• Tuberculosis and Respiratory Diseases
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• v.47 no.6
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• pp.824-835
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• 1999

Background: Sleep-related breathing disorders are commonly found in patients with chronic renal failure and particularly, sleep apnea may have an influence on the long-term mortality rates in these patients. Maintenance hemodialysis is the mainstay of medical measures for correcting the metabolic derangements of chronic renal failure but it is uncertain whether it may alleviate sleep disorders including sleep apnea. Methods: Forty seven patients on maintenance hemodialysis were surveyed with the sleep questionnaire about their clinical symptoms related to sleep disorders. Among them, 15 patients underwent the polysomnography and their blood levels of urea nitrogen, creatinine, electrolytes and the arterial blood gases in the nights before and following hemodialysis were measured. Results: Forty(85.1%) of the 47 patients complained of the symptoms associated with sleep-wake cycle disturbances, 55.3% experienced snoring and 27.7% reported witnessed apneas. The duration of REM sleep increased significantly in the nights after hemodialysis compared to the nights without hemodialysis(p<0.05) and the percentage of total sleep time comprising NREM sleep decreased significantly in the nights following hemodialysis compared to the nights before hemodialysis(p<0.05). The percentage of total sleep time consisting of the stage 1 and 2 NREM sleep showed the trend for a decrease in the nights after hemodialysis(p=0.051), while the percentage of total sleep time comprising the stage 3 and 4 NREM sleep did not change between nights. The obstructive sleep apnea was more predominant type than the central one in both nights and there were no differences in the apnea index and the apnea-hypopnea index between the nights. The decrease in the blood level of urea nitrogen, creatinine, potassium and phosphorus was observed after hemodialysis(p<0.05), but the differences of parameters measured during polysomnography between the nights did not correlate with the changes of biochemical factors obtained on the two nights. Arterial blood gas analysis showed that pH was significantly greater in the nights after hemodialysis than in the nights before hemodialysis(p<0.05), but there were no correlations between the parameters examined during polysomnography and the parameters of arterial blood gas analysis(p<0.05). Conclusion: These results suggest that chronic renal failure is an important systemic disorder which is strongly associated with sleep disorders. Maintenance hemodialysis, although it is a widely accepted measure to treat chronic renal failure, did not significantly modulate the sleep architecture and the severity of sleep apnea. Thus, taking the patients with chronic renal failure into account, it is advisable to try not only to find a substantial way for correcting metabolic derangements but also to consider the institution of more effective treatments for sleep disorders.

• Journal of Korean Society of Transportation
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• v.26 no.6
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• pp.49-60
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• 2008

The aim of this study was to evaluate the variability of the blood.breath ratio (BBR) value and to rationalize the determination of ethanol in breath for evidential sobriety testing. In the experiment forty eight healthy persons, 24 men and 24 women, took part. The experiment included the experimental condition such as sex(2),the type of alcoholic beverage(2; soju, whisky), the type of food(2;kimchi stew, pork belly) and the amount of ethanol consumed(2; 0.35g/kg, 0.70g/kg, based on body weight ) according to 24 factorial design by orthogonal arrays. Breath and blood sample were taken each 8 times and 5 times after the end of drinking. The blood and breath alcohol measurements were highly correlated (r = 0.973). The Results of four way analyses of variance revealed a significant 'the type of food' effect for maximum BrAC (F (1, 43) =5.1, pp<.029), but no significant effect in the type of alcoholic beverage and sex. The overall blood/breath ratio (${\pm}$ SD) was 2295${\pm}$403 and the 95% confidence interval were 1489 and 3101. In spite of these variations, at this time, it seems to be reasonable that apply 2100:1 conversion factor to breathalyzers, because most of the subjects showed the blood.breath ratio of over 2100:1 at least 30 minutes or more passed from the time of drinking as shown in this study.

• Journal of Digital Convergence
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• v.10 no.11
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• pp.541-550
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• 2012

The purpose of this study was to investigate the effect of aerobic exercise training and half bath on blood component, cardiorespiratory function, and vascular compliance of middle-aged obese men. The subjects were 3 groups; aerobic exercise(n=10), half bath(n=10), and controlled group(n=10). They were tested on their blood component, cardiorespiratory function, and vascular compliance at the beginning and at the end of the 12-week study(pre-post test). For data analysis, mean and standard deviation scores were calculated, and repeated measure two-way ANOVA and Scheffe were used. The results of this study are as follows. First, aerobic exercise group was significantly improved on all blood component after the 12-weeks, and showed significant difference among groups. Half bath group was better than control groups on Triglyceride, LDL-C, and HDL-C levels. Second, aerobic exercise group was significantly improved on maximum oxygen uptake, maximum heart rate, and maximum ventilation after the 12-weeks. Third, in vascular compliance measured in both hands and both feet, the half bath group and aerobic exercise training group were significantly increases the control group. Therefore, these results imply that aerobic exercise and half bath can be helpful for better blood component, cardiorespiratory function, and vascular compliance in middle-aged obese men.

• KOREAN POULTRY JOURNAL
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• v.14 s.150
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• pp.27-34
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• 1982

최근 일부지역에서 발병된 바 있는 전염성 후두기관염은 호흡곤란을 주특징으로 하는 닭의 급성 호흡기병이다. 피가 섞인 가래가 기관안에 가득차 있기 때문에 골골거리며 호흡이 대단히 답답하고 곤란하여 목을 길게 위로 빼고 입을 벌리고 괴성음을 내며 호흡을 하기도 한다. 기관의 점막이 붓고 염증이 생기며 점막이 탈락되면서 출혈하기도 하고 각혈을 하면서 응고된 혈액이 기관을 메꾸어 호흡이 곤란하게 되어 질식하여 죽는다. 이러한 증상은 동물이기에 그대로 보아 넘기기 쉬우나 숨통이 피와 가래로 메꾸어져 호흡을 하지 못하고 질식사하는 장면은 차마 보기 어려운 비참한 죽음의 질병이다. 이병은 과거에 발생이 없어 다행으로 여겨 왔으나 이제 부터는 이 전염병에 대한 예방대책을 강구하지 않으면 안되겠다.

• The Journal of the Korea Contents Association
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• v.12 no.4
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• pp.292-303
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• 2012

This study was performed to examine the effects of Dan Jeon Breathing on depression, anxiety and fatigue of hemodialysis patients. This study used the nonequivalent control group pretest-posttest design. Before applying the Dan Jeon Breathing program, the patients were divided into the experimental group and the control group, respectively, and were requested to report their self-ratings to measure their depression, anxiety and fatigue. The Dan Jeon Breathing program was given to both groups for 60 minutes a day and 2 times a week for 12 weeks. The data collected from the program were analysed by means of ${\chi}^2$ test, Fisher's exact probability test, Shapiro-Wilk, t-test and Mann-Whitney U test. The analyses revealed that the depression (t=-2.459, ${\rho}$=.019) and anxiety (t=-2.541, ${\rho}$=.016) levels of the experimental group decreased after Dan Jeon Breathing compared to those of the control group. The difference in fatigue level was statistically insignificant (Z=-1.871, ${\rho}$=.061), though. From the above results, it was verified that Dan Jeon Breathing could be used as nursing intervention for hemodialysis patients to mitigate their depression and anxiety.

• Clinical and Experimental Pediatrics
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• v.45 no.8
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• pp.1000-1006
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• 2002

Purpose : In the course of treatment, patients with hematological or oncological disorders often develop pulmonary complication. The patients who develop a severe pulmonary complication have a poor outlook. The causes of pulmonary complication are either infectious or non-infectious in origin. We have analyzed the etiology and outcome of these patients admitted to the pediatric intensive care unit of Asan Medical Center. Methods : Medical records of 95 patients on Pediatric oncology service who were admitted to pediatric intensive care unit(PICU) of Asan Medical Center from Jan 1997 to May 2000 were retrospectively reviewed. Results : The mean age of the patients was 8.5 years(2 months-18 years). The underlying malignancies of these 95 patients were as following; acute lymphoblastic leukemia(31 cases), lymphoma (11 cases), acute myeloid leukemia(nine cases), brain tumor(eight cases) and other solid tumors(25 cases). Pulmonary complications included pneumonia, acute respiratory failure, pneumothorax and pleural effusion. The most common cause of pulmonary complication was infection(88%) in etiology. The overall mortality rate was 56.8%. Pulmonary complications in these patients carried high rates of mortality regardless of whether they were immune compromised(76%) or not(69%). Even without pulmonary complications, the hematological or oncological patients admitted to PICU had high mortality rates of 43%. Conclusion : Pulmonary complications are frequent finding in the hematological or oncological patients admitted to Intensive Care Unit. The main etiology of these pulmonary complications was infection, which carried a high mortality rate regardless of their immune status at the time when they were admitted to PICU.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.12
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• pp.5882-5892
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• 2012

This study was performed to examine the effects of Dan Jeon Breathing on stress, sleep disturbance and self-esteem of hemodialysis patients. This study used the nonequivalent control group pretest-posttest design. Before applying the Dan Jeon Breathing program, the patients were divided into the experimental group and the control group, respectively, and were requested to report their self-ratings to measure their stress, sleep disturbance and self-esteem. The Dan Jeon Breathing program was given to experimental groups for 60 minutes a day and 2 times a week for 12 weeks. The data collected from the program were analyzed by means of ${\chi}^2$ test, Fisher's exact probability test, Shapiro-Wilk and t-test. The analyses revealed that the stress(t=-2.95, p=.006) and sleep disturbance(t=-2.13, p=.041) levels of the experimental group decreased after Dan Jeon Breathing compared to those of the control group. The difference in self-esteem(t=2.44, p=.020) level was statistically significant. From the above results, it was verified that Dan Jeon Breathing could be used as nursing intervention for hemodialysis patients to mitigate their stress, sleep disturbance and to improve their self-esteem.

• The Korean Journal of Physiology
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• v.12 no.1_2
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• pp.35-40
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• 1978

To evaluate orthostatic brain hypoxia from the passive tilt, anesthetized dogs were tilted from supine to $90^{\circ}C$ upright and $90^{\circ}C$ head down position. Blood pH, $Pco_2$ and $Po_2$ changes during tilt were measured on 8 dogs. Respiratory rate was decreased in upright position and increased in head down position comparing to that in rte horizontal position. pH in arterial blood was increased in upright position and decreased in venous blood comparing to that in the horizontal position. No significant changes were found in the head down position. $Pco_2$ of arterial and venous blood was decreased both in upright and head down. position A significant decrease was found in the head down position. $Po_2$ in arterial blood was increased both in the upright and head down position. However, it was decreased in the venous blood. The cause of increased $Po_2$ in arterial blood seemed to do due to hyperventilation and the cause of decreased $Po_2$ in venous blood was thought to be due to increased $O_2$ consumption of animals during the tilt.

• Journal of Life Science
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• v.9 no.2
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• pp.201-206
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• 1999

Nitric oxide(NO) is a potent and selective pulmonary artery vasodilator. Erythropoietin(EPO) is produced in the kidney in response to reduced oxygen availability. In this study, blood samples were collected for determination of NO and EPO concentrations in 18 normal newborns and 16 newborns with respiratory distress syndrome(RDS). Serum was measured by Ding's method for NO concentration and by enzyme-linked immunosorbant assay for EPO concentration. Nitric ion concentration in serum was 14.9$\pm$3.2 $\mu$M in normal control group and 12.8$\pm$3.3 $\mu$M in RDS group. EPO concentration in serum was 16.2$\pm$3.4 mU/ml in normal control group and 21.2$\pm$5.4 mU/ml in RDS group. These results show the decrease of NO and increase of EPO in RDS newborn patients in comparison with normal newborns. Such imbalances may contribute to the development of several clinical symptoms.

• Journal of fish pathology
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• v.34 no.2
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• pp.213-224
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• 2021

Experiments were performed to investigate changes in metabolic rate (MO₂), critical oxygen saturation (S_crit) and hematological parameters of black rockfish, Sebastes schlegeli exposed to hypoxia at 15, 20 and 25℃. The MO₂ was measured at an interval of 10 min using intermittent-flow respirometry. The normoxic standard metabolic rate (SMR) was 116.5±5.5, 188.6±4.2 and 237.4±6.8 mg O₂/kg/hr, and S_crit was 22.1±1.2, 30.6±1.5 and 41.9±1.4% air saturation at 15, 20 and 25℃, respectively. Q₁₀ values were 2.62 between 15 and 20℃, 1.58 between 20 and 25℃, and 2.04 over the full temperature range. In the investigation of blood (hematocrit and hemoglobin) and biochemical parameters (plasma cortisol, glucose, electrolyte and osmolality), the rockfish were subjected to S_crit for each temperature during 4 hr. All of hematological parameters of the rockfish exposed to hypoxic water were significantly higher than those of normoxic control. Moreover, blood and biochemical parameters of the rockfish maintained to normoxic water showed the tendency of increase with temperature, and were significantly higher at 25C. As a result of this experiment, it was found that physiological stress due to hypoxia increased at high temperature.