• Journal of Food Hygiene and Safety
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• v.31 no.1
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• pp.59-66
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• 2016

It has been generally accepted that obesity and overweight are associated with metabolic diseases and cancer incidence. In fact, obesity increased risks of cancers i.e. breast, liver, pancreatic and prostate. Celastrol is a pentacyclic triterpenoid isolated from Thunder god vine, was used as a Chinese traditional medicine for treatment of inflammatory disorders such as arthritis, lupus erythematosus and Alzheimer's disease. Also, celastrol has various biological properties of chemo-preventive, neuro-protective, and anti-oxidant effects. Recent studies demonstrated that celastrol has anti-proliferation effects in different type of obesity-related cancers and suppresses tumor progression and metastasis. Anticancer effects of celastrol include regulation of $NF-{\kappa}B$, heat shock protein, JNK, VEGF, CXCR4, Akt/mTOR, MMP-9 and so on. For these reasons, celastrol has shown to be a promising anti-tumor agent. In this review, we will address the anticancer activities and multiple mechanisms of celastrol in obesity-related cancers.

• Korean Journal of Food Science and Technology
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• v.19 no.2
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• pp.81-88
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• 1987

Rheological properties of rehydrated suspensions of two kinds of freeze dried Kochujang powders, processed at different freezing rates, were compared with raw Kochujang using Brookfield wide-gap rotational viscometer at $25^{\circ}C-60^{\circ}C$. Shear rates ranged from $0.1965\;sec^{-1}$ to $1.9650\;sec^{-1}$ and solid content ranged from 47% to 56%. Rehydrated suspensions of quickly frozen Kochujang powder and slowly frozen Kochujang powder, and raw Kochujang exhibited pseudoplastic behaviors with yield stress and presented thixotropic properties which followed the second-order kinetic behavior proposed by Tiu. Suspensions of Kochujang powders exhibited considerably higher decaying rates than raw Kochujang. The dependency of the equilibrium structure parameter on the shear rate was weak, and there were no significant differences among the values of structure parameters of three samples. The temperature dependency of the apparent viscosity of Kochujang suspension was fully expressed by Arrhenius equation and activation energies of suspensions of quickly frozen Kochujang powder and slowly frozen Kochujang powder, and raw Kochujang were 2.21, 2.18, and 2.32 Kcal/g.mole respectively. Consistency indices of three samples increased with solid content and decreased with temperature. Flow behavior indices of three samples showed no considerable dependency on the temperature and solid content. There were no significant differences in the rheological properties between two Kochujang powders.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.29 no.6
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• pp.569-576
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• 2011

Recently the establishment of high accuracy 3D spatial information has been largely stimulated according to the increase in need of such 3D spatial information. In the fields of constructions and civil works, studies on increasing the productivity in these fields through converging them with other fields using the established 3D spatial information have been conducted. In such a tendency, BIM (Building Information Modeling) technologies have been rapidly applied to the fields of constructions and civil works. In particular, in the fields of constructions and civil works that represent a life span of plan-design-construction-maintenance, some BIM application methods and plans for the characteristics in each step have been proposed. Thus, the objective of this study is to simulate a project that is reasonable and can be optimized in connection with 3D spatial information and BIM technologies escaped from the conventional civil construction process that is based on empirical, statistical DB, and 2D information. For achieving this objective, 3D terrain data for the subject area engaged in this study using aerial photographs and airborne LiDAR was established. Also, a counter plan for the issues, which cannot be solved in the conventional methods for managing civil work projects, is applied through implementing bridge-based civil structure BIM by combining them with objective information.

• Journal of Korean Society of Transportation
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• v.36 no.2
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• pp.86-97
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• 2018

City tour service has a function not only informs tourists of historical and cultural resources in the city but also contributes to improving city image making. In this study, a questionnaire was surveyed to tourists who used Suwon city tour to find out which factors make affect their intention to re-visit or recommendation to others. Structural equation model was constructed and set a hypothesis that overall city tour satisfaction would have a positive effect. The fitness of the final model was found out to be meet the statistical criteria. As a result of the final model, both satisfaction of guide and satisfaction of city tour operation were significant at 5% significance level (P<0.01). On the other hand, both satisfaction of bus facility and of promotion, customer service were statistically insignificant. Consequently, City tour service satisfaction was found to effect to the intention of re-visit and recommendation. Especially, The higher the satisfaction of guide and city tour operation, the more tendency to recommend. It is expected that local government which operates city tour bus could take advantage of this result in the future.

• Applied Chemistry for Engineering
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• v.2 no.2
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• pp.108-118
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• 1991

Interactions between pyridine hydrodenitrogenation (HDN) and m-cresol hydrodeoxygenation(HDO), and the kinetic analysis were studied over sulfided $CoMo/{\gamma}-Al_2O_3$ catalyst at the range of temperatures between 473 K and 723 K, the total pressures between $10{\times}10^5Pa$ and $50{\times}10^5Pa$, and the contact times between 0.0125 g-cat. hr/ml-feed and 0.03g-cat. hr/ml-feed. HDN of pyridine and HDO of m-cresol were inhibited by each other and the inhibition effect of HDO by pyridine is higher than that of HDN by m-cresol. But reactivity of m-cresol is higher than that of pyridine. The rate equations of pyridine and m-cresol were given to be ${\gamma}_{HDN}=k_{HDN}{\cdot}K_pC_p/(1+K_cC_c+K_pC_p)$ and ${\gamma}_{HDO}=k_{HDO}{\cdot}K_cC_c/(1+K_cC_c+K_pC_p)$ in terms of Langmuir-Hinshellwood-Hougen-Watson model. At each temperature, reaction rate constants and adsorption equilibrium constants were determined and activation energies of pyridine HDN and m-cresol HDO are 13.83kcal/mol, respectively and the heat of adsorption are -6.458 and -5.045kcal/mol, respectively.

• Applied Chemistry for Engineering
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• v.18 no.5
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• pp.415-423
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• 2007

Pyrolysis characteristics of sawdust and rice husk as biomass resources in a thermogravimetric analysis were determined. Experiments were carried out with a linear heating rate under inert atmosphere of $N_2$ gas. Pyrolysis of the biomass can be classified as a lower temperature reaction zone where the major component of holocellulose is thermally decomposed and a high temperature reaction zone where lignin is thermally decomposed. The obtained data was analyzed by the two-step consecutive reaction model. Activation energies of sawdust and rice husk are found to be respectively 82.5 kJ/mol and 85.1kJ/mol in the low temperature zone according to the first order reaction model and 19.7 kJ/mol, 22.0 kJ/mol in the high temperature zone according to the three-way transport model. The reaction rate constant with variation of heating rate can be well predicted by the kinetic compensation relation of Gaur-Reed.

• Proceedings of the KAIS Fall Conference
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• 2009.05a
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• pp.339-342
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• 2009

본 연구는 대한민국건강도시협의회 회원도시 23개 자치단체 건강도시 추진 담당자에게 건강도시 추진현황 및 발전방향을 모색하기 위해 2007년 2월부터 2007년 12월 까지 대한민국건강도시협의회 회원 도시 담당자들에게 구조화된 설문지를 통해 건강도시 사업 일반현황, 건강도시 사업 기본현황, 건강도시 발전방향 등에 대하여 조사 분석 하였으며 모든 처리 방법은 SPSS 12.0 version 통계프로그램을 이용하였다. 본 연구의 결과는 다음과 같다. 1. 연구대상자의 지자체 일반현황은 23개자치단체중 도시형(47.8%), 농촌형(52.2%)이며, 가입년도별로는2004년(17.4%), 2005년(30.4%), 2006년(26.1%), 2007년(26.1%)로 나타났다. 2. 건강도시 사업추진현황을 보면, 장기계획수립(43.4%), 생활터접근(69.5%), 민정보제공(78.2%), 협력대학(82.6%), 부서협력잘됨(34.7%), 네트워크적극참여(34.7%), 세미나실시(47.8%)로 나타났다. 3. 건강도시 발전방향 으로는 추진 시 가장 어려운 점은 사업개발(39.0%), 우선순위로는 부서협력(30.4%), 핵심인물단체장(82.6%), 발전가능성지속발전(65.2%), 발전기여(86.9%), 시행주체국가주도(52.1%)로 나타났다. 4. 도시형태별 건강친화성 평가점수는 69점이하 도시형(8.60%), 70~79점농촌형(21.7%), 80~89점 도시형(26.0%), 농촌형(17.3%), 90정이상 도시형(13.0%), 농촌형(13.0%)로 나타났다. 5. 조직구성여부별 건강도시 기본현황 추진실태를 살펴보면, 조례제정여부 조직구성(100%), 미 구성(81.8%), 운영위원회 구성 조직구성(100%), 미 구성(54.5%), 프로파일작성 조직구성(100%), 미 구성(81.8%), 예산확보 조직구성(100%), 미 구성(81.8%)로 나타났다. 조직구성이 건강도시 사업추진에 많은 영향을 미치는 것으로 분석된다. 향후 건강도시 사업추진 시에는 건강도시를 추진하는 담당부서 구성이 가장 중요한 것으로 판단되며, 건강도시 사업추진은 먼저 시작한 도시가 건강친화성 평가 점수에서 높게 나타났다. 이에 따라 건강도시 사업은 일시적인 사업이 아닌 끊임없이 노력하는 도시가 되어야 하며, 건강도시 사업의 활성화를 위해서는 국가주도하에 실시하는 것이 절실히 필요 한 것으로 판단된다.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.10
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• pp.5260-5267
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• 2013

In order to create a successful regional development model, there should be an effort to foster a strategic industry which boosts a geographical features of rural areas. Because, It must be clear that the strategic industry chosen between choice and concentration of the development of the local industry development which boosts the local economy revitalization. The local government should have continual concern and roles to fulfil political subjects and keep estimating about the possibility that there could be the sustainable development by Task Ahead of the local industry. This study's indicators were established for the adequacy evaluation of the industrial policy by focusing on domestic regional development's success example. Next, Conjoint analysis was conducted on the Experts. On the basis of this analysis, the weights of indicators are derived. And this study suggest the reasonable evaluation system to take Sustainable industry plan of regional strategic. Consequently, 'Regional development' sector separate 3 categories which are 'Local economy', 'Human Resource Development', 'local marketing' and 9 indicators were derived. 'Industrial development' sector derived 9 indicators about 'Construction of infrastructure', 'Technical development' and 'business support'. Looking through the implications of this study. First, the problem needed to be supplemented based on the Diversity and concreteness of Evaluation system when government assesses regional industry development policy. Second, local government have to strategically consider the possibility of convergence between industries and easiness of network in a broad region. Finally, Foundation and support of the professional manpower and companies for the regional industries must be established.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.42 no.4
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• pp.768-779
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• 2017

Recently, the great number of mobile devices causes excessive data/control traffic problems in the centralized LTE/EPC network and such dramatically increased traffic is emerging as a critical issue. In the Centralized Mobility Management (CMM) based LTE/EPC network, the Packet Data Network Gateway (P-GW) plays the centralized mobility anchor role and it accommodates most of data traffic. To solve this problem, the IETF has proposed the Distributed Mobility Management (DMM) scheme, but it has only focused on the data traffic load balancing and could not solve the control traffic overload problem. In this paper, therefore, we propose a new SDN based hybrid CMM/DMM Mobility Management (C-DMM) architecture based on Packet Network Edge Gateway (P-EGW), and introduce a selection scheme between CMM and DMM according to a device's mobility and the number of PDN connections. In order to prove the efficiency of the proposed architecture and scheme, we compare the data traffic processing load and the control traffic processing load over each scheme by emulating them in the ONOS controller and the Mininet environment.

• Journal of the Economic Geographical Society of Korea
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• v.17 no.4
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• pp.771-785
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• 2014

As marine desertification and chlorosis in Korean coast have been intensified over time, Korean government is promoting marine afforestation projects. However, marine afforestation location is mainly decided by administrative convenience. Also, there is limited literature on location suitability about the marine afforestation. This study aims to assess location suitability of marine afforestation considering 3 significant criteria: ecological, submarine topographical, and human-social environment. Jeju, the study area of this study, first observed chlorosis in Korean coast at the small fishery town in Seogwipo. Jeju is currently suffering from chlorosis all around the island. Habitat Evaluation Procedure (HEP), 3D kriging, Analytic Hierarchy Process (AHP) is applied as analysis methods. Especially, 3D kriging is utilized for modeling 3D ocean space reflecting ocean environment appropriately. The result shows that Jocheon coast has better location suitability than Seogwipo Pyoseon coast. Jocheon coast has the maximum 61% suitability as the habitat of Ecklonia cava Kjellman, and is highly evaluated in other criteria. The results of this study are expected to find optimal marine afforestation location, and to contribute to the restoration of the Jeju coastal ecosystem and the revitalization of Jeju fishing village societies.