• Korean Journal of Food Science and Technology
• /
• v.34 no.5
• /
• pp.856-861
• /
• 2002

Surface-modified powders were produced by hybridization system using core freeze-dried lactic acid bacteria (Lactobacillus acidophilus ATCC 43121) and enteric coating materials. Scanning electron microscopy showed that the surface of freeze-dried lactic acid bacteria changed to smooth round shape during surface reforming process, although no significant physical damages affecting the activity of the lactic acid bacteria were observed based on viability and salt-tolerance tests. Signigicant difference was not found in acid tolerance test probably due to the inherent acid tolerance of L. acidophilus ATCC 43121. Significantly improved heat tolerance was obtained by surface modification process. Among the tested coating materials, Sureteric showed a higher surface- reforming ability than Eudragit S100 and L100-55. Core : coating ratio agent of 9 : 1 (w/w) with rotor speed of 15,000 rpm for 3 min were determined to be optimum conditions for the process.

• Journal of Periodontal and Implant Science
• /
• v.28 no.2
• /
• pp.219-237
• /
• 1998

Numerous bone graft materials have been used in Periodontics, in an attempt to reach the main goal of periodontal therapy, i.e. the regeneration of periodontal tissue lost due to destructive periodontal diseases. The present study investigates the effect of composite graft of DFDB and Calcium sulfate with and without Calcium sulfate barrier in Periodontal 1-wall intrabony defects in dogs. Following the initiation of general anesthesia by I.V. administration of 40mg/Kg of Pentobabital, second premolar was extracted and full thickness flap elevated. The crown portion of premolars was removed. Exposed root canals were sealed with Caviton and covered completely with flap. After the healing period of 8 weeks, the surgical sites were re-opened and 1-wall intrabony defects were created, and treated with flap operation alone(control group), with composit graft of 80% DFDB and 20% Calcium sulfate(Experimental group 1), with composite graft of DFDB and calcium sulfate with calcium sulfate membrane( Experimental group 2). Healing response was histologically observed after 8 weeks and the results were as follows : 1. New bone formation was 70 % in the control group, 93 % in the Experimental group I, 89 % in the Experimental group II. There was a no differences between Experimental groups. 2. New cementum formation was not significantly different between control and two Experimental groups. 3. The length of connective tissue adhesion was 30 % in the control, 7% in the Experimental group I and 11 % in the Experimental group II. 4. After 8weeks, calcium sulfate was completely resorbed, while DFDB particle remained. These results suggest that the use of composite graft of allogenic DFDB and Calcium sulfate with and without Calcium sulfate barrier in periodontal 1 wall intrabony defects have little effect on connective tissue adhesion, but has beneficial effect on new alveolar bone and new cementum formation, and prevent downgrowth of epithelium and connective tissue effectively.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
• /
• 2002.11a
• /
• pp.477-480
• /
• 2002

Si-O-C(-H) thin film with a tow dielectric constant were deposited on a P-type Si(100) substrate by an inductively coupled plasma chemical vapor deposition (ICPCVD). Bis-trimethylsilymethane (BTMSM, H$_{9}$C$_3$-Si-CH$_2$-Si-C$_3$H$_{9}$) and oxygen gas were used as Precursor. Hybrid type Si-O-C(-H) thin films with organic material have been generated many voids after annealing. Consequently, the Si-O-C(-H) films can be made a low dielectric material by the effect of void. The surface characterization of Si-O-C(-H) thin films were performed by SEM(scanning electron microscope). The characteristic analysis of Si-O-C(-H) thin films were performed by X-ray photoelectron spectroscopy (XPS).

• Korean Chemical Engineering Research
• /
• v.49 no.4
• /
• pp.465-469
• /
• 2011

In this study, poly(ethyleneoxide) and poly(ethylene imine) polymer blends containing fumed silica fillers were studied in order to enhance the ion conductivity and interfacial properties. Lithium perchlorate ($LiClO_4$) as a salt, and silica($SiO_2$) as the inorganic filler were introduced into the polymer composite electrolyte composites and the composites were examined to evaluate their ionic conductivity for a possibility test of electrolyte application. As the diameter of semicircle in an impedance test became smaller, ionic conductivity of composite electrolytes had been enhanced by addition of 20 wt% silica filler. However, the conductivity was not greatly changed over 20 wt% content because the silica was sufficiently saturated in the polymer electrolytes. Diffraction peaks of PEO became weaker with the addition of inorganic fillers using XRD analysis. It showed that a crystallinity was proportionally reduced by increasing filler contents. The morphology of composite electrolyte films has been investigated by SEM. The heterogeneous morphology which silica was evenly dispersed by the strong adhesion of PEI was shown at higher contents of silica.

• Polymer(Korea)
• /
• v.24 no.3
• /
• pp.389-398
• /
• 2000

Transparent, abrasion resistant coatings with 4~13 ${\mu}{\textrm}{m}$ thickness were prepared by spin-coating on polycarbonates with organic/inorganic hybrid solutions, followed by UV curing and heat treatment at 12$0^{\circ}C$ for 12 hours. The coating solutions were composed of inorganic phase and organic phase in 0:100, 20:80, 30:70, 50:50, 80:20 wt% ratios, respectively, mixed with photoinitiator, senaitizer and surfactant. The inorganic phase was formed by sol-gel reaction of TEOS and silane coupling agent MPTMS in 1 : 2 or 2 : 1 molar ratios, the organic phase consisted of difunctional urethane acrylate oligomeric resin, multifunctional acrylate TMPTA and HDDA in 4 : 3 : 3 wt% ratio. The coating systems were investigated by FT-IR, $^{29}$ Si-NMR spectra. In addition, TGA/DSC for thermal analysis and SEM, AFM observation for coated surface were examined. Gererally, the homogeneity of phases, the surface smoothness of coating and abrasion resistance were improved with the higher content of inorganic component. Namely, coating system with below 10 $\AA$ surface roughness and T$_{g}$ of 15$0^{\circ}C$ showed only 10% decrease in light transmittance after abrasion test, whereas uncoated polycarbonate substrate exhibited 46% decrease..

• Korean Journal of Soil Science and Fertilizer
• /
• v.38 no.5
• /
• pp.287-293
• /
• 2005

In this work, to develop soil inoculant which maintains stable viable cells and normalized quality, studies on micro-encapsulation with bacteria and yeast cells were performed by investigating materials and methods for micro-encapsulation as well as variation and stability of encapsulated cells. Preparation of capsule was conducted by application of extrusion system using micro-nozzle and peristaltic pump. K-carragenan and Na-alginate were selected as best carrier for gelation among K-carageenan, Na-alginate, locust bean gum, cellulose acetate phthalate (CAP), chitosan and gelatin tested. Comparing the gels prepared with Bacillus sp. KSIA-9 and carriers of 1.5% concentration, although viable cell of K-carragenan and Na-alginate was six times higher than those of other, Na-alginate was finally selected as carrier for gelation because it is seven times cheaper than K-carragenan. The gel of 1.5% Na-alginate was also observed to have the best morphology with circular hardness polymatrix and highest viable cell. When investigating the stability of encapsulated cells and the stabilizer effect, free cells were almost dead within 30 or 40 days whereas encapsulated cells decreased in 10% after 30 days and 15-30% even after 120 days. As stabilizer for maintaining viable cell, both 1% starch and zeolite appeared to possess the level of 70-80% cell for bacteria and yeast until after 120 days.

• Proceedings of the Korean Vacuum Society Conference
• /
• 2010.02a
• /
• pp.406-406
• /
• 2010

일반적으로, 나노스케일의 MOS 소자에서는 게이트 절연체 두께가 감소함에 따라 tunneling effect의 증가로 인해 PID (plasma induced damage)로 인한 소자 특성 저하 현상을 감소하는 추세로 알려져 있다. 하지만 요즘 많이 사용되고 있는 high-k 게이트 절연체의 경우에는 오히려 더 많은 charge들이 trapping 되면서 PID가 오히려 더 심각해지는 현상이 나타나고 있다. 이러한 high-k 게이트 식각 시 현재는 주로 Hf-based wet etch나 dry etch가 사용되고 있지만 gate edge 영역에서 high-k 게이트 절연체의 undercut 현상이나 PID에 의한 소자특성 저하가 보고되고 있다. 본 연구에서는 이에 차세대 MOS 소자의 gate stack 구조중 issue화 되고 있는 metal gate 층과 gate dielectric 층의 식각공정에 각각 중성빔 식각과 중성빔 원자층 식각을 적용하여 전기적 손상 없이 원자레벨의 정확한 식각 조절을 해줄 수 있는 새로운 two step 식각 공정에 대한 연구를 진행하였다. 먼저 TiN metal gate 층의 식각을 위해 HBr과 $Cl_2$ 혼합가스를 사용한 중성빔 식각기술을 적용하여 100 eV 이하의 에너지 조건에서 하부층인 $HfO_2$와 거의 무한대의 식각 선택비를 얻었다. 하지만 100 eV 조건에서는 낮은 에너지에 의한 빔 스케터링으로 실제 패턴 식각시 etch foot이 발생되는 현상이 관찰되었으며, 이를 해결하기 위하여 먼저 높은 에너지로 식각을 진행하고 $HfO_2$와의 계면 근처에서 100 eV로 식각을 해주는 two step 방법을 사용하였다. 그 결과 anistropic 하고 하부층에 etch stop된 식각 형상을 관찰할 수 있었다. 다음으로 3.5nm의 매우 얇은 $HfO_2$ gate dielectric 층의 정확한 식각 깊이 조절을 위해 $BCl_3$와 Ar 가스를 이용한 중성빔 원자층 식각기술을 적용하여 $1.2\;{\AA}$/cycle의 단일막 식각 조건을 확립하고 약 30 cycle 공정시 3.5nm 두께의 $HfO_2$ 층이 완벽히 제거됨을 관찰할 수 있었다. 뿐만 아니라, vertical 한 식각 형상 및 향상된 표면 roughness를 transmission electron microscope(TEM)과 atomic force microscope (AFM)으로 관찰할 수 있었다. 이러한 중성빔 식각과 중성빔 원자층 식각기술이 결합된 새로운 gate recess 공정을 실제 MOSFET 소자에 적용하여 기존 식각 방법으로 제작된 소자 결과를 비교해 본 결과 gate leakage current가 약 one order 정도 개선되었음을 확인할 수 있었다.

• Korean Chemical Engineering Research
• /
• v.59 no.1
• /
• pp.42-48
• /
• 2021

Zn and Al added LiNi0.85Co0.15O2 cathode materials were synthesized to improve electrochemical properties and thermal stability using a solid-state route. Crystal structure, particle size and surface shape of the synthesized cathode materials was measured using XRD (X-ray diffraction) and SEM (scanning electron microscopy). CV (cyclic voltammetry), first charge-discharge profiles, rate capability, and cycle life were measured using battery cycler (Maccor, series 4000). Strong binding energy of Al-O bond enhanced structure stability of cathode material. Electrochemical properties were improved by preventing cation mixing between Li+ and Ni2+. Large ion radius of Zn+ increased lattice parameter of NC cathode material, which meant unit-cell volume was expanded. NCZA25 showed 80% of capacity retention at 0.5 C-rate during 100 cycles, which was 12% higher than that of NC cathode. The discharge capacity of NCZA25 showed 104 mAh/g at 5 C-rate. NCZA25 achieved 36 mAh/g more capacity than that of NC cathod. NCZA25 cathode material showed excellent rate capability and cycling performance.

• Proceedings of the Korea Water Resources Association Conference
• /
• 2020.06a
• /
• pp.21-22
• /
• 2020

낙동강 하굿둑(이하 하굿둑)은 1987년 부산 사하구와 강서구 사이에 건설되어 하류 지역의 바닷물 유입을 막아 부산, 울산, 경남 등에 안정적으로 생활·농업·공업 등의 분야에 용수를 공급하는 역할을 해왔다. 현재, 하굿둑의 수문은 낙동강 상류로부터 하류로 흘러내려오는 민물(담수)을 방류하기 위해서만 하굿둑 수문을 개방하고 있다. 하구는 하천의 담수와 바다의 염수가 서로 만나는 구역으로 바닷물과 염수의 밀도차에 의한 혼합으로 자연상태의 하구에서는 담수와 염수가 섞이는 기수역이 형성되며, 이러한 특성으로 하구 인근의 지역에서는 일반적인 하천 및 해양, 연안과는 분명히 구별되는 생태계가 조성된다. 하굿둑 건설이후 바닷물(해수)과 민물(담수)이 만나는 낙동강 어귀에 기수생태계가 사라지면서 바닷물이 유입될 수 있도록 하여 생태계를 복원해야 한다는 필요성이 제기되어 왔으며, 하굿둑이 지역에 기여해온 사실은 분명하나 하굿둑으로 인해 생태계 단절이 발생하고 기수생태계가 파괴되었기 때문에 이를 해결하기 위해서는 하굿둑을 개방하여 과거 기수생태계를 복원해야 한다는 목소리가 높아지고 있다. 이에 따라 정부에서는 하굿둑의 기수생태계 복원을 위해서 관계기관 합동으로 의사결정을 하고 효율적인 개방 방안을 모색하는 실무협의회를 구성하여 운영 중이고, 실무협의회 논의를 통해 5개 주요 관계기관(환경부, 국토부, 해양수산부, 부산광역시, K-water) 공동으로 "낙동강하굿둑 운영개선 및 생태복원 방안 연구용역"을 추진 중이다. 2018년 1단계 용역이 완료되었으며, 2019년부터 2단계 연구용역을 추진 중이고 하굿둑 개방의 수준별로 각종 영향을 검토한 후 대책을 마련하여 기수생태계 복원 방안을 수립하는데 그 목적이 있다. 2단계 연구용역에서는 과학적이고 합리적인 기수생태계 복원방안 마련을 위해서 실제로 해수를 유입시키는 3차례의 실증실험 및 수리모형실험 등을 추진한다. 기존 연구들에서도 수문개방에 따른 해수유입 영향에 대해 모델링을 통해서 분석했지만 이는 검증이 이루어지지 않은 결과로 이번 용역에서는 실제 해수를 유입시키고 염분의 침투 및 각종 수생태 영향을 모니터링 한 후 그 결과를 반영하여 모델링을 고도화하고 있다. 최종적으로 고도화된 모델링 결과를 기반으로 기수생태계 조성 방안별로 염분, 수질, 수생태, 침퇴적 등 각종 분야에 대한 정확한 영향을 분석하고 이에 대한 대책을 포함하여 최종적으로 바람직한 기수생태계 복원 방안을 제시할 계획이다. 기수생태계 복원 방안이 계획에만 그치지 않고 실행으로 연결시키기 위해서 필요성에 대한 이해를 바탕으로 공감대를 형성해 나아가고 있으며 지역주민, 전문가, 관계기관 등 민(民)·관(官)·학(學) 다양한 의견을 수렴하여 하구지역내 수량-수질-수생태를 종합적으로 고려하여 복원 방안을 마련 후 사회적인 합의를 추진하여 확정할 예정이며, 하구의 안정적인 관리를 위해 AI 등 4차 산업혁명기술을 적극 적용하는 스마트한 하구물관리(Smart Estuary Watershed Management)"를 활용한 "하구통합물관리" (Estuary Integrated Watershed Management) 등 과학적인 관리를 추진할 계획이다.

• Clinical and Experimental Pediatrics
• /
• v.52 no.4
• /
• pp.458-463
• /
• 2009

Purpose : Schizencephaly is a uncommon congenital brain anomaly characterized by congenital clefts spanning the cerebral hemispheres from pial surface to lateral ventricles and lined by gray matter. In this study, we investigated the clinical manifestation and radiologic findings of pediatric schizencephaly. Methods : The data of 13 patients who were diagnosed with schizencephaly in Severance Childrens Hospital and Yongdong Severance Hospital from January 2005 to December 2007 were analyzed retrospectively. Results : The mean age at diagnosis was $9.08{\pm}2.67$ months old and ranged from 1 to 30 months. The ratio of male to female patients was 3.33:1. Five (38.5%) patients had bilateral clefts, while 8 (61.5%) had unilateral clefts. Five (38.5%) patients had closed lip clefts, and 4 (30.8%) had opened lip clefts. Four (30.8%) patients had multiple clefts. Associated anomalies showed in all cases. The clinical features consisted of mild unilateral weakness in 7 (53.8%) cases and a hemiparesis was present in 3 (23.1%) patients. A tetraparesis was in 3 (23.1%) patients. There was no difference in motor deficit between unilateral and bilateral clefts. Delayed development was observed in all cases. Epilepsy was present in 7 (53.8%) patients, 5 patients with unilateral clefts and 2 patients with bilateral clefts. Three (42.8%) patients showed intractable seizures. Conclusion : Schizencephaly showed variable clinical manifestations and radiologic findings in association with the types and locations of the clefts. It is necessary to diagnose schizencephaly early and to detect the development of epilepsy. Intensive and large studies of the correlation of clinical outcomes and radiologic findings should be continued for more effective treatment.