• Bulletin of the Korean Chemical Society
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• 제25권2호
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• pp.289-292
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• 2004

A trisaccharide, GlcNAcp- ${\beta}-(1{\to}3)-Galp-{\alpha}-(1{\to}2)$-6-deoxy-altroHepp- ${\alpha}-(1{\to}O$-propyl, as an O-antigenic repeating unit of C. jejuni serotype O:23 and O:36 was synthesized. Coupling of the GlcNPhth-(1${\to}$3)-Gal disaccharide donor with allyl 6-deoxy-altroHep acceptor in the presence of iodonium dicollidine perchlorate (IDCP) promoter afforded the ${\alpha}$-galactosidic trisaccharide with high stereoselectivities. Subsequent deacetalation, dephthaloylation, N-acetylation, and hydrogenolytic debenzylation furnished the title compound.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제7권1호
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• pp.77-84
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• 2001

This study provide the planning guidelines for the existing and the new alternative. On the bases of survey and analysis, the basic data for OP-Unit have been proposed in consideration of the development of medical science and hygiene, economic conditions during the last twenty years in Germany. The results of the study were firstly, genera1 basic data, secondly, guidelines of the architectural design for OP-Unit und rooms, thirdly, new alternative OP-Unit with 2 and 3 operation rooms.

• Experimental and Molecular Medicine
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• 제50권12호
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• pp.13.1-13.12
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• 2018

We aimed to explore whether changes in circulating levels of miRNAs according to type 2 diabetes mellitus (T2DM) or prediabetes status could be used as biomarkers to evaluate the risk of developing the disease. The study included 462 patients without T2DM at baseline from the CORDIOPREV trial. After a median follow-up of 60 months, 107 of the subjects developed T2DM, 30 developed prediabetes, 223 maintained prediabetes and 78 remained disease-free. Plasma levels of four miRNAs related to insulin signaling and beta-cell function were measured by RT-PCR. We analyzed the relationship between miRNAs levels and insulin signaling and release indexes at baseline and after the follow-up period. The risk of developing disease based on tertiles (T1-T2-T3) of baseline miRNAs levels was evaluated by COX analysis. Thus, we observed higher miR-150 and miR-30a-5p and lower miR-15a and miR-375 baseline levels in subjects with T2DM than in disease-free subjects. Patients with high miR-150 and miR-30a-5p baseline levels had lower disposition index (p = 0.047 and p = 0.007, respectively). The higher risk of disease was associated with high levels (T3) of miR-150 and miR-30a-5p ($HR_{T3-T1}=4.218$ and $HR_{T3-T1}=2.527$, respectively) and low levels (T1) of miR-15a and miR-375 ($HR_{T1-T3}=3.269$ and $HR_{T1-T3}=1.604$, respectively). In conclusion, our study showed that deregulated plasma levels of miR-150, miR-30a-5p, miR-15a, and miR-375 were observed years before the onset of T2DM and pre-DM and could be used to evaluate the risk of developing the disease, which may improve prediction and prevention among individuals at high risk for T2DM.

• 호남수학학술지
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• 제38권2호
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• pp.375-384
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• 2016

In this paper, we study the pseudo-symmetry of unit tangent sphere bundle. We prove that if the unit tangent sphere bundle $T_1M$ with standard contact metric structure over a locally symmetric $M^n$, $n{\geq}3$ is pseudo-symmetric, then M is of constant curvature.

• Journal of Hospice and Palliative Care
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• 제3권1호
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• pp.18-27
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• 2000

목적 : 본 연구는 강남성모병원 호스피스 병동에 입원한 환자들의 입원 시 삶의 질과 간호서비스를 받는 동안 삶의 질 변화와 호스피스 간호서비스가 말기환자의 삶의 질에 미치는 영향을 알아보고자 시도하였다. 방법 : 1999년 10월부터 2000년 3월 사이에 가톨릭 대학교 강남성모병원 호스피스 병동에 입원한 환자와 가족 100명을 대상으로 연구자가 수정, 보완하여 개발한 설문지를 통해 자료를 수집하였고, 수집된 자료는 repeated measures ANOVA로 분석하였다. 결과 : 1) 간호제공자에 의해 인지된 환자의 삶의 질 평점은 입원시, 입원 1, 2, 3, 4주에 각각 3.31, 3.68, 3.56, 3.73, 3.75로 입원 당시보다 시간이 지남에 따라 유의하게 향상되었고, 입원시점에 따라 항목별로 살펴 볼 때 "신체적 청결"(F=6.50, P=0.0001) "통증조절"(F=18.01., P=0.0001) "대변상태"(F=2.96, P=0.0237) "수면상태"(F=3.99, P=0.0048) "메스꺼움/구토"(F=4.50, P=0.0022) "의료진의 편안한 돌봄"(F=3.95, P=0.0051) "가족들의 돌봄"(F=2.76, P=0.0317) "불안감"(F=3.14, P=0.0177) "마음이 편안함"(F=3.63, P=0.0085) "인간적인 대우"(F=3.32, P=0.0136) "죽음이 끝이 아니라 새로운 시작이라고 생각함"(F=2.54, P=0.0450) 등의 항목에서 유의한 차이가 있었다. 2) 환자 자신에 의해 인지된 삶의 질 평점은 입원 시와 입원 1주에 각각 3.63, 3.83으로 향상되었지만 유의한 차이는 보이지 않았다. 입원시점에 따라 항목별로 살펴볼 때 "통증조절" 항목만이 유의한 변화를 보였다. 3) 사망시점으로부터 삶의 질 평점은 사망 5주전, 4주전, 3주전, 2주전, 1주전에 각각 3.48, 3.51, 3.44, 3.46, 3.50이었으며 유의한 차이는 없었다. 결론 : 본 연구의 결과 호스피스 서비스는 말기 환자의 삶의 질에 긍정적인 영향을 주는 것으로 보여졌다. 따라서 호스피스 서비스의 질 향상을 위해 호스피스 환자들을 지지해 줄 중재방안을 모색해야 하며, 특히 간호의 영적 영역에 초점을 두어야 하겠다. 또한 말기 환자의 주관적인 삶의 질 측정을 위해 도구개발이 이루어져야 하며 대상자를 확대하여 계속적인 연구가 있어야 할 것으로 생각된다.

• Bulletin of the Korean Chemical Society
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• 제10권3호
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• pp.234-238
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• 1989

The crystal structure of partially $Ag^+$-exchanged zeolite A, $Ag_{3.2}Na_{8.8}$-A, vacuum dehydrated at $360^{\circ}C$ and then exposed to 0.1 torr of cesium vapor for 12 hours at $250^{\circ}C$ has been determined by single-crystal X-ray diffraction techniques in the cubic space group Pm3m (a = 12.262(2)${\AA})\;at\;21(1)^{\circ}C$. The structure was refined to the final error indexes $R_1=0.068\;and\;R_2=0.072$ by using 338 reflections for which $I_o\;>\;3{\sigma}(I_o)$ and the composition of unit cell is $Ag_{3.2}Cs_{8.8}-A.\;3\;Cs^+$ ions lie on the centers of the 8-rings at sites of D4h symmetry. Two crystallographycally different 6-ring $Cs^+$ ions were found: 1.5 $Cs^+$ ions at Cs(2) are located inside of sodalite cavity and 4.3 $Cs^+$ ions at Cs(3) are located in the large cavity. The fractional occupancies observed at Cs(2) and Cs(3) indicate that the existence of at least three types of unit cells with regard to the 6-ring $Cs^+$ ions. For example, 50% of unit cells may have two $Cs^+$ ions at Cs(2) and 4 $Cs^+$ ions at Cs(3). 30% of unit cells may have one Cs+ ion at Cs(2) and 5 $Cs^+$ ions at Cs(3). The remaining 20% would have one $Cs^+$ ion at Cs(2) and 4 $Cs^+$ ions at Cs(3). On threefold axes of the unit cell two non-equivalent Ag atom positions are found in the large cavity, each containing 0.64 and 1.92 Ag atoms, respectively. A crystallographic analysis may be interpreted to indicate that 0.64 $(Ag_5)^+$ clusters are present in each large cavity. This cluster may be viewed as a tetrasilver molecule $(Ag_4)^0$(bond length, 2.84${\AA}$) stabilized by the coordination of one $Ag^+$ ion.

• 간호행정학회지
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• 제3권2호
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• pp.17-40
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• 1997

The purpose of this descriptive, correlational study was to identify, describe the patterns of nursing unit culture, nursing performance, job satisfaction and turnover intention in the hospital setting, and to analyze the relationships between nursing unit culture, nursing performance, job satisfaction and turnover intention among the characteristic of the subjects The subject consisted of 223 nurses who were employed in medical & surgical units of 3 different University hospitals in Seoul. Data collection was done in November, 1996 by means of questionnaire. The instruments used for this study were the questionnaire based on the Nursing unit cultural assessment tool developed by Coeling(1993), Nursing performance scale used by Yoon(1991), Job satisfaction scale developed by Slavitt, et al.(1978) and Turnover intention scale used by Lee(1995). The data were analyzed by percentage distribution. Pearson correlation coefficient and ANOVA. The summarized results were as follows: 1. There was significant differences in the nursing unit culture between individual cultural behavior and group cultural behavior. 2. There was positive correlation between nursing unit culture, nursing performance and job satisfaction. 3. There was negative correlation between nursing unit culture and turnover intention. 4. There was significant difference in nursing performance efficiency according to the age, educational level, professional carrier in the nursing unit, in the hospital. 5. There was significant difference in turnover intention according to the age, educational level. According to these results, the following implications can be made ; 1. It needs to study on the nursing unit culture in other size hospitals and compare them to these results. 2. It is necessary to assess nursing unit culture and endeaveor good climate for the nursing organizational outcomes and prepare the training course of leadership of nurse manager. 3. In nursing administration, there should be an emphasis on assessment of staff nurses' cultural behavior in case of nurses' orientation, allocation, recruitment, continuning education, so that staff nurses' performance and job satisfaction will be increased and trunover intention will be decreased.

• 한국주거학회논문집
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• 제11권2호
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• pp.129-137
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• 2000

This study is about the difference of South and East facing Cooling load of Apartment s Houses using Dynamic Heat-flow Calculation. Therefore, the purpose of this study is come in to use Material for the Thermal Environments of Apartment Houses. The results of the analysis are below. (1) For the peak load of degree hour; The highest is "I" unit and the next high load is H, F, E, C, B, G, D and A unit for the south facing Apartment houses. The higher load is "H" unit and the next high load is I, E, F, B, C, G, D, A Unit for the east facing Apartment houses. (2) For the total load of degree day; The highest load is "I" unit and the next high load is H, G, F, E, C, B, D and A Unit for the south facing Apartment houses. The highest load is "H" unit and the next high load is I, G, E, F, B, C, D, A Unit for the east facing Apartment houses. (3) For the total load of degree day; The highest load is "H" Unit for the east facing Apartment houses and the Lowest load is "A" Unit for the south facing Apartment houses.is "A" Unit for the south facing Apartment houses.nt houses.

• 한국실내디자인학회논문집
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• 제38호
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• pp.116-124
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• 2003

The purpose of this study was provide basic data for homemakers' housing notion according to unit size in apartment. This study was conducted by questionnaires that concerning about middle class homemakers whom they lived in Bundang. The results of this study were as follows; 1) In research on the homemakers' general quality, 20pyung unit size was alike 30pyung unit size and 40pyung unit size was similar to 50pyung unit size. 2) Homemakers' perception according to unit size in apartment was various; (a) 20pyungㆍ30pyung unit size-effective household space for husbands' participation, more sports facilities, parking lot space etc. (b) 40pyungㆍ50pyung unit size-homemakers' individual room, ordering and variable unit plan etc. 3) In research on the homemakers' needs, each of unit size was analogous to storage, common facility, new design and new housing form etc.

• 전기의세계
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• 제14권4호
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• pp.8-17
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• 1965

Firstly, this study has analyzed the following factors affecting the optimum specifications and design of distributive transformers: 1. Facilities installation cost per unit power output. 2. Facilities operating & maintenance cost per unit power output. 3. Production cost per unit power output. 4. Load factor. 5. Loss factor. Secondly, it has clarified the relations between the following factors and the specifications and design of distributive transformers; 1. No-load loss., 2. Load loss., 3. Voltage regulation., 4. Exciting current. Finally, it has determined the method of the most economic design for the transformers using the above factors and relations, and, for optimum the illustrative purpose, suggested their optimum specifications, way of evaluation, and merits by means of typical example.