• Proceedings of the Korean Society of Applied Pharmacology
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• 1992.05a
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• pp.59-59
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• 1992

간헐적 혈액투석 또는 지속적 복막투석 요법을 받고 있는 만성 신부전 환자에서 carumonam의 약동학적 변화를 분석하여 이 환자들에서 적절한 투여용법을 고안하고, 이들 특수 질환군에서의 임상시험모형을 도굴하고자 하였다. 혈액투석환자는 carumonam 1g을 20분간 지속 정주 후 약물의 분포기 종료가 예상되는 시간에 혈액투석을 4-5시간 시행하였으며, 혈액, 투석액, 뇨를 경시적으로 채취하였다. 지속적 복막투석 환자군에 있어서는 1일 3회(6, 6, 12시간) 복막 투석을 시행하는 환자를 대상으로 carumonam 1g을 정주하고 24시간동안 혈액 및 투석액, 뇨를 경시적으로 채취하였다. 혈액, 투석액 및 뇨중 carumonam의 농도는 HPLC방법으로 측정하였으며, 경시적인 혈장 carumonam 농도변화 및 투석에 따른 약물의 제거를 혈액 투석환자는 2 compartmental model, 복막투석환자에서는 bidirectional 2 compartmental model에 의해 그 약동학적 성상을 분석하였다.

• Journal of Digital Convergence
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• v.13 no.7
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• pp.269-282
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• 2015

This study is to define the hemodiafiltration treatment compliance indicators and discriminate standards for hemodiafiltration patients and development of hemodiafiltration treatment compliance measurement-convergent form. Date was collected from 300 on-line hemodiafiltration patients. To verify the hemodiafiltration treatment compliance indicators and discriminate standards, used construct validity and content validity by clinical professional group. Discriminant ability of 3 indicators-interdialysis weight gain rate(IWGR), serum phosphate level, rate of self change of total hemodiafiltration treatment time(SCR-HEFTT)- is 95.6%(wilks ramda=.256, p=.002). And hemodiafiltration treatment compliance measurement-convergent form has 91.7% discriminant accuracy. Hemodiafiltration treatment compliance is important that nurses can aware pre-stage of complication and give appropriate nursing intervention. Also this measurement can be used for foundation data of the nursing intervention development that prevent dialysis patient's complication.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.04a
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• pp.333-333
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• 1994

목적 : 만성신부전환자에서 carumonam의 약동학적 특성을 검토하고, 동시에 투석에 의한 carumonam의 제거 양상을 분석하여 이들 환자에서 carumonam의 적절한 투여용량 및 용법을 고안하고자 하였다. 방법 : 혈액투석(HD) 또는 지속성 복막투석(CAPD)을 받고 있는 14명의 말기 신부전중 환자를 대상으로 하였다. HD환자에서는 carumonam 1 g을 20분간 지속정주하고 4시간 이후 혈액투석을 4 또는 5 시간 시행하였으며 투약 후 36시간까지 경시적으로 혈액 및 투석액을 채취하여 체액내 약물 농도를 측정하였다. CAPD환자는 1일 3회 (6.6, 12 시간) 투석액을 교환하는 환자를 대상으로 하였고 투석직후 carumonam 1g을 지속정주하고, 투약후 36시간 후까지 경시적으로 혈액 및 투석액을 채취하여 CAPD 환자에서 carumonam의 약동학적 특성을 검토하였다. 체내 동태는 HD의 경우 dialyser를 포함하는 2-compartmental model에 의한 분석을 시행하였고, CAPD를 시행받는 환자의 경우에는 체액과 투석액사이에 bidirectional clearance 개념을 도입한 모델을 이용하여 분석하였다.

• Journal of Digital Convergence
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• v.18 no.11
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• pp.433-441
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• 2020

The specific purpose was to determine the effect of walking on the body composition and hematological index of hemodialysis patients in order to confirm the relationship between activity and health level of hemodialysis patients. The research method is a cross-sectional descriptive survey conducted in hemodialysis patients.The subjects were 66 hemodialysis patients undergoing hemodialysis treatment in B city. As a result of the study, walking was decreased in hemodialysis patients, and there was a difference in hematological index according to walking, but there was no difference in body composition. As body weight increased, skeletal mass, body fat mass, body mass index, abdominal fat percentage, basal metabolism, and protein increased, but total cholesterol and high-density cholesterol decreased. This study proposes to expand the number of subjects of hemodialysis patients to investigate by adding nutritional intake in addition to walking, body composition and hematological index.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.4
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• pp.265-275
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• 2018

This study is a qualitative investigation that used Colaizzi's (1978) phenomenological method to evaluate the meaning and nature of the experience of dialysis of eight long-term (>30 years) hemodialysis patients with chronic renal failure. Data were collected from February 27, 2017 to May 30, 2017 by in-depth interviews. Respondents were then divided into three categories, 'entirely different life', 'getting back up again' and 'focusing on survival' with nine theme clusters and 22 themes. In general, patients initially experienced an entirely different life and overcame a difficult situation when beginning dialysis, then came to know methods for self-care, shared the experience of dialysis, and focused on survival while receiving dialysis over the long-term. Development of variety of education methods depending on long-term experience of dialysis and nursing care intervention to enable chronic patients to adapt to dialysis and continue their own self-management is necessary.

• The Journal of the Korea Contents Association
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• v.17 no.8
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• pp.631-643
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• 2017

The purpose of this study is to examine factors affecting the life satisfaction of patients with hemodialysis in order to improve the quality of life for patients with hemodialysis. The subjects of this study are 168 patients who have undergone hemodialysis treatment in the hemodialysis rooms in D-city and C-providence. The data are collected between August 20th to September 5th, 2015. By using SAS 9.3 statistics program for data analysis, frequency, ${\chi}^2$-test, variance analysis and multiple regression analysis are conducted. Based on the analysis, it is found that family support(t=5.33, p<.001) and self-efficacy(t=3.52, p<.001) are statistically significant to the quality of life for male patients. Family support(t=2.58, p<.012) and adherence to self-care(t=4.08, p<.001) are statistically significant to the quality of life for female patients. With the study results, it suggests that nurses can help improve the affective and psychological stability of patients with hemodialysis by recognizing the factors affecting the life satisfaction of patients with hemodialysis by gender, developing and utilizing a nursing intervention.

• Journal of Industrial Convergence
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• v.22 no.2
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• pp.127-134
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• 2024

This study was attempted to understand the phenomenon in depth by exploring the food craving of hemodialysis patients experienced during hemodialysis. Participants selected seven adult patients diagnosed with end-stage renal failure and receiving hemodialysis treatment from medical institutions. he collected data were analyzed using a phenomenological analysis method. As a result of the analysis the food craving of hemodialysis patients was derived into two categories included craving experience in the cognitive domain craving experience in the emotional domain and five themes: 'Looking for foods that are water and watery as a result of thirst','Food thoughts come to mind all day as a result of a limited diet', 'Always hungry', 'Faced with appetizing situations every hour', 'experiencing negative emotions due to failure to control meals'. The results of this study which sheds light on food craving from the perspective of hemodialysis patients should improve the understanding of hemodialysis patients appetite control water restrictions and dietary compliance and allow them to understand the food craving attributes of hemodialysis patients and provide customized education optimized for that extent when applying dietary education and nursing interventions suitable for them.

• Journal of Digital Convergence
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• v.16 no.7
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• pp.277-288
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• 2018

This study was to investigate the level of knowledge and adherence to EBP guidelines for hemodialysis among nurses in dialysis units. Self-administered questionnaire was used that data were collected. The sample consisted of 173 nurses who worked in hemodialysis units located in three different district areas in Korea. Using SPSS/WIN 20.0, t-test, ANOVA and Scheff's analysis were performed. About 98.8% of nurses in dialysis units had received education mostly from dialysis conferences or symposium. The knowledge score for EBP was 15.77 (out of 23) on average. Subjects with more than 8 years of work experience, master degree and those working in tertiary hospital showed significantly higher scores. Despite that there are internationally acknowledge evidence based guidelines for hemodialysis, the actual adherence to guidelines varies by experience, education level and types of hospital. The findings of this study can be baseline data for further research into development of strategies to enhance knowledge of hemodialysis nurses and utilization of EBP guidelines.

• 한국노년학
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• v.30 no.1
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• pp.179-194
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• 2010

The purpose of this study examines the elderly hemodialysis patients' Health-related quality in life(HRQL) and investigates the relationship between HRQL and transition of health condition. The subject were 443 elderly hemodialysis patients(over 65 years old) in Seoul and Gyeonggi province. The Health-related quality of life scale was used in this research, in which were analysed a wide range of statistical descriptive analysis, Pearson's correlation, reliability analysis, multiple regression and the Scheffe test. The results were as follows. The HRQL were statiscally significant difference by Gender, Educational level, Live with spouse, Best supporter, and Number of Disease. Also the factor related to transition of health condition was Number of Disease. The transition of health condition accounted for 13.9% of variance in HRQL and Number of Disease accounted for an additional 7.4% of HRQL. The factors, which influenced finally on the HRQL in the elderly hemodialysis patients, were transition of health condition and number of disease. In conclusion adequate hemodialysis treatment and social services should be provided in accordance with the factors affecting HRQL in order to improve the HRQL for elderly hemodialysis patients.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.35 no.7B
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• pp.1066-1072
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• 2010

Kidney diseases rates in modern Korean society, which is entering an aging society, are growing. These diseases diagnosed at early stage can be cured with the drug or dietary treatment. If, however, at worsening stage, kidney dialysis or transplant is needed. In this context, we analyzed the relationship between kidney and voice by measuring and analyzing the changing rate of the vocal chord and intensity according to hemodialysis. For this, we collected voice samples before and after hemodialysis, and compared and analyzed them through application of vocal analytical element. Namely, based on oriental medical diagnosis theory that voice is quieted down when kidney is abnormal, we collected voice samples before and after hemodialysis, and applied trembling and intensity analysis of vocal chord.