• Title/Summary/Keyword: 핵물리

Search Result 149, Processing Time 0.032 seconds

Effects of Electrical Stimulation on the Nucleolar Organizer Region in Keratinocyte of Wounded Skin in Rat (전기자극이 흰쥐 창상 표피세포의 핵소체형성부위에 미치는 영향)

  • Lee Jae-Hyoung;Jekal Seung-Joo;Park Seung-Teack
    • The Journal of Korean Physical Therapy
    • /
    • v.12 no.1
    • /
    • pp.1-7
    • /
    • 2000
  • The purpose of this study was to determine the effect of microamperage electrical stimulation on the number of argyrophilic nucleolar organizer region (AgNOR) in rat skin. Twenty four male Sprague-Dawley rats were divided into electrical stimulation and control group. Bach animals hair on the back was removed. The electrical stimulation group received an positive rectangular positive electrical stimulation with $500{\mu}A$, while the control group was given the same treatment without electricity. The rats were sacrificed at 4 and 7 day of stimulation, respectively. The biopsy specimens were fixed in formalin, embedded in paraffin and stained with silver nitrate. The AgNOR were counted using a light microscope and computerized image analysis system and calculated as the mean number of AgNOR per nucleus in the epidermal keratinocyte. In control skin, the mean AgNOR count of epidermal keratinocyte at 4 and 7 day were 1.67 and 1.72, whereas electrical stimulated rat had mean AgNOR counts of 2.0 and 2.14, respectively. A Student's t-test showed a significantly higher mean AgNOR number at 4 ana 7 day in the electrical stimulated rats than control rats (p<0.05). The microamperage electric current stimulation increased the epidermal AgMOR expression in incisional wound skin. These results suggest that the microamperage electrical stimulation may promote migration and proliferative activity of epidermal keratinocyte in surgical wound.

  • PDF

Numerical study on the thermal-hydraulic safety of the fuel assembly in the Mast assembly (수치해석을 이용한 마스트집합체 내 핵연료 집합체의 열수력적 안전성 연구)

  • Kim, YoungSoo;Yun, ByongJo;Kim, HuiYung;Jeon, JaeYeong
    • Journal of Energy Engineering
    • /
    • v.24 no.1
    • /
    • pp.149-163
    • /
    • 2015
  • In this study, we conducted study on the confirmation of thermal-hydraulic safety for Mast assembly with Computational Fluid Dynamics(CFD) analysis. Before performing the natural convection analysis for the Mast assembly by using CFD code, we validated the CFD code against two benchmark natural convection data for the evaluation of turbulence models and confirmation of its applicability to the natural convection flow. From the first benchmark test which was performed by Betts et al. in the simple rectangular channel, we selected standard k-omega turbulence model for natural convection. And then, calculation performance of CFD code was also investigated in the sub-channel of rod bundle by comparing with PNL(Pacific Northwest Laboratory) experimental data and prediction results by MATRA and Fluent 12.0 which were performed by Kwon et al.. Finally, we performed main natural convection analysis for fuel assembly inside the Mast assembly by using validated turbulence model. From the calculation, we observed stable natural circulation flow between the mast assembly and pool side and evaluated the thermal-hydraulic safety by calculating the departure from nucleate boiling ratio.

A Comparative Study of Branching Ratio of 167Yb Radioactive Isotope from Gamma-ray Spectrum Produced by 169Tm(p,3n)167Yb Reaction with 100-MeV Proton Beam (100-MeV 양성자 빔을 이용하여 169Tm(p,3n)167Yb 반응에 의해 생성된 167Yb 방사성동위원소에서 방출되는 감마선 스펙트럼 비교 연구)

  • Sam-Yol, Lee
    • Journal of the Korean Society of Radiology
    • /
    • v.16 no.7
    • /
    • pp.953-960
    • /
    • 2022
  • The measurement of branching ratio of 167Yb radioactive isotopes from gamma-ray spectrum of 169Tm(p,3n)167Yb reaction were performed by using a 100-MeV proton linear accelerator of the Korea Multi-purpose Accelerator Complex (KOMAC). The 167Yb isotope has a half-life of 17.5 minutes and decays to 169Tm. The gamma rays generated from the 167Yb isotope were measured using an HPGe detector gamma ray spectroscopy system. The energy calibration of the detector and the efficiency measurement of the detector were determined using a standard source. The gamma rays of known main energy (62.9, 106.2, 113.3, 143.5 and 176.3 keV) were measured. On the other hand, information about the intensity of the generated gamma rays is very inaccurate. Therefore, in this study, the decay strength of the main gamma rays was accurately measured. Overall, it was different from the previously known results, and in particular, it was found that the intensity of the main decay gamma ray, such as the 113.3 and 106.2 keV gamma ray, was overestimated, and it was found that the gamma ray, such as 62.9, 116.7 and 143.5 keV was underestimated. The present results are considered to be important information in the fields of nuclear fusion, astrophysics and nuclear physics in the future.

Physical Dosimetry in Radioactive Iodine Treatment in the Patients with Thyroid Cancer (갑상선암 환자에 대한 방사성옥소 치료시 물리적 선량 측정)

  • Kim, Myung-Seon;Jeong, Nae-In;Lee, Jai-Yong;Kim, Chong-Soon;Kim, Chong-Ho;Lee, Myung-Chul;Koh, Channg-Soon;Kim, Hee-Geun;Kang, Duck-Won;Song, Myung-Jae
    • The Korean Journal of Nuclear Medicine
    • /
    • v.28 no.1
    • /
    • pp.124-132
    • /
    • 1994
  • Radioactive iodine has been widely used in patients with thyroid cancer combined with surgical treatment. However, due to individual variations in absorption and excretion and uptake by tumor tissue of radioactive iodine, there are differences in therapeutic effect and adverse effects even if the same doses are administrated. So this study compared the therapeutic effect and radiation hazard by measuring internal radiation dose. Of total 27 patients with well differentiated thyroid cancer who had been thyroidectomized, we administered radioactive iodine 100 mCi, 150 mCi, 200 mCi. According to BEL DOSIMETRY PROTO-COL, beta and gamma ray dose were estimated from a pelt of the logarithm of the percent of dose per liter of whole blood versus day, and percent dose retained versus day using somilogarithmic paper, respectively. 1) Physical dose to whole blood averaged $56.54{\pm}13.02$ rad in 100 mCi administered group, $76.83{\pm}19.97$ rad in 150 mCi administered group, $95.08{\pm}25.51$ rad in 200 mCi administered group and there has been a significant correlation among the groups. 2) Mean percent dose retained 48 hours later was 26.34%. 3) There was no significant correlation of physical dose between absence and presence of metastasis. 4) 17 of 19 patients who has been followed up with TSH and serum throglobulin, Thallium scan were successfully ablated by radioactive iodine. 5) Leukocyte, lymphocyte, neutrophil, platelet counts all deelined in 4.6 weeks and most of all were restored 3 months later. 6) There was no significant correlation between physical dosimetry and biologic dosimetry. Generally administered doses of radioactive iodine (100-200 mCi) to patients with thyroid cancer postoperatively had developed transient bone marrow suppression and minimal chromosomal aberration, but they were within safety dose to blood (200 rad). And there has been no significant differences in residual dose 48 hours later between Korean and western people.

  • PDF

Alternative Conceptions of High School Students about the Crust and Interior of the Earth (지각과 지구 내부에 대한 고등학생들의 대안 개념)

  • Jeong, Ku-Song;Jeong, Jin-Woo
    • Journal of the Korean earth science society
    • /
    • v.28 no.3
    • /
    • pp.266-276
    • /
    • 2007
  • This purpose of this study was to analyze high school students' alternative conceptions and understanding levels about rocks, crust, plate tectonics and interior of the Earth. Data were collected through surveys, drawing assignments, and interviews. A total of 158 high school students in the first grade were involved in this study. The results showed that students have lots of major alternative conceptions which are meaning and forming process of rock, distinction of continental crust and ocean crust, formation and disappearance of ocean crust, movement of plate, continental drift, activities of volcano and earthquake. Physical and chemical characteristics, including mantle and core state could be found through analyzing from drawings.

Case Study on Application of Geophysical Survey in the Weathered Slope including Core Stones (핵석을 포함하는 풍화사면에서의 지구물리탐사 적용사례 연구)

  • Hong, Won-Pyo;Kim, Jae-Hong;Ro, Byung-Don;Jeong, Gyo-Cheol
    • The Journal of Engineering Geology
    • /
    • v.19 no.1
    • /
    • pp.89-98
    • /
    • 2009
  • Existence of core stone at the inside of the Rock mass is reacting as unstable element. In particular, in case of the cut slope, even when it is not exposed, slope's discontinuity increases or strength level decreases depending on the difference in the weathering grade when it comes to the core stone, and reacts as an important element of the slope movement such as slope's rock fall or collapse. As for the slope that is subject to study, incision was completed after 20 years or so, and parts of the slope reinforcement was completed, but frequent rock fall occurs despite small amount of rainfall, and permanent stability measures are urgent. Refractional seismic survey and geological survey results were compared and analyzed, and reliability was improved by complementing the two survey methods, and stereo-graphic projection using DIPS program was conducted to analyze the characteristics of oore stone in the weathered soil slope.

Domestic and International Graduate School Education in the Radiological Science : Status and Analysis (방사선학과 대학원 교육의 국내외 현황 및 분석)

  • Ko, Seong-Jin;Kang, Se-Sik;Kim, Jeong-Hoon;Choi, Seok-Yoon;Kim, Chang-Soo
    • The Journal of the Korea Contents Association
    • /
    • v.10 no.7
    • /
    • pp.305-316
    • /
    • 2010
  • The impotance of Radiological science is greater due to development of Science and technology in Medical and Engineering. people who research specific area thought interdisciplinary approach, convergence is essential to pioneer a new field, receive attention was that interdisciplinary approach was needed. so investigating graduate system of radiological science, advanced country, designed to fit their country, could propose reference. the results show, in the university of offered with Master Degree operated program for Clinical experts(Sonography Specialist, Radiation Theraphy Specialist and Nuclear Medicine Specialist)and offered with Ph.D Degree operated program for Scientist and physicist (Nuclear Scientist, Medical Physicist). Note that by this, advanced graduate school program will enable us to become a reader of academia, play a leading role in the world.

원자간력현미경(AFM)을 활용한 SH-SY5Y Neuroblastoma 세포의 분화 전후 세포막의 Stiffness 변화 연구

  • Gwon, Sang-U;Yang, U-Cheol;Jeon, Gwang-Deok;Lee, Ji-Eun;Lee, Hui-Su;Jeong, Jin-Gwon;Hong, Hyeon-Min;Lee, Jeong-Min;Choe, Pu-Reum;Jang, Ju-Hui;Choe, Yun-Gyeong;Jeon, Song-Hui
    • Proceedings of the Korean Vacuum Society Conference
    • /
    • 2013.02a
    • /
    • pp.599-599
    • /
    • 2013
  • 최근의 원자간력현미경(AFM)은 생체물질을 대상으로 여러 구조적 형상뿐만 아니라 물리적 특성 측정이 가능하여 바이오분야에 다양이 활용되고 있다. 줄기세포의 신경세포로 분화 인지에 대한 연구와 관련하여 본 연구에서는 AFM의 한 기능인 Force-Distance curve 측정법을 활용하여 신경암세포주라 불리는 SH-SY5Y를 대상으로 분화 전과 후의 세포막의 stiffness 변화를 측정하였다. 세포막의 stiffness값은 시료표면과 맞닿은 AFM 탐침에 계속적으로 수직방향의 힘이 가해질 시 AFM 캔티레버의 구부러짐 정도로 측정된다. SH-SY5Y는 RA (retinoic acid) 처리에 의해 분화유도 되었으며, 생물학적 방법인 western blotting법을 통해 분화여부를 확인하였다. 측정영역은 AFM topography 이미지 상에서 roughness가 가장 낮은 분화 전과 후 SH-SY5Y의 핵 주변영역으로 선정하였다. 선정된 영역 내에 여러 부분의 분화 전후 세포막의 stiffness 값을 측정하여 통계화한 결과, 분화 전과 후 세포막의 stiffness 차이를 확인할 수 있었다. 분화 전 SH-SY5Y 세포막의 stiffness는 0.79445 N/m인 반면, 분화 후 SH-SY5Y 세포막의stiffness는 0.60324 N/m로 확인되었다. 이는 분화 전에 비하여 분화 후 SH-SY5Y 세포막의 stiffness가 약 24.07% 감소된 것으로 판단할 수 있다. 본 연구는 생물학적 복잡한 방법이 아닌 간단한 방법으로 세포의 stiffness의 변화 측정을 통한 세포의 분화를 판별할 수 있는 방법을 개발한 것으로 여러 줄기세포의 특정세포로 분화여부 판단에 활용할 수 있을 것으로 사료된다.

  • PDF

Crystal growing of sodium type 13X zeolite by continuous crystallization method (연속결정화 방법에 의한 13X 제올라이트 결정성장)

  • 김익진;이해진;서동남
    • Journal of the Korean Crystal Growth and Crystal Technology
    • /
    • v.12 no.4
    • /
    • pp.190-195
    • /
    • 2002
  • NaX zeolite crystals of a uniform particle size of 50 $\mu$m were grown by continuous crystallization method from seed crystals (10~20 $\mu$m) added into a 0.5~2.0 g mother liquor having a composition $3.5Na_2O : Al_2O_3: 2.1SiO_2: 1000H_2O$. In order to investigate the crystal growing by continuous method, the mother solution was supplied after 7 days, 5 days, 3 days and 1 day, respectively. The seeding resulted in an increase in the fraction of large crystals compared with unseeded batches and successfully led to an uniform NaX zeolite crystal. It was postulated that the seeding in the synthesis mixture leaded out increase of surface area for physical contact reaction and directed growth of seed crystal without the nucleation in the synthesis gel.

Discovery of Sub-pc Scale Plasma Torus in the Nearby Radio Galaxy 3C 84 with the KVN and VERA Array (KaVA)

  • Wajima, Kiyoaki;Kino, Motoki;Kawakatu, Nozomu
    • The Bulletin of The Korean Astronomical Society
    • /
    • v.41 no.2
    • /
    • pp.32.4-33
    • /
    • 2016
  • 활동성은하핵(AGN)의 거대 블랙홀 주변에 존재하는 플라스마 디스크의 구조나 물리적인 상태를 관측으로 직접 찾는 것은 AGN 중심부분에서의 제트 형성, 방출과정이나 에너지 수송과정을 조사하기 위해 중요한다. 지금껏 주로 센치미터파장 영역의 다주파 VLBI 관측으로 우리은하에서 가까운 AGN 속에 존재하는 10 pc 정도의 플라스마 디스크가 발견되어 있다만, AGN의 활동성을 정하고 있는 1 pc 이하의 스케일에서의 디스크 구조를 직접 관측한 결과는 아직 없다. 우리는 2015년8월부터 KVN 및 KVN과 일본 VERA로 구성되는 한일공동 VLBI 관측망(KaVA)을 이용해서 전파 은하 3C 84(z = 0.0176, 1 mas = 0.36 pc)의 밀리미터파장 모니터링을 진행하고 있다. KVN과 KaVA를 이용하면 1 pc 이하의 스케일로 3C 84의 중심구조를 고감도에서 분해할 수 있다. 이번 발표에서는 KVN 및 KaVA로 거의 동시에 실시한 관측결과를 중심으로 보고한다. 관측은 2016년2월22일(KaVA 43 GHz) 및 23일(KVN 86 GHz)에 실시되었다. 양 주파수의 이미지에서 종래의 센치미터 ~ 밀리미터파장 VLBI관측으로도 검출되어 있는 중심핵(C1) 및 남쪽에 약 3 mas 떨어져서 위치하는 로브(C3) 성분 뿐만 아니라 C1으로부터 북쪽에 약 2.5 mas 떨어져서 위치하는 새로운 성분(N1)을 검출하였다. N1의 검출 수준은 43, 86 GHz 모두 $6{\sigma}$이며, 양 주파수 사이에서 광학적으로 두꺼운 스펙트럼을 가지고 있다. 과거의 관측으로 측정된 C3의 겉보기 속도는 빛의 속도의 약 23%이며, 남북 로브의 구조와 운동의 대칭을 가정하면 N1이 도플러 분사출 효과 때문에 어두워지고 있는 가능성은 낮다. 따라서 C3에 대응하는 북쪽 N1로브로부터의 복사가 블랙홀 주변의 플라스마 디스크로 인해 저주파수에서 강한 흡수를 받고 있는 결과고 생각된다.

  • PDF