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Hot melt extruded-based nano zinc as an alternative to the pharmacological dose of ZnO in weanling piglets

  • Oh, Seung Min;Kim, Min Ju;Hosseindoust, Abdolreza;Kim, Kwang Yeol;Choi, Yo Han;Ham, Hyung Bin;Hwang, Sung Jun;Lee, Jun Hyung;Cho, Hyun Jong;Kang, Wei Soo;Chae, Byung Jo
    • Asian-Australasian Journal of Animal Sciences
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    • v.33 no.6
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    • pp.992-1001
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    • 2020
  • Objective: This study was conducted to investigate the effects of hot-melt extruded ZnO nano-particles (HME-ZnO) as an alternative for P-ZnO on growth performance, nutrient digestibility, Zn bioavailability, intestinal microbiota, and intestinal morphology of weanling pigs. Methods: A total of 450 piglets (Landrace×Yorkshire×Duroc) were randomly allotted to five treatments based on initial body weight and sex. The experimental diets were fed in a meal form as phase 1 from d 0 to 14 and phase 2 from d 15 to 28. Treatments were the control diet without ZnO supplementation, the diet containing 2,500 ppm Zn as ZnO, and three diets containing 500, 1,000, or 2,500 ppm Zn as HME-ZnO. Results: The overall result showed a higher (p<0.01) average daily gain in weanling pigs fed ZnO-supplemented diets in comparison to the control diet. There was a decrease (p<0.01) in fecal score in the ZnO-supplemented diets. Dietary supplementation of ZnO improved (p<0.05) crude protein digestibility. The weanling pigs fed the P-ZnO diet had a lower (p<0.01) Zn digestibility in the feces than HME-ZnO supplemented treatments. Weanling pigs fed diets supplemented with ZnO had greater (p<0.05) Lactobacillus spp. populations and lower Clostridium spp. (p<0.05) and Coliforms (p<0.01) populations in the ileum. Weanling pigs fed diets supplemented with increasing concentrations of HME-ZnO linearly decreased Clostridium spp. (p<0.05) and Coliforms (p<0.01) in the ileum. Lower (p<0.05) Clostridium spp. and Coliforms counts in the colon were observed in pigs fed with ZnO-supplemented diets. Weanling pigs fed diets supplemented with ZnO showed a greater (p<0.01) villus height in the duodenum. Conclusion: Dietary supplementation of HME-ZnO and P-ZnO showed a potential to improve the digestibility of protein, intestinal Coliform and Clostridium, villus height in duodenum and ileum. Moreover, HME-ZnO showed a higher Zn digestibility compared with P-ZnO.

Point Symbols on Tourist Maps: Cognitive Characteristics with Levels of Symbolization and Preference (관광지도 점기호의 상징수준과 선호도에 나타난 인지특성 연구)

  • Shim, Hye-Kyoung;Jung, In-Chul
    • Journal of the Korean Geographical Society
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    • v.43 no.6
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    • pp.981-1001
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    • 2008
  • This research deals with cognitive characteristics of point symbols on the current tourist maps in terms of the communication theory in considering levels of symbolization and those of preference. The levels of symbolization are examined on the basis of the meaning of point symbols between map-makers and map-users. Preferences of point symbols are investigated by the tourist objects. As a result, when point symbols are expressed in conciseness, the meaning and interpretation about those symbols are highly accorded. And the point symbols that have familiarity by visual experience are preferred. Also, the higher symbolical levels symbols have, the more likely they are preferred. Through that fact, familiarity from the visual experience, conciseness in expression, concreteness of figures expressed in maps, and representativeness of visualized properties were deduced as factors that affect preferences. Those factors work to affect preference complicatedly, but familiarity is prior to simplicity in preferences. Likewise, ways that visualize information, contents that are expressed as images and familiarity in terms of cognitive characteristics make a relative difference in preferences and the levels of symbolization. On the basis of those cognitive characteristics, visual complexity and ambiguity should be removed and the higher symbolical level of point symbols for efficiency of map-reading should be developed.

Quality Monitoring for Domestic Distributing Engine Oil (국내 유통 엔진오일 품질 모니터링)

  • Lim, Young-Kwan;Lee, Eun-Yul;Lee, Kyoung-Mook;Na, Yong-Gyu;Kim, Jong-Ryeol
    • Applied Chemistry for Engineering
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    • v.29 no.3
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    • pp.289-297
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    • 2018
  • The vehicle lubricant has captured 35% of the total lubricant market while the engine oil possessed 77% of the vehicle lubricant market in Korea. The suitable quality management of circulating engine oil is thus required for the driver and engine protection. But, KS and synthetic engine oil products (containing over 30% synthetic oil) are exempt to any quality inspections under Petroleum and Alternative Fuel Business Act. In this study, our research group investigated the quality monitoring of 30 kinds of domestic distributing synthetic engine oils. Two kinds of the engine oil showed an off specification from the test results; one engine oil is an imported and the other is a KS synthetic one. Also, the pattern of engine oils were analyzed using SIMDIST (simulated distillation) and the most engine oils had a broad carbon number spectrum, which is a typical of mineral oils except several imported products. Thus, we concluded that relevant laws for the proper quality management of synthetic oils and KS products are needed to be established for preventing consumer's damages.

Anti-arthritic Properties of ShinEumHur-Herbal Acupuncture Assessed by Knee Circumference, Squeak Threshold and Weight Distribution Ratio in Rats (흰쥐의 adjuvant-induced knee arthritis에 대한 신음허 약침의 치료효과)

  • Kim Gun-Ho;Hahm Dae-Hyun;Lee Han-Chang;Yeom Mijung;Han Dong-Oh;Zhao Mei Ai;Shim Insop;Kim Jang-Hyun;Lee Hye-Jung
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.18 no.4
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    • pp.1001-1006
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    • 2004
  • In order to examine the anti-arthritic properties of ShinEumHur(SEH)-herbal acupuncture, an adjuvant-induced arthritic rat was generated by the intra-articular injection of dried cells of Mycobacterium tuberculosis emulsified in squalene into the right knee joint. Fifty microliter of SEH extract was injected into Zusanli(ST36) acupoint on the ipsilateral hind paw every other day for 2 weeks. The body weight, knee circumference, squeak threshold, and weight distribution ratio were analyzed as the assessment methods addressing arthritic symptoms such as arthritic pain, edema, and tenderness. The weight distribution ratio was measured by a digital-type analgesia instrument using the dual channel scale that separately measures the weight the arthritic rat distributes to each hind paw, and thus quantifies both of swelling and pain severities at once. The therapeutic effects of SEH-herbal acupuncture, assessed by squeaking threshold and weight distribution ratio, were observed on 8th day after the arthritis induction as compared to saline group and control group. On 10th day, SEH-herbal acupuncture therapy significantly started to alleviate the growing pattern of knee circumference of an arthritic rat in the range of 0.2㎝. However, the loss of body weight was not significantly recovered. Taken together, the SEH-herbal acupuncture exhibited the significant therapeutic efficiency to treat adjuvant-induced monoarthritis in rat.

The Decision of Pyeunghwa Dam's Discharge Rate Considering Hwachun Dam Stage (화천댐수위를 고려한 평화의 댐 방류량 산정방법)

  • Lee, Eul-Rae;Yoo, Yang-Soo;Park, Myung-Ky
    • Proceedings of the Korea Water Resources Association Conference
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    • 2005.05b
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    • pp.1001-1005
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    • 2005
  • 현재 평화의 댐 배수터널은 직경 10m 원형 x 4 련의 콘크리트 라이닝 터널로 구성되어 있다. 배수터널내의 흐름특성은 터널직경, 모양, 터널결사, 조도계수 및 입구부와 출구부의 기하학적 성질, 터널의 상류수위와 하류수위 등에 따라 개수로 혹은 관수로의 흐름특성이 나타난다. 따라서 터널내의 흐름은 각각의 경우에 따른 수리학적 해석이 달리 적용되어진다. 화천댐의 수위와 연계하여 평화의 댐 방류량을 산정하기 위해서는 상$\cdot$하류 수위에 따른 관로내의 흐름특성이 다양하게 변화하는 바 이에 따른 수리학적 검토가 필요하게 된다. 본 연구에서는 배수터널의 흐름별로 계산 방법을 도출하였으며 상$\cdot$하류의 수위와 단면형태를 고려하여 먼저 배수터널내의 흐름특성을 규명한 다음 그에 합당한 유량산정공식으로 배수터널 내에서 유하하는 흐름의 유량값을 산정할 수 있는 방법을 제시하였다. 본 검토에서 구축된 계산절차에 의해서 평화의 댐 수위가 급격하게 변화하는 시점인 2002년 1월, 6월 그리고 2004년 8월 시점의 평화의 댐, 화천댐의 수위를 검토하여 방류량을 산정하였다. 평화의 댐에서는 방류량을 결정하기 위한 계측시설이 없기 때문에 가장 가까운 하류부의 화천댐 유입량과 비교를 수행하게 된다. 강우가 지속되면서 화천댐의 유입량이 증가를 하게 되는데 화천댐 유역의 국지적인 호우에 따른 유입량으로 판단되는 부분을 제외하고는 화천댐 유입량과 계산된 평화의 댐 방류량에서 유사한 결과를 도출하고 있었다. 이와 같은 산정법을 바탕으로 하여 강우에 따른 평화의 댐 방류량을 정확히 산정함으로서 댐유역의 비상사태 발생 또는 임남댐의 방류 등을 추정하는데 크게 기여할 수 있을것으로 판단된다.2$으로 나타났다. 밸브 개폐도가 $100\%$일 때가 밸브를 $60\%$$80\%$ 개폐시켰을 때보다 $0.3kg/cm^2,\;0.29kg/cm^2$ 낮게 나타나 밸브를 전체 개방 했을 때 관로내의 수압이 상수설계기준에 적합한 수압을 유지함을 알 수 있다. 상수관로 설계 기준에서는 관로내 수압을 $1.5\~4.0kg/cm^2$으로 나타내고 있는데 $6kg/cm^2$보다 과수압을 나타내는 경우가 $100\%$로 밸브를 개방하였을 때보다 $60\%,\;80\%$ 개방하였을 때가 더 빈번히 발생하고 있으므로 대상지역의 밸브 개폐는 $100\%$ 개방하는 것이 선계기준에 적합한 것으로 나타났다. 밸브 개폐에 따른 수압 변화를 모의한 결과 밸브 개폐도를 적절히 유지하여 필요수량의 확보 및 누수방지대책에 활용할 수 있을 것으로 판단된다.8R(mm)(r^2=0.84)$로 지수적으로 증가하는 경향을 나타내었다. 유거수량은 토성별로 양토를 1.0으로 기준할 때 사양토가 0.86으로 가장 작았고, 식양토 1.09, 식토 1.15로 평가되어 침투수에 비해 토성별 차이가 크게 나타났다. 이는 토성이 세립질일 수록 유거수의 저항이 작기 때문으로 생각된다. 경사에 따라서는 경사도가 증가할수록 증가하였으며 $10\% 경사일 때를 기준으로 $Ro(mm)=Ro_{10}{\times}0.797{\times}e^{-0.021s(\%)}$로 나타났다.천성 승모판 폐쇄 부전등을 초래하는 심각한 선천성 심질환이다. 그러

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Cavernous Angioma : Natural History and Management Strategies (해면상 혈관종의 자연 경과와 치료 전략)

  • Lim, Hyo Joo;Kwon, Yang;Ahn, Jae Sung;Kim, Jeong Hoon;Kim, Chang Jin;Lee, Jung Kyo;Kwun, Byung Duk
    • Journal of Korean Neurosurgical Society
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    • v.29 no.8
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    • pp.1001-1007
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    • 2000
  • Objective : We analysed diverse clinical features of the cavernous angioma. Also, we report the experience in differ-ent methods of the management and their results. Method : Data from 80 patients who were confirmed pathologically or diagnosed radiologically between Jan. 1990 and Sept. 1998 at our hospital were analysed. Variable factors that were examined were : clinical features, effects of treatment, and complications. Results : There were 47 male and 33 female patients. The age at the first presentation was from 3 to 57(mean 34.1) years old. Clinical features were seizure in 28 cases(38%), bleeding in 24 cases(32%), neurologic deficits in 12 cases(16%), headache in 10 cases(14%), and six incidental cases. The locations of lesion were cerebral and cerebellar hemisphere in 45 cases(56.2%), brainstem, basal ganglia, and thalamus in 32 cases(40%), multiple in 3 cases (3.8%). Seizure was common at the third decade and occurred frequently with the cavernous angioma in temporal (43%) or frontal lobe(39%). Bleeding was frequent after the third decade with peak at the fourth decade and had high incidence in brainstem or thalamus. The gamma-knife radiosurgery was done in 47 cases. Rebleeding occurred in 3 cases, but it was within postradiosurgery 1 year. Symptomatic radiation change occurred in 2 cases of 8 radiation change on MRI. On follow-up MRI, no evidence of rebleeding was found in 30 cases. Also, The lesion size was decreased in 3 cases. Resection was performed in 23 cases ; total 20, subtotal 2, partial 1. Postoperative complication occurred in 6 cases(26.1%). After surgery, 7(63.6%) of 11 seizure patients had outcome of seizure-free. Subclinical rebleeding occurred in one of two subtotal resected cases. In 11 patients, conservative management was done. There was neither rebleeding nor symptom aggravation during follow-up period of mean 17.2 months. Conclusion : The solution for prevention of rebleeding is complete removal of the lesion located at noneloquent area or accessible region, especially for the patients who presented symptoms or intractable seizure. However, the Gamma knife radiosurgery is considered when the lesions are located at eloquent area or when severe postoperative morbidity is expected.

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The Chemical Components of Korean Rice Germ (국산 쌀배아의 이화학적 성분)

  • Choi, One-Kyun;Yun, Seung-Kil;Hwang, Seong-Yun
    • Journal of the Korean Society of Food Culture
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    • v.15 no.4
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    • pp.253-258
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    • 2000
  • The chemical components of Korean rice germ were analyzed. Proximate compositions of rice germ were as follows; crude lipid 21.18%, crude protein 16.50%, crude fiber 2.95%, crude ash 6.23% and carbohydrate 44.45%. Free sugar compositions were as follows; fructose 50.20mg/100g, glucose 68.80mg/100g, maltose 569.00mg/100g. Major amino acids of rice germ are glutamic acid (1920.9mg/100g), arginine (1503.7mg/100g), aspartic acid(1208.7mg/100g) and leucine (1039.7mg/100g). Fatty acid compositions of rice germ lipid extracted by chloroform-methanol (2:1) were palmitic (22.2%), linoleic acid (38.9%), oleic acid (24.7%) and palmitic acid (22.2%). Mineral elements were phosphorus (1766.22mg/100g) and potassium (1217.80mg/100g). Vitamins were composed of Vit E (11.96mg/100g) Vit B1 (5.69mg/100g) and niacin (2.96mg/100g). 16 flavonoids and 9 phenolic acids in rice germ were not detected. Above the chemical components of rice germ were compared with that of rice endosperm and wheat germ.

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Removal Behavior of Biological Nitrogen and Phosphorus and Prediction of Microbial Community Composition with Its Function, in an Anaerobic-Anoxic System form Weak Sewage

  • LEE, JIN WOO;EUI SO CHOI;KYUNG IK GIL;HAN WOONG LEE;SANG HYON LEE;SOO YOOUN LEE;YONG KEUN PARK
    • Journal of Microbiology and Biotechnology
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    • v.11 no.6
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    • pp.994-1001
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    • 2001
  • An easier way of understanding the BNR system was proposed from the study on substrate, nutrient removal tendency, microbial community and its metabolic function by applying the municipal settled sewage. During the anaerobic period, the phosphorus release rate per VFACOD we varied depending on the phosphorus content in the sludge. When the phosphorus content in the sludge was $6\%$ VSS, according to influent VFACOD, the phosphorus release rate and PHA production were $0.35 gPO_4P/gVFACOD$ and 1.0 gPHA/gVFACOD, respectively. The $NO_3N$ requirement for the phosphorus uptake as an electron acceptor was about $0.5 gNO_3N/gPO_4P_{uptake}$ based on the proposed equation with PHA, biomass, production, and the concentration of phosphorus release/uptake. Bacterial-community analysis of the sludge, as determined by FISH and 16SrDNA characterization FISH, revealed that the beta-subclass proteobacteria were the most abundant group ($27.9\%$ of the proteobacteria-specific probe EUB338), and it was likely that representative of the beta-subclass played key roles in activated sludge. The next dominant group found was the gamma-protebacteria ($15.4\%$ of probe EUB338). 16S rDNA clone library analysis showed that the members of${\beta}$- and ${\gamma}$-proteobacteria were also the most abundant groups, and $21.5\%$ (PN2 and PN4) and $15.4\%$ (PN1 and PN5) of total clones were the genera of denitrifying bacteria and PAO, respectively. Prediction of the microbial community composition was made with phosphorus content (Pv, $\%$ P/VSS) in wasted sludge and profiles of COD, PHA, $PO_4P,\;and\;NO_3N$ in an anaerobic-anoxic SBR unit. Generally, the predicted microbial composition based upon metabolic function, i.e., as measured by stoichiometry, is fairly similar to that measure by the unculturable dependent method. In this study, a proposal was made on he microbial community composition that was more easily approached to analyze the reactor behavior.

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Combined Effects of High Pressure and Heat on Shear Value and Histological Characteristics of Bovine Skeletal Muscle

  • Rusman, H.;Gerelt, B.;Yamamoto, S.;Nishiumi, T.;Suzuki, A.
    • Asian-Australasian Journal of Animal Sciences
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    • v.20 no.6
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    • pp.994-1001
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    • 2007
  • Changes in shear force value, transverse sections, myofibrils and intramuscular connective tissue of bovine skeletal muscle exposed to the combination of high-pressure up to 400 MPa and heat (30 and $60^{\circ}C$) were studied. The shear force value decreased by pressure-heat treatment up to 200 MPa at 30 and $60^{\circ}C$, and then slightly increased over 200 MPa at $30^{\circ}C$. Shear force values of treated muscles were lower than those of untreated ones. Gaps between muscle fibers in the untreated muscle were a little clear, and then they became very clear in the treated muscles up to 200 MPa at 30 and $60^{\circ}C$. However, the gaps reduced significantly over 200 MPa at $30^{\circ}C$. The remarkable rupture of I-band and loss of M-line materials progressed in the myofibrils with increasing pressure applied. However, degradation and loss of the Z-line in myofibrils observed in the muscle treated at $60^{\circ}C$ was not apparent in the muscle treated at $30^{\circ}C$. The length of the sarcomere initially contracted by pressure-heat treatment of 100 MPa at $30^{\circ}C$ seemed to have recovered with increase of the pressure up to 400 MPa. In the muscle treated at $60^{\circ}C$, the length of sarcomere gradually decreased with increase of the pressure up to 400 MPa. In the treated muscles, changes in the honeycomb-like structure of endomysium were observed and accelerated with increase of the pressure. A wavy appearance clearly observed at the inside surface of endomysium in the untreated muscles gradually decreased in the treated muscles with increase of the pressure. Tearing of the membrane was observed in the muscles treated over 150 MPa at $30^{\circ}C$, as observed in the sample pressurized at 100 MPa at $60^{\circ}C$. The roughening, disruption and fraying of the membrane were observed over 200 MPa at $60^{\circ}C$. From the results obtained, the combination of high-pressure and heat treatments seems to be effective to tenderize tough meat. The shear force value may have some relationship with deformation of intramuscular connective tissue and myofibrils.

Effects of Operating Variables on Sorption Capacity of CO2 Absorbents for SEWGS Process (SEWGS 공정용 CO2 흡수제들의 흡수능력에 미치는 조업변수들의 영향)

  • Ryu, Ho-Jung;Kim, Hyo-Sung;Lee, Seung-Yong;Lee, Dong-Ho;Kim, Jae-Chang
    • Korean Chemical Engineering Research
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    • v.50 no.6
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    • pp.994-1001
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    • 2012
  • The Effects of operating variables on reactivity of two $CO_2$ absorbents (PKM1-SU and P4-600) for SEWGS process were investigated in a pressurized fluidized bed reactor. For both $CO_2$ absorbents, $CO_2$ sorption capacity decreased as the number of absorption-regeneration cycles increased. PKM1-SU absorbent represented higher $CO_2$ sorption capacity than that of P4-600 absorbent. However, P4-600 absorbent represented better performance than PKM1-SU absorbent from the view points of regeneration temperature and regeneration rate. For PKM1-SU absorbent, $CO_2$ sorption capacity increased as the steam concentration increased. However, $CO_2$ sorption capacity increased initially as the steam concentration increased from 5% to 10%, but maintained thereafter for P4-600 absorbent. For both $CO_2$ absorbents, $CO_2$ sorption capacity increased as the final regeneration temperature increased. For PKM1-SU absorbent, $CO_2$ sorption capacity increased as the pressure increased and the increment tendency was drastic at higher pressure than 15 bar.