• Title/Summary/Keyword: 04A25

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Sediment Provenance using Clay Mineral in the Continental Shelf and Rise of the Eastern Bellingshausen Sea, Antarctica (벨링스하우젠 해의 동쪽 대륙붕과 대륙대의 코어의 점토광물을 이용한 기원지 연구)

  • Park, Young Kyu;Jung, Jaewoo;Lee, Kee-Hwan;Lee, Minkyung;Kim, Sunghan;Yoo, Kyu-Cheul;Lee, Jaeil;Kim, Jinwook
    • Journal of the Mineralogical Society of Korea
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    • v.32 no.3
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    • pp.173-184
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    • 2019
  • Variations in grain size distribution and clay mineral assemblage are closely related to the sedimentary facies that reflect depositional conditions during the glacial and interglacial periods. Gravity cores BS17-GC15 and BS17-GC04 were collected from the continental shelf and rise in the eastern Bellingshausen Sea during a cruise of the ANA07D Cruise Expedition by the Korea Polar Research Institute in 2017. Core sediments in BS17-GC15 consisted of subglacial diamicton, gravelly muddy sand, and bioturbated diatom-bearing mud from the bottom to the top sediments. Core sediments in BS17-GC04 comprised silty mud with turbidites, brownish structureless mud, laminated mud, and brownish silty bioturbated diatom-bearing mud from the bottom to the top sediments. The clay mineral assemblages in the two core sediments mainly consisted of smectite, chlorite, illite, and kaolinite. The clay mineral contents in core GC15 showed a variation in illite from 28.4 % to 44.5 % in down-core changes. Smectite contents varied from 31.1 % in the glacial period to 20 % in the deglacial period and 25.1 % in the interglacial period. Chlorite and kaolinite contents decreased from 40.5 % in the glacial period to 30.3 % in the interglacial period. The high contents of illite and chlorite indicated a terrigenous detritus supply from the bedrocks of the Antarctic Peninsula. Core GC04 from the continental rise showed a decrease in the average smectite content from 47.2 % in the glacial period to 20.6 % in the interglacial period, while the illite contents increased from the 21.3 % to 43.2 % from the glacial to the interglacial period. The high smectite contents in core GC04 during the glacial period may be supplied from Peter I Island, which has a known smectite-rich sediment contributed by Antarctic Circumpolar Currents. Conversely, the decrease in smectite and increase in chlorite and illite contents during the interglacial period was likely caused by a higher supply of chlorite- and illite-enriched sediment from the eastern Bellingshausen Sea shelf by the southwestward flowing contour current.

Susceptible and Protective Associations of HLA Alleles and Haplotypes with Cervical Cancer in South India

  • Rathika, Chinniah;Murali, Vijayan;Dhivakar, Mani;Kamaraj, Raju;Malini, Ravi Padma;Ramgopal, Sivanadham;Balakrishnan, Karuppiah
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.5
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    • pp.2491-2497
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    • 2016
  • Background: Human leukocyte antigen (HLA) genes have been implicated in cervical cancer in several populations. Objectives: To study the predispositions of HLA alleles/haplotypes with cervical cancer. Materials and Methods: Clinically diagnosed and PAP smear confirmed cervical cancer patients (n 48) and age matched controls (n 47) were genotyped for HLA-A,-B,-DRB1* and DQB1* alleles by PCR-SSP methods. Results: The frequencies of alleles DRB1*04 (OR=2.57), DRB1*15 (OR=2.04), DQB1*0301 (OR=4.91), DQB1*0601 (OR=2.21), B*15 (OR=13.03) and B*07 (OR=6.23) were higher in cervical cancer patients than in the controls. The frequencies of alleles DRB1*10 (OR=0.22) and B*35 (OR=0.19) were decreased. Strong disease associations were observed for haplotypes DRB1*15-DQB1*0601 (OR=6.56; p< $3.5{\times}10^{-4}$), DRB1*14-DQB1*0501 (OR=6.51; p<0.039) and A*11-B*07 (OR=3.95; p<0.005). The reduced frequencies of haplotypes DRB1*10-DQB1*0501 (OR=0.45), A*03-B*35 (OR=0.25) and A*11-B*35 (OR= 0.06) among patients suggested a protective association. HLA-C* typing of 8 patients who possessed a unique three locus haplotype 'A*11-B*07-DRB1*04' (8/48; 16.66%; OR=6.51; p<0.039) revealed the presence of a four locus haplotype 'A*11-B*07-C*01-DRB1*04' in patients (4/8; 50%). Amino acid variation analysis of susceptible allele DQB1*0601 suggested 'tyrosine' at positions ${\beta}9$ and ${\beta}37$ and tyrosine-non-tyrosine genotype combination increased the risk of cervical cancer. Conclusions: Strong susceptible associations were documented for HLA alleles B*15, B*07, DRB1*04, DRB1*15, DQB1*0301, DQB1*0601 and haplotypes DRB1*15-DQB1*0601 and DRB1*14-DQB1*0501. Further, protective associations were evidenced for alleles B*35 and DRB1*10 and haplotypes A*11-B*35 and DRB1*10-DQB1*0501 with cervical cancer in South India.

Magnetic and Magnetocaloric Properties of (Gd1-xCex)Al2(x = 0, 0.25, 0.5, 0.75) Compounds

  • Gencer, H.;Izgi, T.;Kolat, V.S.;Kaya, A.O.;Atalay, S.
    • Journal of Magnetics
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    • v.16 no.4
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    • pp.337-341
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    • 2011
  • The magnetic and magnetocaloric properties of $Gd_{1-x}Ce_xAl_2$ (x = 0, 0.25, 0.5, 0.75) intermetallic compounds alloys have been investigated in detail for the first time. XRD patterns indicated that all the samples were crystallized in a single phase with $MgCu_2$-type structure (Laves phase). Ce substitution for Gd increased the lattice parameters and decreased the Curie temperature from 163 K for x = 0 to 37 K for x = 0.75. A maximum entropy change of 3.82 J/kg K was observed when a 2 T magnetic field was applied to the x = 0 sample. This entropy change decreased with increasing Ce content to 2.04 J/kg K for the x = 0.75 sample.

Fabrication of Potassium Ion Source and its Emission Characteristics

  • Choi, Dae Sun
    • Applied Science and Convergence Technology
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    • v.25 no.6
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    • pp.116-119
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    • 2016
  • In this study, we fabricated the $K^+$ ion source for the various purposes and investigated the emission characteristics. The fabricated $K^+$ ion source was painted in the tungsten filament to make filament type ion source. The RGA spectra show that the filament type $K^+$ ion source has a good out gassing character, so it can be used in the ultra-high vacuum system. The maximum $K^+$ ion current was 20 mA when filament temperature was 1410 K and filament potential was 50 V. When the filament temperature was 1070 K, the initial beam current was 50 mA and decreased only by 2% during 4 hours. The emitting energy was measured to be 2.04 eV. This low value means that the fabricated specimen is a good $K^+$ ion source. We conclude that this filament type ion source can be used in various fields, including the LEIS research.

The Influence of Foreign Aid on Public Sector Efficiency: A Panel Data Analysis

  • Birendra Narayan SHAH
    • The Journal of Economics, Marketing and Management
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    • v.11 no.3
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    • pp.25-35
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    • 2023
  • Purpose: This paper examines whether foreign aid influences public sector efficiency in policy areas of administration, education, and stability. Research design, data and methodology: The study uses panel data of 77 aid recipient developing countries over the period 2000-2020 and employs various panel data techniques to estimate. Results: We found that a percentage change in foreign aid increases administrative efficiency by 0.02 to 0.04 on average ceteris paribus in the short run. On the other hand, a percentage increase in foreign aid decreases education efficiency by 0.005 to 0.006 on average. While the impact of foreign aid on the policy area of stability is insignificant. Conclusions: The empirical results of this study have important implications for both donors and aid recipient countries. It suggests that to get positive influence from foreign aid, in the area of education and stability, the recipient countries need to increase accessibility of secondary schools with quality education especially; technical and vocational. Also, the donor should provide a minimum threshold amount of foreign aid to developing countries for reforming the institutions' capacity building.

A Study on the Parameter Determination of Crustal Movement by Geodetic Technique (측지학적 방법에 의한 지각변동 매개변수 결정에 관한 연구)

  • 조규전;정의환
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.19 no.4
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    • pp.405-414
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    • 2001
  • Plate tectonics is a dominant paradigm in modern geophysics. Because of its geological mechanism, Korea has a possibility of earthquake according to plate motion. Besides the disaster of earthquake grows rapidly, the importance of recognition for earthquake has been emphasized. This study attempts to decide crustal movement parameters with GPS data, analysed baseline after processing data with GIPSY-OASIS II S/W, observed from 6 stations in and around the Korean peninsula, and obtained from selected 11 stations in Korea. As a results, maximum shear strain was $0.04{\mu}/yr$ and the mean azimuth of the maximum compression axes$(A_{z2})$ is estimated as $97.75^{\circ}$ in and around the Korean peninsula. The average rate of the maximum shear strain($({\gamma}_max)$) is $0.17{\mu}/yr$. The mean azimuth of the maximum compression axes$(A_{z2})$ is estimated as $70.25^{\circ}$ in Korea. Such a pattern of strain distribution is harmonious with that of seismic activity in Korea both historically as well as today.

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Ketone ester supplementation of Atkins-type diet prolongs survival in an orthotopic xenograft model of glioblastoma

  • Hassan Azari;Angela Poff;Dominic D'Agostino;Brent Reynolds
    • Anatomy and Cell Biology
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    • v.57 no.1
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    • pp.97-104
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    • 2024
  • Heavy reliance on glucose metabolism and a reduced capacity to use ketone bodies makes glioblastoma (GBM) a promising candidate for ketone-based therapies. Ketogenic diet (KD) is well-known for its promising effects in controlling tumor growth in GBM. Moreover, synthetic ketone ester (KE) has demonstrated to increase blood ketone levels and enhance animal survival in a metastatic VM-M3 murine tumor model. Here, we compared the efficacy of a KE-supplemented Atkins-type diet (ATD-KE) to a classic KD in controlling tumor progression and enhancing survival in a clinically relevant orthotopic patient-derived xenograft GBM model. Our findings demonstrate that ATD-KE preserves body weight (percent change from the baseline; 112±2.99 vs. 116.9±2.52 and 104.8±3.67), decreases blood glucose (80.55±0.86 vs. 118.6±9.51 and 52.35±3.89 mg/dl), and increases ketone bodies in blood (1.15±0.03 mM vs. 0.55±0.04 and 2.66±0.21 mM) and brain tumor tissue (3.35±0.30 mM vs. 2.04±0.3 and 4.25±0.25 mM) comparable to the KD (results presented for ATD-KE vs. standard diet [STD] and KD, respectively). Importantly, the ATD-KE treatment significantly enhanced survival compared to the STD and was indistinguishable from the KD (47 days in STD vs. 56 days in KD and ATD-KE), suggesting that a nutritionally balanced low carbohydrate ATD combined with KE may be as effective as the KD alone in reducing brain tumor progression. Overall, these data support the rationale for clinical testing of KE-supplemented low-carb diet as an adjunct treatment for brain tumor patients.

Variation on Estimated Values of Radioactivity Concentration according to the Change of the Acquisition Time of SPECT/CT (SPECT/CT의 획득시간 증감에 따른 방사능농도 추정치의 변화)

  • Kim, Ji-Hyeon;Park, Hoon-Hee;Lee, Joo-Young
    • Journal of radiological science and technology
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    • v.44 no.6
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    • pp.645-653
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    • 2021
  • With the recent development of precision medicine(Theranostics), interest and utilization of the quantitative function of SPECT/CT are increasing. This study aims to investigate the effect on the radioactivity concentration estimate by the increase or decrease in the total time of SPECT/CT imaging conditions. A standard image was obtained by the conditions of a total acquisition time of 600 sec(10 sec/f × 120 frames) by diluting 99mTc 91.76 MBq in a cylindrical phantom filled with sterile water, and a comparative image was obtained by increasing the total acquisition time by -90%, -75%, -50%, -25%, +50%, +100%. The CNR, radioactive concentration estimate(cps/ml), and the variation rate(%) of the recovery coefficient(RC) were analyzed by measuring the overall coefficient of interest in each image. The results[CNR, Radiation Concentration, RC] by the change in the number of projections for each increase or decrease rate(-90%, -75%, -50%, -25%, +50%, +100%) of total acquisition time are as follows. [-89.5%, +3.90%, 1.04] at -90%, [-77.9%, +2.71%, 1.03] at -75%, [-55.6%, +1.85%, 1.02] at -50%, [-33.6%, +1.37%, 1.01] at -25%, [-33.7%, +0.71%, 1.01] at +50%, [+93.2%, +0.32%, 1.00] at +100%. and also The results[CNR, Radiation Concentration, RC] by the acquisition time change for each increase or decrease rate(-90%, -75%, -50%, -25%, +50%, +100%) of total acquisition time are as follows. [-89.3%, -3.55%, 0.96] at -90%, [-73.4%, -0.17%, 1.00] at -75%, [-49.6%, -0.34%, 1.00] at -50%, [-24.9%, 0.03%, 1.00] at -25%, [+49.3%, -0.04%, 1.00] at +50%, [+99.0%, +0.11%, 1.00] at +100%. Image quality(CNR) showed a pattern of change in proportion to the increase or decrease in the total acquisition time of SPECT/CT, but the result at quantitative evaluation showed a change of less than 5% in all experimental conditions, maintaining quantitative accuracy(RC less than 0.05) without much influence.

The Factors Influencing Intention to Use Emergency Contraceptives Pills For Nursing Students (간호대학생의 응급피임약 사용의도에 영향을 미치는 요인)

  • Kim, Mi-Heyi;Kim, Hye-Jin
    • Journal of Digital Convergence
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    • v.20 no.3
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    • pp.549-556
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    • 2022
  • This study is a descriptive research study to analyze factors affecting their intention to use emergency contraceptive pills for nursing students. Data collected using the online questionnaire for 195 nursing students located in J province from February 3, 2021, to February 25, 2021. Data were analyzed using SPSS 22.0, and the analyses included descriptive statistics, independent t-test, ANOVA, Pearson's correlation coefficient test, and multiple regression. As a result, the average knowledge about emergency contraceptive pills was 6.78±2.46 out of a total of 12 points, the average attitude 3.04±0.64 out of a total of 5 points, and the average intention to use 4.30±0.90 out of a total of 5 points. These factors were significant predictors of Intention to use emergency contraceptives pills and accounted for 13.4% of the variance. In conclusion, it is necessary to develop an education program for emergency contraceptives in order to prevent unnecessary treatment through appropriate use of emergency contraceptives pills when necessary. And a study to verify the effectiveness of the educational program is suggested.

A Case Study of Coastal Fog Event Causing Flight Cancellation and Traffic Accidents (항공기 결항과 연쇄 교통사고를 야기한 연안안개 사례 연구)

  • Kim, Young Chul
    • Journal of the Korean Society for Aviation and Aeronautics
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    • v.25 no.1
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    • pp.1-10
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    • 2017
  • A heavy foggy event accompanying with complex coastal fog was investigated in this study. This heavy foggy event occurred on FEB 11, 2015. Due to reduced visibility with this foggy event induced more than 100times serial traffic accidents over the Young-jong highway, and Flights from 04:30 AM to 10:00 AM were cancelled on Inchon International Airport. This heavy foggy event was occurred in synoptic and mesoscale environments but dense coastal fog were combined with a combination of sea fog, steam fog, and radiation fog. This kind of coastal fog can predicted by accurate analysis of the direction of the air flow, sea surface temperature(SST), and 925hPa isotherms from numerical weather prediction charts and real time analysis charts.