• Title/Summary/Keyword: 환경동태성

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Toxicokinetics of 4-tert-octylphenol in rats (Rat에서의 Octylphenol의 독성동태 연구)

  • 손수정;강현구;이선우;서수경;박인숙;안미령;최홍석;조재민;손동환
    • Environmental Mutagens and Carcinogens
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    • v.21 no.2
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    • pp.122-127
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    • 2001
  • 4-tert-octylphenol (OP) is a surfactant additive widely used in the manufacture of a variety of detergents and plastic products. Also, OP is known to have estrogenic activity by interacting with development and functions of endocrine system. This study was carried out to obtain toxicokinetic parameters of OP in male Sprague-Dawley rats. Male rats were administered OP, by either single oral (gavage) applications of 50, 100 or 200 mg/kg body weight. or a single intravenous injections of 1, 5 or 10 mg/kg body weight. Blood samples taken at several time intervals after administration were obtained from the femoral artery. Analysis of blood samples for OP was performed by gas chromatography mass spectrometry (GC/MS). The detection limit of OP was 1.9 ng/$m\ell$ at SIM (selected ion monitoring) mode of GC/MS. Calibration curve for analysis of the concentrations of OP in plasma was (OP/butylphenol peak area ratio) = 0.0294 $\times$ (plasma cone.) + 0.028 ($r^2$= 0.9991). The OP plasma concentration was 3921 ng/$m\ell$ immediately after single intravenous application, decreased rapidly within 45 min, and was detectable at low concentration up to 6 hr after application. When administered orally in rats (50, 100 and 200 mg/kg), OP was detected in the blood early after gavage administration, indicating the rapid initial uptake from gastrointestinal tract, with Tmax obtained from 0.67~0.83 hr. Using the AUC (area under the curve) of plasma concentration vs. time, low oral bioavailabilities of 1.2, 5.0 and 5.3% were calculated for the 50, 100 and 200 mg/kg groups, respectively.

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The Causes of Conflict and the Effect of Control Mechanisms on Conflict Resolution between Manufacturer and Supplier (제조-공급자간 갈등 원인과 거래조정 방식의 갈등관리 효과)

  • Rhee, Jin Hwa
    • Journal of Distribution Research
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    • v.17 no.4
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    • pp.55-80
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    • 2012
  • I. Introduction Developing the relationships between companies is very important issue to ensure a competitive advantage in today's business environment (Bleeke & Ernst 1991; Mohr & Spekman 1994; Powell 1990). Partnerships between companies are based on having same goals, pursuing mutual understanding, and having a professional level of interdependence. By having such a partnerships and cooperative efforts between companies, they will achieve efficiency and effectiveness of their business (Mohr and Spekman, 1994). However, it is difficult to expect these ideal results only in the B2B corporate transaction. According to agency theory which is the well-accepted theory in various fields of business strategy, organization, and marketing, the two independent companies have fundamentally different corporate purposes. Also there is a higher chance of developing opportunism and conflict due to natures of human(organization), such as self-interest, bounded rationality, risk aversion, and environment factor as imbalance of information (Eisenhardt 1989). That is, especially partnerships between principal(or buyer) and agent(or supplier) of companies within supply chain, the business contract itself will not provide competitive advantage. But managing partnership between companies is the key to success. Therefore, managing partnership between manufacturer and supplier, and finding causes of conflict are essential to improve B2B performance. In conclusion, based on prior researches and Agency theory, this study will clarify how business hazards cause conflicts on supply chain and then identify how developed conflicts have been managed by two control mechanisms. II. Research model III. Method In order to validate our research model, this study gathered questionnaires from small and medium sized enterprises(SMEs). In Korea, SMEs mean the firms whose employee is under 300 and capital is under 8 billion won(about 7.2 million dollar). We asked the manufacturer's perception about the relationship with the biggest supplier, and our key informants are denied to a person responsible for buying(ex)CEO, executives, managers of purchasing department, and so on). In detail, we contact by telephone to our initial sample(about 1,200 firms) and introduce our research motivation and send our questionnaires by e-mail, mail, and direct survey. Finally we received 361 data and eliminate 32 inappropriate questionnaires. We use 329 manufactures' data on analysis. The purpose of this study is to identify the anticipant role of business hazard (environmental dynamism, asset specificity) and investigate the moderating effect of control mechanism(formal control, social control) on conflict-performance relationship. To find out moderating effect of control methods, we need to compare the regression weight between low versus. high group(about level of exercised control methods). Therefore we choose the structural equation modeling method that is proper to do multi-group analysis. The data analysis is performed by AMOS 17.0 software, and model fits are good statically (CMIN/DF=1.982, p<.000, CFI=.936, IFI=.937, RMSEA=.056). IV. Result V. Discussion Results show that the higher environmental dynamism and asset specificity(on particular supplier) buyer(manufacturer) has, the more B2B conflict exists. And this conflict affect relationship quality and financial outcomes negatively. In addition, social control and formal control could weaken the negative effect of conflict on relationship quality significantly. However, unlikely to assure conflict resolution effect of control mechanisms on relationship quality, financial outcomes are changed by neither social control nor formal control. We could explain this results with the characteristics of our sample, SMEs(Small and Medium sized Enterprises). Financial outcomes of these SMEs(manufacturer or principal) are affected by their customer(usually major company) more easily than their supplier(or agent). And, in recent few years, most of companies have suffered from financial problems because of global economic recession. It means that it is hard to evaluate the contribution of supplier(agent). Therefore we also support the suggestion of Gladstein(1984), Poppo & Zenger(2002) that relational performance variable can capture the focal outcomes of relationship(exchange) better than financial performance variable. This study has some implications that it tests the sources of conflict and investigates the effect of resolution methods of B2B conflict empirically. And, especially, it finds out the significant moderating effect of formal control which past B2B management studies have ignored in Korea.

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A Comparative Study on Research Capabilities of Engineering Fields (대학알리미 공시정보를 이용한 공학분야 연구역량 비교)

  • Om, Kiyong;Kim, Dongtae;Lee, Jaewon
    • The Journal of Korean Institute for Practical Engineering Education
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    • v.4 no.2
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    • pp.150-157
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    • 2012
  • This study examined the differences in research capability among engineering fields using the data of research support organizations involving National Research Foundation of Korea(NRF), SCI Korean Council for University Education (KCUE) and so on. The findings of the study confirm that there are statistically significant differences in research capability among selected engineering fields, and provide implications for university administrators and academic policy-makers to adopt discriminative evaluation tools for performance evaluation of university faculties in consideration of their engineering fields.

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Agenda-setting Process in Enacting the Korea's Nuclear Safety Act in 2011 adopting Multi Streams Approach (다중흐름모형을 통한 원자력 규제정책 의제설정 과정 분석: 2011년 원자력안전법 제정을 중심으로)

  • Kim, Yeong-Jun;Lee, Chan-Gu
    • Proceedings of the Korea Technology Innovation Society Conference
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    • 2017.11a
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    • pp.49-79
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    • 2017
  • 본 연구는 2011년 "원자력안전법" 제정 사례에 있어 정책의제 설정 과정을 동태적으로 이해하기 위해 다중흐름모형을 활용하여 분석을 수행하였다. 연구범위는 이명박 정부와 제18대 국회임기가 겹치는 기간인 2009년부터 2011년 간 기간으로서, 동 기간은 UAE 원전수출과 후쿠시마 원전사고라는 정 반대의 초점사건이 발생하면서 두 차례 의제설정 여부를 결정하는 정책의 창이 개방되었다. 분석결과, 문제의 흐름 영역에서는 정부의 원자력 정책에 있어 진흥과 규제기능을 별도 법령으로 분리하고 독립된 예산 및 전담조직을 구성하는 체계를 구축해야 한다는 문제는 장기간 존재해왔다. 1990년대부터 소수의 법학자들을 중심으로 문제인식과 대안제시가 이뤄지는 정책의 흐름이 발전되어 왔는데, 이후 UAE 원전수출 이후 2010년에 이르러서야 본격적으로 표출집단인 관료와 국회의원을 통해 구체적 대안이 제시되었고, 2011년 후쿠시마 원전사고 직후인 5월 원자력안전법이 제정되었다. 분석결과, 2009년 UAE원전수출 이후, 수출 확대 목적으로 제시된 원자력 규제 독립 법안이 통과되지 못했던 것에 반해, 2011년 후쿠시마 이후 원자력안전법이 통과 된 이유는 대안의 가치정합성, 사회여론, 정치환경 등 정치의 흐름이 크게 작용한 것으로 분석되었다.

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Growth and Nutrient Dynamics of Planted Tree Species Following Fertilization in a Fire-Disturbed Urban Forest (도시 숲 산불피해지의 시비에 따른 식재 수목의 생장 및 양분 동태)

  • Choonsig Kim;Gyeongwon Baek
    • Journal of Korean Society of Forest Science
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    • v.113 no.2
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    • pp.143-152
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    • 2024
  • This study was conducted to evaluate the growth and nutrient dynamics in response to fertilization of four tree species (LT: Liriodendron tulipifera L.; PY: Prunus yedoensis Matsumura; QA: Quercus acutissima Ca rruth; a nd PT: Pinus thunbergii Parl.) planted in a fire-disturbed urban forest in Bongdaesan (Mt.), Ulsan Metropolitan Area, South Korea. The trees were planted in 2009, and compound fertilizers (N6P4K1) were applied in April 2013 and March 2014. Tree growth, soil, and foliage nutrients were examined from March 2013 to October 2016. The regression coefficients for the increment of the diameter at breast height (DBH) significantly differed between the fertilized and unfertilized plots, suggesting the significant effects of fertilization. By contrast, fertilization did not affect the coefficients for height increments. Regarding soil nutrient contents, organic carbon and total nitrogen concentrations were lower in the fertilized plots than in the unfertilized plots, whereas available phosphorus, exchangeable calcium, and magnesium concentrations were higher in the fertilized plots than in the unfertilized plots. In foliage, nitrogen and phosphorus concentrations were higher in the fertilized plots than in the unfertilized plots, whereas potassium, calcium, and magnesium concentrations were not affected by fertilization. Nutrient concentration of foliage among the tree species were higher in LT and PY than in QA and PT. These results suggest that fertilizers may be used to enhance soil fertility and the growth and nutrient status of tree species planted in a fire-disturbed urban forest.

Zooplankton Community Dynamic in Lentic Freshwater Ecosystems in the Nakdong River Basin (낙동강 유역권 내 정수생태계의 동물플랑크톤 군집 동태)

  • Kim, Seong-Ki;Hong, Dong-gyun;Kang, MeeA;Lee, Kyung-Lak;Lee, Hak Young;Joo, Gea-Jae;Choi, Jong-Yun
    • Korean Journal of Environment and Ecology
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    • v.29 no.3
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    • pp.410-420
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    • 2015
  • In order to estimate the influence of environmental factors on zooplankton communities in lentic freshwater ecosystems, 20 reservoirs and wetlands were monitored by season in 2013. A total of 109 species of zooplankton were identified during the study period. Zooplankton assemblage showed a different distribution in its density and diversity in accordance with the seasons. In particular, the density of zooplankton (98 species and 603ind. L-1) was the most in autumn when compared to the other seasons. In order to effectively analyze zooplankton distribution that are affected by various environmental factors, a Self-Organizing Map (SOM) was used, which extracts information through competitive and adaptive properties. A total of 11 variables (8 environment factors and 3 groups of zooplankton) were patterned on to the SOM. Based on a U-matrix, four clusters were identified from the model. Among zooplankton communities, rotifer displayed a positive relationship with water temperature, and cladocerans and copepod were positively related to conductivity, chlorophyll a, and nutrient factor (i. e. TN and TP). In contrast, high dissolved oxygen appeared to have a negative effect on zooplankton distribution. Consequently, the SOM results depicted a clear pattern of zooplankton density clusters partitioned by environmental factors, which play a key role in determining the seasonal distribution of zooplankton groups in lentic freshwater ecosystem.

Physico-Chemical Environment and Productivity of the Phytoplankton Community in the Jido Pond Ecosystem (지도지생태계의 물리화학적환경과 식물성 플랭크톤군집의 생산성)

  • Song Seung-Dal;M. Anwarul Huque
    • Journal of environmental and Sanitary engineering
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    • v.5 no.2
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    • pp.117-122
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    • 1990
  • The Jido Pond system was investigated from April, 1979 through March, 1980, in respect of seasonal changes in physico-chemical factors: i.e., temperature, pH, DO, BOD, COD, $Cl^-, \; Mg^{++}$, alkalinity, detergent, $SiO_2, PO_4\;^{3-}, NH_4\;^+, NO_2\;^-, NO_3\;^-$, total N, OM and OC; phytoplankton community growth; and the ecosystem metabolism. The phytoplankton community was represented by 23 species belonging to Chlorophyta, Bacillariophyta and Cyanophyta; each sharing 11, 9 3 respectively. The Chlorophyceans dominated the phytoplankton community contributing 75% of the total ?미 counts. The ranges of biotic diversity indices were, d, 0.85~2.80; H, 1.10~2.40; c, 0.13~0/40; and 3, 0.56~0.90. The chlorophyll standing crop varied in between 0.043 and 0.385g/$\textrm{cm}^2$ surface area. The ranges of photosynthetic and respiratory rates were 0.36~4.50; and 0.10~1.40 $O_2$ mg/1/hr, respectively. The monthly areal net primary production varied from 23.9 to 305.1C g/$\textrm{m}^2$/month. The Eu of the net production seasonally varied in between 0.31 and 7.80%, and the annual mean was 2.44%. The annual turnover times of phosphorus and nitrogen were 20 and 3 days, respectively.

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Is Dynamic Loan Loss Provisioning Necessary in Korea? (동태적 대손충당금제도 도입의 타당성 분석)

  • Kang, Dongsoo
    • KDI Journal of Economic Policy
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    • v.28 no.2
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    • pp.97-129
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    • 2006
  • This study investigates whether dynamic loan loss provisioning is necessary in Korean banking environments. Under the dynamic provisioning rule banks are required to accumulate additional reserves to general and specific provisionings in preparation for expected loan losses until maturity. This provisioning is most effective in the case that banks tend to recognize less loan losses in the business upturns and/or in the periods of increasing profits. The empirical study, however, shows that banks support procyclicality of loan loss privisioning and earning smoothing behavior over profit fluctuations. These findings suggest that Korea would not seriously need the introduction of dynamic loan loss provisioning. But this policy implication does not seem robust in view that the recent experience shows the countercyclicality of loan loss provisioning practices and negative correlation between earnings and provisioning after financial restructuring was completed. This result is partly attributable to vigorous shareholder activism because of high foreign ownership of most commercial banks. Once it is true that bank management is more interested in short-term performances, current loan loss provisioning would have attributes of impairing capital adequacy, hence strengthening loan loss provisiong requirements.

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Study on the Compared between u-Learning and e-Learning based SCORM (SCORM 기반 u-Learning과 e-Learning 비교연구)

  • Choi, Sung;Ryu, Gab-Sang
    • Proceedings of the Korea Society of Information Technology Applications Conference
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    • 2006.06a
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    • pp.495-505
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    • 2006
  • IT기술기반 교육시스템은 인터넷 등장 이전에도 가능성을 인정받아 지속적으로 개발되어 온 분야이며, 교육공학과의 연계로 지식 전날의 이론체계로 각광을 받고 있다. 사이버교유도 인터넷이전부터 다양한 통신방법을 응용하여 개발되었고, 최근 인터넷을 통하여 사이버 교육시스템은 완벽한 기술기반을 갖추게 되였다. 그러나 IT기술의 급격한 변화로 사이버교육시스템은 계속하여 신기술 변화에 적용해야만 한다. 현재 정보통신기술의 변화는 방송 통신망의 융합, 브로드 밴드 네트워킹, 스마트 디바이스의 다양화, 멀티미디어 기술의 고도화로 요약된다. 이 기술의 종합한 작용으로 유비쿼터스 사회의 기반으로 진화되고 있다. 그래서 e-Learning 분야도 기존 인터넷기반 시스템과는 달리 차세대 온라인교육시스템으로 친화되고 있다. IT융합가술 기반의 온라인 교육시스템은 각종 국제표준단체에서 표준안이 제시되고 있다. e-Learning 시스템이란 선기술 기반을 반영한 표준기술을 사용하는 온라인교육시스템을 포괄하는 개념이다. 본 연구에서는 e-Learning 시스템과 유비쿼터스 기술을 반영한 e-Learning을 비교하였다. 그리고 u-Learning 시스템의 기술정립과 EOD(Education On Demand) 시스템에 대하여 연구하였다. 1. u-Learning 정의 정보산업분야를 비롯한 문화, 교육 등 모든 분야에서 유비퀴터스라는 수식어가 붙어 다니고 있다. e- Learning 교육 업계에 따르면 10년 후에는 유비쿼터스는 대중화가 될 것이며, 부가가치 규모는 100조 원에 이를 것으로 추정된다. 그래서 교육산업도 주변 환경이 아날로그 방식에서 IT 기반에 의한 디지털 환경으로 변화되고 있다. 또한 e러닝, T러닝, m러닝, u러닝 등의 용어가 생성되고 있다.키지에어컨에서 사용되고 있는 밀폐형 압축기에 대해서 그림 2에서 나타내고 있는 냉방능력 10tons(120,000Btu/h) 이하를 중심으로 상기의 최근 기술 동향을 간략하게 소개하고자 한다.질표준의 지표성분으로 간주되는 진세노사이드의 절대함량과 그 성분조성 차이에 따른 임상효과의 차별성이 있는지에 대한 검토와, 특히 최근 실험적으로 밝혀지고 있는 사포닌 성분의 장내 세균에 의한 생물전환체의 인체 실험을 통한 효과 검정이 필요하다. 나아가서는 적정 복용량의 설정과 이와 관련되는 생체내 동태 및 생체이용율(bioavilability)에 관한 정보가 거의 없으므로 이것도 금후 검토해야 할 과제로 사료된다. 인삼은 전통약물로서 오랜 역사성과 그동안의 연구결과에 의한 과학성을 가지고 있으므로 건강유지와 병의 예방 및 회복촉진을 위한 보조요법제 또는 기능성 식품으로써의 유용성이 있는 것으로 판단된다. 앞으로 인삼의 활용성 증대를 위해서는 보다 과학적인 임상평가에 의한 안전성 및 유효성 입증과 제품의 엄격한 품질관리의 필요성이 더욱 강조되어야 할 것이다.xyl radical 생성 억제 효과를 보여 주었다. 본 실험을 통하여 BHT 를 제외하고 전반적으로 세포 수준에서의 oxidative stress 에 대한 억제 효과를 확인해 볼 수 있었으며 특히 수용성 항산화제들에서 두드러진 효과를 보여 주었다. 제공하여 내수기반 확충에도 노력해야 할 것 이다.있었다., 인삼이 성장될 때 부분적인 영양상태의 불충분이나 기후 등에 따른 영향을 받을 수 있기 때문에 앞으로 이에 대한 많은 연구가 이루어져야할 것으로 판단된다.태에도 불구하고 [-wh]의미의 겹의문사는 병렬적 관계의 합성어가 아니라 내부구조를 지니지 않은 단순한 단어(minimal $X^{0}$<

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Adaptations and Physiological Characteristics of Three Chenopodiaceae Species under Saline Environments (명아주과 3종 식물의 염 환경에 대한 적응특성의 비교)

  • 송승달;김진아;추연식;배정진;김인숙;추보혜;이인중
    • The Korean Journal of Ecology
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    • v.25 no.2
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    • pp.101-107
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    • 2002
  • Three species of Chenopodiaceae, i.e. Suaeda japonica, Salicomia herbacea, Beta vulgaris var. cicla, were investigated to compare the physiological characteristics through inoic balances and osmoregulations under different environmental salt gradients. Plats were harvested in two weeks from treatments with salt gradients (0, 50, 100, 200 and 400 mM NaCl) and mineral nutrition gradients(1/1, 1/5, 1/10 dilutions of Hoagland solution). Plants were analyzed for growth responses, ionic balances, osmolalities, conductivities, glycinebetaine and proline contents quantitatively. Three plants of Chenopodiaceae accumulated slats into tissues unlike some salt sensitive species, and showed unique adaptation patterns to overcome saline environments, i.e. strong growth stimulation for Salicomia herbacea, growth negative tolerance for Suaeda japonica, and growth positive tolerance for Beta vulgaris var. cicla. The absorption of inorganic Ca/sup 2+/ ions was inhibited remarkably due to the excess uptake of Na+ with increasing salinity. The K+ content in plants was significantly reduced with increasing salinity. Total nitrogen content was reduced as mineral nutritions and salinity increased. Conductivity and osmolality increased with increasing salinity regardless of mineral nutritions. The ranges of glycinebetaine and proline contents were 0.2∼2.5 μM/g plant water and 0.1∼0.6μM/g plant water, respectively.