• 한국정보통신학회논문지
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• 제13권7호
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• pp.1475-1482
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• 2009

본 논문에서는 최적의 Lab-on-a-Chip을 설계하기 위해 나선형 마이크로 채널에서 등속영동 프로틴 분리를 수행하는 컴퓨터 시뮬레이션을 이차원 유한 요소법을 이용하여 개발하였다. 개발한 이차원 ITP 모델은 다섯 가지 요소로 구성되며 Leader로서 염산을, Terminator로서 카르로산, 두 개의 프로틴 중 프로틴 A는 아세트산, 프로틴 B는 벤조산, 그리고 BE(Background Electrolyte)로서 히스티딘을 사용하였다. 컴퓨터 모델은 다섯 가지 구성 요소들에 대한 질량 보존 방정식과 전위에 대한 전하 보존 방정식, 그리고 pH 계산은 전기적 중성 조건식에 기반하고 있다. 제안된 이차원 공간 ITP 모델의 검증을 위해 제안한 모델의 결과와 Bohuslav Gas 그룹에서 개발한 Simu 5의 결과를 비교하였다. 시뮬레이션 결과 일차원 채널에서 두 모델이 매우 유사한 일치를 보임으로 제안한 모델의 정확성을 검증해 주었다. 이차원 프로틴 분리는 Lab-on-a-Chip 설계를 위한 이차원 곡선 채널에서 수행되어 채널 형상이 프로틴 포커싱분포(dispersions)의 변화를 초래함을 알 수 있었다.

• Design & Manufacturing
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• 제13권2호
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• pp.1-5
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• 2019

In this study, micro cellular injection molding of automobile head lamp housing with uneven thickness structure was performed to obtain improvement on deformation and light-weight of the part. The thickness of the presented model was uniformly modified to control the deformation of the molded part. In order to maximize the lightweight ratio, the model having an average thickness of 2.0 mm were thinly molded to an average thickness of 1.6 mm. GFM(Gas Free Molding) and CBM(Core Back Molding) technology were applied to improve the problems of the conventional foam molding method. Equal Heat & Cool system was also applied by 3D cooling core and individual flow control system. Warpage of the molded parts with even cooling was minimized. To improve the mechanical properties of foamed products, complex resin containing nano-filler was used and variation of mechanical properties was evaluated. It was shown that the weight reduction ratio of products with light-weighted injection molding was 8.9 % and the deformation of the products was improved from the maximum of 3.6 mm to 2.0 mm by applying Equal Heat & Cool mold cooling system. Also the mechanical strength reduction of foamed product was less than 12% at maximum.

• 분석과학
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• 제13권2호
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• pp.158-165
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• 2000

배연탈황설비에서 생성된 석고 슬러리 및 석고의 순도와 불순물의 정량분석은 시운전중인 탈황설비의 성능시험시 최적의 탈황공정을 모색하는 데 유용한 자료를 제공할 뿐만 아니라 생성된 석고는 시멘트나 석고 보드 등으로 사용될 수 있으므로 품질관리의 측면에서도 매우 중요하다. 석고의 순도는 결합수분, 삼산황 및 칼슘이온의 농도를 측정한 다음 환산식에 의해서 gypsum($CaSO_4{\cdot}2H_2O$)의 형태로 변환할 수 있다. 성능시험시 시료의 수가 상당히 많으므로, 좀 더 간편하면서도 정확한 분석방법의 확립을 위해 여러가지 비교실험을 실시한 결과, 열분석을 통하여 결합수분을 측정하는 방법이 1시간 이내에 분석이 완료된다는 장점 외에 재현성 또한 아주 우수하였다. 그 외 실리카를 포함한 각종 석고의 불순물의 분석은 산으로 처리하는 방법과 융제를 사용한 용융법을 비교한 결과, 용융법이 훨씬 간편하고 정확한 결과를 나타내었다. 한편 소량의 탄산 마그네슘과 탄산 칼슘의 정량을 위해 사용되는 이산화탄소 측정장치의 트랩부분을 수정하여 이산화탄소 흡수제의 역류를 막도록 하였다. 열분석을 통한 결함수분 측정, 융제를 사용한 용융법 및 이산화탄소의 정량법으로 확립된 분석 방법을 통해 석고 슬러리 및 석고의 분석은 보다 짧은 시간내에 간편하면서도 정확하게 실시될 수 있음을 확인하였다.

• 한국재료학회지
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• 제13권4호
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• pp.266-270
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• 2003

We studied BCl$_3$ dry etching of GaAs in a planar inductively coupled plasma system. The investigated process parameters were planar ICP source power, chamber pressure, RIE chuck power and gas flow rate. The ICP source power was varied from 0 to 500 W. Chamber pressure, RIE chuck power and gas flow rate were controlled from 5 to 15 mTorr, 0 to 150 W and 10 to 40 sccm, respectively. We found that a process condition at 20 sccm $BCl_3$ 300 W ICP, 100 W RIE and 7.5 mTorr chamber pressure gave an excellent etch result. The etched GaAs feature depicted extremely smooth surface (RMS roughness < 1 nm), vertical sidewall, relatively fast etch rate (> $3000\AA$/min) and good selectivity to a photoresist (> 3 : 1). XPS study indicated a very clean surface of the material after dry etching of GaAs. We also noticed that our planar ICP source was successfully ignited both with and without RIE chuck power, which was generally not the case with a typical cylindrical ICP source, where assistance of RIE chuck power was required for turning on a plasma and maintaining it. It demonstrated that the planar ICP source could be a very versatile tool for advanced dry etching of damage-sensitive compound semiconductors.

• 한국과학교육학회지
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• 제17권3호
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• pp.313-321
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• 1997

The purpose of this study was to investigate the instructional effect of a four-stage problem solving approach visually emphasizing the molecular level of matter upon students' conceptions and problem solving ability. On the basis of the research results regarding molecular representation in learning chemistry, problem-solving instruction, and the effect of visual materials, the instructional strategy was developed while considering Korean educational situations. The treatment and control groups (2 classes) were selected from a girls' high school in Seoul and taught about stoichiometry, gas, liquid, solid, and solution for 13 weeks. For the treatment group, 52 charts were supplied in order to emphasize the molecular level of matter and/or 4 stage problem solving strategy-understanding, planning, solving, and reviewing. For the control group, traditional instruction was used. Before the instructions, the Group Assessment of Logical Thinking and the Spatial Ability Test were administered, and their scores were used as covariate and blocking variable, respectively. After the instructions, students' conceptions and problem solving ability were measured by the Chemistry Conceptions Test (CCT) and the Chemistry Problem Solving Ability Test (CPSAT), respectively. The results indicated that the CCT scores of the treatment group were significantly higher than those of the control group. The students in the treatment group also exhibited less misconceptions than those in the control group. However, there was not significant difference for the CPSAT scores. No interaction with students' spatial ability was found for both students' conceptions and problem solving ability. Educational implications are discussed.

• 한국태양에너지학회 논문집
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• 제27권3호
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• pp.7-13
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• 2007

A Dish type solar concentrating system consists of a parabolic concentrator and a cavity receiver. In order to achieve high temperatures from solar energy, it is essential to efficiently reflect the solar rays in the concentrator and to minimize thermal losses in the cavity receiver. Improving the economical efficiency of a solar power system required the stirling unit to be operated continuously. For continuous operation of the stilting unit, the receiver must be continuously provided with thermal energy from solar as well as additional combustion heat. It is possible for a hybrid solar receiver system equipped with an additional combustion to be operated 24 hrs/day. A hybrid solar receiver was designed and manufactured for a total thermal load of 35 kW in the operating temperature range $700^{\circ}C$ to $800^{\circ}C$. The hybrid receiver system was tested in gas-only mode by gas-fired heat to investigate thermal characteristics at inclination angle varying from 0 deg to 30 deg(cavity facing down) and the aperture to cavity diameter ratios of 0(closed cavity) and 1.0(open cavity). This paper has been conducted to measure temperature distribution in cavity surface and to analyze thermal resistances, and the evaporation and condensation heat transfer coefficient in all cases(open and closed cavity).

• 기본간호학회지
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• 제5권1호
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• pp.125-141
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• 1998

The purpose of this research is to analyze the effects of aerobic exercise on body composition, cardiopulmonary function, serum lipid level and antioxidants of obese and normal college female students. The subject group was made up of 13 normal students (below 30% body fat ratio) and 12 obese students (above 30% body fat ratio). After a pretest, the subjects were given an 8-week aerobic program. Then the subjects were given a posttest and analyzed of body composition, serum lipid level, antioxidants and cardiopulmonary function after the 6th and the 8th week of the program. The program schedule was made up of 4 days per week, 60 minutes per day. Test includes B.W., subscapular and triceps subcutaneous fat thickness, change of respiratory gas, and two blood sampling before treadmill exercise and post all out state, which analyzed serum lipid and antioxidants. The subjects performed treadmill exercise starting with 4km/hr of walking and then gradually increase the speed of 1km/hr per minute until all out state. The obtained data were analyzed using SAS program. The statistical methods employed here were one-way ANOVA with repeated measure, Duncan Multiple range test, paired-t test and t-test. The test results and conclusion of this research were as follows. 1. The effects of aerobic exercise on body composition were as follows ; Percent body fat was significantly reduced 6 weeks after the program and lean body mass was significantly increased 8 weeks after the program in both groups(obese group: F=3.44 P=.044, normal group: F=3.30 P=.048). subscapular skinfold of the obese group showed a remarkable decrease after the 6th week(F=4.33 P=.021) triceps skinfold of the normal group showed a remarkable decrease after the 6th and the 8th week(F=4.55 P=.017) compared with readings before the aerobic program, the aerobic program made a bigger difference concerning body fat, lean body mass, subscapular skinfold in the obese group than in the normal group(t=2.41 P=.024, t=2.40 p=.025, t=2.43 p=.028). 2. The effects of aerobic exercise on cardiopulmonary function were as follows ; Maximal $O_2$ uptake/kg was significantly increased 6 weeks after the program in the obese group(F=3.20 P=.054), but not much difference was observed in the normal group. Maximal pulse rate was significantly reduced in both groups after 6 weeks of the program(obese group: F=2.77 P=.087, normal group: F=7.17 P=.001). 3. The effects of aerobic exercise on serum lipid level were as follows ; In a resting period, total cholesterol, Triglyceride, and LDL-cholesterol were slightly higher in the obese group than in the normal group, but HDL-cholesterol was higher in the normal group. But, with the aerobic program, total-cholesterol, Triglyceride, LDL-cholesterol were reduced gradually and HDL-choleterol got increased in both groups, but not much change was noticed in the normal group. However, in the obese group, serum HDL-cholesterol level got increased significantly(F=5.12 P=.012). 4. The effects of aerobic exercise in serum antioxidants were as follows ; In a resting period, the obese group's serum Free Radical and GSSG content were higher than the normal group's and the normal group's serum GSH content was higher than the obese group's. After 6 weeks of the aerobic program, Free Radical was reduced significantly in both groups(obese group: F=13.87 P=.000, normal group: F=18.60 P=.000) In the obese group, 8 weeks after the program, GSH was increased significantly(F=13.78, P=.000). In the normal group, 6 weeks after the program, GSH was reduced but increased again after 8 weeks(F=6.07 P=.005). Plasma GSSG was significantly increased after 8 weeks of exercise in both groups(obese group: F=19.75 P=.000, normal group: F=22.42 P=.000,) Compared with readings before the aerobic program, the aerobic program made a bigger difference serum GSH in the normal group than in the obese group(t=3.37 p=.003). As this result shows, it is known that the regular aerobic exercise improves cardiopulmonary function, body composition, serum lipid effectively and through the serum Free Radical reduction and antioxidant system activation, oxidant stress was suppressed. This effect was higher in the obese group than in the normal one. At least 6weeks exercise period need for improvement of body composition, cardiopulmonary function and activation of antioxidant system. This result suggest that improvement of serum lipid profile was needed longer than 8weeks exercise period.

• Asian Pacific Journal of Cancer Prevention
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• 제14권8호
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• pp.4829-4834
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• 2013

Background: Breast self examination (BSE), performed regularly every month, is one of the most important methods in the early diagnosis of breast cancer. This study was performed with the aim of establishing the knowledge, attitudes, and behavior of women working in government hospitals within the province of Samsun regarding BSE. Materials and Methods: This cross-sectional study was conducted between January-March 2012, on a total of 550 women (500 health personnel, and 50 general administration services (GAS) workers) from 7 government hospitals and the Cancer Early Diagnosis, Screening, and Education Centre (CEDSEC). Percentages were used for the descriptive statistics, and the chi-square test for the evaluation of statistical importance. Values of p<0.05 were accepted as significant. Results: The mean age of the participants was $36.2{\pm}15.3$, and 42.5% were in the 30-39 year old age group, 78.0% being married. Seventy-eight point four percent (78.4%) of the health personnel and 76.0% of the GAS workers performed BSE. However, the rates of performing BSE regularly every month were only 25.6% and 5.0%. Within the health personnel, 1.4% stated that they did not perform BSE because they found it unnecessary as they had no history of breast cancer in their family, 3.6% did not do so due to fear and stress, 13.2% because they forgot, and 14.6% because they had no complaints. Some 22.2% of the health personnel and 52.0% of the GAS workers had undergone mammographic evaluation, the difference being significant (p<0.05), 84.1% of the health personnel and 61.9% of the GAS workers knowing symptoms of breast cancer. Conclusions: Women in society should be brought to a certain level of awareness and knowledge regarding BSE. It is of the utmost importance that health personnel, who carry the responsibility for counseling and enlightening society, should interiorize the necessary knowledge, attitudes and behavior.

• Advances in pediatric surgery
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• 제17권2호
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• pp.179-187
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• 2011

Experimental tracheal ligation (TL) has been shown to reverse the pulmonary hypoplasia associated with congenital diaphragmatic hernia (CDH) and to normalize gas exchange. The purpose of this study was to determine whether the TL would correct the surfactant deficiency present in the fetal rabbit model of CDH by using lamellar body count. Lamellar bodies are synthesized and secreted by the type II pneumocytes of fetal lung. The phospholipids present in these bodies constitute the major component of pulmonary surfactant. Twenty-one pregnant New Zealand rabbits underwent hysterotomy and fetal surgery on gestational day 24. Two fetuses of each pregnant rabbit were operated. In the fetus of one end of bicornuate uterus, left DH was created by excision of fetal diaphragm through open thoracotomy (DH Group). In the fetus of the other end of bicornuate uterus, left DH and TL were created (TL Group). The fetuses were delivered by Cesarean section on gestational day 31. Fourteen in control group, 12 in the DH group and 13 in TL group were born alive. En bloc excision of lungs, bronchi and trachea was done in all newborn rabbits. A five Fr catheter was inserted through trachea and repeated irrigations with 10 cc normal saline were done. The irrigated fluid was centrifuged at $280{\times}g$ for 5 minutes and the lamellar bodies were counted with the upper level fluid in platelet channel of electronic cell counter. The average lamellar body counts were $37.1{\pm}14.2{\times}10^3/{\mu}L$ in control group, $11.5{\pm}4.4 {\times}10^3/{\mu}L$ in DH group, and $6.5{\pm}0.9{\times}10^3/{\mu}L$ in TL group. Lamellar body count in DH group was lower than in control group and did not increase after TL. This study shows TL has no therapeutic effect on decreased surfactant level of CDH and the pregnant rabbit is appropriate for the animal model of CDH.

• Asian-Australasian Journal of Animal Sciences
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• 제12권8호
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• pp.1215-1221
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• 1999

Twelve rumen fistulated cross-bred calves were divided into three groups and fed wheat straw and concentrate mixture according to their maintenance requirement. Animals in group II and III were fed 50 and 100mg rumensin per day, in addition to basal feed. Supplementation of rumensin in the diet decreased the dry matter intake significantly (p<0.05) along with a significant decrease in the straw intake. Digestibility coefficients of all the nutrients were not affected significantly except that of CF digestibility which was lower (p<0.05) in groups II and III as compared to group I. Among N-parameters in the rumen fluid, mean $NH_3-N$ was significantly lower in groups II and III (19.13 and 18.63 mg N/100 ml respectively) than in group I (22.68); total-N and TCA-ppt-N did not differ among the three groups. Total VFA concentration did also not differ among the three groups, however, propionate increased from 24.33 molar % to 32.73 while acetate and butyrate decreased respectively from 65.85 to 58.81% and 9.79 to 8.46%. Total VFA, bacteria and protozoa production rates were not affected significantly due to rumensin in diet. Methane production per kg DDM as well as % of methane in total gas were reduced at both the levels of rumensin on different concentrate ratios with wheat straw as roughage. Similar trend was also observed with rice straw and concentrate mixture as substrate with rumensin addition.