• Journal of Marine Bioscience and Biotechnology
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• v.7 no.2
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• pp.58-70
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• 2015

Injectable RGD-bioconjugated Mussel Adhesive Proteins (RGD-MAPs) composite hydroxypropyl methylcellulose (HPMC) hydrogels provide local periodontal tissue for bone filling in periodontal surgery. Previously we developed a novel type of injectable self-supported hydrogel (2 mg/ml of RGD-MAPs/HPMC) based porcine nano hydroxyapatite (MPH) for dental graft, which could good handling property, biodegradation or biocompatibility with the hydrogel disassembly and provided efficient cell adhesion activity and no inflammatory responses. Herein, the aim of this work was to evaluate bone formation following implantation of MPH and collagen membrane in rabbit calvarial defects. Eight male New Zealand rabbits were used and four circular calvarial defects were created on each animal. Defects were filled with different graft materials: 1) collagen membrane, 2) collagen membrane with MPH, 3) collagen membrane with bovine bone hydroxyapatite (BBH), and 4) control. The animals were sacrificed after 2 and 8 weeks of healing periods for histologic analysis. Both sites receiving MPH and BBH showed statistically increased augmented volume and new bone formation (p < 0.05). However, there was no statistical difference in new bone formation between the MPH, BBH and collagen membrane group at all healing periods. Within the limits of this study, collagen membrane with MPH was an effective material for bone formation and space maintaining in rabbit calvarial defects.

• Membrane Journal
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• v.32 no.5
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• pp.292-303
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• 2022

An eco-friendly energy conversion device without the emission of pollutants has gained much attention due to the rapid use of fossil fuels inducing carbon dioxide emissions ever since the first industrial revolution in the 18th century. Polymer electrolyte membrane fuel cells (PEMFCs) that can produce water during the reaction without the emission of carbon dioxide are promising devices for automotive and residential applications. As a key component of PEMFCs, polymer electrolyte membranes (PEMs) need to have high proton conductivity and physicochemical stability during the operation. Currently, perfluorinated sulfonic acid-based PEMs (PFSA-PEMs) have been commercialized and utilized in PEMFC systems. Although the PFSA-PEMs are found to meet these criteria, there is an ongoing need to improve these further, to be useful in practical PEMFC operation. In addition, the well-known drawbacks of PFSA-PEMs including low glass transition temperature and high gas crossover need to be improved. Therefore, this review focused on recent trends in the development of high-performance PFSA-PEMs in three different ways. First, control of the side chain of PFSA copolymers can effectively improve the proton conductivity and thermal stability by increasing the ion exchange capacity and polymer crystallinity. Second, the development of composite-type PFSA-PEMs is an effective way to improve proton conductivity and physical stability by incorporating organic/inorganic additives. Finally, the incorporation of porous substrates is also a promising way to develop a thin pore-filling membrane showing low membrane resistance and outstanding durability.

• Analytical Science and Technology
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• v.20 no.4
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• pp.279-288
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• 2007

We have studied a method for the preparation of $ACF/TiO_2$ composites involving the penetrationof titanium n-butoxide (TNB) solution into activated carbon fiber. It was focused on the characterization of $TiO_2$ formed in prorous carbon was which increased with surface functional groups by hydrochloric acid treatment. The conversion of TNB to $TiO_2$ for the acid treatment effect must be important for the preparationof $ACF/TiO_2$ composites. From the characterization of surface properties, both the BET surface area and the total pore volume decreased as the distribution of $TiO_2$ on the activated carbon fiber surfaces after acid treatments.The changes in XRD pattern showed the typical anatase type on $ACF/TiO_2$ composite for the sample named FT, FT1 and FT2 treated with 0.05, 0.1 and 0.5 M, respectively. However, XRD patern of FT3 treated with 0.5M showed mixed amatase-rutile structure. According to the results of SEM micrographs, the titanium complexe particles were irregularly distributed around carbon. And some large clusters were found when an amount of acid treatment increased. The EDX results of $ACF/TiO_2$ composites showed the presence of C, O and P with strong Ti peaks. Finally, the excellent photocatalytic activity of the $ACF/TiO_2$ composites between relative concentration($c/c_o$) of MB (methylene blue) and UV irradiation time could be attributed to the both effects between photocatalysis of the formation of titania complexes and adsorptivity of the activated carbon fiber.

• Journal of Dental Rehabilitation and Applied Science
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• v.16 no.1
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• pp.51-60
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• 2000

The purpose of this study was to compare the microleakage at the interface of cast post and tooth according to the type of cement. Forty anterior teeth with single root were used. The teeth were cut 2 mm coronal from the cementoeamel junction and chamfer finish line was made on 1 mm coronal from the cementoeamel junction. After the routine endodontic treatment, post space was prepared using #5.5 Parapost drill to a depth of 7 mm. After the pick up impression, core building was made to 3 mm of clinical crown with burnout wax, then post and core was cast with nonprecious metal. The teeth were divided into four groups of ten each. In Group I, post and core were cemented with Fleck's(Zinc phosphate cement) In Group II, post and core were cemented with Fuji I(Glass ionomer cement) In Group III, post and core were cemented with Superbond C & B(Composite resin cement) In Group IV, post and core were cemented with Panavia 21(Composite resin cement) All cemented teeth were stored in normal saline at $37^{\circ}C$ for 7 days and thermocycled from $5^{\circ}C$ to $55^{\circ}C$ for 500 cycles with a dwell time of 30 seconds. After thermocycling, teeth were immersed in 1% Basic fuchsin dye for 48 hours. All 40 teeth were then embedded in the epoxy resin and cut buccolingually with a cutting instrument. The degree of penetration of dye at interface was graded on a scale of 0 to 4 using a stereomicroscope at 25 to 40 times magnification. Through the findings of this study, the following conclusion were obtained. 1. All the groups showed the microleakage at the interface of cast post core and tooth. 2. Group I showed the highest microleakage score among the groups with a significant difference(p<0.05). 3. Group II showed higher microleakage score than Group III and Group IV with a significant difference(p<0.05). 4. Group IV showed the lowest microleakage score but there were no significant difference with Group III(p>0.05).

• Korean Journal of Clinical Pharmacy
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• v.21 no.1
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• pp.30-35
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• 2011

The objective of this study was to find out drug use pattern of narcotic analgesics in university hospitals in Korea. A university hospital located in Kyungbuk province was chosen for this study. The drug use pattern was analyzed in terms of ingredient, administration route, patient type, and attending department. Amount of drug usage was counted by unit dose defined by the number of ampule or vial for injectable, tablet or capsule for oral, and each for patch preparations. Result showed that 11 narcotic analgesic ingredients were used during 2007-2009, and the drug usage was increased by about 20% annually during the period. Proportion of oral preparations used for pain management was about two third of all narcotic analgesics usage and kept increasing during the period. Proportion of the drug usage for outpatients was also steadily increased. Notably, the usage of oral preparations of oxycodone, morphine, and hydromorphone was rapidly increased for the management of cancer pain while the usage of codeine and codeine-containing composite preparations for cancer pain were minimal (<10%). About 90% of all narcotic analgesics were used by physicians in Internal Department, especially in Oncology Division of the Department. These findings suggest that pain management is becoming more aggressive and in agreement with WHO's guidelines regarding selection of administration route. However, in terms of 3-step ladder for cancer pain management, the drug use pattern was not congruent to WHO's guidelines. Therefore, in conclusion, it appears that physicians need to try to be congruent to the guidelines when using narcotic analgesics for cancer pain.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.28 no.10
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• pp.1526-1533
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• 2004

The needs of walking assistant device such as the Ankle Foot Orthosis (A.F.O) are getting greater than before. However, most of the A.F.O are generally imported rather than domestic manufacturing. The major reason of high import reliability is the rack of impact properties of domestic commercial products. Therefore, this research is going to focus on the evaluation of impact properties of the A.F.O which has the high import reliability. Unfortunately, these kinds of researches are not performed sufficiently. This research is going to evaluate impact energy behavior in composite materials such as the glass/epoxy (S-glass, [0/90]sub 2S/) and the aramid/epoxy (Kevlar-29, woven type, 8 ply) of ankle foot orthosis. The approach methods were as follows. 1) The history of impact load and impact energy due to the various velocities. 2) Relationship between the deflection and damage shape according to the impact velocities. 3) The behavior of absorbed energy and residual strength rate due to the various impact velocities.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.8 no.1
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• pp.33-40
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• 1988

The new technique has been used to determine the soil-reinforcement interaction. The testing apparatus is essentially a triaxial cell fitted with the capability to house a hollow cylinderical sample. A hollow cylinderical sand specimen with a concentrical layer of reinfarcing material sandwitched in the middle is used in this investigation. The reinforcement is fastened at the base. The hollow specimen can be viewed as a "unit sheet" of a soil-reinforcement composite system of infinite horizontal extent. Axial load as well as inner and outer chamber pressures can be applied to perform a test. The specimen is first subjected to an isotropic stress state corresponding to the overburden pressure. Next, an extension test by reducing the axial load is carried out. The specimen is "loaded" to failure by either the breakage of reinforcing material (tensile failure) or slippage which takes place at the soil-reinforcement interface (i.e. the overcoming of the bonding capacity). Since the reinforcement is fastened at its lower end to the base, any tendency of relative movement between the reinforcement and the sand during an extension test can induce tensile force in the reinforcement thus forming a "reversed pull-out" test condition. Preliminary test results have demonstrated positively of the new approach to test the soil-reinforcement interaction. Reinforcing elements of different extensibility were used to study the deformbility of reinforced soil. Furthermore, both the breakage and the pull-out modes of failure were observed.

• Atmosphere
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• v.20 no.4
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• pp.415-426
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• 2010

A Land cover map over East Asian region (Kongju national university Land Cover map: KLC) is classified by using support vector machine (SVM) and evaluated with ground truth data. The basic input data are the recent three years (2006-2008) of MODIS (MODerate Imaging Spectriradiometer) NDVI (normalized difference vegetation index) data. The spatial resolution and temporal frequency of MODIS NDVI are 1km and 16 days, respectively. To minimize the number of cloud contaminated pixels in the MODIS NDVI data, the maximum value composite is applied to the 16 days data. And correction of cloud contaminated pixels based on the spatiotemporal continuity assumption are applied to the monthly NDVI data. To reduce the dataset and improve the classification quality, 9 phenological data, such as, NDVI maximum, amplitude, average, and others, derived from the corrected monthly NDVI data. The 3 types of land cover maps (International Geosphere Biosphere Programme: IGBP, University of Maryland: UMd, and MODIS) were used to build up a "quasi" ground truth data set, which were composed of pixels where the three land cover maps classified as the same land cover type. The classification results show that the fractions of broadleaf trees and grasslands are greater, but those of the croplands and needleleaf trees are smaller compared to those of the IGBP or UMd. The validation results using in-situ observation database show that the percentages of pixels in agreement with the observations are 80%, 77%, 63%, 57% in MODIS, KLC, IGBP, UMd land cover data, respectively. The significant differences in land cover types among the MODIS, IGBP, UMd and KLC are mainly occurred at the southern China and Manchuria, where most of pixels are contaminated by cloud and snow during summer and winter, respectively. It shows that the quality of raw data is one of the most important factors in land cover classification.

• Steel and Composite Structures
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• v.23 no.2
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• pp.195-204
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• 2017

The effects of plaster on the behavior of single-story single-bay masonry-infilled steel frames under in-plane base accelerations have been experimentally investigated by a shake-table. Tested structures were made in a 1/3 scale, with realistic material properties and construction methods. Steel frames with high and low flexural rigidity of beams and columns were considered. Each type of frame was tested with three variants of masonry: (i) non-plastered masonry; (ii) masonry infill with conventional plaster on both sides; and (iii) masonry infill with a polyvinyl chloride (PVC) net reinforced plaster on both sides. Masonry bricks were made of lightweight cellular concrete. Each frame was firstly successively exposed to horizontal base accelerations of an artificial accelerogram, and afterwards, to horizontal base accelerations of a real earthquake. Characteristic displacements, strains and cracks in the masonry were established for each applied excitation. It has been concluded that plaster strengthens the infill and prevents damages in it, which results in more favorable behavior and increased bearing capacity of plastered masonry-infilled frames compared to non-plastered masonry-infilled frames. The load-bearing contribution of the adopted PVC net in the plaster was not noticeable for the tested specimens, probably due to relative small cross section area of fibers in the net. Behavior of masonry-infilled steel frames significantly depends on frame stiffness. Strong frames have smaller displacements than weak frames, which reduces deformations and damages of an infill.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.5 no.1
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• pp.43-53
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• 1985

This study proposes a reliability based design criteria for the steel bridge (H-beam, plate-girder and composite-beam), which is most common type of steel bridge, and also proposes the theoretical bases of nominal safety factors as well as load and rasistance factors based on the reliability theory. Major 2nd moment reliability analysis and design theories including both Cornell's MFOSM (Mean First Order 2nd Moment) Methods and Lind-Hasofer's AFOSM(Advanced First Order 2nd Moment) Methods are summarized and compared, and it has been found that Lind-Hasofer's approximate and an approximate Log-normal type reliability formula are well suited for the proposed reliability study. A target reliability index (${\beta}_0=3.5$) is selected as an optimal value considering our practice based on the calibration with the safety pravisions of the current steel bridge design code. Galambo's theory is used for the derivation of the algorithm for the evaluation of uncertainties associated with resistences by LRFD Format and SGST Format, whereas the magnitude of the uncertainties associated with load effects are chosen primarily by considering our level of practice. It may be concluded that the proposed LRFD reliability based design provisions for the steel highway bridge give more rational design than the current standard code for steel highway bridge.