• Proceedings of the Korean Society of Fisheries Technology Conference
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• 2001.05a
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• pp.104-105
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• 2001

Fucoidan은 갈조류 세포 내의 골지체에서 합성되어 세포간물질, 세포벽 구성 물질, 엽상체 표면의 삼출액 둥에 존재하는 산성 다당류의 일종으로 혈액 중에 존재하는 heparin과 그 구조가 비슷하여 혈액 항응고 작용이 있는 것으로 보고(Mori et al., 1982)되어 있으며, 그 외에도 항암작용(Noda, 1990)등 다양한 생리적 기능이 밝혀지고 있다. 또한 fucoidan은 점성이 낮고 용해성이 우수하여 수용성 식이섬유 소재로서의 이용가능성도 매우 높다. (중략)

• The Journal of Korean Academy of Prosthodontics
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• v.25 no.1
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• pp.281-302
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• 1987

의치상 재료 종류에 따라 의치, 점막 및 하악골에 발생되는 변위 및 응력을 연구하기 위하여 컴퓨터를 이용한 수치적 해석인 2차원 유한 요소법을 이용하였다. 2차원 유한 요소 모형으로선 표준 크기의 하악골 및 의치를 고려하여 231개의 사변형 요소 및 268개의 절점으로 분할한 후 각 구성 성분의 물리적 성질인 탄성률 및 프와송비를 대입시켰다. 사용된 의치로서는 일반 합성수지의치, 2mm후경의 탄성재를 의치상 하부에 이장한 합성수지의치, 2mm후경의 탄성재를 치아와 의치상 중앙에 삽입한 합성수지의치 및 0.5mm후경의 금속상의치의 4종류였으며, 하중시에 하악의 고정 부위로선 생체와 동일 조건을 부여하기 위하여 교근, 내측익돌근, 측두근등의 하악 폐구근이 부착되는 하악각 부위 및 하악 근돌기 부위의 16절점을 고정점으로 하였다. 하중 조건으로선 하악 제1대구치의 일점에 10kg의 수직 집중하중, 하악 중절치의 일점에 7kg의 수직 집중하중 및 하악 제 1소구치로 부터 하악 제2대구치까지의 교합면에 10kg의 수직 분산하중을 부여하여 분석한 결과는 다음과 같다. 1. 하중이 의치 교합면위의 가해진 부위에 따라 다양한 의치 회전 및 강하 현상을 보였으며, 탄성재를 이장 및 삽입한 합성 수지 의치의 변위가 일반 합성수지의치 및 금속상 의치의 변위보다 더 컸다. 2. 주응력을 고려할때 점막 부위에는 주로 압축 응력이 작용하였으며 치조제 부위는 압축응력과 인장 응력이 함께 작용하였다. 3. 탄성재를 삽입한 합성수지의치에 최고 등가 응력이 집중되었으며 그 다음은 탄성재를 이장한 합성수지의치, 일반 합성수지의치의 순이였으며 금속상의 경우는 금속을 따라서 높은 등가 응력이 넓게 분산되었다. 4. 의치상 종류에 관계없이 동일 하중 조건하에선 점막에 나타나는 등가 응력의 크기 및 분산양태는 유사하였다. 5. 하악골에서 등가 응력은 의치지지 부위에만 국한되지 않고 넓게 분산 되었으며 의치상 종류 및 하중 조건에 관계없이 치조제 후방 및 하악연의 후방 부위에 특히 높은 등가응력이 집중되었다. 6. 하악 중절치의 일점에 수직 하중을 가한 경우가 다른 하중 조건에 비하여 지지점과의 거리차이로 인하여 하악골에 가장 높은 등가 응력을 유발하였다. 7. 의치상 재료에 따른 하악 골에 발생되는 응력의 크기 및 분산에는 큰 차이가 없으나 금속상의 경우가 교합압을 분산하는데는 효과적이었다.

• Journal of Life Science
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• v.14 no.1
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• pp.91-97
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• 2004

As a part of our study on the improvement of anticonvulsant, here we report the synthesis of N-acyl-$\alpha$-aminosuc-cinimides 1 and N-acyl-$\alpha$-aminoglutarimides 2. (R)-Benzoic acid 4-benzyloxycarbonylamino-2-oxo-pyrrolidin-1-ylester 6a, (R)-4-nifro-benzoic acid 4-benzyloxycarbonylamino-2- oxo-pyrrolidin-1-yl ester 6b, (R) -4-nitro-benzoic acid 4-benzyloxycarbonylamino-2-oxo-pyrrolidin-1-yl ester 6c, and (R)-propionic acid 4-benzyloxycarbonylamino-2-oxo-pyrrolidin-1-yl ester 6d were synthesized from (R)-2-benzyloxy carbonylamino-succinic acid 3 as a starting meterial. (R)-(3- Benzyloxycarbonylamino-2,6-dioxo-piperidin-1-yloxy)-acetic acid methyl ester 10a, (R)-(3-benzyloxycarbonylamino-2,6-dioxo-piperidin-1-yloxy)-acetic acid ethy1 ester 10b, an d (R)-2-(3-benzyloxycarbonylamino-2,6- diox o-piperidin-1-yl oxy)-propionic acid methyl ester l0c were synthesized from (R)- 3-carbobenzyloxy-amino-glutarmic acid 7 as a starting meterial. The yield, mp, IR, $^1H-NMR,\; and^{13}C$- NMR spectra of the products 6a, 6b, 6c, 6d, 10a, l0b, l0c are summarized in footnote. The biological studies of these compounds are in progress and will be reported in future.

• Journal of Korean Society of Steel Construction
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• v.24 no.2
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• pp.233-243
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• 2012

This study verifies the structural capacity of the composite PHC pile (Pretensioned spun high-strength concrete) consisting of a PHC pile and two CT structural steels. Four full-scale specimens are fabricated and the experimental tests were performed to investigate the flexural behaviors of the composite PHC piles. The composite PHC pile can enhance both the structural capacity and functional convenience, since the web of CT structural steel with holes in the web acts as a shear connector (referred to as the perfobond rib), which can connect concrete and steel. All specimens exhibited flexural failure and the ultimate strengths were larger than the anticipated design strength according to the design standard. Thus, the composite PHC pile can be applicable to wall structures with sufficient strength. In addition, it seems that the web of the CT structural steel with holes performs its role as shear connectors.

• Journal of Korean Society of Steel Construction
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• v.19 no.3
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• pp.247-258
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• 2007

This paper describes the results of an experimental study on the new type of encased composite beams that use deep deck plates, which could reduce the story height of buildings by controlling the bottom flange of steel beams. The profiled steel beam was thus developed. It was advantageous to the long span of the buildings. Seven full-scale specimens were constructed, and simply supported bending tests were conducted on the encased composite beams with different steel plate thicknesses, with and without shear studs, reinforcing bars, and web openings. The test results showed that the encased composite beams that were developed in this study had sufficient composite action without additional shear connectors due to their inherent shear-bond effects between the steel beams and concrete.

• The Korean Journal of Zoology
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• v.31 no.3
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• pp.157-164
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• 1988

SCK tumor cells were exposed to heat shock or several sulihydryl-reacting agents such as iodoacetamide(IAA), zinc chloride(Zn), and 2-mercaptoethanol(ME). Stress proteins induced by these agents were examined and the relationship between the induction of stress proteins and the production of abnormal proteins was discussed. Based on the present experiments, two classes of intracellular pathways for the induction of stress proteins were defined; one dependent on and the other independent of protein synthesis. The presence of cycloheximide during the induction period blocked the formation of stress proteins in the cells exposed to Zn or ME, but not in those exposed to heat shock or IAA.Therefore, stress protein seems to be induced either by denaturation of pre-existing mature proteins (e.g., heat shock or IAA) or by newly synthesized abnormal proteins(e.g., Zn or ME). In conclusion, it is ilkely that the production of abnormal proteins by stresses triggers stress protein induction. In addition, it was found that the cells exposed to IISP and GRP inducers simultaneously responded to more strong stress among several stresses encountered.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.29 no.5A
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• pp.433-445
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• 2009

The panels are used as a composite part of the completed deck. They replace the main bottom transverse deck reinforcement and also serve as a form surface for the cast-in-place concrete upper layer that contains the top of deck reinforcement. Research has also demonstrated that mechanical shear ties on the top of the panels are required. In a composite deck with precast panels, it is required to notice behavior of transverse joints between panels. In this paper, static tests of composite deck with shear ties and loop joints were conducted. From the results, the validity of loop joints for continuity of deck was observed. Also, a composite behavior was abserved between precast panel and slab concrete. Tested composite decks with shear ties have 140~164% ultimate strength than have no shear ties due to the increase of composite action. Therefore, the shear ties between the slabs were sufficient to enforce composite flexural behavior to failure.

• Journal of Korean Society of Steel Construction
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• v.18 no.4
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• pp.405-416
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• 2006

In composite girders with steel embedded in concrete as preflex beams, horseshoe connectors and bar connectors are commonly used to achieve composite action. Considering the requirements on the concrete cover in the thin concrete part surrounding a steel member, it has limitations with respect to the use of stud shear connectors, and significant bond and friction resistance can be generated. High horizontal shear strength between the casing concrete and the steel section is needed to introduce prestress to the concrete section in the form of preflex beams.In this paper, experiments on the evaluation of the static strength of horseshoe connectors and bar connectors were conducted and the effects of bonds were also considered. Based on the test results, current design codes were estimated and more general design guidelines that consider the design concept of Eurocode were proposed for the connectors. A strength evaluation according to failure and compared with the test results.

• The Korean Journal of Malacology
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• v.32 no.1
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• pp.17-23
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• 2016

Ultrastructural studies of oocyte development and vitellogenesis associated with the follicle cells in female Phacosoma japonicus were investigated by electron microscope observations. Vitelloogenesis in the oocytes occured by way of endogenous autosynthesis and exogenous heterosynthesis: vitellogenesis occurred through a process of endogenous autosynthesis, which involves a combined activity of the Golgi complex, rough endoplasmic reticulum, and mitochondria. However, the process of exogenous heterosynthesis involved endocytotic incorporation of extraovarian precursors into the basal region of the early vitellogenic oocytes. In this study, follicle cells, which attached to the previtellogenic and vitellogenic oocytes, were easily found. In particular, the follicle cells were involved in the development of previtellogenic oocytes by the supply of nutrients, and vitellogenesis in the early and late vitellogenic oocytes by endocytosis of yolk precursors. The functions of follicle cells, which attached to mature oocytes, accumulate reserves of lipid granules and glycogen particles for vitellogesis in the cytoplasm of the follicle cells.

• Proceedings of the Korean Society of Fisheries Technology Conference
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• 2000.05a
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• pp.74-75
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• 2000

핵산의 생합성은 salvage합성이 우선되며 이 경우 섭취된 음식물유래의 핵산등이 이용되므로 섭취되는 핵산의 영양학적 가치는 매우 높다(송영정사, 1995). Van Buren이나 Kulkarni등은 mouse에의 핵산 경구투여가 면역능을 개선하여 세균감염에 대한 방어에 유효하다고 보고하였고(Van Buren C.T et al, 1983, Kulkarni A.D et a 1986), 이들의 연구가 계기가 되어 섭취 핵산의 유용성에 대한 연구보고가 계속적으로 행하여지고 있는데 그 생리활성을 살펴보면 세포부활작용(Matsunaga et al, 1987) 면역증강작용(Frederic B. Rudolph, 1994) 과산화지질 형성억제작용(Uauy R et al 1985), 장내균총 및 지질대사의 개선작용(Uauy R, 1994, Angel Gil et al, 1986)등이다 본 연구에서는 부산물로 폐기되어지는 참치정소를 이용하여 핵산복합물질을 분리·정제하는 방법 및 그 추출물의 생리활성을 연구하므로써 새로운 기능성 소재로서의 이용가능성을 탐색하였다. (중략)