• Food Science and Preservation
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• v.15 no.4
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• pp.606-611
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• 2008

Myungran Jeotkal, Korean fermented seafood, and its ingredients(hot red pepper powder, ginger, garlic, and seasoning mix) were irradiated with 0, 0.5, 1.0, 2.0, and 5.0 kGy of gamma rays and stored at 4C for 4 weeks to determine changes in microbiological and sensory characteristics. Water activities of Myungran Jeotkal, hot red pepper powder, ginger, garlic, and seasoning mix were 0.89 0.56, 0.98, 0.99, and 0.07, respectively. Myungran Jeotkal was observed to be initially contaminated. Total aerobic bacteria, yeast and mold, and coliform levels were 6.7, 4.3, and 3.6 log CFU/g, respectively. Irradiation at 2 kGy afforded approximately a 4 log reduction in total aerobic bacteria, and a 3 log drop in both yeast and mold levels and coliform bacteria(P<0.05). No viable microbial cells were detected in Myungran Jeotkal after 5 kGy of irradiation(at a detection limit of 101 CFU/g). The total aerobic bacterial level in red pepper powder was 6.3 log CFU/g and this component, of the tested ingredients, contributed most to the microbial contamination of Myungran Jeotkal. The initial count of total aerobic bacteria, 6.3 log CFU/g, was significantly reduced to 4.5 log CFU/g after irradiation(P<0.05). Sensory evaluation showed that gamma irradiation of up to 5.0 kGy did not adversely affect overall acceptability of Myungran Jeotkal or its ingredients during cold storage. Therefore, gamma irradiationwas effective to extend the shelf-life of Myungran Jeotkal.

• Food Science and Preservation
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• v.24 no.5
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• pp.608-614
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• 2017

This study was conducted to investigate the effect of chlorine dioxide fumigation as a substitute for sulfur fumigation which has been used as a method to prevent the quality change of persimmon during storage and distribution process. Dried persimmons were treated with chlorine dioxide gas concentration (0, 15 30, and 45 ppm) and time (0, 15, 30, and 45 min) and microbiological changes, texture properties and color of the treated samples were investigated during storage at room temperature. Total aerobic bacteria, yeast and mold numbers after chlorine dioxide gas fumigation were decreased when compared with the control group. The inhibitory effects of total aerobic bacteria, yeast, and mold were observed during storage. The texture properties and color value of dried persimmons were not affected by chlorine dioxide gas fumigation concentration and time. There was no difference in quality between chlorine dioxide gas fumigation treatment group and control group. These results suggested that chlorine dioxide gas fumigation treatment can be utilized as a processing technique to secure microbiological storage stability of dried persimmons.

• Journal of Korean Society of Environmental Engineers
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• v.28 no.3
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• pp.276-285
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• 2006

When polluted stream water was treated with biological aerated filter(BAF) in pilot plant, all operation with 90, 60, 45 and 30 min of EBCT at fixed $0.1m^3air/m^2min$ of aeration showed 80% or higher treatment efficiency of particle materials(SS, turbidity and Chl.-a) and 85% or higher efficiency of ammonia nitrogen removal. It was thought that, in case of BOD, biological stability may sufficiently be assured with BAF because grade III or IV inflow water was changed to grade I for outflow water. In case of $COD_{Mn}$, about 60% of removal efficiency was found. When the mechanism of the result was investigated, about 30% of COD materials was produced by algae clogged in the reactor. There was almost no biological decomposition because specific substrate utilization rate of algogenic organic materials were $0.0245mg{\cdot}COD_{Mn}/mg{\cdot}VSS{\cdot}day$, thus partial backwashing(washing the media in 1 m upper of the reactor once a day) was required. It is thought that elevation of removal rate about 10% of $COD_{Mn}$ and 5.5% of $BOD_5$ could be obtained with partial backwashing resulting in assurance of biologically more stable raw water and that saving backwashing water may be significant.

• Korean Journal of Food Science and Technology
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• v.36 no.2
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• pp.355-360
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• 2004

Residual contamination levels of natural microflora in strawberries were evaluated. Approximate counts of total aerobic mesophilic bacteria, total coliforms, and lactic acid bacteria were 8, 2, and 3 log CFU/g, respectively, whereas those of Escherichia coli and yeasts/molds were under the detection limit (<10 cells/g). Growth inhibition degrees of total aerobic mesophilic bacteria, total coliforms, and lactic acid bacteria were also evaluated based on three hurdles of preservative, storage temperature, and pH of strawberry paste prepared as model system. Strawberry paste was stored at low ($4^{\circ}C$), room ($20^{\circ}C$), and high ($37^{\circ}C$) temperatures. Potassium sorbate was added as a preservative up to 0.1%. Acidity of strawberry paste was adjusted to pH 4 or 7. During 7-day storage, inhibitory effects of the hurdles against bacterial groups were: storage temperature > pH of strawberry paste > addition of potassium sorbate. Combination of three hurdles most effectively inhibited growth of residual microflora.

• Korean Journal of Food Science and Technology
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• v.52 no.2
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• pp.177-182
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• 2020

This study evaluated the effect of steam heating, gamma irradiation, and ultraviolet (UV) irradiation on microorganism reduction in order to determine an effective sterilization method for red pepper powder. The effect of each treatment on the reduction of thermoduric bacteria and total aerobic bacteria in red pepper powder were as follows: 10 kGy gamma irradiation, reduction of 4 log and 6 log CFU/g, respectively; 12 mW/㎠ UV irradiation (264 nm UV-C), reduction of less than 1 log CFU/g; steam heating at 120℃ for 40 s, reduction of approximately 2 log CFU/g. High-temperature short-time processing at 110℃ for 30 s reduced the total bacterial count in Gochujang solution from 5.70 log CFU/g to 2.26 log CFU/g; at 121℃, the solution was commercially sterile. Steam heating resulted in 1, 2, and 4 log microbial inactivation in garlic, onion, and pepper powder, respectively. Steam sterilization, which consumers prefer over other methods, may be an effective method for reducing microorganisms in spice powders, including those in red pepper powder.

• Korean Journal of Food Science and Technology
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• v.32 no.2
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• pp.356-362
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• 2000

Yakju(rice wine) was sterilized with high-voltage square-wave pulses of $1\;{\mu}s$ duration at various electric field strengths and frequencies on a serial multiple electrode pulsed electric field(PEF) treatment system consisted of 7 electrodes connected in series. The initial microbial counts of Yakju were $1.88{\times}10^3{\sim}2.13{\times}10^4$ CFU/mL for total aerobes, $1.55{\times}10^3{\sim}2.85{\times}10^4$ CFU/mL for lactic acid bacteria and $1.72{\times}10^3{\sim}2.39{\times}10^4$ CFU/mL for yeasts. The sterilization of microorganisms in Yakju was a first order reaction and the sterilization effect increased as the field strength and the frequency increased. The $D_{Hz}-value$ and the $D_{PEF}-value$ decreased with the electric field strength. Yeast showed lower $D_{PEF}-value$ than bacteria. Lactic acid bacteria showed lower $D_{PEF}-value$ than general aerobic bacteria under the electric field strength below 30 kV/cm, but higher ones under that above 40 kV/cm. The $Z_{PEF}-value$ of general aerobic bacteria, lactic acid bacteria and yeast in Yakju were 39.4, 49.3 and 47.6 kV/cm, respectively. The PEF sterilization resulted in less changes in color and sensory properties than heat sterilization, and the PEF treated Yakju showed superior quality to the heat treated one. The commercial sterilization of Yakju was accomplished with 2-cycle treatment on the tested serial PEF treatment system.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.4
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• pp.56-66
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• 2021

In this study, a waste heat recovery system was devised and the performances of components incorporated to recover the heat generated during the processing of aerobic liquid-composting in a livestock manure treatment facility were analyzed. In addition, the availability of recovered heat was confirmed. The heat generated by liquid fermentation in the livestock manure treatment facility was also checked. Experimental temperatures were set at 35, 40, and 45 ℃ based on considerations of the uniformity of aerobic liquid-composting fermentation tank temperature and its operating range (34.5 ~ 43.9 ℃). Recovered heat energies from the combined heat exchanger, which consisted of PE and STS pipes, were 53.5, 65.6, 74.4 MJ/h, The heat pump of capacity 5 RT was heated at 95.6, 96.1, 98.9 MJ/h and the heating COPs of the pump were 4.53, 4.62, and 4.65, respectively. The maximum hot water production capacity of the heat exchanger assuming a fermentation tank temperature of 45 ℃ confirmed an energy supply of 56 360 kcal/day. The heating capacity of the FCU linked to the heat storage tank was 20.8 MJ/h, and the energy utilization efficiency was 96.1%. When livestock manure was dried using the FCU, it was confirmed that the initial function rate was reduced by 50.5 to 45.8 % after drying.

• Journal of Life Science
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• v.28 no.12
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• pp.1469-1476
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• 2018

Occurrence of the Warburg effect in solid tumors causes resistance to cancer chemotherapy, and targeting energy metabolisms such as aerobic glycolysis is a potential strategy for alternative treatment. Dichloroacetate (DCA), an inhibitor of pyruvate dehydrogenase kinase (PDK), shifts glucose metabolism from aerobic glycolysis to oxidative phosphorylation (OxPhos) in many cancers. In this study, we investigated the anticancer effect of DCA on a human anaplastic thyroid cancer (ATC) cell line, 8505C. We found that DCA selectively inhibits cell proliferation of the 8505C line but not of a normal thyroid line. In 8505C, the cell cycle was arrested at the G1/S phase with DCA treatment as a result of decreased antiapoptotic proteins such as $HIF1{\alpha}$, PDK1, and Bcl-2 and increased proapoptotic proteins such as Bax and p21. DCA treatment enhanced the production of reactive oxygen species which consequently induced cell cycle arrest and apoptosis. Interestingly, DCA treatment not only reduced lactate production but also increased the expression of sodium-iodine symporter, indicating that it restores the OxPhos of glucose metabolism and the iodine metabolism of the ATC. Taken together, our findings suggest that PDK inhibitors such as DCA could be useful anticancer drugs for the treatment of ATC and may also be helpful in combination with chemotherapy and radiotherapy.

• Korean Journal of Mineralogy and Petrology
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• v.33 no.4
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• pp.391-405
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• 2020

Leaching chracteristics of Andong-dam sediment was conducted for heavy metal and nutrients. Five mixed sediment samples were prepared and leaching was conducted under aerobic and anaerobic condition for 60 days. Cd, Cu, Pb, Cr, Zn, Hg, As, Fe, Mn, phosphorus, and nitrogen were analyzed at each sampling time. The leaching rate of phosphorus was higher in anaerobic condition comparing with that of under aerobic condition. Some samples showed higher than the water-quality level IV. In case of As and Cd which showed highest contamination level in the sediment, leached concentration were 0.028 mg/L and 0.003 mg/L in maximum, respectively. The leached concentration is below than the lake water quality standard of Korea. Other heavy metals including Cu, Pb, and Cr also showed similar trend. Five step sequential extraction showed that easily extractable 1-2 step portion such as ion-exchangeable and adsorbed one was less than 10% and the most of the portion was residual. For As and Cd, the residual portion were 80% and 95% respectively indicating the risk by the heavy metal leaching into the lake for a short period was not high in comparing with the contamination levels.

• The Magazine of the Society of Air-Conditioning and Refrigerating Engineers of Korea
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• v.31 no.7
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• pp.53-64
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• 2002

$CO_2$ 20세기 초 천연 냉매 $CO_2$는 광범위하게 사용되었지만 프레온계 냉매의 출현으로 1940년경부터 $CO_2$냉매는 사용이 제한되었다. 그러나 반 세기 동안 사라졌던 $CO_2$냉매는 1980년 후반에 노르웨이 과학 기술대학 (NTNU)과 북구 최대 민간연구소 (SINTEF)의 Lorentzen 교수에 의해 $CO_2$천연 냉매 사용을 재고하게 되었다. 프레온계 냉매의 환경적 논쟁이 쟁점이 되면서 천연 냉매 사용을 재고하게 되었다. 특히 비가연성과 비유독성으로 인한 $CO_2$냉매가 주목을 받고 있다. 초월임계 사이클레서의 고압 제어에 대한 새로운 개념은 Lorentzen 교수와 동료 연구원에 의해서 특허로 제안되었다. 이에 대한 상업적 권리를 Norsk Hydro사는 1990년에 얻었고,1990년대 초반에 NTNU/SINTEF의 공동 연구개발 프로그램을 통해 기술 경쟁력과 실현 가능성이 검증되었다. 현재 연구소에서는 최초로 초월임계 $CO_2$사이클을 이용한 상업용 온수 열펌프 시스템, 2003년 시작할 연료전지 전기 자동차에 대한 연구를 수행하고 있다. NTNU/SINTEF에서 개발된 $CO_2$기술은 Hydro-SINTEF 공동 벤처 기업인 Shecco기술회사를 통해 제조업자에게 허가된다. 본 고에서는 NTNU/SINTEF에서 수행하였거나 수 중인 과제들을 중심으로 유럽의 $CO_2$시스템의 결과와 주요 개발 범위를 정리하였으며, 특히 작동유체로서의 $CO_2$냉매의 특징을 간단히 설명하고, 온 수 열 펌프, 자동차용 공조기 및 열 펌프, 상업 냉동기 등이 기술되었다. 그 외 압축기 위주의 요소기술 개발에 관한 내용도 기술되었고, 차세대 기술 경향과 전망에 대해서도 제시되었다. 제시되었다.성균 350$\times$$10^4$ CFU균, 방선균 434$\times$$10^4$ CFU균, 진균 676$\times$$10^4$ CFU균으로 진균의 개체수가 비교적 높게 나타났으며, 비산불지역에서는 호기성균 328$\times$$10^4$ CFU균, 방선균 319$\times$$10^4$ CFU균, 진균 461$\times$$10^4$ CFU균으로 진균의 개체수가 높게 나타났다. 토양미생물은 호기성균, 방선균, 진균 모두 비산불지역 보다 산불지역에서 많이 나타났다. 본 조사지역에서 호기성균은 활엽수림보다 침엽수림에서 많게 나타났으며, 방선균과 진균은 침엽수림보다 활엽수림에서 많이 나타났다.효과와 이를 이용한 자기냉동의 방법 그리고 최근에 이루어진 새로운 진전에 대해 소개하고 공기조화 및 냉동분야에의 적용 가능성을 전망해 보고자 한다.및 도입 등 선주들에게 다양한 선박건조자금을 제공하여 내수기반 확충에도 노력해야 할 것 이다.있었다., 인삼이 성장될 때 부분적인 영양상태의 불충분이나 기후 등에 따른 영향을 받을 수 있기 때문에 앞으로 이에 대한 많은 연구가 이루어져야할 것으로 판단된다.태에도 불구하고 [-wh]의미의 겹의문사는 병렬적 관계의 합성어가 아니라 내부구조를 지니지 않은 단순한 단어(minimal $X^{0}$ elements)로 가정한다. 즉, [+wh] 의미의 겹의문사는 동일한 구성요 소를 지닌 병렬적 합성어([$[W1]_{XO-}$ $[W1]_{XO}$ ]$_{XO}$)로 그리고 [-wh] 의미의 겹의문사는 중복된 발은을 지닌 한 단어로 ([W]$_{XO}$ )