• Tuberculosis and Respiratory Diseases
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• v.43 no.4
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• pp.613-622
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• 1996

Constrictive bronchiolitis, one of small airway diseases, is very rare and occupies one of the two arms of bronchiolitis obliterans together with proliferative bronchiolitis. Proliferative bronchiolitis, presenting the prototype with bronchiolitis obliterans with organizing pneumonia(BOOP), can be easily taken into diagnostic consideration in terms of relatively rapid clinical course and radiologic presentation as if atypical pneumonia with interstitial and alveolar infiltrations. Meanwhile constrictive bronchiolitis is not only very Tare but also easily overlooked as chronic obstructive pulmonary diseases such as emphysema, because it usually shows normal chest radiographic finding and obstructive pattern in pulmonary function test. In the aspects of the response to treatment, proliferative bronchiolitis showed dramatic response to the corticosteroid while constrictive bronchiolitis is intractable, which is easily explained on the basis of the pathologic characteristics of cicartrical replacement of bronchiolar walls. The bronchiolitis, both proliferative and constrictive, can be associated with diverse conditions such as inhalational injury, postinfectious process, drug of chemical induced reactions, connective tissue diseases, and organ trasplantation. And there is idiopathic type which has no associated condition. There is one explanation that both types of bronchiolitis lie on the same disease spectrum because the different disease pattern can be evoked from the same etiology. In contrast, another explanation is suggested that both types of bronchiolitis are one of nonspecific tissue reaction rather than a disease specific histologic finding because the various types of causes can provoke the same histologic findings. These dilemma remains for further investigation. With literature investigation, the authors report a case of constrictive bronchiolitis proven by open lung biopsy in 47 year old female who was diagnosed as non-Hodgkin's lymphoma and simultaneously had relatively rapid progression of airflow obstruction and showed negative radiographic finding without the rise factors for the development of chronic obstructive lung disease. We consider it as idiopathic because we could not find any relationship between constrictive bronchiolitis and non-Hodgkin's lymphoma on the literature search and it requires further investigation.

• 한국방재학회:학술대회논문집
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• 2011.02a
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• pp.173-173
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• 2011

최근 기후변화로 인한 기상재해 중 건조와 관련하여 인플루엔자, 호흡기질환 등과 같은 질병과 산불발생빈도의 증가로 인해 건강 및 재산상의 피해가 증가하고 있다. 특히, 한반도의 주택지역은 산림지역과 근접하여 산불 발생시 그 피해와 복구비용이 막대한 것으로 나타났다. 뿐만 아니라 향후 지구온난화가 가속화 될 경우 건조와 관련한 환자와 산불로 인한 피해가 증가할 것으로 예상되므로, 이에 대한 사전방재계획 및 복구계획 등이 필요하다. 이와 같은 건조현상 등의 자연재해에 대한 방재계획이 효과적으로 운영되기 위해서는 방재 정보를 인지하고 실천하는 개인의 적극적인 활용이 필요하다. 특히, 개인의 생활에 영향을 미치는 피해는 정부적인 대책보다 개인이 스스로 인지하여 대비함으로써 감소시킬 수 있기 때문에 재해에 대한 개인의 인지정도는 대책마련에 있어 중요한 요인이 된다. 이에 따라, 본 연구에서는 건조로 인한 질병 및 산불 발생 등 기상재해 증가에 대한 사전방재계획의 효과적인 운영을 위하여 설문조사분석을 통한 일반인의 건조특보 인지도 및 활용도 분석을 실시하였다. 또한, 기후가 변화함에 따라 더운 낮과 밤의 증가로 건조현상뿐만 아니라 폭염의 발생빈도도 증가할 것으로 예상되고 있다. 이와 관련하여 기후변화 적응측면에서 국민들의 건조특보 및 폭염특보와 관련한 정보 습득이 잘 이루어지고 있는지를 파악하고자 한다. 이를 위해, 선행연구에서 대학생의 주된 폭염특보 관련 정보습득경로가 TV와 인터넷인 점을 참고하여, 기상청에서 제공하는 건조특보와 폭염특보 발표일수와 TV, 인터넷의 대중매체를 통한 보도회수를 비교 분석하였다. 본 연구를 통해 대학생집단과, 10대, 20대의 저연령층의 인지도가 상대적으로 낮은 것으로 파악되었으며, 이는 대중 매체를 통한 건조특보와 관련한 정보전달의 부족으로 나타났다. 폭염특보와 관련한 언론보도는 기상전달뿐만 아니라, 폭염의 위험성, 폭염으로 인한 피해상황, 폭염특보제 홍보, 폭염과 관련한 대비책 등 다양한 내용으로 기재되었다. 반면에, 건조특보의 경우에는 대부분이 단순 기상전달로 폭염특보에 비해 보도의 다양성이 결여되어 있었다. 차후 대중매체를 통한 이용자들의 접근성을 증대시키기 위해서 신속하고 정확한 정보전달이 필요하다. 산불 및 화재예방과 관련하여 기상청의 정확한 기상정보 제공과 사전방재계획 수립에 대한 필요성을 직업별, 연령별로 구성된 각 집단의 50%이상이 느끼는 것으로 나타났다. 이에 따라, 기상정보 전달의 핵심인 기상청을 중심으로 온라인/오프라인 상의 기초교육부터 체계적인 사전방재계획 및 안전교육 프로그램 마련이 필요하다.

• Clinical and Experimental Pediatrics
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• v.52 no.10
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• pp.1153-1160
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• 2009

Purpose:To evaluate the risk factors for mortality and prognostic factors in pediatric hemato-oncology patients admitted to the pediatric intensive care unit (PICU). Methods:We retrospectively reviewed the medical records of pediatric hemato-oncology patients admitted at the PICU of the Asan Medical Center between September 2005 and July 2008. Patients admitted at the PICU for perioperative or terminal care were excluded. Results:Total 88 patients were analyzed. Overall ICU mortality rate was 34.1%. Mean age at PICU admission was $7.0{\pm}5.7$ years and mean duration of PICU stay was $18.1{\pm}22.2$ days. Hematologic diseases contributed to 77.3% of all the primary diagnoses, and the primary cause of admission was respiratory failure (39.8%). The factors related to increased mortality were C-reactive protein level (P<0.01), ventilation or dialysis requirement (P<0.01), and hematopoietic stem cell transplantation (P<0.05). In all, 3 scoring systems were investigated [Number of Organ System Failures (OSF number), the Pediatric Risk of Mortality III (PRISM III) score, and the Sequential Organ Failure Assessment (SOFA) score]; higher score correlated with worse outcome (P<0.01). The Oncological Pediatric Risk of Mortality (O-PRISM) scores of the 21 patients who had received hematopoietic stem cell transplantation were higher among the non-survivors, but not statistically significant (P=0.203). Conclusion:The PRISM III and SOFA scores obtained within 24 hours of PICU admission were found to be useful as early mortality predictors. The highest OSF number during the PICU stay was closely related to poor outcome.

• Tuberculosis and Respiratory Diseases
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• v.44 no.1
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• pp.146-153
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• 1997

Background : Chronic cough is commomly defined as a persistent or recurrent cough exceeding 3 week's duration. The prevalence of chroinc cough is reported to range from 14% to 23 % for nonsmoking adults. The post nasal drip syndrome has been determined to be the most common cause of chronic cough, followed by asthma, chronic bronchitis, gastroesophageal reflux and bronchiectasis. Cough can be the only manifestation of asthma. Bronchial provocation tests are useful in diagnosing cough variant asthma. We investigated the clinical or laboratory findings and the incidence of airway hyperresponsiveness and evaluated the etiology in patients with chronic cough. Method : We evaluated 46 patients with chronic cough. Methacholine challenge test were done. Results : The results were as follows : 1) Thirty - five percent(16/46) of the chronic cough patients and 44% of the post nasal drip syndrom(7/16) showed the positive responses to methacholine challenge test 2) The underlying causes of chronic cough were post nasal drip syndrome in 35%, bronchitis in 21.7%, cough-variant asthma in 17.4%, and unknown condition in 25.9%. 3) Airway hyperresponsiveness in chronic cough was not related to respiratory symptom, nasal symptom, post nasal drip, smoking, derangement of ventilatory function, atopy, or sinusitis. Conclusion : Airway hyperresponsivenss in patients with chronic cough increased in frequency when compaired with normal control, allergic rhinitis. Cough-variant asthma account for 17.4% of patients with chronic cough.

• Tuberculosis and Respiratory Diseases
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• v.54 no.4
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• pp.395-402
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• 2003

Background : Patients with chronic obstructive pulmonary disease (COPD) are at increased risk for osteoporosis, which has implications for mobility and even mortality. The goal of this pilot study was to evaluate bone mineral density (BMD) and risk factors for osteoporosis in a limited number of men with COPD. Methods : We checked BMD, $FEV_1$(% of predicted) and investigated risk factors for osteoporosis in 44 male patients with COPD who visited our hospital from January to August 2002. Results : Mean(${\pm}$) age was $69{\pm}9$ yrs, body mass index(BMI) $21{\pm}3kg/m^2$, $FEV_1$ $50{\pm}18%$ of predicted, lumbar spine T-score $-3.0{\pm}1.2$, lumbar spine Z-score $-2.0{\pm}1.2$, and lumbar spine BMD $0.76{\pm}0.13g/cm^2$. Osteoporosis(T-score below -2.5) was present in 27 patients(61.4%) and osteopenia(T-score between -1 and -2.5) in 17(38.6%). None of the patients had normal BMD. There was no relationship between BMD and $FEV_1$(% of predicted). There were significant differences in smoking, alcohol consumption, exercise, cumulative steroid dose, BMI and BMD among the three groups according to $FEV_1$(% of predicted) (group1 : ${\geq}65%$, group2 : 50-64%, group3 : ${\leq}49%$), except age. However, there were no significant differences in these variables between the osteopenia and osteoporosis groups, except BMI. Linear Regression(Stepwise) analysis showed that lumbar BMD was correlated with BMI & exercise. Conclusion : BMD is significantly reduced in men with COPD. There was no relationship between BMD and pulmonary function.

• Korean Journal of Culture and Social Issue
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• v.29 no.3
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• pp.405-427
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• 2023

This study aimed to identify demographic variables(gender, age group, occupation, living arrangement, economic level, respiratory and chronic diseases, previous medical history), COVID-19 variables(COVID-19 prevention behavior, frequent use of media to obtain COVID-19 information), and psychological behavioral variables(depression, anxiety, loneliness, and increased drinking). From February to March 2021, an online survey of adults was conducted, and a total of 1,434 data were used for analysis. 260 out of 1,434 people were confirmed to have suicide ideation, the prevalence of suicide ideation among adults during the COVID-19 was 18.1%. Logistic regression analyses indicated elevated odds of suicidal ideation among individuals in their 20s and 30s, those living alone, exhibiting fewer COVID-19 preventive behaviors, consuming COVID-19 information more frequently through media, and reporting higher levels of loneliness. Furthermore, within the group experiencing depression, anxiety, and increased drinking, greater levels of these factors correlated with higher odds of suicidal ideation. Based on the results, implications and significance of the study were discussed.

• Journal of Life Science
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• v.16 no.1
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• pp.58-63
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• 2006

There was cross-sectional study on investigating the factors related asbestos-related disease on chest radiograph of workers exposed to asbestos in ship repair. According to Occupational Safety & Health Administration asbestos standard, medical surveillance, chest radiologic study, pulmonary function test and medical questionnaire are performed in 118 subjects exposed to asbestos for 10 years or more in ship repair. The sixteen out of 118 subjects $(13.6\%)$ were observed asbestos-related disease finding on chest radiography. Significant factors related to those finding on chest radiography were abnormal pulmonary function test, cough, sputum, past history of respiratory disease, work duration. Workers with Significant factors related asbestos-related disease finding on chest radiography should be managed on a strict program. Further, factors unrelated with asbestos-related disease finding on this study should be evaluated prospectively for medical surveillance program of workers exposed to asbestos.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.9
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• pp.174-185
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• 2018

This study was conducted to explore the levels of Middle East Respiratory Syndrome (MERS)-related knowledge, attitudes and preventive behaviors performance and to identify predictors of MERS-related preventive behaviors performance among clinical practice students in a tertiary hospital. The participants were 480 nursing and medical clinical practice students. Data collection was conducted using self-reported questionnaires in June of 2015 and were analyzed using descriptive statistics, independent t-tests, one-way ANOVA, and hierarchical regression using the SPSSWIN 24.0 program. The MERS-related knowledge (9.56 out of 13 points) was high, attitudes towards MERS, such as severity cognition and prevention about MERS was positive (4.15 out of 5 points), and MERS-related preventive behaviors performance level was moderate (3.02 out of 5 points). Female students, having education experience regarding MERS, taking vaccination for influenza H1N1 infection in the last year, having the intention of taking influenza H1N1 in the current year, having fear of MERS infection, higher knowledge and more positive attitudes about MERS were predictors of better MERS-related preventive behaviors performance. These results show that general characteristics associated with MERS-related preventive behaviors performance should be considered to improve preventive behaviors of clinical practice students. Furthermore, this study highlights the need to develop effective and useful MERS education programs that provide essential knowledge and attitude about MERS that clinical practice students must acquire to promote the MERS-related preventive behaviors performance.

• Tuberculosis and Respiratory Diseases
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• v.39 no.5
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• pp.392-399
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• 1992

Background: Despite dyspnea is a predominant complaint of patients with respiratory disease, the mechanisms contributing to the sensation of breathlessness are poorly understood. Traditionally, physicians have measured objective pulmonary function to assess severity of dyspnea. But it will be also useful to measure subjective dyspnea index because dyspnea probably depends on a complex interplay of mechanical, experimental, emotional and other factors. Method: We measured breathlessness at rest, after Methacholine challenge and then bronchodilator inhalation using a Visual Analogue Scale (VAS) and Borg Scale Dyspnea Index (BSDI) in stable asthmatic patients. Spirometry was performed concomittently. Results: There was no correlation between dyspnea index and FEV1. There was also no correlation between the change in dyspnea index and change in FEV1. The change in dyspnea index after methacholine and bronchodilator was greater in clinically mild asthmatic patients than clinically severe symptomatic group. Conclusion: In asthmatic patients, there was a wide variation in sensory response for any given FEV1, and the change in perception of dyspnea was greater in those with clinically mild symptoms. The measurement of dyspnea index may yield information complementary to that obtained by spirometry.

• Journal of the Korean Society of Food Science and Nutrition
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• v.34 no.7
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• pp.1018-1027
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• 2005

The purpose of this study was to investigate nutrients intake and health-related behaviors in elderly people residing in Gyeongsan-si, Gyeongbuk who have no problem in daily living. Information on general characteristics of the elderly, health-related behaviors and dietary habits were obtained by interview based on questionnare. Dietary nutrients intake data were obtained through the 24 recall method. The subject group of this study was composed of 113 males and 112 females, the average age being $73.1\pm6.06$ years old. In health related factors, $76.9\%$ of subjects exercised regularly. The rates of alcohol drinking and smoking showed to be $38.2\%\;and\;22.2\%$, respectively. There were many elderly with neuralgia, hypertension, and gastrointestinal disease, especially female were worse. Average heights of the subjects were lower than the standard established in the Korean Recommended Dietary Allowances, and average weights were similar to the standards. The mean BMI and WHR were 24.8 (male 23.7, female 25.7) and 0.92 (male 0.92, female 0.89), respectively. Most of the subjects had a regular meal pattern comsuming three meals a day, and many elderly, especially more than $79.5\%$ of female, prepared the meals for themselves. Mean daily energy intakes and RDA percentage of energy intakes of the male and female subjects were estimated as 1426.9kcal $(79.3\%)$ and 1381.3 kcal $(86.3\%)$, respectively. Mean daily intakes of nutrients were estimatied as 48.1g for protein, 411.3mg for calcium, 8.05mg for iron, 541.8 R.E. for vitamin A, 0.84mg for vitamin $B_1$, and 0.79mg for vitamin $B_2$. Most nutrients except protein, clacium, iron and vitamin $B_2$ were consumed over $75\%$ of the RDA. Female elderly showed significant lower intakes (p<0.05) for most of the nutrients except calcium, phosphorus and vitamin ethan the elderly male.