• Journal of Environmental Health Sciences
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• v.43 no.1
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• pp.71-76
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• 2017

Objectives: This study aimed to assess the environmental factors that affect particulate matters (PM10) and to compare with outdoor PM10 concentrations in an underground subway stations. Methods: The PM10 level was determined from May 2013 to September 2013 in the Seoul subway stations in four lines. PM mini-vol portable sampler sampler was used to collect PM10 for 6 hrs. Arithmetic means of PM10 concentrations with standard deviation (SD) were calculated. Paired t-test was used to compare the differences between indoor PM10 and outdoor PM10 concentrations with correlation analysis which was used to identify the association between indoor PM10 concentrations and environmental factors. Results: There were no different PM10 concentrations significantly between line 1, 2, 3 and 4 in an underground subway stations. Passenger number was positively associated with PM10 concentration while construction year was negatively associated with PM10 concentrations. Indoor PM10 concentrations were significantly higher than those in outdoor PM10 concentrations. PM10 concentrations were higher in the stations which were constructed before 1990s rather than the stations constructed after 1990s. Conclusion: PM10 levels in the underground subway stations varied greatly depending on the construction year. Therefore, it might need to be more careful management to the stations which constructed in before 1990s.

• Journal of Korean Society for Atmospheric Environment
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• v.33 no.3
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• pp.251-264
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• 2017

Recently, Jeollabuk-do has been reported as a province where the $PM_{10}$concentration is one of the highest levels in South Korea. To explore the characteristics and origins of the $PM_{10}$in Jeollabuk-do, we present one of the first long-term datasets including a statistical analysis of $PM_{10}$concentrations obtained from six cities in the province from 2010 to 2015. During the entire periods, the mean hourly $PM_{10}$concentration was $49.3{\mu}g/m^3$, which correspond to the annual ambient air quality standards for $PM_{10}$in South Korea, and the annual $PM_{10}$concentration of each city showed a similarity in year-to-year variations. In the monthly variation of $PM_{10}$, the $PM_{10}$concentrations showed a maximum value in May that was one of the top levels among the provinces of Korea while the concentrations were dramatically decreased in August showing one of the lowest levels among the provinces in Korea. For the diurnal variation of $PM_{10}$, the $PM_{10}$concentration was enhanced during the rush hours together with gaseous species of $NO_2$, and CO. When the high concentrations of $PM_{10}$were observed (the highest 10% of the $PM_{10}$mass contribution), temperature and relative humidity were low. Using HYSPLIT backward trajectories and cluster analysis for the high $PM_{10}$concentrations, we found that the pollution plumes were transported mainly from China.

• Journal of Food Hygiene and Safety
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• v.14 no.4
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• pp.433-435
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• 1999

The number of viable microorganism in drinking water was monitored according to storage temperature and storage period. The number of general bacteria in underground water was 10$^2$~10$^{5}$ CFU/ml and that of coliform group was decreased after 7days. The number of general bacteria in bottle water was increased until 7days but decreased after that day. Coliform group in bottle water were detected only 1 sample. The number of general bacteria in purified water was 10$^3$~10$^4$CFU/ml and 10$^2$~10$^4$CFU/m1 at 8$^{\circ}C$ and $25^{\circ}C$, respectively. Coliform group were not detected in purified water.

• Journal of Yeungnam Medical Science
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• v.15 no.1
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• pp.47-54
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• 1998

Interleukin-10(IL-10) inhibits production of a wide range of cytokines in various cell types and transcriptionally inhibits lipopolysaccharide (LPS)-induced expression of proinflammatory mediators. Cytokine expression by macrophages is an important aspect to ochestrate inflammatory responses. As an approach to identify mechanistic targets of IL-10, it was examined the time course for expression of KC(murine homologue of Gro) gene in murine peritoneal macrophages stimulated with LPS with or without IL-10. The effect of IL-10 on LPS induced KC mRNA expression was delayed and only seen after 1 hour treatment. Pretreatment with IL-10 did not eliminate the delayed inhibitory response nor increase the magnitude of suppression. These effects did not depend upon time of IL-10 treatment but the time of LPS treatment. LPS-induced KC mRNA expression by inhibitory action of IL-10 was not controlled at the level of transcription. The result indicates that IL-10 acts late in the process of KC gene expression and that the prominant site of action may be mRNA stability or translation.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.33 no.4
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• pp.375-379
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• 1988

To identify the evidence in tolerance to oxyfluorfen between selected rice cultivars (cv. Chokoto as the tolerant and cv. Weld Pally as the susceptible), the differences in ehtylene evolution, chlorophyll contents and electro-conductivity as affected by various concentrations of oxyfluorfen were assessed. -Under 10$^{-5}$ M oxyfluorfen, the susceptible cultivar showed rapid and higher rate of ethylene evolution, and under 10$^{-4}$ M oxyfluorfen, less difference in ethylene evolution between both cultivars. -Upto 10$^{-6}$ M oxyfluorfen, no difference in chlorophyll contents of both cultivars, however, at 10$^{-5}$ ~10$^{-4}$ M, the susceptible showed as less chlorophyll contents as half of the tolerant. At 10$^{-3}$ M, both cultivars showed complete decomposition of chlorophyll. -At 10$^{-4}$ ~10$^{-3}$ M oxyfluorfen. both cultivars indicate the increased rate in electro-conductivity, and the susceptible cultivar released as much electrolytes as 10% of the tolerant.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2001.11b
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• pp.43-48
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• 2001

This study was investigated to find out the optimum planting densities of Scutellaria baicalensis GEORGE about growth characters, yield components and yield at 3 planting densities by direct sowing cultivated after barley Stem length was long In dense planting of 20$\times$10cm and short in spacious planting of 30$\times$10cm and 40$\times$10cm by direct sowing cultivated after barley. Stem diameter was thick in spacious planting of 30$\times$10cm and 40$\times$10cm and was thin in dense planting of 20$\times$cm by direct sewing cultivated after barley. Length and dry weight of root per plant were decreased in dense planting of 20$\times$10cm and were increased in spacious planting of 30$\times$10cm and 40$\times$10cm by direct sowing cultivated after barley. Yield of dry root was highest in optimum planting density(30$\times$10cm:33 plants/$m^2$) by direct sowing cultivated after barley. The correlation coefficient between number of planting plant and stem length showed highly positive correlation. These characters of stem diameter, number of branches, main root length and yield of dry root mentioned above showed negative correlations with planting plants.

• Journal of Life Science
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• v.19 no.7
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• pp.859-865
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• 2009

Microtubules, a major cytoskeleton, form parallel arrays in the axon and are oriented with their plus ends toward the cell periphery. Kinesin superfamily proteins (KIFs) are the molecular motors acting in the microtubule-based motilities of organelles in cells. Here, we used the yeast two-hybrid system to identify the protein that interacts with the coiled-coil domain of KIF1A and found a specific interaction with microtubule-destabilizing factor SCG10. SCG10 bound to the amino acid residues between 400 and 820 of KIF1A, but not to other KIFs in the yeast two-hybrid assay. The coiled-coil domain of SCG10 is essential for interaction with KIF1A. In addition, this specific interaction was also observed in the Glutathione S-transferase pull-down assay. An antibody to SCG10 specifically co-immunoprecipitated KIF1A associated with SCG10 from mouse brain extracts. These results suggest that KIF1A motor protein transports SCG10-containing vesicles along microtubules in neurons.

• International conference on construction engineering and project management
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• 2022.06a
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• pp.128-135
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• 2022

Because construction work is conducted outdoors, construction workers are affected by harmful environmental factor. Especially, Particulate Matter (PM₁₀) is one of the harmful environmental factors with a diameter of 10㎍/m³ or less. When PM₁₀ is inhaled by human, it can cause fatal impact on the human. Contrary to the various analyses of health impact on PM₁₀, the research on the relationship between construction accidents and PM₁₀ are few. Therefore, this study aims to conduct the relative frequency analysis which find out the correlation between construction accidents and PM₁₀, and the modified PM₁₀ grade is suggested to expect accidents probability caused by PM₁₀ in the construction industry. This study is conducted by four steps. i) Establishment of the database; ii) Classification of data; iii) Analysis of the Relative Frequency of accidents in the construction industry by PM₁₀ concentration; iv) Modified PM₁₀ groups to classify the impact of PM₁₀ on accident. In terms of frequency analysis, the most accidents were occurred in the average concentration of PM₁₀ (32㎍/m³). However, we found that the relative frequency of accident was increased as the concentration of PM₁₀ increased. This means the higher PM₁₀ concentration can cause more accidents during construction. In addition, PM₁₀ concentration was divided as 6 groups by the WHO, but the modified PM₁₀ grade by the relative frequency on accident was suggested as 3 groups.

• Korean Journal of Veterinary Research
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• v.37 no.2
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• pp.331-338
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• 1997

최근 동물의 진통 및 진정을 목적으로 널리 사용되고 있는 imidazole 유도체인 clonidine, medetomidine, etomidate 등의 약물과 xylazine의 효과를 발정정지기의 척출 돼지 자궁근에서 검토하였다. Clonidine($10^{-8}{\sim}10^{-6}M$)이나 medetomidine($10^{-8}{\sim}10^{-6}M$)은 xylazine과 비슷한 정도로 용량의존적인 자궁근의 수축을 일으켰다. Clonidine, medetomidine, xylazine 등의 $EC_{50}$는 각각 24.7nM, 19.9nM, 45.1nM이었다. 그러나 etomidate는 $10^{-6}M$ 미만의 농도에서 반응이 거의 없었으며, $10^{-6}M$ 이상에서 수축반응을 일으켰다. 이들 agonists의 효과는 yohimbine($10^{-8}{\sim}10^{-6}M$), idazoxan($10^{-7}{\sim}10^{-5}M$), tolazoline($10^{-7}{\sim}10^{-5}M$) 등의 ${\alpha}_2-adrenoceptor$ antagonists에 의해서 차단되었으나, ${\alpha}_1-adrenoceptor$ antagonist인 prazosin ($10^{-6}M$)에 의해서는 차단되지 않았다. 또한 $Ca^{2+}-free$ medium이나 verapamil($10^{-5}M$)의 전처치에 의해서 이들 agonist의 효과가 완전히 차단되었다. 결론적으로 발정정지기의 돼지 자궁근에서 clonidine, medetomidine, etomidate, xylazine 등은 ${\alpha}_2-adrenoceptors$의 흥분을 통해 자궁근의 수축을 일으키며, 이 효과는 voltage-dependent $Ca^{2+}$ channels을 통한 extracellular $Ca^{2+}$ influx의 증가에 의한 것으로 추론하였다.

• The Korean Journal of Pharmacology
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• v.30 no.2
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• pp.181-190
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• 1994

In rat atrium the characteristics of purinergic receptors were investigated by observing the effects of some purinergic receptor agonists and antagonists on action potential and contractile force. The statistically significant effects of $ATP(10^{-6}{\sim}10^{-3}M)$ and adenosine $(10^{-6}{\sim}10^{-3}M)$ on normal action potential characteristics were a dose-dependent shortening of action potential duration $(APD_{90})$ by both agents and hyperpolarization by $ATP(10^{-4},10^{-3}M)$. $CAP(10^{-8}{\sim}10^{-4}M)$, an $A_1$ adenosine receptor agonist, shortened $(APD_{90})$ markedly in a dose-dependent manner and these effects were almost abolished by $DPCPX\;(10^{-6}\;M), an $A_1$, adenosine receptor antagonist, but not affected by $DMPX(2{\times}10^{-6}\;M)$, an $A_2$ adenosine receptor agonist. On the other hand, CGS $21680(10^{-7}{\sim}10^{-4}M)$, an $A_2$ adenosine receptor agonist, elicited a slight shortening of $(APD_{90})$ and these effects were inhibited by DPCPX but persisted in the presence of DPMX. Adenosine $(10^{-6}{\sim}10{\-4}\;M)$ decreased the basal contraction of atrial muscle in a dose-dependent manner and these effects were not inhibited by DMPX but by DPCPX. These results suggests that purinergic receptor agonists depress the cardiac activity by a short ening of action potential duration and this effect is mostly mediated by $A_1$ adenosine receptors in rat atrium.