• 대한세포병리학회:학술대회논문집
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• 1992.11a
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• pp.18.2-18.2
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• 1992

• Journal of Chest Surgery
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• v.34 no.2
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• pp.180-183
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• 2001

Oncocytic carcinoid는 매우 드문 종양으로 단지 몇 례만이 문헌상 보고되고 있다. 본 저자들은 좌폐 상엽에 발생한 oncocytic carcinoid 1례를 치험하였는데 환자는 56세된 여자환로 특이한 증상은 없었다. 흉부 전산화 단층촬영상 좌폐상엽에 3$\times$3.5 cm 크기의 동종의 종괴를 보이고 있었다. 수술전 검사후 외과적절제술을 시행하였는데 육안적소견상 4$\times$3cm 크기의 경계가 명확한 황갈색의 종괴였으며, 병리조직학적 검사상 괴립성 호산성 세포질이 풍부한 양상을 보였으며 면역조직학적 검사에서는 cytokeratin에 양성반응을 보였으며 EMA와 chromograin에 국소적인 양성반응을 보여, 폐에 발생한 oncocytic carcinoid로 진단하였다. 수술후 환자의 상태는 양호하였으며, 현재 외래추적관찰중이다.

• Journal of Life Science
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• v.11 no.5
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• pp.489-495
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• 2001

The effect of ozone-water treatment on the morphological change of endosperm cells and the activity of acid phosphatase during Glycine max germination was investigated with electron microscope. Acid phosphatase showed the activity in the cell organelles of germinating endosperm of seed. it's activity occurrs in 12 hrs cultivation after 0.5 ppm ozone-water treatment. As the differentiation of endosperm, reaction products of the acid phosphatase appear to be accumulated invacuole after treatment of ozone-water. This result confirm that acid phosphatase is inveolved in the decomposition and translation of the intracellular storage materials. The characteristics of grganelle in the endosperm cell during germination were discussed.

• The Korean Journal of Nuclear Medicine
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• v.33 no.2
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• pp.120-130
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• 1999

Purpose: This study was performed to evaluate the diagnostic usefulness of double-phase Tc-99m MIBI parathyroid scintigraphy with single photon emission computed tomography (SPECT) in patients with hyper-parathyroidism. We also evaluated the relationship between Tc-99m MIBI uptake and oxyphil cell contents in parathyroid glands. Materials and Methods: The subjects were 28 parathyroid glands of 10 patients who underwent Tc-99m MIBI parathyroid scintigraphy and parathyroidectomy for clinically suspected hyper-parathyroidism. Early and delayed pinhole images were obtained at 15 minutes and 2 hours after injection of Tc-99m MIBI, and SPECT images were followed. The weight and oxyphil cell contents of parathyroid tissue were obtained from pathologic specimen, and the scintigraphic findings were compared with histopathology. Results: In surgical histopathology, 6 parathyroid adenomas and 9 parathyroid hyperplasias were confirmed. The sensitivity, specificity, and positive predictive value of early and delayed images were 46.7% (7/15), 76.9% (10/13), 70% (7/10) and 66.7% (10/15), 92.3% (12/13), 90.9% (10/11), respectively. SPECT image detected an additional small hyperplasia.. The sensitivity, specificity, and positive predictive value of combined interpretation of early and delayed images with SPECT were 73.3% (11/15), 100% (13/13), 100% (11/11). The sensitivity was 100% (6/6) for adenoma, whereas that was 55.5% (5/9) for hyperplasia. Both adenomas and hyperplasias showed significantly increased oxyphil cell contents compared with normal parathyroid glands (p<0.0001), but the oxyphil cell content and weight were not significantly different between adenomas and hyperplasias. Conclusion: Double-phase Tc-99m MIBI parathyroid scintigraphy with SPECT is useful for lesion localization in patients with hyperparathyroidism. Although both adenoma and hyperplasia have increased oxyphil cell content, the sensitivity is high in adenoma, but low in hyperplasia.

• Journal of Marine Life Science
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• v.7 no.1
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• pp.55-59
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• 2022

This study was conducted to provide basic information on the sexual mature and reproductive biology of Trichiurus lepturus. During the oogenesis, size of oocyte and nucleus showed the increase tendency but size ratio of nucleolus to nucleus was decreased. In the result of H-E stain, the stainability of the cytoplasm was changed from basophilic to eosinophilic. The egg diameter of initial vitellogenic oocyte was about 63.2 (±12.7) ㎛. In the cytoplasmic cortex, eosinophilic yolk nucleus was observed. The size of mature oocyte was 216.6 (±24.7) ㎛ and GVBD (germinal vesicle breakdown) was observed. The size of ripe oocyte was 317.9 (±80.9) ㎛ and the thickness of zona radiata was 4.2 (±1.7) ㎛. The oocyte developmental type is considered to belong to the group synchronous type. The accumulation of yolk in the oocyte, like most teleost, is thought to be of two types: exogenous and endogenous accumulation.

• Applied Microscopy
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• v.33 no.1
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• pp.41-48
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• 2003

The hemopoiesis in human fetal spleen was studied with transmission electron microscope. There were undifferentiated proerythroblast, basophilic erythroblast, polychromatophilic erythroblast, and acidophilic erythroblast. Besides, enucleated nuclei and mitoses were present. Groups of erythroblastic cells were surrounded by certain cell. The structure was identical to erythropoietic island found in fetal liver. So, erythropoisis in spleen was developing in a pattern similar to fetal liver. Megakaryobalst were found in spleen, but there was no mature cells, cells in mitosis nor platelet formation. It was not clear whether megakaryoblast in circulation was trapped in spleen or participated in megakaryopoiesis. In summary, erythropoiesis took place in fetal spleen in a pattern similar to fetal liver and bone marrow. But it was not certain whether megakaryopoiesis took place in fetal spleen.

• Korean Journal of Ichthyology
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• v.28 no.1
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• pp.19-27
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• 2016

The RLG (relative length of gut) is 1.52 (n=12) in the sablefish, Anoplopoma fimbria. The digestive tract has five or six pyloric caeca in the posterior region of stomach. Morphology of mucosal fold is unbranched type in the esophagus and stomach, but branched type in the intestine. The histological structure of digestive tract can be divided into mucosal layer, submucosal layer, muscular layer and serous membrane in the cross section. In the esophagus, mucosal epithelial layer is a simple, and consists of ciliated columnar epithelia and mucous cells. In the stomach, gastric gland of mucosal epithelial layer is a tubular, and is composed of chief cell, parietal cell and mucin secreting cell, which is columnar and contained secretory granules of red and blue colors in the AB-PAS (pH 2.5) reaction. In the intestine, mucosal epithelial layer is a simple, and consists of ciliated columnar epithelia and goblet cells. The submucosal layer is composed mainly of collagen fibers, and well developed in the esophagus. And the muscular layer of digestive tract is divided into longitudinal and circular muscle layer, and well developed in the stomach. The liver is composed of numerous lobular structure and bile canaliculi. Stainability of hepatocyte cytoplasm was eosinophilic, and nucleus and nucleolus showed basophilic in the H-E stain. The pancreatic tissue was scattered in the fatty tissue near the digestive tract, and acinar gland consisting of numerous exocrine cells. And cytoplasmic stainability of exocrine cell was basophilic, and contained numerous zymogen granules of eosinophilic in the H-E stain.

• The Korean Journal of Cytopathology
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• v.8 no.1
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• pp.52-56
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• 1997

Oxyphilic (Hurthle) cells have abundant eosinophilic granular cytoplasms and occur in both benign and malignant neoplasms of the thyroid gland. Most published studies described mainly oxyphilic tumors of follicular type, and reports on oxyphilic papillary thyroid carcinomas are rare. The oxyphilic variant of papillary carcinoma differs from the classic papillary carcinoma in its more aggressive biological behavior. We report a case of oxyphilic papillary carcinoma exhibiting exclusively oxyphilic cells in a follicular pattern without papillary structures. The pattern of papillary carcinoma was confirmed by fine needle aspiration material and lymph nodal metastasis, both of which revealed typicaled papillary structures with characteristic nuclear features, psammoma bodies, and oxyphilic cytoplasm.

• Korean Journal of Head & Neck Oncology
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• v.25 no.2
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• pp.146-149
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• 2009

외이도의 종양은 드물며, 귀지샘에서 기원한 종양은 더욱 흔하지 않다. 저자들은 이루를 동반한 2예의 귀지샘종을 보고하고자 한다. 현미경적으로, 2예 모두 중층 혹은 단층으로 둘러싸인 세관 혹은 샘으로 이루어진 경계가 좋은 종양이었다. 종양세포는 과립성의 풍부한 호산성 세포질을 가졌고, 세포질의 관내 돌출이 관찰되어 아포크린화생을 보였다. 완전 절제후 재발은 관찰되지 않았다. 귀지샘종은 경계가 좋은 양성종양이며, 광범위 절제 치료하지만, 높은 재발율을 보인다. 여기에서 외이도에서 발생한 귀지샘종의 임상적 소견과 함께 병리 소견에 대해 기술하였다.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.17 no.2
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• pp.143-145
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• 2006

Oncocytic hyperplasia is uncommon in the practice of otolaryngology. Oncocytic hyperplasia usually arises in the major salivary gland, especially parotid gland. We have recently experienced a case of oncocytic hyperplasia arising in the larynx of 58 year old female patient. The mass was removed under the general anesthesia using laryngeal micro-surgery and confirmed as oncocytic hyperplasia of larynx on histopathological examination.