• The Korean Journal of Mycology
• /
• v.22 no.3
• /
• pp.216-221
• /
• 1994

As a part of studies on the fungal flora of Korea, authors have collected over 60 higher fungi specimens during summer season in 1993 in Mt. Hungjung which was located in eastern part of Korea. Among them two genera are new to Korea: Neobulgaria Petrak and Melastiza Boudier. Following five species are recorded for the first time in Korea: Psilocybe xeroderma Huijsm, Galerina vittaeformis (Fr.) Singer var. vittaeformis f. vittaeformis (Fr.) Singer, Gyromitra infula (Schaeffer ex Fries) Quelet, Neobulgaria pura (Fries) Petrak and Melastiza chateri (W. G. Smith) Boudier, for which Korean common names are designated in this present paper. All color names and terms within quotation marks are taken from Kornerup and Wanscher 1983, Methuen handbook of colour. The specimens are all deposited in the RDAGB's herbarium.

• Journal of Korea Game Society
• /
• v.4 no.3
• /
• pp.29-42
• /
• 2004

With the development of hardware and 3D graphic technologies since the 1990s, video games have been evolving in the direction in which they wholly pursue illusions and movie formats, and thus they are considered to be media centered on spectacles. However, video games, due to their inherent characteristics, cannot be transparent media like the existing spectacular entertainments centering on optical illusions. In their structure, there can be found elements that continually disillusion players from visions. Strictly speaking, players are not lost in visions, but are kept a certain distance from internal contexts. Games rely not on illusion but on contracts with players which are similar to a kind of convention, clearing internal imperfections. This paper aims to identify and analyze disillusioning elements and discuss theatrical contacts between players and games. The purpose of this paper is to reconsider the awareness of video games as a spectacle entertainment and to help discover future directions for game culture.

• Analytical Science and Technology
• /
• v.17 no.6
• /
• pp.443-453
• /
• 2004

Toluene is currently used as a major organic solvent of glues which are abused by the youngster for its hallucinogenic effect. In this study, toluene determination method using headspace gas chromatography (HS-GC) in the biological fluids like blood, urine and saliva of glue sniffers was validated and related uncertainties were estimated. LOD of $0.01{\mu}g/mL$ in saliva and LOQ of $0.1{\mu}g/mL$ in blood were the highest among LODs and LOQs in urine, blood and saliva. Other performance characteristics such as linearity, working range, accuracy, precision and recovery were also measured. The uncertainty at toluene concentration of $1{\mu}g/mL$ was estimated to be 0.13, 0.09 and $0.17{\mu}g/mL$ for blood, urine and saliva, respectively, and the uncertainty contribution from the least linear regression was dominant at the lower concentration of toluene.

• Proceedings of the Plant Resources Society of Korea Conference
• /
• 2019.10a
• /
• pp.6-6
• /
• 2019

대마는 인류가 이용해 온 가장 오래된 약제 중 하나로 그 원산지는 중앙아시아와 남아시아이다. 식물분류학적으로 대마속 일년생 식물로서 Cannabis sativa, Cannabis indica, Cannabis ruderalis 3종이 있으며, 우리나라에서 재배되고 있는 종은 Cannabis sativa이다. 대마 재배의 역사는 인류의 시작과 그 궤를 같이하며, 동 서양을 막론하고 고대 문명에서 대마에 대한 기록을 쉽게 찾아볼 수 있다. 기록에 의하면 병의 치료나 심리적 치유 및 신에게 제사를 올릴 때 제사장이 사용한 것으로 알려져 있다. 대마의 약효에 대하여는 B.C. 2737년 중국의 신농황제시대의 기록에 관절염과 통증등 의료목적으로 사용했던 최초의 기록이 있으며 본초강목과 동의보감에 저술되어 있다. 우리나라의 대마에 관한 문헌 기록은 삼국지 '위지동이전', 삼국사기 '동성왕편'과 삼국유사에 삼베를 사용한 기록이 있는 것으로 미루어 봤을 때 대마재배의 역사는 삼국시대 이전으로 볼 수 있다. 우리 민족은 생활 속에서 대마를 즐겨 사용하였으며 삼베로 의복과 멍석, 행주 그리고 칠공예품이나 신발등을 만들어 사용하였으며, 죽음에 이르러 삼베옷을 수의로 사용하였다. 대마의 용도는 뿌리, 줄기, 잎, 꽃대 그리고 씨앗까지 다양하게 이용된다. 전통적으로 줄기의 껍질을 이용한 섬유제품이 있으며 실, 의복 및 밧줄등이 있다. 대마 줄기의 속대는 종이, 건축자재, 연료로 사용된다. 씨앗의 경우 식품과 조류의 먹이, 생약으로 이용되고 씨앗의 기름은 연료, 화장품, 맛사지 오일등으로 사용되고 있다. 환각성분이 있어 마리화나 원료로 사용되는 꽃대와 잎은 의약품의 원료로 주목받고 있다. 대마에 관한 최초의 논문은 1843년에 Cannabis indica의 약효에 관한 것으로 보고되었다. 1850년부터 1937년까지 미국의 약전은 대마를 100가지 이상의 질병에 효과가 있는 주요 의약품으로 기재하고 있다. 세계적으로 여러 가지 이유로 대마를 의료 응용과 연구 및 사용을 제한하여 대마에 관한 연구가 침체되었다. 대마의 의학연구는 대마의 약효성분인 칸나비노이드의 발견과 그 구조 및 약효에 관한 연구가 시작되면서 1960년대부터 증가하였으며 2000년 이후에는 칸나비노이드 및 칸나비디올의 다양한 의학적 효과가 밝혀지면서 급격히 증가하고 있다. 대마에 포함된 성분의 의학적 효과가 입증되면서 대마 사용을 합법화한 국가가 증가하면서 대마 산업이 급부상하고 있으며, 의료용뿐만 아니라 기호용, 식품용, 그리고 주류 및 음료시장까지 확대되고 있다. 우리나라도 2019년 3월 질병 치료 목적 대마성분 의약품을 제한적으로 허용하는 마약류 관리에 관한 법률 일부 개정안이 시행되면서 의료용 대마에 관한 연구와 산업화에 관심이 증가하는 추세이다.

• Annual Conference on Human and Language Technology
• /
• 2023.10a
• /
• pp.432-436
• /
• 2023

초거대언어모델(LLM)의 도래에 따라 다양한 과업들이 도메인 관계 없이 제로샷으로 추론이 가능해짐에 따라서 LLM이 다양한 산업분야에 적용되고 있다. 대표적으로 ChatGPT와 GPT-4는 상용 API로 서비스를 제공하여 용이한 서비스 접근으로 다양한 이용층을 끌어들이고 있다. 그러나 현재 상용 API로 제공되고 있는 ChatGPT 및 GPT-4는 사용자의 대화 내역 데이터를 수집해 기업의 보안 문제를 야기할 수 있고 또한 생성된 결과물의 환각 문제로 인한 기업 문서의 신뢰성 저하를 초래할 수 있다. 특히 LLM 생성 글은 인간의 글과 유사한 수준으로 유창성을 확보한만큼 산업현장에서 LLM 작성 글이 판별되지 못할 경우 기업 활동에 큰 제약을 줄 수 있다. 그러나 현재 한국어 LLM 작성 글 탐지 서비스가 전무한 실정이다. 본 논문에서는 한국어 초거대언어모델 작성 글 판별기: KoCheckGPT 를 제안한다.KoCheckGPT는 산업현장에서 자주 사용되는 문어체, 개조식 글쓰기로 작성된 문서 도메인을 목표로 하여 글 전체와 문장 단위의 판별 정보를 결합하여 주어진 문서의 LLM 작성 여부를 효과적으로 판별한다. 다국어 LLM 작성 글 판별기 ZeroGPT와의 비교 실험 결과 KoCheckGPT는 우수한 한국어 LLM 작성 글 탐지 성능을 보였다.

• Journal of the Korean Society of Radiology
• /
• v.83 no.4
• /
• pp.945-950
• /
• 2022

Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is a common autoimmune encephalitis that is noted to be a severe but treatable disease entity. Patients with anti-NMDAR encephalitis often develop psychotic symptoms, including delusions, hallucinations, and paranoia, as well as memory impairment and persistent loss of attention. However, MRI findings in such patients show no abnormalities in most cases. Although typical brain abnormality features, known as T2 hyperintensities, involve the brain parenchyma and contrast enhancement at the cerebral cortex or overlying meninges, isolated leptomeningeal enhancement has been rarely reported in anti-NMDAR encephalitis. Herein, we report a patient with anti-NMDAR encephalitis who presented with isolated leptomeningeal enhancement, additionally showing the diagnostic value of contrast-enhanced fluid-attenuated inversion recovery imaging.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
• /
• v.1 no.1
• /
• pp.130-147
• /
• 1990

This study intended to investigate the characteristics of adolescent drug user in Korea. A questionnaire on adolescent drug use was administered to 1st or 2nd grade 898 students (465 males, 433 females) from 9 senior high schools in Seoul area. The extent of current using six representative drugs such as cigarettes, alcohol, chemical substance inducing hallucination(e,g., thinner, bond etc.), psychostimulant, hypnotic and minor tranqulizer was self-reported. Also their psychological distress, self-concept and individual-related variables such as academic grade, deviant behavior, drug-using peers, the perceived availability of drugs, the degree of family discipline, and the perceived parents' attitude for drinking and smoking were surveyed. Subjects were grouped into six(male) or five(female) subgroups (nonuser, simple experiencer, one kind of drug user, two kinds of drugs user, three kinds of drugs user(male only), minor tranqulizer user) to their extent of drug use. Then ANOVA procedure performed for group comparison of their psychological distress, self-concept and individual-related variables. The results showed that the most popular drugs among adolescents in Korea were cigarettes and alcohol. Minor tranqulizer was used by about 2.8% of male and 7.41% of female subjects. In general abusers showed lower academic grade, more deviant experiences, having more drug-using peers, higher degree of psychological distress, and lower postitive self-concept than nonuser group. According to the results of discriminant analysis, hostility and deviant behavior were reliable predictive variables that distinguished abuser group from nonuser group among the associated variables in this study. These results suggest that some common factors affect drug use of Korean high school students : high school students who have many common risk factors could be abusers more easily. These findings supported risk factor theory that the extent of drug use of adolescents might be associated with general maladjustment in everyday life.

• Sleep Medicine and Psychophysiology
• /
• v.7 no.2
• /
• pp.115-119
• /
• 2000

Objectives Summary: A 20-year-old man was presented with a history of difficult waking for 10 years. He suffered from morning headache, chronic fatigue and mild daytime sleepiness but had no history of irresistible sleep attack, cataplexy, hypnagogic hallucination or sleep paralysis. Methods: Night polysomnography (PSG), multiple sleep latency test (MSLT) and HLA-typing were carried out. Results: The PSG showed short sleep latency (4.0 min) and REM latency (2.5 min), increased arousal index (15.7/hour), periodic limb movements during sleep (PLMS index=8.1/hr) with movement arousal index 2.1/hr and normal sleep efficiency (97.5%). The MSLT revealed normal sleep latency (15 min 21 sec) and 4 times sleep-onset REM (SOREM). HLA-typing showed DQ6- positive, that corresponded at the genomic level to the subregion DQB1*0601, which was different from the usual locus in narcolepsy patients (DQB1*0602 and DQA1*0102). Conclusion: Differential diagnosis should be made with circadian rhythm disorder and other causes of primary waking disorder. The possibility of a variant type of narcolepsy could be suggested with an unusual clinical manifestation and a new genetic marker.

• Korean Journal of Psychosomatic Medicine
• /
• v.20 no.2
• /
• pp.105-111
• /
• 2012

Objectives : We investigated the prevalence and composite score of the neuropsychiatric symptoms in patients with mild cognitive impairment(MCI), and dementia of Alzheimer's type(AD). The aim of this study is to analyze the correlation between the result of Korean Neuropsychiatric Inventory(K-NPI) and cognitive function. Methods : A total of 163 patients diagnosed with MCI or AD was divided into three groups(55 MCI patients, 56 dementia patients with mild stage, and 52 dementia patients with moderate, severe stage). We examined neuro-psychiatric symptoms by K-NPI and compared the prevalence and composite score of each subdomain in K-NPI among three groups. Results : The most common symptoms in the MCI group were depression/dysphoria, sleep/night-time behavior, anxiety, and irritability/lability. In mild AD group, the most frequent disturbance was agitation/aggression, depression/dysphoria, anxiety, apathy/indifference, and sleep/night-time behavior. In moderate to severe AD group, the most frequent disturbance was apathy/indifference, depression/dysphoria, agitation/aggression, and delusion. The frequencies of delusion, hallucination, agitation/aggression, apathy/indifference, aberrant motor behavior, appetite/eating change were statistically significant. The total NPI score showed a negative correlation with MMSE-KC and a positive correlation with GDS. Conclusions : Neuropsychiatric symptoms are common features of MCI and AD. These symptoms observed in MCI are similar to those of mild AD. Psychosis is most common in moderate to severe AD, leading to a faster rate of cognitive decline. Therefore, proper management according to the neuropsychiatric symptoms of MCI and three stages of dementia is needed.

• Korean Journal of Medicinal Crop Science
• /
• v.13 no.4
• /
• pp.190-193
• /
• 2005

Hemp is cultivated to produce fiber and seeds for extracting vegetable oil. This study was carried out to obtain reliable data on fatty acid profile including ${\gamma}-linolenic$ acid (GLA) in seeds of hemp accessions with regard to suitability for both human nutrition and pharmaceutical purposes. The ratio of unsaturated fatty acid including ${\alpha}-linolenic$ acid were high but saturated fatty acid including palmitic acid were low in the seeds of hemp accessions, perilla and evening primrose. The ratio of GLA in fatty acid profile of evening primrose and hemp seeds were 12.5% and 2.1 %, respectively but not detected in perilla seeds. In the fatty acid profile of hemp seeds accessions, the range and coefficient of variation of GLA were $0.8%{\sim}3.8%$ and 42.9%, respectively which are highest among the fatty acid. Among the major characteristics and fatty acid ratios, flowering date and ${\alpha}-linolenic$ acid showed highly positive correlation but not showed any significant correlation between THC (Tetrahydrocannabinol) and any fatty acids. Among the fatty acid ratios, negative correlation were showed between palmitic acid and ${\gamma}-linolenic$ acid, and showed highly negative correlation between oleic acid and ${\alpha}-linolenic$ acid, linoleic acid and a-linolenic acid. The accessions of high GLA ratio were originated from Europe including Central Russia, and were short in flowering date and stem height.