• Title/Summary/Keyword: 흡착률

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Formulation of Liquid Choline Alphoscerate as a Solid Dosage Form (액상 콜린알포세레이트의 고형 제제화 연구)

  • Choi, Sung-Up;Cho, Seong-Wan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.12
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    • pp.6324-6329
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    • 2013
  • The aim of this study was to prepare and evaluate tablets containing liquid choline alphoscerate, which is capable of being formulated as a solid dosage form by the adsorption of magnesium aluminum silicate. The tablets were prepared with various absorbent to choine alphoscerate ratios. The physical properties and the dissolution rate were investigated. Considering the tabletting and dissolution rate, the formula scontaining 50-75% absorbent were adequate in the tested formulations. The 62.5% absorbent formula showed superior results with the tests of hardness, friability, disintegration time, and the ratio of dissolution area under the curve. Overall, magnesium aluminum silicate can be an alternative additive to a liquid drug.

Modeling for Evolution of a 3-dimensional Structure on Semiconductor Substrate (반도체 기판 위의 3차원 구조에 대한 형상 진화 모델링 연구)

  • Jung, Hyun-Su;Won, Tae-Young
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.37 no.12
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    • pp.24-28
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    • 2000
  • This paper reports a new calculation method of three dimensional deposeition rate by level set method. To model an advancement of the surface efficiently, we have developed a new iteration method to re-initialize the level set function. For calculating etching and deposition rate by direct flow, we have developed a visibility test module and a refraction and re-sputtering model. Sputter deposition rate with shadow effect and surface refraction is calculated. We report that difference of profiles in cases that sticking coefficient are 1.0 and 0.3. We report that the difference of the deposition rate on bottom of the hole is caused by a difference of visible angle by the shadowing effect.

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A Study of Alkali Metal Vapor Adsorption Behavior by Using Pressurized Reactor (가압반응기를 이용한 알칼리금속증기 흡착특성에 관한 연구)

  • 전수한;최병철;김형택
    • Journal of Energy Engineering
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    • v.11 no.2
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    • pp.114-121
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    • 2002
  • Alkali metal compounds existed in original coal or sorbents are exhausted as vapor or small particle at the outlet of combustor when operating PFBC power plant. These compounds can be removed with dust removal equipment, but total generation efficiency will be decreased because of lower operating temperature of dust removal equipment. Alkali metal contained in vapor phase is initially deposited onto turbine blade results in serious corrosion. The concentration of alkali vapor in the PFBC flue gas is 20∼40 ppm which is dependent on mineral characteristics and composition as well as operating condition of PFBC. However, the allowance limit of alkali metal vapor is assigned as less than 50 ppb for gas turbine when coal or oil is used as fuel. Therefore, alkali metal vapor in PFBC or IGCC process should be removed by solid sorbents to prevent corrosion of turbine blade and improve plant efficiency. In the present investigation, powder of Bauxite, Kaolinite and Limestone is used in the preparation of cylinder-type pellet which is inserted into the pressurized alkali removal reactor for the alkali absorption experiment. Experimental results showed that the alkali removal efficiency in the order of Bauxite, Kaolinite and Limestone. Alkali vapor removal efficiency is related with reaction temperature, porosity of pellet and alkali vapor concentration of flue gas.

A Study on the Prediction of Elastoplastic Behavior of Carbon Nanotube/Polymer Composites (계면 결합력과 나노튜브의 응집에 따른 나노튜브/고분자 복합재의 탄소성 거동 예측에 대한 연구)

  • Yang, Seunghwa;Yu, Suyoung;Ryu, Junghyun;Cho, Maenghyo
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.26 no.6
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    • pp.423-430
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    • 2013
  • In this research, a paramteric study to account for the effect of interfacial strength and nanotube agglomeration on the elastoplastic behavior of carbon nanotube reinforced polypropylene composites is performed. At first, the elastoplastic behavior of nanocomposites is predicted from molecular dynamics(MD) simulations. By combining the MD simulation results with the nonlinear micromechanics model based on the Mori-Tanaka model, a two-step domain decomposition method is applied to inversely identify the elastoplastic behavior of adsorption interphase zone inside nanocomposites. In nonlinear micromechanics model, the secant moduli method combined with field fluctuation method is used to predict the elastoplastic behavior of nanocomposites. To account for the imperfect material interface between nanotube and matrix polymer, displacement discontinuity condition is applied to the micromechanics model. Using the elastoplastic behavior of the adsorption interphase zone obtained from the present study, stress-strain relation of nanocomposites at various interfacial bonding condition and local nanotube agglomeration is predicted from nonlinear micromechanics model with and without the adsorption interphase zone. As a result, it has been found that local nanotube agglomeration is the most important design factor to maximize reinforcing effect of nanotube in elastic and plastic behavior.

Studies on the Immobilization of Lipase by Adsorption Method (흡착법에 의한 Lipase의 고정화)

  • Park, Jong-Hack;Lee, Young-Chun
    • Korean Journal of Food Science and Technology
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    • v.17 no.2
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    • pp.75-80
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    • 1985
  • To utilize lipase obtained from Candida cylindracea for lipid hydrolysis, methods to immobilize lipase by adsorption and reaction characteristics of the immobilized lipase by adsorption were investigated. Among the tested adsorbents, silica gel was selected as a suitable adsorbent. The optimum condition for adsorption of lipase was when 47.5 units of lipase were adsorbed to 1.6g of silica gel at pH7.0 and $5^{\circ}C$ for 100 min. Optimum pH and temperature for activity of the immobilized lipase were at $37^{\circ}C$ and pH7.0, which were same as the soluble lipase. Optimum enzyme concentration of the immobilized lipase were 30g for milk fat and 80g for olive oil, whereas those of the soluble lipase were 800 units for milk fat and 1200 units for olive oil. The optimum substrate concentrations of the immobilized and soluble lipases were 20% lipid, regardless of lipid types. Rapid hydrolysis of milk fat was observed with the soluble lipase for the initial 4 hours and with the immobilized lipase for the initial 8 hours. The immobilized lipase produced same amount of capric acid as the soluble lipase, but more myristic acid and less butyric acid than the soluble lipase.

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Particle Transport of Residual Soils (풍화잔적토의 유동특성에 대한 연구)

  • 이인모;박광준
    • Geotechnical Engineering
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    • v.13 no.5
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    • pp.155-168
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    • 1997
  • The phenomena of detachment and movement of One particles are one of the important mechanisms both in geotechnical and geoenvironmental engineering. In geoenvironmental engineering, in particular, movement of fine particles may facilitate the transport of contaminants since the particle surfaces absorb contaminants before movement. Weathered granitic residual soils, which are the most abundant in Korea. contain large quantities of fine particles up to 50%. The characteristics of fine particle movement of weathered granitic residual soils are investigated in this paper. Samples are obtained from Poiiong, Shinnaedong in Seoul and Andong in Kyungpook : each of the samples represents typical residual soil types in Korea. Laboratory experiments for the three adopted soil types are performed. It is found that effluent concentration of the samples is influenced by porosity, fine particle percentage and particle size distribution. The critical velocity decreases as the fine particle percentage increases and the rate of change of erosion rate increases as the porosity increases. And well-graded samples showed less effluent concentrations compared to poorly-graded samples. The governing equation on the physical mechanism of fine particle movement and its nomerical solution scheme are suggested on the basis of the test results.

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A Two-dimensional Numerical Simulation of Cohesive Sediment Transport in the Mokpo Coastal Zone (목포해역의 점착성 퇴적물 이동에 관한 2차원 수치모의)

  • Choi, Jong-Hwa;Jung, Tae-Sung
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.24 no.4
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    • pp.287-294
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    • 2012
  • Sedimentary environment in coastal zone has been changing due to a large number of coastal structures and continuous coastal development. As a result, the environment has been changing. In particular, the economic and environmental damage can occur due to cohesive sediment transport closely related with the fate of pollutants. Due to large sea wall construction the ebb dominance in the Mokpo coastal waters has been clearer. Cohesive sediment transport was simulated by the EFDC model. The simulated SS showed good agreements with the observed SS. From the sensitivity analysis of sediment parameters, we found out that the erosion rate, the critical shear stresses for erosion and deposition, and the settling velocity are important factors in cohesive sediment transport modeling.

Saccharification Characteristics and Kinetic Analysis of Modified Cellulase with a Copolymer (공중합 고분자를 이용한 수식셀룰라아제의 당화 특성 및 반응속도에 관한 연구)

  • 전영호;신호철박진원
    • KSBB Journal
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    • v.11 no.6
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    • pp.712-717
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    • 1996
  • Cellulase was modified with synthetic copolymers of polyoxyethylene derivative and maleic acid anhydride. The saccharification characteristics and enzymatic reaction kinetic mechanism of modified and native cellulases were observed. In modification reaction of cellulase, degree of modification(DM) increased, as mass ratio of copolymers to enzyme increased. Maximum DM was 55% at mass ratio of 4 and remained activity was 75%. In saccharification experiment modified enzyme had maintained higher stability than native enzyme over all the reaction and the final conversion yield of modified enzyme was greater than that of native enzyme. Numerical simulation based on the reaction mechanism considering enzymatic deactivation was performed. Modified enzyme had kept higher free enzyme concentration over all the reaction than that of native enzyme. Comparing calculation values with experimental data, calculation values were in accordance with experimental data.

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Effects of the Preparing Conditions on the Physical Properties of Surface Grown UHMW PE Fibers (표면성장 폴리에틸렌 섬유의 제조조건이 그물리적 성질에 미치는 영향)

  • 김상용
    • The Korean Journal of Rheology
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    • v.4 no.1
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    • pp.52-61
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    • 1992
  • 초고분자량 폴리에틸렌을 파라 크실렌에 녹인 희박 용액에 전단흐름을 가해 섬유를 뽑아내는 방법에 대해 연구하였다. 표면성장이라 불리는 이 방법을 용액내에서 회전하는 rotor 의 표면에 흡착된 젤 층에, 결정성이 강한씨(seed)를 접촉시킴으로써 엉킨 분자쇄들이 전단력에 의해 신장되어 분자의 자유에너지가 증가하도록 하여 연속적으로 고강력, 고탄성 률 결정을 뽑아내게 한 것이다. 이표면성장법으로 섬유를 얻는데 있어서 결정화온도 rotor 속도, 권취속도 및 고분자 농도와 같은 결정화 변수를 변화시키면서 섬유의 물리적 성질에 미치는 영향을 관찰하였다. 이방법으로 섬유를 성장시키면 열역학적 평형온도(118.6$^{\circ}C$) 이상 인 12$0^{\circ}C$에서 성장시켰을 때 133GPa의 인장 탄성계수 3.1%의 절단신도에서 5.04GPa의 고 강력을 갖는 섬유를 얻을수 있었다. 또한 이방법에 있어서는 결정화 온도가 물리적 성질에 가장 큰 영향을 미치는 인자로 작용하였다, 고분자 농도의 영향은 0.7wt.% 이상에선 물리적 성질이 더 이상 개선되지 않았으며 오히려 장력의 증가로 불안정한 성장을 보였다. 또한 0.5wt%이하에서는 젤층의 형성이 둔화됨을 볼수 있었다. 결국 물리적 성질의 측면에서 볼 때 0.5~0.7wt%에서 최적조건을 보여주었다.

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원전 출력감발 운전에 따른 방사성 부식생성물 거동 분석

  • 성기방
    • Proceedings of the Korean Nuclear Society Conference
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    • 1996.11a
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    • pp.103-109
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    • 1996
  • 고리 원자력 1호기 14주기(‘95년도) 운전기간 중 증기발생기 세관 열전달 용량 저하로 전출력 운전 기간동안 정격출력보다 15% 감발 운전한 경험이 있었는데, 이 기간중 냉각재내 방사성 부식생성물(CRUD) 농도가 약 80% 감소됨을 발견하였다. 이때 출력감소 비율보다 많은 CRUD 감소현상 규명을 위해 냉각재 수질관리인자와 EPRI 피복재 부식모델인 PFCC코드를 사용한 피 복재 산화물 두께변화 등을 비교한 결과, 운전중 용출되는 방사성 부식생성물은 핵연료 표면의 피복재 산화물에 흡착된 Co핵종이 피복재 산화물 이탈시 함께 거동하는 것으로 확인되었으며, 피복재 산화물 이탈은 산화막 두께 및 열유속에 주로 의존함이 밝혀졌다. 따라서 냉각재내에서 방사성 부식 생성물의 생성률 저감을 위해서는 정상운전시 핵연료 표면의 산화막 증가를 억제할 수 있는 수질 조건을 도출하고 그에따른 운전을 통해 원전 작업자의 방사선 피폭량 저감 및 방사성폐기물의 발생을 줄일 수 있을 것으로 여겨진다.

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