• Journal of the Earthquake Engineering Society of Korea
• /
• v.19 no.3
• /
• pp.85-92
• /
• 2015

Response spectra of a building are made with a SDOF system taking into account a first mode shape, even though higher modes may affect on the dynamic responses of a high-rise building. A soft soil layer under a building also affects on the responses of a building. In this study, seismic responses of a MDOF system were investigated to examine the effects of higher modes on the response of a tall building by comparing them with those of a SDOF system including the kinematic interaction effect. Study was performed using a pseudo 3D finite element program with seven bedrock earthquake records downloaded from the PEER database. Effects of higher modes on the seismic responses of a tall building were investigated for base shear force and base moment of a MDOF system including story shear forces and story moments. Study results show that higher modes of a MDOF system contribute to a reduction of base shear force up to 1/4-1/5 of KBC and base moment. The effect of higher modes is more significant on the base shear force than on the base moment. Maximum story shear force and moment occurred at the top part of a building rather than at a base in the cases of tall buildings differently from short buildings, and higher modes of a tall building affected on the base forces making them almost constant at the base. A soft soil layer also affects some on the base shear force of a high-rise building independently on the soft soil type, but a soft soil effect is prominent on the base moment.

• Korean Journal of Applied Biomechanics
• /
• v.13 no.1
• /
• pp.13-21
• /
• 2003

The purpose of this study is (a) to estimate effective moment arms of quadriceps forces and (b) to compare the $d_e$ between the ACL-reconstructed and uninjured knees from the same individual. One female (20 yrs old, 2 yrs post-op, hamstring tendon autograft) and two males (22 yrs old, 2 yrs post-op; 28 yrs old, 4 yrs post-op; Patellar tendon autografts for both). Sagittal view radiographs were obtained for 6-7 different angles $(range\;5^{\circ}-110^{\circ})$ from each knee. The do was determined by the method of Chow et al. (1999a). The results showed that the maximum de values ranged from 4.61 to 5.59cm and 4.59 to 4.89cm for the ACL-reconstructed and uninjured knees, respectively. The maximum $d_e$ occurred between $35^{\circ}\;and\;50^{\circ}\;and\;20^{\circ}\;and\;50^{\circ}$ for the ACL-reconstructed and uninjured knees, respectively. The minimum do values ranged from 4.12 to 4.35 cm and 3.12 to 3.63cm for the ACL-reconstructed and uninjured knees, respectively. The effective moment arm of the knee extensor affects the loads on knee ligaments during knee-extension exercises. Because apparent differences in the moment arm of the quadriceps in different participants, it is very important to use personalized knee joint geometry for the computation of knee joint force. In the present study, no noticeable bilateral difference was found in the male subjects. However, apparent bilateral differences in de were observed in the female subject. This suggests that the effects of ACL reconstruction surgery on patellar mechanism deserve further investigation.

• Steel and Composite Structures
• /
• v.52 no.1
• /
• pp.31-43
• /
• 2024

A very widely used analytical method (mathematical model), mentioned in Eurocode 3, to examine the connections' bending behavior is the component-based method that has certain weak points shown in the plastic behavior part of the moment-rotation curves. In the component method available in Eurocode 3, for simplicity, the effect of strain hardening is omitted, and the bending behavior of the connection is modeled with the help of a two-line diagram. To make the component method more efficient and reliable, this research proposed its advanced version, wherein the plastic part of the diagram was developed beyond the guidelines of the mentioned Regulation, implemented to connect the end plate, and verified with the moment-rotation curves found from the laboratory model and the finite element method in ABAQUS. The findings indicated that the advanced component method (the method developed in this research) could predict the plastic part of the moment-rotation curve as well as the conventional component-based method in Eurocode 3. The comparison between the laboratory model and the outputs of the conventional and advanced component methods, as well as the outputs of the finite elements approach using ABAQUS, revealed a different percentage in the ultimate moment for bolt-extended end-plate connections. Specifically, the difference percentages were -31.56%, 2.46%, and 9.84%, respectively. Another aim of this research was to determine the optimal dimensions of the end plate joint to reduce costs without letting the mechanical constraints related to the bending moment and the resulting initial stiffness, are not compromised as well as the safety and integrity of the connection. In this research, the thickness and dimensions of the end plate and the location and diameter of the bolts were the design variables, which were optimized using Particle Swarm Optimization (PSO), Snake Optimization (SO), and Teaching Learning-Based Optimization (TLBO) to minimization the connection cost of the end plate connection. According to the results, the TLBO method yielded better solutions than others, reducing the connection costs from 43.97 to 17.45€ (60.3%), which shows the method's proper efficiency.

• Journal of the Society of Cosmetic Scientists of Korea
• /
• v.40 no.4
• /
• pp.383-390
• /
• 2014

The following conclusion was made from the 2D-QSAR model for the tyrosinase inhibitory activity according to the variation of the substituents R1 and R2 in analogues of compound 2-[(2,6-dioxocyclohexyl)methyl]cyclohexane- 1,3-dione (1-23). The best optimized 2D-QSAR model was $Obs.pI_{50}=-0.295({\pm}0.031)TDM$ $-0.120({\pm}0.014)DMZ+0.135({\pm}0.050)DMX.R_2+6.382({\pm}0.17)$, and the correlation $r^2=0.905$) of which was greater than its predictability ($q^2=0.843$). The magnitude of the effect of tyrosinase inhibitory activities was in order of TDM > $DMX.R_2{\geq}DMZ$, and it tended to increase as the hydrophobicity of substrate molecule (ClogP > 0) as well as the steric favor of substituent $R_1$ increased. The analysis of the model implies that inhibitory activity of substrate molecule will increase as $DMX.R_2$ (Dipole moment X component of $R_2$-substituent) increases, while TDM (Total Dipole Moment) and DMZ(Dipole Moment of Z-Component) decrease. As such, it is deemed feasible to conclude, that in order to increase the inhibitory effect, it would be rather desirable to replace the polar groups within the molecules with non-polar functional groups.

• Journal of the Korea institute for structural maintenance and inspection
• /
• v.22 no.1
• /
• pp.107-114
• /
• 2018

In this study, the damage detection method is proposed for the rotational stiffness of connections in steel moment frames by using artificial neural network(ANN). The flexural moment of columns, natural frequencies, modeshapes are used for the input layer in ANN while the damage index, that signify the damage level, is used for the output layer in ANN. The 5-story steel moment frame as an example structure is used to generate the train and test data. Total number of damage scenarios considered is 829. From the results of application, it is shown that the proposed method can accurately estimate the location and level of damages.

• Journal of the Korea Concrete Institute
• /
• v.21 no.1
• /
• pp.93-103
• /
• 2009

The concept of the effective moment of inertia has been generally used for the deflection estimation of reinforced concrete flexural members. The KCI design code adopted Branson's equation for simple calculation of deflection, in which a representative value of the effective moment of inertia is used for the whole length of a member. However, the code equation for the effective moment of inertia was formulated based on the results of beam tests subjected to uniformly distributed loads, which may not effectively account for those of members under different loading conditions. Therefore, this study aimed to verify the influences of moment shapes resulting from different loading patterns by experiments. Six beams were fabricated and tested in this study, where primary variables were concrete compressive strengths and loading distances from supports, and test results were compared to the code equation and other existing approaches. A method utilizing variational analysis for the deflection estimation has been also proposed, which accounts for the influences of moment shapes to the effective moment of inertia. The test results indicated that the effective moment of inertia was somewhat influenced by the moment shape, and that this influence of moment shape to the effective moment of inertia was not captured by the code equation. Compared to the code equation, the proposed method had smaller variation in the ratios of the test results to the estimated values of beam deflections. Therefore, the proposed method is considered to be a good approach to take into account the influence of moment shape for the estimation of beam deflection, however, the differences between test results and estimated deflections show that more researches are still required to improve its accuracy by modifying the shape function of deflection.

• Korean Journal of Environmental Biology
• /
• v.24 no.1 s.61
• /
• pp.46-52
• /
• 2006

The mercury is among the most highly bioconcentrated toxic trace metals. Many national and international agencies and organisations have targeted mercury for the possible emission control. The mercury toxicity depends on its chemical form, among which alkylmercury compounds are the most toxic. A human cervix uterus cancer cell line HeLa cells was employed to investigate the effect of the toxic heavy metal mercury (Hg) and ionizing radiation. In the in vitro comet assays for the genotoxicity in the HeLa cells, the group of Hg treatment after irradiation showed higher DNA breakage than the other groups. The tail extent moment and olive tail moment of the control group were $4.88{\pm}1.00\;and\;3.50{\pm}0.52$ while the values of the only Hg treatment group were $26.90{\pm}2.67\;and\;13.16{\pm}1.82$, respectively. The tail extent moment and olive tail moment of the only 0.001, 0.005, 0.01 Hg group were $12.24{\pm}1.82,\;8.20{\pm}2.15,\;20.30{\pm}1.30,\;12.26{\pm}0.52,\;40.65{\pm}2.94\;and \;20.38{\pm}1.49$, respectively. In the case of Hg treatment after irradiation, the tail extent moment and olive tail moment of the 0.001, 0.005, 0.01 Hg group were $56.50{\pm}3.93,\;32.69{\pm}2.48,\;62.03{\pm}5.14,\;31.56{\pm}1.97,\;72.73{\pm}3.70\;and \;39.44{\pm}3.23$, respectively. The results showed that Hg induced DNA single-strand breaks or alkali labile sites as assessed by the Comet assay. It is in good agreement with the reported results. The mercury inhibits the repair of DNA. The bacterial formamidopyrimidine-DNA glycosylase (Epg protein) recognizes and removes some oxidative DNA base modifications. Enzyme inactivation by Hg (II) may therefore be due either to interactions with rysteine residues outside the metal binding domain or to very high-affinity binding of Hg (II) which readily removes Zn (II) from the zinc finger.

• Journal of Korean Society of Steel Construction
• /
• v.17 no.1 s.74
• /
• pp.83-92
• /
• 2005

This paper is to evaluate the load carrying capacities of cold-formed steel columns subject to combined axial load and bending moment. A combined strength experiment is carried out using full-scale 24 specimens of lipped channel section with embossment in web. An eccentric axial load is applied in varying member-length and eccentric distance which produces an end-moment of the column. The predictions of the AISI specification and the Eurocode are compared with the experimental results, and it is shown that all of these codes are reasonable on the whole in relation to the experimental results.

• Proceedings of the Korea Concrete Institute Conference
• /
• 1998.10a
• /
• pp.571-576
• /
• 1998

This paper is a part of a research plan aimed at the verification of basic design rules of high-strength concrete columns. A total of 19 slender column specimens were tested to measure secondary moment and stiffness of eccentrically loaded reinforced concrete tied columns. Main variables included in this test program were concrete compressive strength, steel amount, eccentricity, and slenderness ratio. The concrete compressive strength varied from 356kg/$\textrm{cm}^2$ to 951kg/$\textrm{cm}^2$, the longitudinal steel ratios were between 1.13% and 5.51%, and slenderness ratios were 40 and 61. Calculated moment magnification factors and column stiffness based on design codes are higher than the test results for high axial load under small eccentricity, for higher slenderness ratio, for lower longitudinal steel ratio, and for high-strength concrete. The moment magnification method of the current design codes may provide a very conservative design for high-strength concrete slender column.

• Architectural research
• /
• v.2 no.1
• /
• pp.61-69
• /
• 2000

This research focused on the hysteretic energy performance of 12 steel moment-resisting frames, which were intentionally designed by three types of design philosophies, strength control design, strength and drift control design, and strong-column and weak-beam control design. The energy performances of three designs were discussed In view of strength increase effect, stiffness increase effect, and strong-column and weak-beam effects. The mean hysteretic energy of the 12 basic systems were statically processed and compared to that of single-degree-of-freedom systems. Hysteretic energy was not always increased with an increase of strength and stiffness in the steel moment-resisting frames. Hysteretic energy between strong-column and weak-beam design and drift control design with the same stiffness was not sensitive each other for these types of mid-rises of steel moment-resisting frames.