• Title/Summary/Keyword: 호흡 위상

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Discrepancies between Calculated and Delivered Dose Distributions of Respiratory Gated IMRT Fields according to the Target Motion Ranges for Lung and Liver Cancer Patients (호흡연동방사선치료시 폐암과 간암환자의 병소 움직임 크기에 따른 선량분포 차이 분석)

  • Kim, Youngkuk;Lim, Sangwook;Choi, Ji Hoon;Ma, Sun Young;Jeung, Tae Sig;Ro, Tae Ik
    • Progress in Medical Physics
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    • v.25 no.4
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    • pp.242-247
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    • 2014
  • To see the discrepancies between the calculated and the delivered dose distribution of IMRT fields for respiratory-induced moving target according to the motion ranges. Four IMRT plans in which there are five fields, for lung and liver patients were selected. The gantry angles were set to $0^{\circ}$ for every field and recalculated using TPS (Eclipse Ver 8.1, Varian Medical Systems, Inc., USA). The ion-chamber array detector (MatriXX, IBA Dosimetry, Germany) was placed on the respiratory simulating platform and made it to move with ranges of 1, 2, and 3 cm, respectively. The IMRT fields were delivered to the detector with 30~70% gating windows. The comparison was performed by gamma index with tolerance of 3 mm and 3%. The average pass rate was 98.63% when there's no motion. When 1.0, 2.0, 3.0 cm motion ranges were simulated, the average pass rate were 98.59%, 97.82%, and 95.84%, respectively. Therefore, ITV margin should be increased or gating windows should be decreased for targets with large motion ranges.

Usefulness of Gated RapidArc Radiation Therapy Patient evaluation and applied with the Amplitude mode (호흡 동조 체적 세기조절 회전 방사선치료의 유용성 평가와 진폭모드를 이용한 환자적용)

  • Kim, Sung Ki;Lim, Hhyun Sil;Kim, Wan Sun
    • The Journal of Korean Society for Radiation Therapy
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    • v.26 no.1
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    • pp.29-35
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    • 2014
  • Purpose : This study has already started commercial Gated RapidArc automation equipment which was not previously in the Gated radiation therapy can be performed simultaneously with the VMAT Gated RapidArc radiation therapy to the accuracy of the analysis to evaluate the usability, Amplitude mode applied to the patient. Materials and Methods : The analysis of the distribution of radiation dose equivalent quality solid water phantom and GafChromic film was used Film QA film analysis program using the Gamma factor (3%, 3 mm). Three-dimensional dose distribution in order to check the accuracy of Matrixx dosimetry equipment and Compass was used for dose analysis program. Periodic breathing synchronized with solid phantom signals Phantom 4D Phantom and Varian RPM was created by breathing synchronized system, free breathing and breath holding at each of the dose distribution was analyzed. In order to apply to four patients from February 2013 to August 2013 with liver cancer targets enough to get a picture of 4DCT respiratory cycle and then patients are pratice to meet patient's breathing cycle phase mode using the patient eye goggles to see the pattern of the respiratory cycle to be able to follow exactly in a while 4DCT images were acquired. Gated RapidArc treatment Amplitude mode in order to create the breathing cycle breathing performed three times, and then at intervals of 40% to 60% 5-6 seconds and breathing exercises that can not stand (Fig. 5), 40% While they are treated 60% in the interval Beam On hold your breath when you press the button in a way that was treated with semi-automatic. Results : Non-respiratory and respiratory rotational intensity modulated radiation therapy technique absolute calculation dose of using computerized treatment plan were shown a difference of less than 1%, the difference between treatment technique was also less than 1%. Gamma (3%, 3 mm) and showed 99% agreement, each organ-specific dose difference were generally greater than 95% agreement. The rotational intensity modulated radiation therapy, respiratory synchronized to the respiratory cycle created Amplitude mode and the actual patient's breathing cycle could be seen that a good agreement. Conclusion : When you are treated Non-respiratory and respiratory method between volumetric intensity modulated radiation therapy rotation of the absolute dose and dose distribution showed a very good agreement. This breathing technique tuning volumetric intensity modulated radiation therapy using a rotary moving along the thoracic or abdominal breathing can be applied to the treatment of tumors is considered. The actual treatment of patients through the goggles of the respiratory cycle to create Amplitude mode Gated RapidArc treatment equipment that does not automatically apply to the results about 5-6 seconds stopped breathing in breathing synchronized rotary volumetric intensity modulated radiation therapy facilitate could see complement.

Evaluation of the Usefulness of the Self-developed Kw-infrared Reflective Marker in Non-coplanar Treatment (비동일면 치료 시 자체 제작한 Kw-infrared Reflective Marker의 유용성 평가)

  • Kwon, Dong-Yeol;Ahn, Jong-Ho;Park, Young-Hwan;Song, Ki-Won
    • The Journal of Korean Society for Radiation Therapy
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    • v.22 no.1
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    • pp.25-32
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    • 2010
  • Purpose: In radiotherapy that takes into account respiration using a RPM (Real time Position Management, Varian, USA) system, which can treat in consideration of the movement of tumor, infrared reflective markers supplied by manufacturers cannot obtain respiratory signal if the couch rotates at a certain angle or larger. In order to solve this problem, the author developed the 3D infrared reflective marker named 'Kw-marker' that can obtain respiratory signal at any angle, and evaluate its usefulness. Materials and Methods: In order to measure the stability of respiratory signal, we put the infrared reflective marker on the 3D moving phantom that can reproduce respiratory movement and acquired respiratory signal for 3 minutes under each of 3 conditions (A: $couch\;0^{\circ}$, a manufacturer's infrared reflective marker B: $couch\;0^{\circ}$, Kw-marker C: $couch\;90^{\circ}$, Kw-marker). By analyzing the respiratory signal using a breath analysis program (Labview Ver. 7.0), we obtained the peak value, valley value, standard deviation, variation value, and amplitude value. In order to examine the rotation error and moving range of the target, we placed a B.B phantom on the 3D moving phantom, and obtained images at a couch angle of $0^{\circ}$ and $90^{\circ}$ using OBI, and then acquired the X, Y and Z values (mm) of the ball bearing at the center of the B.B phantom. Results: According to the results of analyzing the respiratory signal, the standard deviation at the peak value was A: 0.002, B: 0.002 and C: 0.003, and the stability of respiration for amplitude was A: 0.15%, B: 0.14% and C:0.13%, showing that we could get respiratory signal stably by using the Kw-marker. When the couch rotated $couch\;90^{\circ}$, the mean rotation error of the ball bearing, namely, the target was X: -1.25 mm, Y: -0.45 mm and Z: +0.1 mm, which were within 1.3 mm on the average in all directions, and the difference in the moving range of the target was within 0.3 mm. Conclusion: When we obtained respiratory signal using the Kw-marker in non-coplanar treatment where the couch rotated, we could acquire respiratory signal stably and the Kw-marker was effective enough to substitute for the manufacturer's infrared reflective marker. When the rotation error and moving range of the target were measured, there was little difference, indicating that the displacement of the reflector movement in couch rotation is the cause of change in the scale and amplitude of respiratory signal. If the converted value of amplitude height according to couch angle is studied further and applied, it may be possible to perform non-coplanar phase-based gating treatment.

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Dosimetric Evaluation of Amplitude-based Respiratory Gating for Delivery of Volumetric Modulated Arc Therapy (진폭 기반 호흡연동 체적변조회전방사선치료의 선량학적 평가)

  • Lee, Chang Yeol;Kim, Woo Chul;Kim, Hun Jeong;Park, Jeong Hoon;Min, Chul Kee;Shin, Dong Oh;Choi, Sang Hyoun;Park, Seungwoo;Huh, Hyun Do
    • Progress in Medical Physics
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    • v.26 no.3
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    • pp.127-136
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    • 2015
  • The purpose of this study is to perform a dosimetric evaluation of amplitude-based respiratory gating for the delivery of volumetric modulated arc therapy (VMAT). We selected two types of breathing patterns, subjectively among patients with respiratory-gated treatment log files. For patients that showed consistent breathing patterns (CBP) relative to the 4D CT respiration patterns, the variability of the breath-holding position during treatment was observed within the thresholds. However, patients with inconsistent breathing patterns (IBP) show differences relative to those with CBP. The relative isodose distribution was evaluated using an EBT3 film by comparing gated delivery to static delivery, and an absolute dose measurement was performed with a $0.6cm^3$ Farmer-type ion chamber. The passing rate percentages under the 3%/3 mm gamma analysis for Patients 1, 2 and 3 were respectively 93.18%, 91.16%, and 95.46% for CBP, and 66.77%, 48.79%, and 40.36% for IBP. Under the more stringent criteria of 2%/2 mm, passing rates for Patients 1, 2 and 3 were respectively 73.05%, 67.14%, and 86.85% for CBP, and 46.53%, 32.73%, and 36.51% for IBP. The ion chamber measurements were within 3.5%, on average, of those calculated by the TPS and within 2.0%, on average, when compared to the static-point dose measurements for all cases of CBP. Inconsistent breathing patterns between 4D CT simulation and treatment may cause considerable dosimetric differences. Therefore, patient training is important to maintain consistent breathing amplitude during CT scan acquisition and treatment delivery.

Dose verification for Gated Volumetric Modulated Arc Therapy according to Respiratory period (호흡연동 용적변조 회전방사선치료에서 호흡주기에 따른 선량전달 정확성 검증)

  • Jeon, Soo Dong;Bae, Sun Myung;Yoon, In Ha;Kang, Tae Young;Baek, Geum Mun
    • The Journal of Korean Society for Radiation Therapy
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    • v.26 no.1
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    • pp.137-147
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    • 2014
  • Purpose : The purpose of this study is to verify the accuracy of dose delivery according to the patient's breathing cycle in Gated Volumetric Modulated Arc Therapy Materials and Methods : TrueBeam STxTM(Varian Medical System, Palo Alto, CA) was used in this experiment. The Computed tomography(CT) images that were acquired with RANDO Phantom(Alderson Research Laboratories Inc. Stamford. CT, USA), using Computerized treatment planning system(Eclipse 10.0, Varian, USA), were used to create VMAT plans using 10MV FFF with 1500 cGy/fx (case 1, 2, 3) and 220 cGy/fx(case 4, 5, 6) of doserate of 1200 MU/min. The regular respiratory period of 1.5, 2.5, 3.5 and 4.5 sec and the patients respiratory period of 2.2 and 3.5 sec were reproduced with the $QUASAR^{TM}$ Respiratory Motion Phantom(Modus Medical Devices Inc), and it was set up to deliver radiation at the phase mode between the ranges of 30 to 70%. The results were measured at respective respiratory conditions by a 2-Dimensional ion chamber array detector(I'mRT Matrixx, IBA Dosimetry, Germany) and a MultiCube Phantom(IBA Dosimetry, Germany), and the Gamma pass rate(3 mm, 3%) were compared by the IMRT analysis program(OmniPro I'mRT system software Version 1.7b, IBA Dosimetry, Germany) Results : The gamma pass rates of Case 1, 2, 3, 4, 5 and 6 were the results of 100.0, 97.6, 98.1, 96.3, 93.0, 94.8% at a regular respiratory period of 1.5 sec and 98.8, 99.5, 97.5, 99.5, 98.3, 99.6% at 2.5 sec, 99.6, 96.6, 97.5, 99.2, 97.8, 99.1% at 3.5 sec and 99.4, 96.3, 97.2, 99.0, 98.0, 99.3% at 4.5 sec, respectively. When a patient's respiration was reproduced, 97.7, 95.4, 96.2, 98.9, 96.2, 98.4% at average respiratory period of 2.2 sec, and 97.3, 97.5, 96.8, 100.0, 99.3, 99.8% at 3.5 sec, respectively. Conclusion : The experiment showed clinically reliable results of a Gamma pass rate of 95% or more when 2.5 sec or more of a regular breathing period and the patient's breathing were reproduced. While it showed the results of 93.0% and 94.8% at a regular breathing period of 1.5 sec of Case 5 and 6, it could be confirmed that the accurate dose delivery could be possible on the most respiratory conditions because based on the results of 100 patients's respiratory period analysis as no one sustained a respiration of 1.5 sec. But, pretreatment dose verification should be precede because we can't exclude the possibility of error occurrence due to extremely short respiratory period, also a training at the simulation and careful monitoring are necessary for a patient to maintain stable breathing. Consequently, more reliable and accurate treatments can be administered.

Application of the ExacTrac System in Respiratory Gated Radiotherapy for Lung Cancer Patients (폐암 환자의 호흡연동방사선치료를 위한 ExacTrac 시스템 적용)

  • Ko, Seung Young;Lee, Jung Il
    • Journal of the Korean Society of Radiology
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    • v.13 no.3
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    • pp.325-332
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    • 2019
  • This study analyzed the movement of tumors using 4DCT. Appropriate uniform IM were identified using TC, II and CI depending on ITV margins. DVH and NTCP were also compared in each case. Dose analysis on tumors with uniform IM showed that the optimal treatment plan for satisfying all TC, CI, II was evaluated as 2 mm in phase 20 and 3 mm in 40%. That was compared to the dose from the normal tissues of $PTV_{20}$, $PTV_{40}$. In the 20% radiation field, V5, V10, and V20 for the lungs increased 1.49, 1.26, and 0.65%, while 40% increased by 1.9, 2.41 and 1.23%. NTCP had a dose increase of 0.57 to 0.029% from 20% and 40%. There was a dose increase in the spinal cord and heart at uniform IM, but there was no significant difference. These data suggest that the ITV setting of 20%, phase for Respiratory Gated Radiotherapy using Novalis ExacTrac system can be applied with a uniform IM 2 mm and 40% with 3 mm for optimal treatment plan.

성인병 뉴스 제311호

  • The Korea Association of Chronic Disease
    • The Korean Chronic Disease News
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    • no.311
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    • pp.1-18
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    • 2006
  • 경기도 평택시 송탄 보건소 김보섭 소장/만성질환 관리 중추적 단체 위상제고/“앞으로 국민연금 덜 받는다”/건강보험료 환급 사기‘주의’/전공의 보조수당 민간병원 확대/65세이상 60%에 월8만9천원 지급/“의료용 혈액이 부족하다”/남‘암’-여‘순환기’사망확률 높아/수면무호흡증, 남성 발기부전초래/독감백신 국내 생산기반 구축/정부 의약품 가격 정책‘위헌소송’/차별화 된 고품격 보건서비스 제공/보건소 의료기관 서비스 만족도‘1위’/초고령사회 대응, 본격 시동 걸었다/노인의료“의료적 접근 동반돼야”/겨울철 어르신 건강관리 수칙 발표/비영리 의료기관 M&A 근거 마련/병원 서비스산업 주요 육성방안/고령친화 모델지역 기본구상/

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Doppler Radar System for Long Range Detection of Respiration and Heart Rate (원거리에서 측정 가능한 호흡 및 심박 수 측정을 위한 도플러 레이더 시스템)

  • Lee, Jee-Hoon;Kim, Ki-Beom;Park, Seong-Ook
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.25 no.4
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    • pp.418-425
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    • 2014
  • This paper presents a Ku-Band Doppler Radar System to measure respiration and heart rate. It was measured by using simultaneous radar and ECG(Electrocardiogram). Arctangent demodulation without dc offset compensation can be applied to transmitted I/Q(In-phase & Quadrature-phase) signal in order to improve the RMSE(Root Mean Square Error) about 50 %. The power leaked to receiving antenna from the transmitting antenna is always generated because of continuously opening the transceiver of CW(Continuous Wave) Doppler radar. As the output power increase, leakage power has an effect on the SNR(Signal-to-Noise Ratio) of the system. Therefore, in this paper, leakage cancellation technique that adds the signal having the opposite phase of the leakage power to the leakage power was implemented in order to minimize the decline of receiver sensitivity. By applying the leakage cancellation techniques described above, it is possible to measure the heart rate and respiration of the human at a distance of up to 35 m. the heart rate of the measured data at a distance of 35 m accords with the heart rate extracted from the ECG data.

A 2.4 GHz Bio-Radar System with Small Size and Improved Noise Performance Using Single Circular-Polarized Antenna and PLL (하나의 원형 편파 안테나와 PLL을 이용하여 소형이면서도 개선된 잡음 성능을 갖는 2.4 GHz 바이오 레이더 시스템)

  • Jang, Byung-Jun;Park, Jae-Hyung;Yook, Jong-Gwan;Moon, Jun-Ho;Lee, Kyoung-Joung
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.20 no.12
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    • pp.1325-1332
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    • 2009
  • In this paper, we design a 2.4 GHz bio-radar system that can detect human heartbeat and respiration signals with small size and improved noise performance using single circular-polarized antenna and phase-locked loop. The demonstrated bio-radar system consists of single circular-polarized antenna with $90^{\circ}$ hybrid, low-noise amplifier, power amplifier, voltage-controlled oscillator with phase-locked loop circuits, quadrature demodulator and analog circuits. To realize compact size, the printed annular ring stacked microstrip antenna is integrated on the transceiver circuits, so its dimension is just $40\times40mm^2$. Also, to improve signal-to-noise-ratio performance by phase noise due to transmitter leakage signal, the phase-locked loop circuit is used. The measured results show that the heart rate and respiration accuracy was found to be very high for the distance of 50 cm without the additional digital signal processing.

Development of 4D CT Data Generation Program based on CAD Models through the Convergence of Biomedical Engineering (CAD 모델 기반의 4D CT 데이터 제작 의용공학 융합 프로그램 개발)

  • Seo, Jeong Min;Han, Min Cheol;Lee, Hyun Su;Lee, Se Hyung;Kim, Chan Hyeong
    • Journal of the Korea Convergence Society
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    • v.8 no.4
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    • pp.131-137
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    • 2017
  • In the present study, we developed the 4D CT data generation program from CAD-based models. To evaluate the developed program, a CAD-based respiratory motion phantom was designed using CAD software, and converted into 4D CT dataset, which include 10 phases of 3D CTs. The generated 4D CT dataset was evaluated its effectiveness and accuracy through the implementation in radiation therapy planning system (RTPS). Consequently, the results show that the generated 4D CT dataset can be successfully implemented in RTPS, and targets in all phases of 4D CT dataset were moved well according to the user parameters (10 mm) with its stationarily volume (8.8 cc). The developed program, unlike real 4D CT scanner, due to the its ability to make a gold-standard dataset without any artifacts constructed by modality's movements, we believe that this program will be used when the motion effect is important, such as 4D radiation treatment planning and 4D radiation imaging.