• Journal of Chest Surgery
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• v.31 no.10
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• pp.973-981
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• 1998

Background: About 30% to 40% of the patients with pathologic stage I non-small cell lung cancer (NSCLC) die within 5 years after complete resection. The identification of poor prognostic factors and the application of additional treatment are very important to improve the survival rate in resected stage I NSCLC. Materials and methods: Sixty-eight(68) patients who had been diagnosed postoperatively between Janury 1989 and December 1995 as having stage I non-small cell lung cancer according to the TNM classification were studied. The postoperative 5-year survival rate was calculated with the Kaplan-Meier method, and clinico- histopathologic factors including age, sex, operative method, type of tumor cell, T factor, grade of the differentiation in a squamous cell carcinoma, invasion of blood vessel and expression of the nm23-H1 protein were investigated and analyzed. Results: The median survival of the entire group of patients was 58$\pm$3 months, with a 5-year survival of 58.9%. In univariate analysis, invasion of blood vessel and poor differentiation of the tumor cell in a squamous cell carcinoma significantly worsened the survival. In multivariate analysis, invasion of blood vessel and grade of the differentiation of the tumor cells in a squamous cell carcinoma remained independent prognostic factors. High expression of the nm23-H1 protein was related to a high postoperative 5-year survival in comparision with low expression of the nm23-H1 pretein (73.0% vs 50.7%), but there was no statistical significance. Conclusions: These results highlight the negative prognostic value of poor differentiation of tumor cells in a squamous cell carcinoma and invasion of blood vessel in stage I non-small cell lung cancer. Also, further studies are necessary to be determined prognostic value of the T factor and expression of the nm23 protein in non-small cell lung cancer.

• Journal of the KSME
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• v.47 no.6 s.319
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• pp.56-60
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• 2007

• Proceedings of the KTCVS Conference
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• 1998.10a
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• pp.176-176
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• 1998

• The Journal of Korean Orthopaedic Ultrasound Society
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• v.3 no.2
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• pp.69-73
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• 2010

Osteochondroma arising around the knee joint may sometimes be associated with vascular complication. Angiography is widely used to demonstrate the vascular complication, but it is invasive. Recently MR angiography is recommended as a non-invasive alternative, but it is very costly. We report a twenty-year-old man with popliteal arterial compression caused by osteochondroma who was diagnosed and assessed the surgical result by Doppler ultrasonography. And we also provide the usefulness of Doppler ultrasonography.

• Journal of Gastric Cancer
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• v.5 no.3 s.19
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• pp.206-212
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• 2005

Purpose: Angiogenesis has a critical role in tumor proliferation, invasion, and metastasis. In gastric cancer, tumor-associated macrophages and mast cells produce angiogenic factors such as VEGF, that inhibit the functional maturation of dendritic cells. The aim of this study is to identify tumor-associated macrophages, mast cells, dendritic cell infiltrations, and microvessel densities (MVD) to investigate the relationship between them and the prognosis for gastric-cancer patients. Materials and Methods: The subjects were 79 patients selected from those who had undergone a curative gastric resection for stomach cancer. With them, Immune-histochemical staining was done using CD34 for the MVD, CD68 antigen for macrophages, and S-100 protein for dendritic cells, and toluidine blue staining was done for mast cells. Results: Macrophage infiltration showed a statistically significant positive correlation with histologic differentiation and a negative correlation with invasion depth, nodal metastasis, and stage. S-100 (+) dendritic cells and mast cells had no significant correlations with histologic differentiation, invasion depth, nodal metastasis, distant metastasis, stage, and MVD. As survival, no statistically significant differences were seen between the variables. Conclusion: Tumor-associated macrophages should be evaluated as possible prognostic markers in gastric-cancer patients.

• 전기의세계
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• v.34 no.9
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• pp.537-540
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• 1985

인체에 발생하는 여러 질환을 진단 및 치료하고 예후를 결정하는데 혈관의 분포 및 그 상태를 관찰하는 것은 극히 중요하다. 형관조영술의 진단적 기치 및 그 임상적 응용은 1950년대 부터 널리 인정되고 있다. 다만 조영제 주입에는 동맥의 천자 및 도관(Catheter)삽입이라는 비교적 침습적 방법에 의존하여 왔다. 최근 Computer의 도입으로 대표되는 전자기술의 발전 등으로 혈관 특히 동맥의 저농도 조영상을 전산처리로서 숫자화하여 증강, 가산 또는 감산시키는 기법이 개발되어 1970년대 후반에 이르러 임상적으로 응용되게 되었다. 이러한 전산화 감산 형과조영술(Digital Subtraction Angiography : DAS)은 종래의 혈관조영술의 기본 수기에 전산 시스템을 복합시킨 것으로 그 임상적 효과는 매우 큰 것이다.

• Journal of Chest Surgery
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• v.39 no.2 s.259
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• pp.171-175
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• 2006

Minimally invasive thoracic surgery has been one of the most important surgical advances recently. Congenital cystic adenomatoid malformation of the lung is a relatively rare anomaly and is clearly associated with various congenital anomalies such as pectus excavatum, cardiac and pulmonary vascular lesions. We have experienced a case that was treated with minimal invasive methods for congenital cystic adenomatoid malformation involving in the right lower lobe and pectus excavatum in a 5-year-old boy. We simultaneously performed thoracoscopic right lower lobectomy and Nuss procedure of pectus excavatum using a substernal steel bar. Therefore, a minimally invasive surgical treatment for this diseases is feasible and cosmetically excellent.

• Journal of Chest Surgery
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• v.37 no.12
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• pp.1022-1024
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• 2004

Pulmonary aspergillosis is the most common disease of fungal infection and has lower infectivity. Pulmonary asergillosis is classified by aspergilloma, bronchopulmonary aspergillosis, necrotic and invasive aspergillosis. Invasive aspergillosis is found in immune compromised host, immunosuppressive treatment after organ transplantation, anticancerous chemotherapy, blood abnormality, AIDS patients etc. We reported a case of invasive aspergillosis in an immunocompetent host, with review of literatures.

• Journal of Chest Surgery
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• v.34 no.5
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• pp.399-402
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• 2001

최근 심폐기를 사용하지 않는 최소침습성 직접 관상동맥우회술(MIDCAB procedure)은 심장수술 분야에서 급속도로 발전을 거듭하고 있다. 금번 저자들은 전에 만들어 준 좌전하행지 이식편이 막혀 관상동맥 재수술을 필요로 하였으나 좌내 유동맥의 혈류량의 불충분하였다고 생각되었다. 1례에서 최소 침습 수기를 통한 액와-관상동맥 우회술을 시행하여 만족스러운 결과를 얻었기에 문헌고찰과 함께 보고하고자 한다.

• Journal of Chest Surgery
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• v.36 no.2
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• pp.98-100
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• 2003

Recently, Minimally invasive direct coronary artery bypass surgery (MIDCAB) is becoming one of the rapidly developing strategies in cardiac surgery. We report a case of MIDCAB used in upper sternotomy because of severe pleural adhesion.