• Food Industry And Nutrition
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• v.19 no.2
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• pp.24-27
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• 2014

• 한국약용작물학회:학술대회논문집
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• 2011.09a
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• pp.260-261
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• 2011

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.10a
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• pp.293-293
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• 2017

• Proceedings of the Korean Nutrition Society Conference
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• 2003.05a
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• pp.275.1-275.1
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• 2003

• Proceedings of the Korean Nutrition Society Conference
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• 2004.05a
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• pp.178-178
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• 2004

• 한국약용작물학회:학술대회논문집
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• 2010.10a
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• pp.292-293
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• 2010

• 한국약용작물학회:학술대회논문집
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• 2008.05a
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• pp.215-215
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• 2008

• 한국약용작물학회:학술대회논문집
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• 2008.05a
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• pp.214-214
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• 2008

• Korean Journal of Plant Resources
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• v.23 no.5
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• pp.423-429
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• 2010

In this study, we examined the anti-diabetic activity in vitro by the mixed Korean herb water extracts(JDG) composed of Lycium chinense, Cordyceps militaris, and Acanthopanax senticosus on hepatic glucose-regulating enzyme activities such as glucokinase(GK), acetyl-CoA carboxylase(ACC), and inhibition activity of $\alpha$-glucosidase. The hepatic cytosol fraction of a type II diabetic animal(Goto-Kakizaki rat) was used in GK and ACC activity assays. JDG mixed water extracts significantly increased the hepatic GK and ACC activity. The highest anti-$\alpha$-glucosidase activity was observed in JDG 5 water extract when compared to the acarbose control, inhibitor of $\alpha$-glucosidase. We suggest that Lycium chinense, Cordyceps militaris, and Acanthopanax senticosus mixed water extracts may exert an anti-diabetic activity by enhancing the glucose metabolism and may be used as natural $\alpha$-glucosidase inhibitors in type 2 diabetic conditions.

• Journal of Life Science
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• v.21 no.1
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• pp.62-67
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• 2011

This study was performed to investigate the physiological activities of stings of Gleditsia sinensis extracts. Antioxidant activity was evaluated by measuring total phenolic contents (TPC), comet assay, and 2.2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity (RSA). Anti-diabetic activity was measured by inhibition activities on $\alpha$-glucosidase. Stings of Gleditsia sinensis extracts were prepared by extracting them with methanol and ethanol. The methanolic extracts showed the highest phenol content (1.12 g/100 g gallic acid equivalents). The $\alpha$-glucosidase inhibitory activity of methanol extracts were 17.9% higher, and that of ethanol extracts were 10.3% higher at a concentration of 1 mg/ml. These results indicate that stings of Gleditsia sinensis might be potential candidates as antioxidant and anti-diabetic agents.