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Blood Lead Concentration Correlates with All Cause, All Cancer and Lung Cancer Mortality in Adults: A Population Based Study

  • Cheung, Min Rex
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.5
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    • pp.3105-3108
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    • 2013
  • Background: This study used National Health and Nutrition Examination Survey III to study the relationship between blood lead concentration and all cause, all cancer and lung cancer mortality in adults. Patients and Methods: Public use National Health and Nutrition Examination Survey (NHANES III) data were used. NHANES III uses stratified, multistage probabilistic methods to sample nationally representative samples. Household adult, laboratory and mortality data were merged. Sample persons who were available to be examined in aMobile Examination Center (MEC) were included in this study. Specialized survey analysis software was used. Results: A total of 3,482 sample participants with complete information for all variables were included in this analysis. For all cause death, the odds ratios (S.E.) for statistically significant variables were body mass index, 1.03 (1.01-1.06); 1.01 (1.01-1.01); blood lead concentration, 1.05 (1.01-1.08); poverty income ratio, 0.823 (0.76-0.89); and drinking hard liquor, 1.01 (1.00-1.02). For all cancer mortality, the odds ratios (S.E.) of the statistically signigicant variables were: age, 1.01 (1.01-1.01); blood lead concentration, 1.07 (1.04-1.12), black race, using non-Hispanic white as reference, 1.69 (1.12-2.56); and smoking, 1.02 (1.01-1.04). For lung cancer mortality, the odds ratios (S.E.) of the statistically significant variables were: age, 1.01(1.01-1.01); blood lead concentration, 1.09 (1.05-1.13); Mexican Americans, using non-Hispanic white as refrence, 0.33 (0.129-0.850); other races, 1.80 (0.53-6.18); and smoking, 1.03 (1.02-1.05). Conclusion: Blood lead concentration correlated with all cause, all cancer, and lung cancer mortality in adults.

Occurrence and Chemical Composition of White Mica from Zhenzigou Pb-Zn Deposit, China (중국 Zhenzigou 연-아연 광상의 백색운모 산상과 화학조성)

  • Yoo, Bong Chul
    • Korean Journal of Mineralogy and Petrology
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    • v.35 no.2
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    • pp.83-100
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    • 2022
  • The Zhenzigou Pb-Zn deposit, which is one of the largest Pb-Zn deposit in the northeast of China, is located at the Qingchengzi mineral field in Jiao Liao Ji belt. The geology of this deposit consists of Archean granulite, Paleoproterozoinc migmatitic granite, Paleo-Mesoproterozoic sodic granite, Paleoproterozoic Liaohe group, Mesozoic diorite and Mesozoic monzoritic granite. The Zhenzigou deposit which is a strata bound SEDEX or SEDEX type deposit occurs as layer ore and vein ore in Langzishan formation and Dashiqiao formation of the Paleoproterozoic Liaohe group. White mica from this deposit are occured only in layer ore and are classified four type (Type I : weak alteration (clastic dolomitic marble), Type II : strong alteration (dolomitic clastic rock), Type III : layer ore (dolomitic clastic rock), Type IV : layer ore (clastic dolomitic marble)). Type I white mica in weak alteration zone is associated with dolomite that is formed by dolomitization of hydrothermal metasomatism. Type II white mica in strong alteration zone is associated with dolomite, ankerite, quartz and alteration of K-feldspar by hydrothermal metasomatism. Type III white mica in layer ore is associated with dolomite, ankerite, calcite, quartz and alteration of K-feldspar by hydrothermal metasomatism. And type IV white mica in layer ore is associated with dolomite, quartz and alteration of K-feldspar by hydrothermal metasomatism. The structural formulars of white micas are determined to be (K0.92-0.80Na0.01-0.00Ca0.02-0.01Ba0.00Sr0.01-0.00)0.95-0.83(Al1.72-1.57Mg0.33-0.20Fe0.01-0.00Mn0.00Ti0.02-0.00Cr0.01-0.00V0.00Sb0.02-0.00Ni0.00Co0.02-0.00)1.99-1.90(Si3.40-3.29Al0.71-0.60)4.00O10(OH2.00-1.83F0.17-0.00)2.00, (K1.03-0.84Na0.03-0.00Ca0.08-0.00Ba0.00Sr0.01-0.00)1.08-0.85(Al1.85-1.65Mg0.20-0.06Fe0.10-0.03Mn0.00Ti0.05-0.00Cr0.03-0.00V0.01-0.00Sb0.02-0.00Ni0.00Co0.03-0.00)1.99-1.93(Si3.28-2.99Al1.01-0.72)4.00O10(OH1.96-1.90F0.10-0.04)2.00, (K1.06-0.90Na0.01-0.00Ca0.01-0.00Ba0.00Sr0.02-0.01)1.10-0.93(Al1.93-1.64Mg0.19-0.00Fe0.12-0.01Mn0.00Ti0.01-0.00Cr0.01-0.00V0.00Sb0.00Ni0.00Co0.05-0.01)2.01-1.94(Si3.32-2.96Al1.04-0.68)4.00O10(OH2.00-1.91F0.09-0.00)2.00 and (K0.91-0.83Na0.02-0.01Ca0.02-0.00Ba0.01-0.00Sr0.00)0.93-0.83(Al1.84-1.67Mg0.15-0.08Fe0.07-0.02Mn0.00Ti0.04-0.00Cr0.06-0.00V0.02-0.00Sb0.02-0.01Ni0.00Co0.00)2.00-1.92(Si3.27-3.16Al0.84-0.73)4.00O10(OH1.97-1.88F0.12-0.03)2.00, respectively. It indicated that white mica of from the Zhenzigou deposit has less K, Na and Ca, and more Si than theoretical dioctahedral mica. Compositional variations in white mica from the Zhenzigou deposit are caused by phengitic or Tschermark substitution [(Al3+)VI+(Al3+)IV <-> (Fe2+ or Mg2+)VI+(Si4+)IV] substitution. It means that the Fe in white mica exists as Fe2+ and Fe3+, but mainly as Fe2+. Therefore, white mica from layer ore of the Zhenzigou deposit was formed in the process of remelting and re-precipitation of pre-existed minerals by hydrothermal metasomatism origined metamorphism (greenschist facies) associated with Paleoproterozoic intrusion. And compositional variations in white mica from the Zhenzigou deposit are caused by phengitic or Tschermark substitution [(Al3+)VI+(Al3+)IV <-> (Fe2+ or Mg2+)VI+(Si4+)IV] substitution during hydrothermal metasomatism depending on wallrock type, alteration degree and ore/gangue mineral occurrence frequency.

Cytotoxic Effect of X-irradiation of Mouse Tumor Cells in the Presence of Korean Ginseng Extract (마우스 종양세포의 세포독성에 미치는 인삼 추출액과 방사선조사의 병용 효과)

  • Kwon Hyoung-Cheol;Kim Jin-Ki;Kim Jung-Soo;Choi Dong-Seong
    • Radiation Oncology Journal
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    • v.18 no.3
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    • pp.200-204
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    • 2000
  • Purpose : We already reported the results that aqueous extract of Korean ginseng roots showed a marked cytotoxicity. In this study, we investigated whether combined ginseng product with X-irradiation increase the cytotoxicity of tumor cells than X-irradiation or not. Materials and Methods : Fifty gram of Korean ginseng powder mixed with 1 L of distilled water was extracted with reflux flask under condition of $100^{\circ}C$ for 5 hrs. This aquaous ginseng extract was filtered, centrifuged and then was freezed under condition of $-90^{\circ}C$ for 16-18 hrs. The freezing extract was dried with freeze drier, and then diluted. X-irradiation was given to tumor cells by 6 MeV linear accelerator. The cytotoxicity of ginseng in vitro was evaluated from its ability to reduce the clonogenecity of fibrosarcoma (FSa II) cells. In X-irradiation alone group, each 2, 4, 6 and 8 Gy was given to tumor cells. In X-irradiation with ginseng group, 0.2 mg/mL of ginseng extract was exposed to tumor cells for 1 hour before X-irradiation. Results : The yield for 50 g of ginseng extract which was treated with freezing drier was 3.13 g($6.3\%$). Cytotoxicity In vitro was measured as survival fraction which was judged from the curve, at ginseng concentration of 0.001, 0.01, 0.1 and 1 mg/mL were $0.89\pm0.04$, $0.86\pm0.06$, $0.73\pm0.01$ and $0.09\pm0.02$, respectively. Survival fraction at X-irradiation alone of 2, 4, 6 and 8 Gy were $0.81\pm0.07$, $0.42\pm0.08$, $0.15\pm0.02$, $0.03\pm0.01$, respectively. But, suwival fraction in combined group of X-irradiation and ginseng (0.2mg/ml) at each same radiation dose were $0.28\pm0.01$, $0.18\pm0.03$, $0.08\pm0.02$, $0.006\pm0.002$, respectively (p<0.05). Conclusion : The yield for ginseng extract which was treated with freezing drier was $6.3\%$. Cytotoxicty of Fsa 11 in combined ginseng with X-irradiation group was increased than that of X-irradition alone group, and its enhancing effect seemed to be added.

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Oral symptoms experienced by adolescents based on Body Mass Index (체질량지수에 따른 청소년의 구강증상 경험)

  • Kim, Young-Suk
    • Journal of the Korea Convergence Society
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    • v.12 no.3
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    • pp.317-323
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    • 2021
  • The purpose of this study was to analyze the oral symptoms experienced by adolescents according to Body Mass Index. We analyzed the data using the Korea Youth Risk Behavior Web-based Survey and conducted complex-sample descriptive statistics on 55,728 participants. The prevalence of sensitive teeth, tooth pain, gingival bleeding, and swelling was highest in the overweight group (36.8%, 23.9%, and 19.2%) and lowest in the underweight group (34.6%, 20.8%, and 17.0%) (p<0.001). Tooth pain, gingival bleeding, and swelling were significantly higher (all 1.08) in the overweight group than in the normal group. Halitosis was 1.19-and 1.43-higher in the overweight and obese groups, respectively. The relationship between systemic diseases and oral health among adolescents should be further investigated.

Validation of the Need for Closure Scale-Short Form (단축형 종결 욕구의 타당화)

  • Kim, Eunkyung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.10
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    • pp.166-173
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    • 2020
  • The purpose of the present study was to validate the Need for Closure Scale-Short Form (NFCS-SF), which measures the need for cognitive closure. Participants completed questionnaires regarding need for cognitive closure, intolerance of uncertainty, depression, and anxiety. Of the 536 data collected between May and July 2017, data from a total of 495 participants were analyzed using SPSS 20.0 and M-Plus. The results of the study are as follows. First, a 15-item selection comprised three items from each facet scale via exploratory factor analysis. Second, the NFCS-SF demonstrated good internal consistency (Study 1, Cronbach's α=.85; Study 2, Cronbach's α=.84). Third, the results of the confirmatory factor analyses supported a 5-factor model (χ2(80)=178.34, p<.001; CFI=.87, TLI=.83, RMSEA=.07, SRMR=.08). Fourth, the NFCS-SF showed significant correlation with the measures of intolerance of uncertainty (r=.58, p<.01), depression (r=.16, p<.05), and anxiety (state anxiety, r=.31, p<.01; trait anxiety, r=.29, as well as the NFCS (r=.86, p<.01). Based on these findings, significance and limitations of the results as well as suggestions for further study are discussed.

Inorganic and Organic Geochemical Characteristics of Devonian Bitumen Carbonate in Alberta, Canada (캐나다 데본기 비투멘 탄산염암의 무기 및 유기 지화학적 특성 연구)

  • Choi, Ji-young;Kim, Ji-Hoon;Kil, Yong-Woo;Lee, Sung-Dong;Park, Myong-Ho
    • Economic and Environmental Geology
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    • v.44 no.1
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    • pp.21-35
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    • 2011
  • Inorganic and organic geochemical characteristics of Devonian bitumen carbonates in Alberta were studied using two drilling cores, Saleski 03-34-88-20w4 and Saleski 08-01-88-20w4, taken from the Core Research Center of Canada. The results of elements analyses showed high Total Inorganic Carbon, low Total Nitrogen and Total Sulfur, and Rock-Eval pyrolysis showed double $CO_2$ peaks in the oxidation part. These mean that the Devonian bitumen carbonates are mainly composed of dolomite formed by diagenesis, and its crystal texture is dominantly subhedral to anhedral but often euhedral. Bitumen contents were 3.6~19.0% in Saleski 3-34-88-20w4 and 5.0~16.4% in Saleski 08-01-88-20w4, respectively. As samples color become dark, bitumen and Total Organic Carbon contents are generally increasing in two cores. The results of biomarker analyses showed that the contents of resins and asphaltenes were 5~28% higher than those of saturated hydrocarbon, interring that the bitumen has been heavily biodegradated. According to the results of carbon isotope analyses in each component of bitumen, asphaltenes had highest values and the others had constant values. However, their values were varied in the range of normal crude oil (-18~-30‰).

Effects of Long-distance Horseback Riding on Blood Lipid, Adipokine, Inflammatory Marker in Obese Middle Aged Women

  • Lee, Jin-Wook;Park, Jong-Hwa
    • Journal of the Korea Society of Computer and Information
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    • v.27 no.8
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    • pp.185-194
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    • 2022
  • The purpose of this study was to verify the effects of long-distance horseback riding on blood lipid, adipokines and inflammatory markers in obese middle-aged women. The subjects of this study were 9 obese meddle aged women and the data analysed using the paired t-test. The result of this study were as follows: First, TC(p<.01), LDL-C(p<.01), and HDL-C(p<.001) were significantly increased after long-distance horseback riding(LDHR). Second, adiponectin was significantly increased(p<.01) and also PAI-1 was significantly decreased(p<.01) after LDHR. Third, IL-6 was significantly increased(p<.01) after LDHR. These results suggest that long-distance horseback riding has positive effect on changes blood lipid, adipokines, and inflammatory markers in obese middle-aged women. Therefore we consider that effects of long-distance horseback riding has partial examine on prevention and therapy of obesity in middle-aged obese women who undergo physical and emotional big changed.

The Effects of Breath Alcohol Concentration Increase on Visual Field and Readable Visual Field (호흡 알코올 농도 증가가 시야 및 가독시야에 미치는 영향)

  • Jung, Su A;Nam, Soo-Kyung;Kim, Hyun Jung
    • Journal of Korean Ophthalmic Optics Society
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    • v.21 no.2
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    • pp.153-158
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    • 2016
  • Purpose: This study was aimed to investigate effects of breath alcohol concentration (BrAC) increase on visual field and readable visual field. Methods: 23 males in 20s (average age $21.17{\pm}2.19years$, body mass index (BMI) $22.09{\pm}2.16$) were selected and administered the amount of alcohol to reach 0.05% and 0.08% BrAC calculated by BAC (blood alcohol concentration) Dosing Software program. Then, visual field and readable visual field test with Vision Disk were conducted. Results: Visual field are measured as $74.41{\pm}15.97^{\circ}$, $64.98{\pm}17.93^{\circ}$, and $58.33{\pm}19.01^{\circ}$ (p=0.000) and readable visual field as $21.93{\pm}12.71^{\circ}$, $17.41{\pm}11.36^{\circ}$, $14.26{\pm}9.93^{\circ}$ (p=0.006) in 0.00%, 0.05% and 0.08% BrAC respectively. As breath alcohol concentration increased, both visual field and readable visual field decreased. Conclusions: BrAC increase with drinking could be the cause of safety accident by decreasing visual field and readable visual field, it is necessary to raise awareness.

A Study of Nurses Burden and Attitude on Terminal Cancer Patients (말기암 환자에 대한 간호사의 부담감과 태도 연구)

  • Kim, Yun-Hee
    • Asian Oncology Nursing
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    • v.1 no.1
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    • pp.65-74
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    • 2001
  • This study was to investigate the degree of the nurses' burden and the attitude on the terminal cancer patients, as well as the relationship between two variables using questionnaire. The non-randomized convenient samples were 252 nurses with the experiences in caring the terminal cancer patients more than 1year in 5 university hospitals in Seoul and Inchon city. The cross-sectional one time survey was conduced by using the modified questionnaires on the burden and the attitude on the terminal cancer patients at October, 2000. n SPSS for Window, the demographic information and the degree of the burden and the attitude of subjects were analyzed with descriptive statistics. Pearson correlation coefficiency was used to investigate the relationship between the degree of the burden and the attitude from subjects. The additional analysis were performed to examine the differences the degree of the burden and the attitude by the general characteristics of the nurses using t-test and ANOVA. The result was as follow: 1) The degree of the nurses' burden on the terminal cancer patients was the mean of 2.91 ranged from 2.08 to 3.96. 2) The degree of the nurses' attitude on the terminal cancer patients was the mean of 3.52 ranged from 1.83 to 4.68. 3) There was no significant relationship between the degree of the burden and the attitude on the terminal cancer patients(r=.08, p=.23). However, the burden and. the nursing environment among 4 aspects of the attitude showed a significantly positive relationship each other (r=.16, p=.01). 4) The degree of the nurses' burden was different by the nursing specialties (F=2.79, p=.03) and the professional perspectives on nursing(F=3.52, p=.02). 5) The degree of the nurses' attitude was different by the age(F=5.33, p=.01), the married status(t=3.93, p=.05), nursing specialties (F=7.42, p=.00), the amount clinical experience(F=2.85, p=.04), the job satisfaction (F=10.58, p=.00) and, the professional perspectives on nursing (F=6.30, p=.01).

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Effects of Aquarobics on Metabolic Syndrome and Health Fitness in Abdominally Obese Elderly Women (아쿠아로빅 운동이 복부비만 노인여성의 대사증후군 및 건강체력에 미치는 영향)

  • Park, Young-Ah;Kim, Dong-Hee
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.8
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    • pp.5180-5188
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    • 2015
  • The purpose of this study was to investigate the effects of a 12-weeks aquarobics on metabolic syndrome risk factors and health fitness in 25 abdominally obese elderly women. As the results, while waist circumference(87.40/82.76cm, p<.01) decreased, HDL-C(41.13/45.42mg/dl, p<.05) increased after the exercise program. Blood pressure and TG, however, decreased with no significance. And while muscle strength increased(17.06/19.08kg, p<.05), the increase in flexibility, muscle endurance, and cardiopulmonary endurance and the decrease in body fat showed some positive effects of the exercise program. In conclusion, we found that the aquarobics improves the aging-induced deterioration in the muscular skeletal function by lowering abdominal obesity and improving metabolic syndrome and physical fitness for health. In addition, the aquarobics can be an effective alternative to an aerobics or a resistance exercise on the ground.