• Journal of Advanced Navigation Technology
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• v.14 no.4
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• pp.562-570
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• 2010

The transmission phenomenon of neuron action potential due to exterior stimulation is somewhat identical to electrical reaction configuration. Therefore, I tried to analyze the transmission status of membrane excitation, by introducing electrical concept to this issue in this paper. First of all, I researched the complex electrical status of axon, and then simplified the electrical circuit into pure resistance circuit under the assumption that it was reasonable in practice. And I derived the transmission status of exciting action potential through the simplified circuits using electical theory and mathematical concept. I calculated overshoot potential of a certain portion and then confirmed that it excited neighbor portion and made it to be transmitted using the proposed data which was typical in point of biological and electrical view to verify this result.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1992.05a
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• pp.37-37
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• 1992

세포의 흥분성과 막전위의 조절에 있어서 $K^{+}$ channel의 역할이 크다는 사실이 인정 됨으로서 (Rudy, 1988) $K^{+}$ channel 개방 약물의 약리학적 연구와 임상적 응용에 대한 관심은 높아졌다. Cromakalim, nicorandil 및 pinacidil등이 혈관 평활근을 특히 예민하게 이완시킨다. 작용기전으로서는 세포의 원형질 막을 통한 $K^{+}$ 전도의 항진과 $K^{+}$ outward current의 증가가 막 과분극을 일으킨다. 이러한 결과는 막흥분에 의한 voltage-dependent $Ca^{++}$ channel을 닫게하고 세포내 free $Ca^{++}$의 농도를 감소시켜 혈관의 흥분성과 수축력의 감소를 야기하여 근이완을 야기한다. 한편, 평활근 세포막의 $Na^{+}$-$K^{+}$ ATPase도 활성화하면 electrogenic pump를 가동하여 막 과분극을 일으키고 막 흥분성을 저하시킨다. $Na^{+}$-$K^{+}$ pump는 세포 바깥의 $K^{+}$과 세포안의 $Na^{+}$농도에 의하여 활성화한다.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1978.06a
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• pp.9.1-10
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• 1978

Recently the authors have observed various wave-forms by insertion of induction coil into the scala tympani as well as attached outer device in the outside of the body in damaged hair cells of the cats. In the cochlear nerve. action potential indicated different polarities induced by examination of the bundle of the cochlear nerve fibers. Impulse wave-form as a result of excitation of cohlear nerve fibers showed bipolar wave-form such as negative 1 and positive 1. Therefore action potential showed also bipolar wave-form as above mentioned. We can obtained suitable response with above mentioned outer and inner device as an exact oscillogram.

• Journal of Biomedical Engineering Research
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• v.15 no.4
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• pp.481-488
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• 1994

In this paper a study of neuro-pathway estimation based on visual and somatosensory evoked potential is given. The evoked potentials which are caused by visual and somatosensory stimulation are detected by an average method. The forward problem that is estimating a scalp potential from a given electrical source in the brain is solved by using a triple concentric spherical shell model of the head and a single current dipole model of the neuron activity. The inverse problem which calculates a source position is solved by a least square fit between the model predicted potential and a given evoked potential measurement. The similarities between estimated sensory neuro-pathways and physiological brain function regions are verified.

• Journal of Advanced Navigation Technology
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• v.14 no.6
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• pp.1002-1009
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• 2010

I made the axon to the electrical transmission model and then constructed electrical equivalent model using Kirhhoff's current law and voltage law in this paper. I calculated various axon parameters in order to analyze the electrical potential hehavior versus minute distance chang of axon. The transmission velocity of unmyelinated nerve is proportional to square root of axon diameter, while that of myelinated nerve is directly proportional to its diameter. Because the transmission of myelin sheath is independent of voltage unlike unmyelinated sheath, the Hodgkin-Huxley model across the membrane is not so precise.

• Proceedings of the KOSOMBE Conference
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• v.1994 no.12
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• pp.121-123
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• 1994

손가락 움직임과 관련된 운동성 유발전위를 검출하기 위하여 컴퓨터를 이용하여 피검자에게 움직임 명령을 제시하고 명령에 따른 최종적인 피검자의 운동이 나타나는 과정까지의 뇌전위를 검출하는 시스템을 구성하였다. 위와 갊은 실험을 왼손 오른손에 대하여 자각 700번 정도 수행하여 average method를 이용하여 운동성 유발 전위를 검출하고, 신경전류 추적법을 이용하여 뇌의 흥분 뉴런군을 추정하였다.

• Journal of Advanced Navigation Technology
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• v.16 no.4
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• pp.657-664
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• 2012

One of the methods to transmit solute through solvent is diffusion. Various particles or molecules including several charged ions in the body diffuse from high density region to low density due to density difference or external electric field. This kind of mechanism is due to thermal motion of each solute molecules. These situations can be deployed using Fick's first and second laws that govern diffusion phenomena in the body. I analysis these diffusion status of material in the body using above mentioned Fick's laws and then implement them through illustration.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.14 no.12
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• pp.2827-2835
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• 2010

When the inferiorthreshold potential is applied on the membrane, the resting status membrane does not display any specific reaction, in the meanwhile if it receives somewhat higher voltages then it shows entirely different configuration. The fact that there is this kind of characteristics on the exciting membrane has been known for a long time, and some researchers have tried to analyze this situation using the electrical circuits but only limitted to inferiorthreshold potential case. The quantitative studies of especially for transthreshold stimulus is extremely rare up to now. The direct application of electrical circuit to biostatus is somewhat uneasonable because there may be much differences between them. We studied the electrical reaction quantitatively of biomembrane when it receives the transthreshold stimulus in point of electricity in this paper.

• Journal of the Korean Institute of Telematics and Electronics B
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• v.33B no.8
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• pp.22-29
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• 1996

This study describes a method to find the torso surface potential based on the boundary element method. In order to find the torso surface potential, the governing equation was developed based on the green's second theorem. The boundary element method (BEM) which has a good computing capability in case of homogeneous and isotropic medium was applied to solve the equation. to validate the BEM, we considered a homogeneous sphere model which has an electrric dopole source inside. The results showed the good agreement between the analytic solution and the computed solution. In normal heart, the simulated torso surface isopotential maps are good agreement with that obtained form the ventricular excitation.

• Korean Journal of Applied Biomechanics
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• v.19 no.4
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• pp.681-688
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• 2009

To better delineate the changes in corticospinal excitability when older adults are asked to observe and/or imagine actions, 22 right-handed older adults without neurological abnormalities were included in this study. The amplitude and latency of motor evoked potentials (MEPs) by transcranial magnetic stimulation were recorded in the abductor pollicis brevis of the dominant hand during passive observation/imagery/active observation of slow/fast action of abduction of right thumb and also at resting state. Thus, active observation showed better changes than passive, but slow and fast action revealed no difference at all.