• Korean Architects
• /
• s.592
• /
• pp.86-87
• /
• 2018

• The Science & Technology
• /
• v.27 no.5 s.300
• /
• pp.86-87
• /
• 1994

• Journal of Korean Electronics
• /
• v.18 no.6
• /
• pp.57-58
• /
• 1998

• Investigative Magnetic Resonance Imaging
• /
• v.15 no.2
• /
• pp.102-109
• /
• 2011

Purpose : To retrospectively evaluate the usefulness of diffusion-weighted images, ADC maps and conventional MR images for determination of brain tumor consistency. Materials and Methods : Twenty-three patients with brain tumor underwent MR examinations with T1, T2 and diffusion-weighted images. Regions of interest (ROIs) were drawn in the tumors, and the measured signal intensities (SI) were normalized with the contralateral side. We evaluated the correlation between SI ratios from various images and tumor consistency assessed at surgery. In three patients with both cystic and solid components, each component was evaluated independently. Qualitatively observed SIs were also correlated with tumor consistency. Results : Statistical analysis revealed significant correlation between tumor consistency and ADC ratio (r = -0.586, p = 0.002), SI ratios on T2-weighted images (r = -0.497, p = 0.010), and observed SIs on T2-weighted images (r = -0.461, p = 0.018). The relative ratio of ADC value correlated with tumor consistency most strongly. Conclusion : The measured ratio of ADC, SI ratio and observed SI grade on T2-weighted images can provide valuable information about the consistency of brain tumor.

• Progress in Medical Physics
• /
• v.21 no.1
• /
• pp.52-59
• /
• 2010

To examine among patients with vertebral compression fracture the extent to which signal-to-noise ratio (SNR) and Apparent Diffusion Coefficient (ADC) values at the lumbar vertebral compression fracture site vary on diffusion-weighted MR images according to varying b values on the 1.5T MR device. Diffusion-weighted MR images of 30 patients with compression fracture due to chronic osteoporosis who underwent vertebral MRI from Jan. 2008 to Nov. 2009 were respectively obtained using a 1.5-T MR scanner with the b values increased from 400, 600, 800, 1,000 to $1,200\;s/mm^2$. For diffusion-weighted MR images with different b values, the signal-to-noise ratio (SNR) was assessed at three sites: the site of compression fracture of the lumbar vertebral body at L1 to L5, and both the upper and lower discs of the said fracture site, while for ADC map images with different b values, the SNR and ADC were respectively assessed at those three sites. As a quantitative analysis, diffusion-weighted MR images and ADC map images with b value of $400\;s/mm^2$ (the base b values) were respectively compared with the corresponding images with each different b value. As far as qualitative analysis is concerned, for both diffusion-weighted MR and ADC map images with b value of $400\;s/mm^2$, the extent to which signal intensity values obtained at the site of compression fracture of the lumbar vertebral body at L1 to L5 vary according to the increasing b values were examined. The quantitative analysis found that for both diffusion-weighted MR and ADC map images, as the b values increased, the SNR were relatively lowered at all the three sites, compared to the base b value. Also, it was found that as the b values increased, ADC valueswere relatively lowered at all the three sites on ADC map images. On the other hand, the qualitative analysis found that as the b values increased to more than $400\;s/mm^2$, the signal intensity gradually decreased at all the sites, while at the levels of more than $1,000\;s/mm^2$, severe image noises appeared at all of the three sites. In addition, higher signal intensity was found at the site of compression fracture of the lumbar vertebral body than at the discs. Findings showed that with the b value being increased, both the signal-to-noise ratio (SNR) and Apparent Diffusion Coefficient (ADC) values gradually decreased at all the sites of the lumbar vertebral compression fracture and both the upper and lower discs of the fracture site, suggesting that there is a possibility of a wider range of applications to assessment of various vertebral pathologies by utilizing multi b values in the diffusion-weighted MRI examination.

• Journal of radiological science and technology
• /
• v.34 no.3
• /
• pp.239-244
• /
• 2011

In this study, we evaluated diffusion weighted imaging (DWI) to investigate whether the DWI parameters can predict characteristic parameters on pathologic specimens of tumor or not. CFPAC-1 was injected subcutaneously on the back flank of athymic nude mice (n=13) then two tumors were initiated on each mouse (2${\times}$13=26 tumors). The mice were sacrificed to make specimen immediately after initial MR imaging then were compared with the MR image. A dedicated high-field (7T) small-animal MR scanner was used for image acquisitions. A T1 and T2 weighted axial image using RARE technique was acquired to measure the T2 values and tumor size. DWI MR was performed for calculating ADC values. To evaluate tumor cellularity and determine the levels of MVD, tumor cells were excised and processed for H-E staining and immunostaining using CD31. T2 values and ADC values were computed and analyzed for each half of the tumors and compared to the correlated specimens slide. Median ADC within each half of mass was compared to the cellularity and MVD in the correlated area of pathologic slide. The mean of ADC value is $0.7327{\times}10^{-3}$ $mm^2/s$ and standard deviation is $0.1075{\times}10^{-3}$ $mm^2/s$. There is a linear relationship between ADC value and tumor necrosis (R2=0.697, p< 0.001). DW image parameters including the ADC values can be utilized as surrogate markers to assess intratumoral neoangiogenesis and change of the internal structure of tumor cells.

• Journal of Korean Ophthalmic Optics Society
• /
• v.17 no.3
• /
• pp.293-298
• /
• 2012

Purpose: We compared static retinoscopy in eyes opened with cycloplegic refraction depending on the hyperopia for school-aged children. Methods: There were 59 eyes (30 patients) who were divided into 3 groups - the mild hyperopia (+0.25 D ~ +1.00 D), moderate hyperopia (+1.25 D ~ +2.00 D) and high hyperopia (+2.25 D or more). They all had 0.8 visual acuity or more. Autorefraction and retinoscopy were performed prior to cycloplegic refraction, and then copmared with manifest refraction and cycloplegic refraction. Results: Hyperopia measured with static retinoscopy tends to be measured higher than manifest refraction for school-aged children. Changes of spherical power was statistically significant (p < 0.001). Changes of astigmatism was not statistically significant (p > 0.05). Conclusions: The difference between cycloplegic refraction and static retinoscopy was not significant for hyperopic school-aged children. The use of retinoscopy was limited for opticians because of legal constraints. The usage of static retinoscopy in eyes opened for optician should be generalized under the conditions not using the cycloplegic.

• Journal of Life Science
• /
• v.5 no.3
• /
• pp.117-120
• /
• 1995

Human milk was examined for antiangiogenic activities by using the chick embryo chorioallantoic membrane (CAM) assay and endothelial cell growth. The low molecular weight (20 KD>$\sim$ ) fraction of human milk stimulated the angiogenesis and increased the endothelial cell growth. These results suggest that the increase of angiogenesis and endothelial cell growth might be attributed to several growth factors and/or angiogenic factors in low molecular fraction (20 KD>$\sim$) of human milk.

• Journal of the Korean Society of Radiology
• /
• v.81 no.5
• /
• pp.1210-1215
• /
• 2020

Sparganosis is an uncommon human parasitic infection caused by plerocercoid cysts of the genus Spirometra. Sparganosis of the neck is a rare condition, thus making it difficult to diagnose. It is often initially misdiagnosed as a lymphadenopathy or a soft tissue tumor. Herein, we describe a rare case of apparent sparganosis presenting as a palpable mass in the left neck of a 53-year-old female patient. Imaging studies played a key role in the diagnosis. In this case report, we emphasize that sparganosis should be considered in the differential diagnosis of a palpable superficial mass. We also stress the importance of meticulous radiological review in the context of appropriate clinical suspicion.

• Journal of Korean Ophthalmic Optics Society
• /
• v.13 no.4
• /
• pp.145-149
• /
• 2008

Purpose: To study the difference between refractive errors obtained from manifest refraction (MR) and cycloplegic refraction (CR) in first-time spectacle wearers. To study the difference between manifest refractive errors and cycloplegic refractive errors in first-time spectacle wearers. Methods: From January 2002 to December 2002, manifest and cycloplegic refractions were carried out on the patients who visited an ophthalmology clinic for a spectacle prescription for the first-time. The patients were 509 male and 499 female patients aged between from 3 to 15 years old. Results: The cycloplegic refraction showed a less myopia and a more hyperopia compared with the non-cycloplegic refraction. The differences were more in female patients. The CR showed a less myopic and a more hyperopic refractive errors than the MR. The differences were more in female patients. The average results from a pre- and a post-cycloplegic refraction showed a reduction of -0.22D in male, and -0.20D in female for the myopic group. For the myopic group, the myopic refractive errors by MR were -0.22D in male and -0.20D in female higher than the refractive errors by CR. Hyperopic group showed an increase of +0.37D in male, and +0.56D in female. For hyperopic group the hypropic refractive errors by CR were +0.37D in male and +0.56D in female higher than the refractive errors by CR. This difference between the results of a preand a post-cycloplegic refraction was more if the patients were younger. This difference between refractive errors by MR and by CR showed the younger the more and the proportions of pseudo-myopia and or latent hyperopia were also higher with younger patents age. The amounts of with-the-rule astigmatism and the oblique astigmatism were increased for the post-cycloplegic refraction in the CR refraction. Simple astigmatism reduced, but there was no difference found in the amount of astigmatism. The prevalence of simple astigmatism reduced, but there was no difference in the amount of astigmatism. Conclusions: The difference between manifest refraction and cycloplegic refraction was more in younger group. The difference of refrative error between by MR and CR increases with ageing decrease. Pseudo-myopia and latent hyperopia was also found in the younger group. Simple astigmatism reduced after cycloplegic refraction, there was no difference found in the amount of astigmatism. The prevalence of simple astigmatism reduced, but there was no difference in the amount of astigmatism.