• Proceedings of the KOR-BRONCHOESO Conference
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• 1987.05a
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• pp.11.2-11
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• 1987

1987년 2월 1일 부터 1987년 3월28일까지 본 병원 인공신장실에서 혈액투석요법을 받고 있는 만성 신부전증 환자 20례 (남자 15례, 여자 5례)를 대상으로 2회의 청력검사를 시행하여 다음과 같은 결과를 얻었다. 1) 만성 신부전증으로 혈액투석요법을 받고 있는 환자 20례 중 7례 (35%)에서 청력손실을 보였다. 2) 연령분포상 20대에서는 2명중 청력손실을 보인 예는 없었으며, 30대는 7명중 1명, 40대는 5명중 4명, 60대는 1명중 1명에서 청력손실을 보였으며 7례 전례가 남자였다. 3) 청력손실의 양상은 전례에서 양측성이며 고음장애형이었다. 4) 임피던스 청력검사상 tympanogram A형이 2귀 였으며 2례(4귀)에서는 acoustic reflex가 나타나지 않았다. 5) 청력손실을 보인 7례중 3례에서 75% 이상의 SISI score를 나타내었고 어음청력검사상 25㏈ 이상의 청력손실을 보인 예는 없었다. 6) 전해질농도와 난청의 정도, 혈액투석회수와 청력손실의 정도에는 유의한 연관이 없었다.

• The Korean Journal of Rheology
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• v.7 no.2
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• pp.150-157
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• 1995

본 논문의 목적은 협착이 발생괸 원관과 분기관내 혈액과 혈액대용유체의 유동문제 에 수치해석방법을 적용하여 유동특성을 파악하는데 있다. 혈액대용유체로서는 Separan AP-273 500wppm 수용액과 Carpobol 934 1.0w% 수용액을 사용하였다. Carbopol 수용액의 유변학적 성질은 수정멱법칙모델, 그리고 혈액과 Separan 수용액의 유변학적 성질은 Carreau 모델로 나타내었다. 협착관유동에서 Carbopol 수용액의 재부착거리는 혈액이나 Separan 수용액의 경우보다 길고 협착으로 인한 압력강하는 Carbopol 수용액, 혈액, Separan 수용액의 순으로 작게 나타난다. 분기관유동에서 Separan 수용액의 압력손실은 혈 액과 Carbopol 수용액보다 작게 나탄나고 협착이 발생괸 부기관내에서 혈액과 Separan 수 용액의 압력손실은 협착이 없는 분기관의 압력손실보다 크게 증가한다.

• Journal of Power System Engineering
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• v.11 no.2
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• pp.38-43
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• 2007

전자기적으로 지지되는 임펠러를 가진 원심 혈액 펌프는 기존의 심장 펌프에 비해 많은 장점을 가지고 있지만, BVAD의 틈새에서 발생하는 유체 동역학적인 문제는 여전히 규명이 되지 않은 상태이다. 본 연구에서는 BVAD의 틈새에서 발생하는 혈액외상(blood trauma)의 예측에 대한 연구에 중점을 두고 있다. 일반적으로 원심 혈액 펌프의 설계를 위해 전자기적으로 지지되는 원심 혈액 펌프의 디스크 틈새에서 발생하는 혈액의 손상을 평가하는 방법으로 CFD를 이용한 방법이 널리 이용되고 있다. 따라서, 본 연구에서는 초기 원심 혈액 펌프의 설계 단계에서 펌프의 특성을 평가하기 위하여, 축 방향 틈새의 영향과 회전수 변화에 따른 누수경로의 전단 응력의 크기 평가를 CFD를 사용하여 해석하여 보았다.

• Korean Journal of Poultry Science
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• v.37 no.2
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• pp.173-180
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• 2010

This study was conducted to investigate the effects of dietary supplementation of mulberry leaves and dandelion extracts on performance, proximate composition, heating loss, drip loss, and blood characteristics of chickens. One hundred sixty broiler chicks were fed diets for five weeks containing 1% mulberry leaves extracts (T1), 2% mulberry leaves extracts (T2), 1% dandelion extracts (T3), and 2% dandelion extracts (T4). At the end of five week feeding experiment, broiler were slaughtered, and stored at $4^{\circ}C$. T2 resulted in much better weight gain and feed conversion than other treatment groups. As storage time increased, all treatment groups resulted in increased heating loss and drip loss (P<0.05) but no significant difference were observed among the treatment groups. In blood composition, GOT (glutamic oxaloacetate transaminase), GPT (glutamic pyrubic transaminase), total cholesterol, and triglyceride were significantly decreased by the supplementation of mulberry leaves and dandelion extracts compared to the control (P<0.05). Especially, T4 was significantly (P<0.05) more effective in improving blood composition compared to other treatment groups. However, no significant difference (P>0.05) were found in LDL-cholesterol among all treatment groups. In conclusion, these data indicate that compared to other treatments, supplementation of 2% dandelion extracts (T4) were most effective in decreasing total cholesterol and triglyceride and increasing HDL-cholesterol.

• Journal of Biomedical Engineering Research
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• v.24 no.4
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• pp.293-299
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• 2003

In this paper, the correlation of Pressure drop about the Newtonian and non-Newtonian fluid was investigated experimentally for vibrating intravascular lung assist device (VIVLAD) and we determined correlation equation to make a prediction about Pressure drop for designing VIVLAD. Design conditions to predict the pressure drop of the modules were studied through an experimental modeling before inserting the artificial lung assist device into as venous. Experiments were performed by distilled water, glycerol/water mixed solution(40% glycerol) of Newtonian fluids. and the bovine blood of non-Newtonian fluids. These fluids were flowed outside and parallel of hollow fiber membranes. Also we measured pressure drop according to the number of the fiber membranes which ware inserted into the inside diameter of shell of 3 cm, and developed the prediction equations by curve fitting method based on correlation between the experimental pressure drop and the frontal area or the packing density of device. The result showed that the Pressure drop and the friction factor of the water/glycerol mixed solution were similar to that of bovine blood. It was showed that the water/glycerol mixed solution (40% glycerol) could be used for measuring the pressure drop and the friction factor instead of the bovine blood. Also, we could estimate the prediction equation of pressure drop and friction factor as the function of Packing density at the number of hollow fibers. We obtained the reliance of the prediction equations because the pressure drop and the friction factor measured from the experiments were similar to that from the prediction equation. These results may be used to further usefulness for the design of VIVLAD.

• Journal of Preventive Medicine and Public Health
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• v.31 no.2 s.61
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• pp.249-264
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• 1998

Reports on a potential relationship between sensory neural hearing loss(SNHL) and cardiovascular or hematologic factor show that the results are controversial. A detailed analysis of risk factors in the development of SNHL was carried out in 3,050 non-noise exposed healthy worker. The mean hearing threshold of both ears at 500, 1000, 2000, 4000, 8000Hz was measured and the effect of age, possible cardiovascular risk factor and hematologic factor (blood viscosity and hemostatic factors) on SNHL were evaluated. first, each of these were associated with loss of hearing sensitivity when univariately and multivariatively analysed. In a multiple regression model, age, sex, body mass index, WBC and total cholesterol level were independently associated with the mean of hearing sensitivity decrease at 4000 and 8000Hz. Second, study subjects were divided into two group (normal vs SNHL) and we compare the possible risk between both groups, and analysed univariate and multivariative logistic model. In a multiple logistic regression model, age, sex, body mass index, WBC and total cholesterol level, total protein, platelet were independently associated with SNHL. Our results show that we have some reliable indices of susceptibility to SNHL using cardiovascular measures or biochemical factor, but future, more extensive studies are required.

• Journal of Biomedical Engineering Research
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• v.23 no.1
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• pp.27-32
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• 2002

The purpose of this study was to evacuate the effects of the number of tied hollow fibers in a novel membrane oxygenator that satisfied the limiting factor of minimizing the friction loss in the intravascular blood flow Pattern. The membrane oxygenator is a bundle consisted of several hundred ho1low fibers haying the outside diameter of 380 $\mu m$ and the axial jacket length of 600 mm. The eight different variation of tied hollow fibers in a bundle were designed. and the liquid flow pattern was controlled by a pump. The liquid pressure drop was measured by in vitro experiments using water and g1ycero1. Uniform blood flow pattern was observed for each number of tied hollow fibers. Pressure drop was 13-16 mmHg outside of the membrane oxygenator consisting of up to 700 ho1low fibers. More effective contact of liquid with the tied ho1low fibers was observed as a decrease in the number of the tied hollow fibers. and resulted in the enhancement of the friction tractor

• Journal of Power System Engineering
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• v.14 no.5
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• pp.41-47
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• 2010

티타늄과 티타늄 합금은 재료적 특이성 때문에 심장 혈관 임플란트에서 일반적으로 사용되어 왔다. 일찍이 적용된 예로는 인공심장판막, 심박조율기의 보호케이스, 혈액 순환 장치 등이 있다. 하지만 물질유도혈전증(Material-induced thrombosis)은 혈전폐색에 의해 기인한 기능 손실로 심장혈관 임플란트 장치의 주된 합병증으로 존재하고 있으며, 심장혈관 임플란트의 혈전유전자는 심장혈관장치의 발달에 주된 난관 중 하나로 남아있다. 그리고 텍스처 혈액 접합 물질(Textured blood-contacting material)은 1960년대 초반 이후부터 혈액순환 보조 장치의 임상실험에 사용되고 있다. 접합 물질에 내장된 텍스처 섬유조직 표면은 형성, 성장, 안정적 부착, 생물학적 내벽(neointimal layer) 등 유도 혈액(entrapping blood) 성분에 의해 형성된다. 공동(cavity) 형상의 용해 가능한 미립자를 사용하는 SCPL법(Solvent casting/particulate leaching method)은 티타늄 기질 이전에 형성된 폴리우레탄 위에 텍스처(texture)를 생성하기 위해 사용되었다. 또한 콜라겐의 부동화(不動化)에 의한 공동(cavity)은 혈액 접합면에 잔존하기 위한 내피세포를 고정할 수 있는 효과가 있다. cpTi로 층화된 PU 기소공성(microporous)은 구조적 특성과 혈전증 감소를 위한 생물학적 내벽 사용의 잠재성을 평가하기 위한 세포 공동체 실험을 통해서 평가되었다.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.48 no.1
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• pp.102-107
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• 2011

The current blood control system is using barcode and scanning one by one to manage blood bags. To have better management and accuracy, an RFID BIS (blood information system) is implemented with an UHF RFID tag antenna using a reflecter for a blood bag has been used.. The UHF RFID tag for blood bag, attached on the high permittivity blood, is designed and fabricated. The tag antenna is optimized and fabricated with the simulation tests such as the existence and nonexistence of the reflector, various distance between the reflector and the dipole tag, the different widths of the reflector and the existence and nonexistence of the T-matching structure. The characteristics and the reading range patterns of the tag antennas are measured. The BIS is implemented with the new tag design.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.16 no.8 s.99
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• pp.810-814
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• 2005

Input power for TEM cell apparatus due to SAR(Specific Absorption Rate) for culture blood cell is determined by the transmission and reflection measurement of blood into the TEM cell. Blood cell with skin cell are reference culture cells for the study of EM wave effect. Exposure RF power from exposure apparatus to culture cell should not only exact for SAR value, but also should be based on the theoretical theory. In this paper, insertion loss of 50 g blood was measured to know exposure power per gram for culture blood cell, and input power of TEM cell due to SAR 0.8, 1.6, 3, 4 mW/g using the measured data are delivered. This study is for applying to EM wave exposure apparatus to culture cell.