis Study (동작관찰 중 동작 수행 시 시점의 변화에 따른 뇌 활성의 변화)

  • Kim, Oi-Jin;Sim, Ji-Young;Lee, Se-Young;Jin, Hyun-Jin
    • PNF and Movement
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    • v.14 no.3
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    • pp.209-217
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    • 2016
  • Purpose: Treatments using a mirror neuron system, such as 3D virtual reality therapy, are used in stroke rehabilitation, but they need to be constructed according to a detailed procedure. The aims of this study were to analyze electroencephalograms (EEG) during relaxation and action while observing first person perspective (1AE) and third person perspective (3AE) videos of the right hand for 20's. Methods: Thirty participants (Male=4, Female=26) were recruited for this study. Participants were selected by a vividness of movement imagery questionnaire (VMIQ). EEG was measured during relaxxation and during action with 1AE and 3AE videos, focusing on the supination and pronation actions of participants' right hands. An absolute mu rhythm, a relatively high alpha power, and a relative beta power were identified. In each group, one-way repeated measures ANOVA was used for statistical analysis. Results: Measurement of absolute mu rhythms was significantly suppressed for both 1AE and 3AE compared with relaxation in C3 and C4 regions. High alpha wave measurements were significantly suppressed for both 1AE and 3AE in all regions, while beta wave measurements were significantly increased only for 3AE in F3 and F4 regions. Conclusion: Based on this study, we suggest that the mirror neuron system is activated during actions accompanied by action observation, especially actions with 3AE video observation, which can be a great therapeutic mathod in stroke rehabilitation.

The Crystal and Molecular Structure of 1-(Hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl) Urea: Tolazamide ($C_{14}H_{21}N_3O_3S$)

  • Koo, Chung-Hoe;Suh, Jung-Sun;Yeon, Young-Hee;Watanabe, Tokunosuke
    • Archives of Pharmacal Research
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    • v.11 no.1
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    • pp.74-79
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    • 1988
  • Crystals of tolazamide, $C_{14}H_{21}N_3O_3S$, are triclinic space group $P{\bar{1}}$ with cell dimensions of a = 6.355 (2), b = 9.223 (2), c = 13.510 (3) A, ${\alpha}\;=\;101.04\;(8),\;{\beta}=92.80(5),\;{\gamma}\;=\;85.72\;(6)^{\circ}$ and Z = 2. Intensities were collected on an automated four-circle diffractometer using graphite-monochromated Cu K ${\alpha}$ radiations. The structure was solved by direct method and refined by full-matrix least-squares to an R factor of 0.058 for 1184 observed reflections. The molecules are dimerized by the $N-H{\cdots}O$ hydrogen bonds. There are only van der Waals interactions between these molecular dimers.

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Oswestry Low Back Pain Disability Index and Related Factors in Patients with Low Back Pain (일부 요통환자들의 오스웨스터리요통장애지수 및 관련요인)

  • Yi, Seung-Ju
    • The Journal of Korean Physical Therapy
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    • v.20 no.4
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    • pp.21-28
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    • 2008
  • Purpose: We measured the Oswestry Low Back Pain Disability Index (OLBPDI) and related factors in patients with low back pain. Methods: The sample consisted of 50 patients who received physical therapy at the physical therapy units of the Andong Seoul Sintong Clinic, St. Luke Clinic, and Yeongju Seoul Sintong Clinic in Andong and Yeongju city from October, 2007, to February, 2008. The OLBPDI questionnaire was administered by 5 physical therapists as a cross-sectional study. Student's t-test and analysis of variance (ANOVA/Tukey and Scheffe) were used to analyze OLBPDI score differences. We also used nonparametric statistic analysis (Wilcoxon rank sum test, Median test). Pearson correlation analysis (Spearman correlation analysis) was used to analyze the relationship between OLBPDI and the visual analogue scale (VAS). Multiple regression analysis was performed to determine the effects of independent variables on pain scores as defined by the OLBPDI. Results: The average patient age was 37.1 years (range: 18$\sim$78 years old), and time from onset was 21.7 months (1$\sim$180). OLBPD and VAS scores were 12.70 (3.0$\sim$28.0) and 5.14 (1$\sim$8), respectively. OLBPDI scores were 14.4 in patients taking medicine and 11.57 in those who did not. There was a statistically significant relationship between OLBPDI and VAS (r=0.54, p=0.0001; r=0.55, p=0.0001 by Spearman coefficient). Gender ($\beta$=6.14, p=0.0124), age ($\beta$=-2.01, p=0.0324), weight ($\beta$=0.31, p=0.0222), time from onset ($\beta$=1.54, p=0.0044), and VAS score ($\beta$=1.59, p=0.0004) were significantly associated with OLBPD by multiple regression analysis. Conclusion: Variables associated with OLBPD were gender, age, weight, time from onset, and VAS score. Collecting information on the pain index using OLBPDI was acceptable to patients with low back pain. Further research should explore the pain index by using larger sample sizes and longer follow-up periods.

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The Influence of Job-seeking Stress, Adult Attachment and Self-assertiveness, on Depression among Korean College Students (대학생의 취업스트레스, 성인애착, 자기표현성이 우울에 미치는 영향)

  • Jeon, Hae Ok
    • The Journal of the Korea Contents Association
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    • v.14 no.7
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    • pp.312-323
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    • 2014
  • The purposes of this study were to examine effects of job-seeking stress, adult attachment, self-assertiveness on depression among Korean college students. Data were collected through self reported structured questionnaire form 239 Korean college students by convenient sampling methods from April 20 to May 30, 2013. The mean score of depression 14.38(SD=9.81) and 27.6% of the subjects were depression risk groups. A hierarchical multiple regression showed that job-seeking stress (${\beta}$=0.31, p<.001) and adult attachment (${\beta}$=0.32, p<.001) were identified as significant predictors of depression of college students after adjusting for gender, grade, living arrangement, satisfaction for major. And these variables accounted for 34% of depression (F=12.20, p<.001). Therefore, therapeutic nursing intervention should be developed to reduce job-seeking stress and to control attachment-related anxiety, avoidance as a way to regulate depression for Korean college students.

Optimization of the Channel of a Plate Heat Exchanger wits Ribs (리브가 있는 판형 열교환기 관내부 최적화)

  • 이관수;양동근
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.14 no.3
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    • pp.199-205
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    • 2002
  • In this paper, the optimum shape and arrangement of ribs in the channel of a plate heat exchanger are studied. The following dimensionless geometric parameters of ribs are selected as design variables: rib height ($H_R$), angle of attack ($\beta$), rib pitch ($P_R$), rib distance (L) and aspect ratio of rib (AR). The optimization is performed by minimizing the objective function consisting of the Nusselt number and the friction factor. The optimal values of design variables are as follows: $H_R$=0.263, $\beta$=0.290, $P_R$=3.142, L: 3.954, AR=0.342. The pressure drop and the heat transfer of the optimum model, compared to those of the reference model, are increased by 15.1% and 41.6%, respectively.

Saponins from the Stem Bark of Kalopanax pictum var. magnificum (I)

  • Park, Myung-Ja;Hahn, Dug-Ryong
    • Archives of Pharmacal Research
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    • v.14 no.1
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    • pp.7-11
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    • 1991
  • Three triterpenoid saponins were isolated from the methanol extract of the stem bark of Kalopanax pictum Nakai var. magnificum (Araliaceae). The structures of these saponins were identified as hederagenin 3-O-${\alpha}$-L-arabinopyranoside, hederagenin-3-O-${\alpha}$-L-rhamnopyranosyl$(1{\rightarrow}2)$-${\alpha}$-L-arabinopyranoside and 3-O-${\alpha}$-L-rhamnopyranosyl(1{\rightarrow}2)-${\alpha}$-L-arabinopyranosyl hederagenin 28-O-${\alpha}$-L-rhamnopyranosyl$(1{\rightarrow}4)$-${\beta}$-D-glucopyranosyl$(1{\rightarrow}6)$-${\beta}$-D-glucopyranosyl ester.

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Phytochemical Constituents of Allium victorialis var. platyphyllum

  • Woo, Kyeong Wan;Lee, Kang Ro
    • Natural Product Sciences
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    • v.19 no.3
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    • pp.221-226
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    • 2013
  • Phytochemical investigation of the 80% MeOH extract from the leaves of Allium victorialis var. platyphyllum resulted in the isolation of seventeen compounds; two terpenes, three norsesquiterpenes, one furofuran lignan, and eleven phenolic derivatives. Their chemical structures were characterized by spectroscopic methods to be trans-phytol (1), phytene-1,2-diol (2), icariside B2 (3), (6S,9S)-roseoside (4), sedumoside G (5), pinoresinol-4-O-glucoside (6), 2-methoxy-2-(4'-hydroxyphenyl)ethanol (7), 2-hydroxy-2-(4'-hydroxyphenyl)ethanol (8), Benzyl ${\beta}$-D-glucopyranoside (9), methyl ferulate (10), trans-ferulic acid (11), methyl-p-hydroxycinnamate (12), glucosyl methyl ferulate (13), linocaffein (14), siringin (15), 2-(4-hydroxy-3-methoxyphenyl)-ethyl-O-${\beta}$-Dglucopyranoside (16), and pseudolaroside C (17). All compounds were isolated for the first time from this plant.

Study on Steroid Acly Transferase in the Rat Brain (쥐 뇌의 Steroid Acyl 전이효소에 대한 연구)

  • 조도현
    • KSBB Journal
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    • v.5 no.3
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    • pp.201-205
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    • 1990
  • The characteristics of steroid acyl transferase were studied in the rat brain with (4-14C)-dehydroepiandrosterone(DHEA). The results could be summarized as followings: The enzyme system responsible for the biosynthesis was localized at the microsome fraction. The optimum pH of this enzyme was 4.6 When DHEA was utilized as substrate, $\Delta$5-pregnenolone was proved to be a competitive inhibitor. However testosterone was a noncompetitive inhibitor. The acylation at 3${\beta}$-hydroxyl group was favored when the hydrophilicity at Cl7 position increased. However, this acylation at C3 was very low when A ring was aromatic. The acylation at Cl7 hydroxyl group reguired an absolute 17${\beta}$-conformation.

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Bioactivity Guided Phytochemical Study of Clematis hirsuta Growing in Saudi Arabia

  • Abdel-Kader, Maged S.;Al-Taweel, Areej M.;El-Deeb, Kadriya S.
    • Natural Product Sciences
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    • v.14 no.1
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    • pp.56-61
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    • 2008
  • Bioactivity guided phytochemical study of the petroleum ether and butanol extracts of Clematis hirsuta resulted in the isolation of 12 compounds. Rat paw edema as a model of acute inflammation was used to evaluate the anti-inflammatory activity of the extracts and the chromatographic fractions. Five known sterols and triterpenes namely: ${\beta}-amyrin$ (1), lupeol (2), ${\beta}-sitosterol$ (3), oleanolic acid (4) and stigmasterol glycoside (5) were isolated from the petroleum ether extract. The n-butanol extract afforded two compounds reported for the first time from natural source: (S)-(+)-dihydro-5-(hydroxymethyl)-2(3H)-furanone (7) and (s)-(-)-5-hydroxymethyl-2(5H)-furanone (8). In addition, anemonin (6), dihydro-4-hydroxy-5-(hydroxymethyl)-2(3H)-furanone (2-deoxy-D-ribono-1,4-lactone) (9), biophenol (cimidahurin) (10), glucose (11) and sucrose (12) were also identified. The structures were determined from spectroscopic data including 1D- and 2D-NMR experiments.

Synthesis and Structure of N-Methylphenazinium-Tetracynnopalladate(II) Hydrate (N-Methylphenazinium-Tetracyanopalladate(II) Hydrate의 합성 및 결정구조 연구)

  • NamGung, Hae;Lee, Hyun-Mi
    • Korean Journal of Crystallography
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    • v.17 no.1
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    • pp.6-9
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    • 2006
  • Crystal structure of Bis(N-Methylphenazinium)-Tetracyanopalladate(II) hydrate has been determined by X-ray crystallography. Crystal data: $(C_{13}H_{11}N_2){_2}[Pd(cn)_4]{\cdot}H_2O$, Monocline, Space group $P2_1/b$(No=14), a=9.783(4), b=10.788(4), c=13.666(4) ${\AA},\;{\beta}=104.59(5),\;Z=2,\;V=1392.9{\AA}{^3},\;Dc=1.476gcm^{-3},\;F(000)=632,\;{\mu}=7.05cm^{-1}$. The structure was solved by Patterson method and refined by full matrix least-square methods using unit weights. The final R and S values were R=0.0257, Rw=0.0732, Rall=0.0283 and S=1.07 for 1930 observed reflections. Both cation and anion complexes are essentially planar and have dihedral angles of $10.16(4)^{\circ}$. The planar complex anions are sandwiched between slightly bent cations. The interplanar separations in one triad and between two triads are 3.419(3) and $3.402(4){\AA}$, respectively. The triads are stacked along b-axis.