• Title/Summary/Keyword: 0D model

Search Result 3,216, Processing Time 0.04 seconds

Theoretical Study of Various Unit Models for Biomedical Application

  • Choi, Jeongho
    • Journal of the Korean Society of Industry Convergence
    • /
    • v.22 no.4
    • /
    • pp.387-394
    • /
    • 2019
  • This paper presents an analytical study on the strength and stiffness of various types of truss structures. The applied models are triangular-like opened truss-wall triangular model (OTT), closed truss-wall triangular model (CTT), opened solid-wall triangular model (OST), and hypercube models defined as core-filled or core-spaced cube. The models are analyzed by numerical model analysis using DEFORM 2D/3D tool with AISI 304 stainless steel. Then, the ideal solutions for stiffness and strength are defined. Finally, the relative elastic modulus of the core-spaced model is obtained as 0.0009, which is correlated with the cancellous bone for the relative density range of 0.029-0.03, and the relative elastic modulus for the core-filled model is obtained as 0.0015, which is correlated with cancellous bone for the relative density range of 0.035-0.036. For the relative compressive yield strength, the OTT reasonably agrees with the cancellous bone for the relative density of 0.042 and the relative compressive strength of 0.05. The CTT and OST are in good agreement at the relative density of 0.013 and the relative compressive yield strength of 0.002. The hypercube models can be used for the cancellous bone for stiffness, and the triangular models can be used for the cancellous bone for strength. However, none of the models can be used to replace the compact bone because it requires much higher stiffness and strength. In the near future, compact bone replacement must be further studied. In addition, previously mentioned models should be developed further.

Comparison Study of O/D Estimation Methods for Building a Large-Sized Microscopic Traffic Simulation Network: Cases of Gravity Model and QUEEENSOD Method (대규모 미시교통시뮬레이션모형 구축을 위한 O/D 추정 방법 성능 비교 - 중력모형과 QUEENSOD 방법을 중심으로 -)

  • Yoon, Jung Eun;Lee, Cheol Ki;Lee, Hwan Pil;Kim, Kyung Hyun;Park, Wonil;Yun, Ilsoo
    • International Journal of Highway Engineering
    • /
    • v.18 no.2
    • /
    • pp.91-101
    • /
    • 2016
  • PURPOSES : The aim of this study was to compare the performance of the QUEENSOD method and the gravity model in estimating Origin-Destination (O/D) tables for a large-sized microscopic traffic simulation network. METHODS : In this study, an expressway network was simulated using the microscopic traffic simulation model, VISSIM. The gravity model and QUEENSOD method were used to estimate the O/D pairs between internal and between external zones. RESULTS: After obtaining estimations of the O/D table by using both the gravity model and the QUEENSOD method, the value of the root mean square error (RMSE) for O/D pairs between internal zones were compared. For the gravity model and the QUEENSOD method, the RMSE obtained were 386.0 and 241.2, respectively. The O/D tables estimated using both methods were then entered into the VISSIM networks and calibrated with measured travel time. The resulting estimated travel times were then compared. For the gravity model and the QUEENSOD method, the estimated travel times showed 1.16% and 0.45% deviation from the surveyed travel time, respectively. CONCLUSIONS : In building a large-sized microscopic traffic simulation network, an O/D matrix is essential in order to produce reliable analysis results. When link counts from diverse ITS facilities are available, the QUEENSOD method outperforms the gravity model.

Various Partial Charge Schemes on 3D-QSAR Models for P-gp Inhibiting Adamantyl Derivatives

  • Gadhe, Changdev G.;Madhavan, Thirumurthy;Kothandan, Gugan;Lee, Tae-Bum;Lee, Kyeong;Cho, Seung-Joo
    • Bulletin of the Korean Chemical Society
    • /
    • v.32 no.5
    • /
    • pp.1604-1612
    • /
    • 2011
  • We developed three-dimensional quantitative structure activity relationship (3D-QASR) models for 17 adamantyl derivatives as P-glycoprotein (P-gp) inhibitors. Eighteen different partial charge calculation methods were tested to check the feasibility of the 3D-QSAR models. Best predictive comparative molecular field analysis (CoMFA) model was obtained with the Austin Model 1-Bond Charge Correction (AM1-BCC) atomic charge. The 3D-QSAR models were derived with CoMFA and comparative molecular similarity indices analysis (CoMSIA). The final CoMFA model ($q^2$ = 0.764, $r^2$ = 0.988) was calculated with an AM1-BCC charge and electrostatic parameter, whereas the CoMSIA model ($q^2$ = 0.655, $r^2$ = 0.964) was derived with an AM1-BCC charge and combined steric, electrostatic, hydrophobic and HB-acceptor parameters. Leave-five-out (LFO) cross-validation was also performed, which yielded good correlation coefficient for both CoMFA (0.801) and CoMSIA (0.656) models. Robustness of the developed models was checked further with 1000 run bootstrapping analyses, which gave an acceptable correlation coefficient for CoMFA (BS-$r^2$ = 0.997, BS-SD = 0.003) and CoMSIA (BS-$r^2$ = 0.996, BS-SD = 0.018).

A Study on the Predictive Model of Propagation Path Loss in Millimeter-Wave Band (밀리미터파 대역에서 전파경로손실 예측 모델)

  • Kim, Song-Min
    • Journal of the Institute of Electronics Engineers of Korea TE
    • /
    • v.42 no.2
    • /
    • pp.23-28
    • /
    • 2005
  • This study was to suggest the propagation path loss and predictive model of propagation path analysis in order to apply the frequency in the millimeter-wave band to the real time inter-vehicle communication system. This study was to suppose the case of inter-vehicle communication on the one-way two-lanes road in the big cites with a lot of traffic jams in order to analyze the effect by the reflected wave of multipath. As a simulation of suggested model, it found out that the propagation path by the reflected wave was about 0.1[m]$\sim$5.1[m] longer than the one by the direct wave during the transmission of 100[m] wave direct path. Also, as a result of comparing the propagation path loss, the loss would be about -0.8[dB]$\sim$-4.2[dB] larger in case of wall reflection and -0.8[dB]$\sim$-1[dB] vehicle reflection. From the result above, this researcher found out that the path loss of reflected wave produced by the walls was about -3.2[dB] larger than the path loss produced by the adjacent vehicles.

Use of Frequencies of Micronuclei as Biological Dosimetry in Korean Native Cattle and Goat Lymphocytes after Irradiation in vitro (한우 및 한국재래산양 유래 말초혈액 림프구의 미소핵을 이용한 방사선 피폭의 생물학적 선량측정)

  • 류시윤;김민주;김호준;조성환;김태환;정규식;이해준;김성호
    • Journal of Veterinary Clinics
    • /
    • v.19 no.3
    • /
    • pp.290-294
    • /
    • 2002
  • The frequencies of gamma-ray-induced micronuclei (MN) in cytokinesis-blocked (CB) lymphocytes at several doses were measured in three donors of Korean native cattle and Korean native goat. Measurements performed after irradiation showed a dose-related increases in MN frequency in each of the donors studied. When analysed by linear-quadratic model the line of best fit was cattle : y : 0.1016D +$0.0118D^2$+0.0147, goat : y = 0.1353D +$0.0043D^2$+0.0087 (y : number of MN/CB cells and D = irradiation dose in Gy). The relative sensitivity of goat lymphocytes compared with cattle lymphocytes was estimated by best fitting linear-quadratic model based on the radiation-induced MN data over the range from 0 Gy to 4 Gy. In the case of MN frequency with 0.05, 0.1, 0.2, 0.4 and 0.8, the relative sensitivities of goat lymphocytes were 1.106. 1.166. 1.140, 1.069 and 0.976 respectively. Our in vitro radiobiological study confirmed that the cytogenetic response obtained in blood from cattle and goat can be utilized for application in environmental studies.

Design of Deep De-nosing Network for Power Line Artifact in Electrocardiogram (심전도 신호의 전력선 잡음 제거를 위한 Deep De-noising Network 설계)

  • Kwon, Oyun;Lee, JeeEun;Kwon, Jun Hwan;Lim, Seong Jun;Yoo, Sun Kook
    • Journal of Korea Multimedia Society
    • /
    • v.23 no.3
    • /
    • pp.402-411
    • /
    • 2020
  • Power line noise in electrocardiogram signals makes it difficult to diagnose cardiovascular disease. ECG signals without power line noise are needed to increase the accuracy of diagnosis. In this paper, it is proposed DNN(Deep Neural Network) model to remove the power line noise in ECG. The proposed model is learned with noisy ECG, and clean ECG. Performance of the proposed model were performed in various environments(varying amplitude, frequency change, real-time amplitude change). The evaluation used signal-to-noise ratio and root mean square error (RMSE). The difference in evaluation metrics between the noisy ECG signals and the de-noising ECG signals can demonstrate effectiveness as the de-noising model. The proposed DNN model learning result was a decrease in RMSE 0.0224dB and a increase in signal-to-noise ratio 1.048dB. The results performed in various environments showed a decrease in RMSE 1.7672dB and a increase in signal-to-noise ratio 15.1879dB in amplitude changes, a decrease in RMSE 0.0823dB and a increase in signal-to-noise ratio 4.9287dB in frequency changes. Finally, in real-time amplitude changes, RMSE was decreased 0.3886dB and signal-to-noise ratio was increased 11.4536dB. Thus, it was shown that the proposed DNN model can de-noise power line noise in ECG.

Weak Convergence for Nonparametric Bayes Estimators Based on Beta Processes in the Random Censorship Model

  • Hong, Jee-Chang
    • Communications for Statistical Applications and Methods
    • /
    • v.12 no.3
    • /
    • pp.545-556
    • /
    • 2005
  • Hjort(1990) obtained the nonparametric Bayes estimator $\^{F}_{c,a}$ of $F_0$ with respect to beta processes in the random censorship model. Let $X_1,{\cdots},X_n$ be i.i.d. $F_0$ and let $C_1,{\cdot},\;C_n$ be i.i.d. G. Assume that $F_0$ and G are continuous. This paper shows that {$\^{F}_{c,a}$(u){\|}0 < u < T} converges weakly to a Gaussian process whenever T < $\infty$ and $\~{F}_0({\tau})\;<\;1$.

Impacts of Initial Soil Moisture on Hydrologic Outflow in a Distributed FLO-2D Model (분포형 FLO-2D 수문모형에서 초기토양함수가 유출결과에 미치는 영향)

  • Lee, Khil-Ha
    • Journal of Environmental Science International
    • /
    • v.30 no.8
    • /
    • pp.613-619
    • /
    • 2021
  • Soil water enters the atmosphere via evapotranspiration, where it transforms into atmospheric water vapor and plays important role in the surface-atmosphere energy exchange. Soil conditions have a direct influence on the effective rainfall, and initial soil moisture conditions are important for quantitatively evaluating the effective rainfall in a watershed. To examine the sensitivity of the initial saturation to hydrologic outflow, a two-dimensional distributed FLO-2D hydrologic model was applied to a small watershed. The initial saturation was set to 0.3, 0.5, and 0.7 and the obtained results were compared. The Green-ampt model was chosen to calculate the penetration loss. Depending on the initial soil moisture, the peak flow rate varied by up to 60%, and the total water volume in the watershed by approximately 40%.

The Contribution of Innovation on Productivity and Growth in Korea (기술혁신이 생산성과 경제성장에 미치는 영향)

  • Kim, Byung-Woo
    • Journal of Korea Technology Innovation Society
    • /
    • v.11 no.1
    • /
    • pp.72-90
    • /
    • 2008
  • What has been the contribution of industrial innovation to economic growth? Typically, the issue has been approached with growth-accounting methods augmented to include a "stock of knowledge". An independent estimate of the rate of return to R&D is found in order to impute patents granted to the accumulation of knowledge. Griliches(1973) then uses a regression approach to assess the effect of an R&D variable on the computed TFP growth rate. The regression coefficient on the R&D variable would provide an estimate of the social rate of return to R&D. The related studies tend to show high social rates of return to R&D, typically in a range of 20 to 40 % per year. We need to provide multiple equation dynamic system for productivity and innovation in Korean economy in state space form. A wide range of time series models, including the classical linear regression model, can be written and estimated as special cases of a state space specification. State space models have been applied in the econometrics literature to model unobserved variables like productivity. Estimation produces the following results. Considering the goodness of fit, we can see that the evidence is strongly in favor of the range $0.120{\sim}0.135$ for the elasticity of TFP to R&D stock in the period between 1970's and the early 2000's.

  • PDF

2D-QSAR Analyses on The Tyrosinase Inhibitory Activity of 2-[(2,6-Dioxocyclohexyl)methyl]-cyclohexane-1,3-dione Analogues (2-[(2,6-Dioxocyclohexyl)methyl]cyclohexane-1,3-dione 유도체의 Tyrosinase 저해활성에 관한 2D-QSAR 분석)

  • Kim, Sang-Jin;Sung, Nack-Do
    • Journal of the Society of Cosmetic Scientists of Korea
    • /
    • v.40 no.4
    • /
    • pp.383-390
    • /
    • 2014
  • The following conclusion was made from the 2D-QSAR model for the tyrosinase inhibitory activity according to the variation of the substituents R1 and R2 in analogues of compound 2-[(2,6-dioxocyclohexyl)methyl]cyclohexane- 1,3-dione (1-23). The best optimized 2D-QSAR model was $Obs.pI_{50}=-0.295({\pm}0.031)TDM$ $-0.120({\pm}0.014)DMZ+0.135({\pm}0.050)DMX.R_2+6.382({\pm}0.17)$, and the correlation $r^2=0.905$) of which was greater than its predictability ($q^2=0.843$). The magnitude of the effect of tyrosinase inhibitory activities was in order of TDM > $DMX.R_2{\geq}DMZ$, and it tended to increase as the hydrophobicity of substrate molecule (ClogP > 0) as well as the steric favor of substituent $R_1$ increased. The analysis of the model implies that inhibitory activity of substrate molecule will increase as $DMX.R_2$ (Dipole moment X component of $R_2$-substituent) increases, while TDM (Total Dipole Moment) and DMZ(Dipole Moment of Z-Component) decrease. As such, it is deemed feasible to conclude, that in order to increase the inhibitory effect, it would be rather desirable to replace the polar groups within the molecules with non-polar functional groups.