• Title/Summary/Keyword: 14-3-$3{\beta}$

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Studies on Lipids of Urechis unicintus -on the Composition of Lipids, Fatty acid and Sterol- (개불의 지질에 관한 연구 -지질, 지방산 및 Sterol 조성에 관하여-)

  • JOH Yong-Goe;KIM Kyung-Sam
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.16 no.3
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    • pp.255-259
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    • 1983
  • This work was done in order to clarify the chemical characteristics, composition, fatty acid components and sterol components of the lipids from Urechis unicintus. The results obtained are summarized as follows ; 1. The lipid content, iodine value and unsaponifiable matter of the total lipids are 1.89, 111, and $14.3\%$, respectively. 2. The main components of the total lipids are phospholipids $39.8\%$, free sterol $27.7\%$ and triglyceride $21.4\%$, and two unidentified fractions are detected. 3. The main fatty acids of total lipids are $C_{20:4}(19.4\%),\;C_{16:0}(13.7\%),\;C_{20:1}(11.3\%)\;and\;C_{18:1}(10.4\%)$ 4. Sterols found are Cholesterol($57.6\%$), Brassicasterol(?)($20.3\%$), 24-methylenecholesterol ($17.7\%$),22-dehydrocholesterol($3.0\%$)and 22.trans-24-norcholesta-5,22-dien-$3{\beta}$-ol(?)$1.4\%$.

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Structure of $\alpha$,$\beta$-Diphenylsuccinic Acid ($\alpha$,$\beta$-Diphenylsuccinic Acid의 구조)

  • 서일환;윤민중
    • Korean Journal of Crystallography
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    • v.5 no.2
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    • pp.108-112
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    • 1994
  • C19H20O5, Mr=314.337, triclinic,PI, a=10.291(2)A, b=11.218(3)A, c=3.059(1)A, α=74.54(2)°, β=1148.84(1)°, r=109.84(2)°, V=883.283(2)A3, λ(Mo Kα)=0.71069A, μ=0.47 mm-1, F(000)=324, 296K, Z=2, Dx=1.18Mgm-3. Final R=0.0580 for 1637[F>3σ(F)]unique refledtions. α,β-diphenylsuccinic acid, C16H14O4, are connedted with the solvent actone by hydrogen bond O(4)-H˙˙˙O(5), forming a dimer related by related by centrosymmentry thorough intermolecualr carboxylic hydrogen bond O(1)-H˙˙˙O(2)(-x,-y,-z). The nearest distance 3.288A[O(2)˙˙˙O(2)(-x,-y,-z)] between the dimers shows that the packing of the dimer is govermed by van der Waals'force.

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Effects of Organizational Injustice on Negative Behaviors of Employees: Focusing on the Mediating Effect of Trust (조직불공정성이 조직원의 부정적 행동에 미치는 영향에 대한 연구: 신뢰의 매개효과를 중심으로)

  • Chun, Kyung Kook
    • Journal of Korean Academy of Nursing Administration
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    • v.20 no.1
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    • pp.59-68
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    • 2014
  • Purpose: The purpose of this research was to delineate the effects of organizational injustice on negative behaviors of employees with the mediating effects of trust. Methods: A survey was conducted among 550 nurses in 11 departments of 3 hospitals located in the Pohang area. Data were analyzed using frequency, descriptive statistics. correlation coefficients, regression analysis. Results: Procedural injustice (${\beta}$=-.48, p<.001) had the greatest negative effect on organizational trust, followed by interactional injustice(${\beta}$=-.15, p<.001) and distributive injustice(${\beta}$=-.14, p<.001). For supervisor trust, both procedural (${\beta}$=-.11, p=.006) and interactional (${\beta}$=-.63, p<.001) injustice had a negative effect. While supervisor trust (${\beta}$=-.28, p<.001) had greater negative effects on organizational negative behaviors of nurses compared to organizational trust (${\beta}$=-.21, p<.001), supervisor trust (${\beta}$=-.29, p<.001) had negative effects on personal negative behaviors but organizational trust had no significant effect on personal negative behaviors. Conclusion: To reduce the negative organizational behaviors of nurses, an organizational effort is needed to reduce procedural injustice by introducing fair organizational management and to reduce interactional injustice through formal or informal communication channels between supervisors and nurses.

Effect of Heparin-binding Epidermal Growth Factor (HB-EGF) on Integrin $\alpha_{\nu}-\betaFe_3$ Expression in Preimplantation Mouse Embryos

  • Lim, Jung-Jin;Shin, Hyun-Sang;Lee, Ji-Won;Kang, Sue-Man;Lee, Sung-Eun;Kang, Han-Seung;Kim, Moon-Kyoo
    • Proceedings of the Korean Society of Embryo Transfer Conference
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    • 2002.11a
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    • pp.102-102
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    • 2002
  • Heparin-bindin epidermal growth factor (HB-EGF) is one of the EGF family to be expressed at the time of implantation in the mouse uterus. Although HB-EGF has been shown to stimulate the development of embryo and uterus in the mouse, its correlation between cell adhesion molecules remains undefined. Integrin $\alpha$$_{ν}$$\beta$$_3$, one of the cell adhesion molecules, is an important mediator of cell-substratum and cell-cell adhesion in implantation. In the present studies, we investigated the effects of HB-EGF on the embryonic development, initiation of implantation and expression of integrin $\alpha$$_{ν}$$\beta$$_3$ in in vitro culture, blocking of HB-EGF, RT-PCR and immunofluores cence analysis. The results showed that HB-EGF significantly improved the developmental rate of hatched embryos (24.1%, p<0.01) and outgrowth embryos (42.5%, p<0.01). On the other hand, this growth factor showed no offset before the hatching embryonic stage. Analysis of RT-PCR showed that HB-EGF upregulated the expression level of integrina $\alpha$$_{ν}$$\beta$$_3$ subunit genes on the preimplantation embryo and outgrowth of blastocyst (120hr and 144hr after hCG injection). Immunofluorescence analysis showed that the integrin $\alpha$$_{ν}$$\beta$$_3$ subunits localized at the pericellular borders and cell-cell contact areas. Increase in fluorescence intensity was observed in the HB-EGF treated embryos. Intrauterine injection of an anti-HB-EGF antiserum at day 3 significantly decreased the number of implantation sites (14.4, p<0.01) and significantly increased the number of recovered embryos(6.4, p<0.05) at day 5. From these results, it imply that HB-EGF improve the embryo development and accelerated the expression of integrin $\alpha$$_{ν}$$\beta$$_3$ in the preimplantation mouse embryos.

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The Effects of Emotional Labor and Health Promotion Behavior on Premenstrual Syndrome in Clinical Nurses (임상간호사의 감정노동과 건강증진행위가 월경전증후군에 미치는 영향)

  • Koo, Jung Sun;Kim, Seonho
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.5
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    • pp.225-235
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    • 2018
  • This study was conducted to investigate the relationship among clinical nurses' emotional labor, health promoting behaviors and premenstrual syndrome (PMS), as well as to clarify factors that affect nurses' PMS. This was a descriptive study of 195 clinical nurses working in one university hospital and two general hospitals in the C region. Data collection was conducted from Jul 3 until Jul 21, 2017. T-test, ANOVA, Pearson's correlation coefficient and multiple regression were used for analysis. The mean score of emotional labor was $3.35{\pm}0.63$ out of 5, that of health promoting behavior was $2.08{\pm}0.40$ out of 4 and that of PMS was $2.94{\pm}1.09$ out of 6. Premenstrual syndrome was significantly positively correlated with emotional labor (r=0.292, p<0.001) and interpersonal relationships in health promotion behavior (r=0.208, p=0.004). Factors influencing PMS were interpersonal relationships (${\beta}=0.54$, p=0.001), emotional labor (${\beta}=0.40$, p=0.001) and degree of menstrual pain (${\beta}=0.14$, p<0.001), which explained 30.0% of PMS (F=9.33, p <0.001). The results of this study suggest that intervention strategies may be necessary to decrease PMS by reducing menstrual pain, emotional labor and interpersonal relationship stress.

Effect of Clinical Nurses's Basic Psychological Need, Self-Leadership and Job Stress on Nursing Performance (임상간호사의 기본심리욕구, 셀프리더십, 직무스트레스가 간호업무 성과에 미치는 영향)

  • Cho, Young-Mun;Choi, Mun-Sim
    • Journal of Digital Convergence
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    • v.14 no.8
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    • pp.343-353
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    • 2016
  • This study was done to identify variables predicting of nursing performance with basic psychological need, self-leadership and job stress in clinical nurses. The participants were 160 clinical nurses, located in P city and D province in korea. Data were collected from Feb to March, 2016 by questionnaire survey. Data analysis was done by using SPSS WIN 18.0 program with independent t-test and analysis of variance, Pearson's correlation analysis, and multiple linear regression. This study shows positive correlations between nursing performance and basic psychological needs(r=.59, p<.001), autonomy(r=.31, p<.001), competency(r=.68, p<.001), relatedness(r=.48, p<.001), self-leadership(r=.58, p<.001), job stress(r=.19, p<.05). Basic psychological needs(${\beta}$=.43), self-leadership(${\beta}$=.33), job stress(${\beta}$=.21) have a 47.3%(Adj $R^2$ .473) explanatory power for the nursing performance in clinical nurses. This study confirmed that basic psychological needs, self-leadership and job stress were identified to improve nursing performance. Therefore we should develop programs in order to increase basic psychological needs and self-leadership.

Ultimate Strength of Fillet-welded T-joints in Cold-formed Square Hollow Sections - Chord flange failure mode - (냉간성형 각형강관 모살용접 T형 접합부의 최대내력(I) - 주관 플랜지 파괴모드 -)

  • Bae, Kyu Woong;Park, Keum Sung;Kang, Chang Hoon;Moon, Tae Sup
    • Journal of Korean Society of Steel Construction
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    • v.14 no.2
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    • pp.311-318
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    • 2002
  • This paper described the ultimate strength and deformation limit of welded T-joints in cold-formed square hollow sections. Previous studies showed that the strength of a T-joint still increases with increasing deformations at a ratio of branch width to chord width (${\beta}$) of below 0.8. Therefore, the strength at a certain deformation (chord flange indentation) limit can be regarded as the ultimate strength of a T-joint. The chord flange failure modes were investigated for the ratio of branch width to chord width (${\beta}$) and the ratio of chord width to chord web thickness (B/T). Experimental results including tests done by Kato proposed a deformation limit of 3%B for $16.7{\leq}B/T{\leq}41.6$ and $0.27{\leq}{\beta}{\leq}0.8$. The strength formula of CIDECT and other researchers were compared with the test results. Finally, the strength formula based on yield-line theory was proposed.

Ultimate Strength of Fillet-welded T-joints in Cold-formed Square Hollow Sections-chord web failure mode (냉간성형 각형강관 모살용접 T형 접합부의 최대내력(II)-주관웨브 파괴모드-)

  • Bae, Kyu Woong;Park, Keum Sung;Kang, Chang Hoon;Moon, Tae Sup
    • Journal of Korean Society of Steel Construction
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    • v.14 no.3
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    • pp.403-411
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    • 2002
  • This paper described the ultimate strength and deformation limit of welded T-joints in cold-formed square hollow sections. Previous studies showed that the T-joint has an obvious peak load. with the failure mode of chord-web buckling at a ratio of branch width to chord width ($\beta$) of above 0.8. Similar to a T-joint with chord-flange failure mode, the strength at a certain deformation limit can be regarded as the ultimate strength of a T-joint Based on the experimental results including tests done by Kato and Zhao, the deformation limit was proposed as 3%B for $10.7{\leq}2{\gamma}(B/T){\leq}42.3$ and $0.8{\leq}{\beta}{\leq}1.0$. The strength formula of CIDECT and those of other researchers were also compared with the test results. Finally, the strength formula based on the column buckling was proposed.

Microstructure and Mechanical Properties of β-SiAlON Ceramics Fabricated Using Self-Propagating High-Temperature Synthesized β-SiAlON Powder

  • Kim, Min-Sung;Go, Shin-Il;Kim, Jin-Myung;Park, Young-Jo;Kim, Ha-Neul;Ko, Jae-Woong;Yun, Jon-Do
    • Journal of the Korean Ceramic Society
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    • v.54 no.4
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    • pp.292-297
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    • 2017
  • ${\beta}-SiAlON$, based on its high fracture toughness, good strength and low abrasion resistance, has been adopted in several industrial fields such as bearings, turbine blades and non-ferrous metal refractories. In general, ${\beta}-SiAlON$ is fabricated by reactive sintering using expensive $Si_3N_4$ and AlN as starting materials. On the other hand, in this study, a cheaper ${\beta}-SiAlON$ starting powder synthesized by SHS was employed to improve price competitiveness compared to that of the reactive sintering process. ${\beta}-SiAlON$ ceramics with various content of the sintering additive $Y_2O_3$ up to 7 wt% were fabricated by conventional pressureless sintering at $1800^{\circ}C$ for 2 to 8 h under $N_2$ pressure of 0.1 MPa. The specimen with 3 wt% $Y_2O_3$ exhibited the best mechanical properties: hardness of 14 GPa, biaxial strength of 830 MPa, fracture toughness of $5MPa{\cdot}m^{1/2}$ and wear rate of about $3{\times}10^{-6}mm^3/N{\cdot}m$.

Age-Dependent Progesterone Metabolism in the Rat Brain (쥐 뇌의 progesterone대사에 미치는 연령의 효과)

  • Han, Beom-Ku;Park, In-Ho;Jo, Do-Hyun
    • Applied Biological Chemistry
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    • v.38 no.1
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    • pp.37-41
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    • 1995
  • The effect of age on the metabolism of progesterone was studied in the rat brain. Metabolic activity was more active in minced tissues than total homogenates. The activity of progesterone $5{\alpha}-reductase(s)$ was increased during postnatal periods(between 5 and 14 days after birth) and thereafter steadily decreased up to the one-fourth level of the fetus. When $5{\alpha}-dihydroprogesterone$ was incubated with brain tissues of various ages, the change in the activity of $3{\alpha}-hydroxysteroid$ oxidoreductase$(3{\alpha}-HSOR)$ was similar to that of $5{\alpha}-reductase(s)$. These results suggest that the reduced formation of total $5{\alpha}-reduced$metabolites was due to the decreased activities of $5{\alpha}-reductase(s)$ and $3{\alpha}-HSOR$. However the level of $3{\beta}-HSOR$ remained constant regardless of the age.

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