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Prediction Equations of Pulmonary Function Parameters Derived from the Forced Expiratory Spirogram for Healthy Adults over 50 years old in rural area (농촌지역 50세 이상 인구의 노력성호기곡선을 이용한 폐활량측정법 검사지표의 추정정상치)

  • Kim, Won-Young;Kim, Kwang-Hyun;Youn, Boung-Han;Lee, Seung-Uk;Cho, Chul-Hyun;Choi, Jin-Su;Kim, Hun-Nam
    • Tuberculosis and Respiratory Diseases
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    • v.45 no.3
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    • pp.536-545
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    • 1998
  • Background: The studies on prediction equations of pulmonary function parameters for adults in Korea have been performed in a reference population mainly consisted of young and middle ages. So they included a relatively few elderly who conducted pulmonary function test frequently in clinic. We established prediction equations of pulmonary function parameters for healthy adults over 50 years old in rural area and compared this results with those of other studies. Therefore we attempted to consider normative values of pulmonary function tests for elderly in Korea. Method: Five hundred thirty-three women and men over 50 years old in rural area were participated. A "healthy" subgroup of 110 women and 32 men were identified by excluding those who had conditions that negatively influenced pulmonary function. We derived prediction equations for FVC, $FEV_1$ and $FEV_1%$ by multiple linear regression method from their age, heights and weights in each sex. Results: Prediction equations for FVC and $FEV_1$ in each sex were derived as follows Male; FVC (L)=0.02488Height(cm)-0.0269Age(years)+0.493 $FEV_1(L)$=0.01874Weight(kg)-0.0282Age(years)+2.906 Female; FVC(L)=0.02160Height(cm)-0.0192Age(years)-0.0125 $FEV_1(L)$=0.01720Height(cm)-0.0194Age(years)+0.3890 Prediction equations for $FEV_1%$ were not derived because $FEV_1%$ didn't have statistically significant terms. Comparing Predicted values that were calculated by substitution into the equations of various studies of mean values of age, heights and weights from this study, FVC and $FEV_1$ values in men of this study were lower than those of other studies. In women, FVC and $FEV_1$ values of this study were as similar as or lower than those of the study conducted for healthy elderly blacks in U.S.A respectively. Conclusion: We have got prediction equations of pulmonary function parameters which were driven from forced expiratory spirogram in adults over 50 years old in rural area. Predicted values of this study were lower than those of other studies which were conducted in Korea. So we consider that the study for spirometry reference values for elderly Korean using the method compatible with ATS recommendation need to be conducted more frequently forward.

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The Utilization of Mutton Fat, Tallow, and Lecithin in the Broilers (육계에서의 양지, 우지 및 레시친의 이용)

  • 고태송;오세정;김춘수
    • Korean Journal of Poultry Science
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    • v.6 no.2
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    • pp.83-90
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    • 1979
  • In order to evaluate the effect of lipids on the utilization of the energy and Protein of the diet, the isocaloric and isoprotein diets added with mutton fat, tallow, and lecithin at the levels of two percent and five percent were prepared. The growth of chicken and the feed efficiency were observed on hatched chicken which were fed a commercial diet for the first week, with starters for the next four weeks, and with finisher diets for the last three weeks respectively during the eight weeks of the experiment. Growth rate, feed efficiency, and average body weight gain per day were similar among the chicken fed diets containing various lipids or at the levels of two percent and five percent. The metabolizable energy of the diets was found to be from 2.713kcal to 3.059kcal per gram, and the metabolizability of the gross energy was from 62 percent to 70 percent. Also the metabolizability of basal diet was higher as compared with the diets containing lipids. And the lower energy utilization was found in the broilers fed diets containing five percent lipids than those of two percent, showing not significant difference between them. Daily metabolizable energy of three week old birds ranged from 132kca1 to 168kcal which resulted in also a tendency of lower values in the five percent diets. And daily retained nitrogen of birds ranged from 0.631 gr to 0.738 gr, which showed an increasing tendency on the birds fed five percent mutton fat and tallow in comparison with those of two percent. But the lecithin brought about a reverse tendency. The digestibility of crude fats was found to be from 48 percent to 76 percent, but not significant difference among diets plus lipids or at the levels of two percent and five percent. The birds fed five percent mutton fat and tallow showed a tendency of lower digestibility as. compared with those fed two percent, but the similar results were found between two percent and five percent lecithin fed to the birds. Then, it was tentatively concluded that the effect of the mutton fat on the energy and protein utilization was similar to tallow but resulted different tendency with lecithin.

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An experimental study on prednisolone-induced interstitial pneumonia caused by Pneumocystis carinii (프레드니솔론 투여에 의한 조폐포자충(Pneumocystis carinii)성 간질성 폐염에 대한 실험적 연구)

  • 신대환;이영하;나영은
    • Parasites, Hosts and Diseases
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    • v.27 no.2
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    • pp.101-108
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    • 1989
  • This study was performed to observe the role of Pneumocystis carinii as an etiologic agent of interstitial pneumonia in immunocompromised hosts. Total 90 male Sprague-Dawley rats, approxi. mately 150-180 g, were used. Fifteen of them were used as control group and remaining 75 (5 groups) were as immunosuppression groups; group 1 received prednisolone (25 mg/kg twice weekly) only; group 2 Prednisolone and tetracycline (75 mk/kg/day) ; group 3 Prednisolone, tetracycline and trimethoprim-sulfamethoxasole (50~250 mg/kg/day) : group 4 prednisolone and trimethoprim-sulfamethoxasole; and group 5 prednisolone and griseofulvin (300 mg/kg/day) until death. The survival days of each group rat were calculated, and upon death their lungs were removed immediately and then stamp smears were prepared and stained by Giemsa or toluidine blue O. For histopathologic observation, lungs were fixed in 10% formalin, cut into sections and stained with Gomori's methenamine silvei, hematoxylin-rosin, and Brovkn & Brenn stain. The results obtained were as follows: 1. The mean survival time of each group rat was 19.3$\pm$5.2 days (group 1), 41.1$\pm$14.0 days (group 2), 50.5$\pm$18.4 days (group 3), 43.0$\pm$22.9 days (group 4) or 21.8$\pm$5.1 days (group 5). Significant differences were noted between group 1 and group 2(p<0.01), group 1 and group 3 (p<0.01), and group 1 and group 4 (p<0.01), which represented bacterial infections were most fatal in immunocompromised rats. Group 5 revealed no difference in the survival day from group 1, while significant differences were noted between group 2 and group 5(P<0.01), group 3 and group 5(p<0.01), and group 4 and group 5(p<0, 01), which represented little importance of fungal infection as the cause of death of the rats. 2. The first fatality due to p. carinii pneumonia occurred 17 days after the beginning of the immunosuppression. The occurrence rate of P. carinii pneumonia in the decreasing order was 92.9% (group 3), 80.0% (group 2 and group 5), 78.6% (group 4) and 33.3% (group 1). With regard to the pathological stage of P. carinii pneumonia, the stage 1 was 11.3%, the stage 2, 28.3%, and the stage 3, 60.4%. 3. Viewing from the duration of immunosuppression, bacterial pneumonia chieay appeared in 1 month, mixed infections (P. carinii and bacteria, or p. carinii and fungi) in 1~2 months, and pure P. carinii pneumonia after 2 months. The present study revealed that P. carinii pneumonia was the most important cause of death of immunocompromised rats later than 1 month after the start of immunosuppression.

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Study on the Screening of the $SO_2$ Resistant Species for Landscape in Air Polluted Area (대기오염지역(大氣汚染地域) 조경용(造景用) 수종(樹種)의 개발(開發)을 위(爲)한 $SO_2$에 대한 내연성(耐煙性) 비교(比較) 연구(硏究))

  • Lim, Soo-Kil;Lee, Joong-Bae
    • Korean Journal of Environmental Agriculture
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    • v.12 no.2
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    • pp.153-161
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    • 1993
  • This study was conducted to compare the resistance and sensitivity of trees with 6 native species exposing to 4 different levels of $SO_2$gas(0.4, 0.7, 1.5 and 3.0 ppm) respectively. The results are summarized as follows : 1. Visible injuries appeared as spots in the region of intervein on the leaves for all the species and the color of the spots changed from light green and/or brown to light brown, dark brown, and/or redish brown. 2. The sensitivity of the species to $SO_2$ was high in the descending order of Zizyphus jujuba, Cataegus pinnatifida, Viburnum sargentii, Weigela subsessilis, Euonymus japonica, and Acer ginnala. 3. The resistance of the species to $SO_2$ was high in the descending order of Acer ginnala, Eunymus japonica Viburnum sargentii, Weigela subsessilis, Zizyphus jujuba, and Crataegus pinnatifida. 4. When the trees were exposed to $SO_2$gas, the contents of chlorophyll a, b, and a+b were consostently lower than those of control, and water soluble sulfur contents in the leaves were higher than those of control. 5. There was no significant correlation between stomatal resistance and the sensitivity(or resistance) of the trees exposed to $SO_2$ gas. 6. In this study, it was concluded that Acer ginnala was more suitable species than the others for landscape in air polluted area because it showed high resistance, low sensitivity, and low stromal resistance to $SO_2$gas exposure.

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The study of the symbolic meaning of colors used in the animation "Uproar in the Heaven" - Focused on the traditional Chinese five color concept (애니메이션 <대요천궁>에 사용된 색상의 상징적 의미에 관한 연구 : 중국 전통 오색관을 중심으로)

  • Geng, Ling;Lee, Jong-han
    • Cartoon and Animation Studies
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    • s.51
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    • pp.129-158
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    • 2018
  • China has had many excellent Chinese-style animation since the 1950s. These animations are of distinctive Chinese national characteristics. They have won many awards both at home and abroad, such as "Feelings of Mountains and Waters", "Uproar In Heaven", "Why is the Crow Black-Coated" and so on. But nowadays, Chinese animations that mimics Japanese and American animation are very often, and there are few animation works with rich traditional Chinese culture. There are some works in the name of Chinese style, but they have not been fully accepted by the audiences. If one wants to create animated works of Chinese style, the author must have an in-depth understanding of Chinese traditional and folk art. Animation can not be designed only on the surface. This paper mainly studies the traditional five color concept in China and its application in animation. The purpose is to provide some references to differentiate Chinese animation from other countries in terms of style and color. The main content of this paper is to understand the concept and history of Chinese traditional five color views, and to know that this color system has reflected the ancestors' concept of nature and society. On the basis of five monochromatic colors, red, yellow, green, white and black, it is a kind of complex color concept that has been developed and perfected continuously after a long period of accumulation and precipitation in the practice of life. It is the theoretical basis of Chinese traditional color system and a complete set of historical, cultural, philosophical and religious theories. Finally, this paper analyzes the colors and their symbolic meanings of the main roles in "Uproar In Heaven", a color long animation produced by Shanghai Animation Film Studio, including Sun Wukong, the Jade Emperor and Na Zha. Color is the first visual language. The use of color symbols to express the inner feelings, status, good and evil of the characters will affect the audience's emotions, behaviors and opinions imperceptibly. The traditional Chinese five color concept has gone through such a long history, and its symbolic meaning has a more profound impact on Chinese people. Applying the color concept and symbolic meaning of Chinese traditional five color concept will further highlight the personalities and emotions of the roles in Chinese style animations. This paper takes the five-color view as the theoretical basis, and through the analysis of cartoons with traditional Chinese color, the author finds ways to flexibly use traditional Chinese culture.

Influence of Panax Ginseng on Hepatic DNA Synthesis in Mice (고려인삼이 마우스의 간조직 DNA 합성능에 미치는 영향( I ))

  • Chae, Y.B.;Chang, W.S.;Kwon, Y.C.
    • The Korean Journal of Physiology
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    • v.8 no.1
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    • pp.27-30
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    • 1974
  • It was planned to evaluate the influence of Panax Ginseng upon hepatic DNA synthesis in mice by observing incorporation of $[^3H]$ thymidine into the tissue cells. Thirty male mice$(body\;weight:\;18{\sim}20\;g)$ were divided equally into the ginseng and the saline groups. Each animal of the ginseng and the saline groups received every day (subcutaneously) 0.05 m1/10 g body weight of ginseng extract (4mg of ginseng alcohol extract in 1 ml of saline) and the same amount of saline, respectively, for 5 days. On the 5th experimental day, all animals received $1\;{\mu}Ci/g$ body weight of $[^3H]$ thymidine intraperitoneally 2 hours after the last medication. Five animals, at a lime, of each group were sacrificed 1, 10, and 24 hours after thymidine administration, and their hepatic radioactivity was measured autoradiographically in terms of the % number of radioactive cells in 1,000 cell counts (Radioactive Index, R.I.). Following results were obtained: 1. The hepatic radioactive indices obtained from the saline group 1, 10, and 24 hour after $[^3H]$ thymidine administration were $3.23{\pm}0.23,\;5.20{\pm}0.21,\;and\;6.00{\pm}0.30\;(mean{\pm}S.D.)$, respectively. 2. The corresponding values obtained from the ginseng group $(4.22{\pm}0.33,\;6.32{\pm}0.32,\;and\;7.42{\pm}0.35)$ were significant higher than the values of the saline group. The inference from the above results was that the ginseng facilitated hepatic DNA synthesis.

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A Study on Contact Dermatitis-Causing Substances Concentration in Commercial Oxidative Hair-Coloring Products (유통 산화형 염모제의 접촉성피부염 유발물질 함량 연구)

  • Na, Young Ran;Koo, Hee Soo;Lee, Seung Ju;Kang, Jung Mi;Jin, Seong Hyeon
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.40 no.2
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    • pp.203-214
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    • 2014
  • We measured the contact dermatitis-causing substances concentrations in 28 commercial oxidative hair-coloring products. This study was aimed to provide the fundamental data about oxidative hair-coloring products. We selected 10 oxidation dyes (p-phenylenediamine, toluene-2,5-diamine, m-phenylenediamine, nitro-p-phenylenediamine, p-aminophenol, m-aminophenol, o-aminophenol, p-methylaminophenol, N,N'-bis(2-hydroxyethyl)-p-phenylenediamine sulfate, 2-methyl-5-hydroxyethylaminophenol) and 4 heavy metal (nikel; Ni, chromium; Cr, cobalt; Co, copper; Cu) as contact dermatitis-causing substances. To identify 10 oxidation dyes, hexane-2% sodium sulfite was used for the rapid and simple extraction and ultra performance liquid chromatography (UPLC) analysis was used for simultaneous analysis in 12 minutes. 10 oxidative dyes were detected as indicated on the product packaging and each concentration was lower than prescribed upper concentration limit by pharmaceutical manufacturing standards. And we analysed inductively coupled plasma-optical emission spectrophotometer (ICP-OES) for content search of heavy metal after microwave digestion. The heavy metal average concentration in oxidative hair-coloring products was 0.572 ${\mu}g/g$ for Ni, 3.161 ${\mu}g/g$ for Cr, 2.029 ${\mu}g/g$ for Co, 0.420 ${\mu}g/g$ for Cu, respectively. The average of concentration in powder type (henna) was higher than those of other foam and cream type oxidative hair-coloring products as follows; 1.800 ${\mu}g/g$ for Ni, 10.127 ${\mu}g/g$ for Cr, 7.082 ${\mu}g/g$ for Co, 1.451 ${\mu}g/g$ for Cu. Hair coloring products were classified into the six colors - black, dark brown, brown, dark brown, light brown, red brown and analyzed. Brown color had the highest average concentration of Co and the others had the highest average concentration of Cr.

Construction of Data System on Seed Morphological Traits and Functional Component in Tartary Buckwheat Germplasms (쓴메밀 유전자원의 종자특성과 유용성분 변이에 관한 자원 정보 구축)

  • Kim, Su Jeong;Sohn, Hwang Bae;Hong, Su Young;Lee, Jong Nam;Kim, Ki Deog;Suh, Jong Taek;Nam, Jeong Hwan;Chang, Dong Chil;Park, Min Woo;Kim, Yul Ho
    • Korean Journal of Plant Resources
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    • v.33 no.5
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    • pp.446-459
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    • 2020
  • This study analyzed the phenotypes and chemotypes of 74 tartary buckwheat (Fagopyrum tataricum) germplasms using principal component analysis and cluster analysis. The average seed size of tartary buckwheat germplasm was 5.2 × 3.4 mm, which is smaller than the seed size of common buckwheat. The dark browned colored ovate or elliptic shape was mostly observed in collected germplasm. The average content of rutin was 1,393 mg per 100 g dry weight (DW) in tartary buckwheat seed. Similarly, the flavonoid and polyphenol contents ranged from 253 to 2,669 and 209 to 1,823 mg, respectively, per 100 g DW in the collected germplasm. The three components (PC1, 2, and 3) of principal component analysis revealed 68.55% of the total variance of the collected accessions. Cluster analysis using descriptors showed that 74 accessions were clustered into five groups. The study showed that the most interesting resources for functional breeding programs are: Five resources (HLB1004, HLB1005, HLB1007, HLB1009, and HLB1013) due to the rich rutin, polyphenol, and flavonoid.

The Influence of over Foraging, and Pollinating Activities on Tomato Fruits by a Korean Native Bumblebee, Bombus ignitus S, (Hymenoptera : Apidae) in Cherry-tomato Houses (시설방울토마토에서 호박벌(Bombus ignitus)의 방화활동 및 과도한 방화가 토마토에 미치는 영향)

  • Lee, Sang-Bum;Bae, Tae-Woong;Kim, Sam-Eun;Yoon, Hyung-Ju;Lee, Myung-Ryul;Chae, Young
    • Korean journal of applied entomology
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    • v.42 no.4
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    • pp.293-300
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    • 2003
  • This study examined the foraging activities and the Influence of excessive foraging activity by B. ignitus workers on the quality of cherry-tomato fruits in cherry-tomato green-house. The peak time of pollination by B. ignitus worker was recorded at 8:00 and the average of foraging time on each flower was 11.7 secs. The total pollinating time of B. ignitus was 41 mins and 37 secs and its total number of visiting flowers was 195.2. The average time of staying on flowers was 8.8 ${\pm}$5.4 secs when two bumblebees were allowed to pollinate per Pyong (3.954 square yards) in the green house of tomatoes for 24 hours, but it was two times shorter (4.0${\pm}$3.1 secs) compared with that when one bumble-bee was allowed to pollinate per Pyong for one hour. The stamen color of tomato flowers visited by the bumblebee for one hour was brown while the stamen color for 24 hours was dark brown due to the frequent visiting. The average fruit bearing rate of the 4th-6th clusters of tomatoes visited for one hour was 48.9%, which was not significantly different from those allowed to visite for 24 hours. However, the number of seeds of flowers visited for 24 hours was 64.0, which was more than 55.3 seeds of flowers visited for one hour. The weight of fruit was 25.4 g and 24.4 g, respectively. The sweetness was not different significantly between one and 24 hours of visit (P > 0.05). The result revealed that end pro-duct of cherry-tomato was not influenced by over foraging activity of B. ignitus workers on tomato flowers.

The Role of Bronchoscopy for the Staging in Patient with Peripheral Lung Cancer (말초형 폐암 환자에 있어서 병기판정을 위한 기관지 내시경검사의 필요성)

  • Baek, Seung-Min;Sea, Hyang-Eun;Kim, Se-Hwan;Kim, Seong-Kyu;Kim, Yean-Jae;Lee, Byung-Ki;Kim, Won-Ho;Park, Jae-Yang;Jung, Tae-Hoon
    • Tuberculosis and Respiratory Diseases
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    • v.51 no.2
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    • pp.147-154
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    • 2001
  • Background : Bronchoscopy has been widely used for a histologic diagnosis through a transbronchial lung biopsy or for staging of patients with peripheral lung cancer. However a transthoracic needle aspiration (TTNA) has been used more widely for a histologic diagnosis in patient with a small size nodule or a nodule located in the outer portion of the lung because of the low diagnostic yield of bronchoscopy in these cases. The role of bronchoscopy for staging is not well established in patients with peripheral lung cancer diagnosed by a TTNA or patients who are undergoing surgery without a histologic diagnosis. Method: To evaluate the role of bronchoscopy for the staging in patients with peripheral lung cancer, who were diagnosed by TTNA, the medical records of 86 patients with peripheral lung cancer who underwent bronchoscopyat Kyungpook National University Hospital between January 1995 and May 1997 were reviewed. Results : While 53 cases had normal bronchoscopic findings, 33 cases had abnormal bronchoscopic findings comprising 9 cases of tumor, 10 cases of infiltration and 14 cases of compression of which there were 25 cases of T1 and 8 T2 endoscopically. The bronchoscopic staging did not influence the changes of the clinical stage of lung cancer. The frequencies of bronchial involvement tended to increase as the sizes of the nodule increased. Among the 42 patients who underwent surgery, 9 patients staged higher after operation because of lymph node involvement in 8 patients and the involvement of the pulmonary artery in 1 patient. No case staged above after operation due to a bronchial invasion. Conclusion : These findings suggests that bronchoscopy is not useful for staging in patients with peripheral lung cancer diagnosed by a TTNA.

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