• Korean Journal of Acupuncture
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• v.40 no.1
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• pp.25-31
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• 2023

Strabismus is a vision disorder in which the eyes do not properly align with each other when looking at an object and it can negatively affect the quality of life. This case is a report on a strabismus patient who received Korean medicine treatment including scalp acupuncture. Scalp acupuncture, body acupuncture, and herbal medicine were performed on a patient diagnosed with strabismus and diplopia. The improvement of symptoms was evaluated by the Numeric Rating Scale (NRS), Scott and Kraft Score (SK score), and change of symptoms and progress of diplopia. NRS decreased by more than 85%, and the SK score gradually changed from -4 to 0, which means strabismus mostly recovered, and the symptom and progress of diplopia were reduced. In this study, it is considered that Korean medical treatment including scalp acupuncture is useful for strabismus patients.

• The Journal of Korean Medicine
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• v.44 no.1
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• pp.38-55
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• 2023

Objectives: The purpose of this study was to provide direction for future research in the field of Korean medicine by analyzing microbiome based technologies emerging as a new diagnostic and treatment paradigm. Methods: To achieve the purpose of the study intellectual property data was used. After establishing citation network from registered microbiome-related US patents, citation network was analyzed by knowledge persistence-based main path approach to understanding technological trajectories. Furthermore, community detection algorithms were used to quantitatively identifying specific technological domain in a particular time period. Results: Results shows that early technologies in livestock industry contribute most to the recent patents. Knowledge in the patents flow through the path of food and beverage technological domain, and finally are inherited to the recent development of diagnosis, treatment and prevention technic. Conclusions: This study indicate that developing diagnostic tools which can link the composition of microbiome to specific diseases should be given high priority. Researches should lead to novel therapeutic strategies. Specifically, improving reliability of pattern identification and finding effective therapeutic compositions based on principles of Korean medicine is necessary.

• The Journal of the Society of Stroke on Korean Medicine
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• v.21 no.1
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• pp.39-46
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• 2020

■ Objectives The purpose of this case report is to show the effect of Traditional Korean Medicine(TKM) on a patient with Cluster Headache. ■ Methods A patient diagnosed as Cluster Headache was treated with herbal medication(Sihogyejitang plus Oryungsan), acupuncture, electro-acupuncture. Then we evaluated the improvement with NRS(Numeral Rating Scale) of headache, number of headache attack and O2 inhalation. ■ Results We could observe decrease NRS of headache and number of headache and O2 inhalation after 10 days of the TKM treatment and there was no reattack after treatment for 43days follow up period. ■ Conclusion This case showed the effect of TKM treatment on Cluster headache.

• The Journal of Internal Korean Medicine
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• v.42 no.6
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• pp.1223-1236
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• 2021

Objectives: The aim of the current study was to investigate the effect of Sosiho-tang on thioacetamide (TAA)-induced liver fibrosis in mice and to elucidate its underlying mechanisms. Methods: The mice were divided into 4 groups: Normal mice (Normal), TAA-induced control mice (Control), TAA-induced and silymarin-treated (50 mg/kg) mice (Silymarin), and TAA-induced and Sosiho-tang treated (200 mg/kg) mice (SSHT). Liver fibrosis was induced via intraperitoneal injection of TAA three times a week for 8 weeks. Silymarin and Sosiho-tang were concomitantly administered for 8 weeks. Serum and liver tissues were then collected and the anti-oxidant and inflammatory protein levels in the liver tissues were evaluated using western blotting. Results: SSHT administration significantly reduced the levels of AST, ALT, ammonia, and MPO in the serum. SSHT also significantly down-regulated liver NADPH oxidase and regulated the Nrf2/Keap1 signaling pathway. SSHT treatment downregulated the liver NF-κB levels and suppressed inflammatory cytokines. SSHT treatment also decreased bile acid-related factors, such as CYP7A1 and NTCP, and fibrosis-related factors, such as α-SMA and Collagen I. Conclusions: Taken together, these data suggest that SSHT administration suppressed the progression of liver fibrosis by activating the Nrf2/Keap1 pathway and inhibiting NF-κB.

• Herbal Formula Science
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• v.29 no.4
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• pp.297-310
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• 2021

Objectives : In traditional herbal medicine, as clinical experience increased, the number of herbal formulas also increased. For example, there are 61,739 herbal formulas in Pujifang, and 96,592 in Dictionary of Traditional Chinese Medicine Prescriptions. In chapter of Clear Heat (CH; 淸熱劑) of textbook, the 38 formulas were presented. For enhancing understanding of herbal formula, a large majority of books explained each individual formula with description or figure about interactions between constituent herbs. But there is no study on the interrelationship of each CH herbal formulas. This study investigated the interrelationship of CH herbal formulas. Methods : The CH herbal formula were analyzed with the ingredients, actions and clinical applications by literature study. Results : To improve cognition the interrelationship of CH herbal formulas, we analyzed the formulas and established the 16 interrelations of herbal formulas. Conclusions : Finally, this study established the interrelation of herbal formula as one figure. This result could contribute to improve cognition on the interrelationship of CH herbal formulas.

• Herbal Formula Science
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• v.29 no.2
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• pp.105-118
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• 2021

Objectives : The process of disease treatment in traditional medicine is defined as differentiating patterns and determining treatment. As an important part of this process, the herbal formulas are specific combinations or configurations of medicinal herbs that serve as tools for treatment. As clinical experience increased, the number of herbal formulas also increased. For example, there are 61,739 herbal formulas in Pujifang, and 96,592 in Dictionary of traditional chinese medicine prescriptions. In chapter of Release the exterior syndrome (RES; 解表劑) of textbook, the 42 formulas were presented. For the understanding on the formula, most of books explained with description or figure about the formulas. But there is no study on the interrelationship of each herbal formulas. This study investigated the interrelationship of RES herbal formulas. Methods : The RES herbal formulas were analyzed with the ingredients, actions and clinical applications by literature study. Results : To improve cognition the interrelationship of RES herbal formulas, we analyzed the formulas and established the 19 interrelations of herbal formulas. Conclusions : Finally, this study established the interrelation of herbal formula as one figure. This result could contribute to improve cognition the interrelationship of RES.

• Herbal Formula Science
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• v.32 no.2
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• pp.129-139
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• 2024

Objective : This study aims to investigate core herbs and formulas in Internal Medicine on the Liver system (IML) to enhance the efficiency of teaching IML, Herbalogy, and Formula Science, as well as to increase the integration of these courses. Methods : The study employed the frequency concept, commonly utilized in previous studies, alongside network analysis. Results : This study identified frequently used herbs, herbs with high centrality, frequently combined herbs, and core formulas. The herb with the highest frequency was 'Angelicae Gigantis Radix', while the herb with the highest centrality was 'Citri Unshius Pericarpium', and the most frequent herb combination was 'Zingiberis Rhizoma - Citri Unshius Pericarpium'. The network analysis results revealed a total of 5 herbal combination communities. Conclusion : In this study, we identified core herbs using traditional frequency analysis methods. Additionally, to complement traditional analysis methods, we discovered core herbal combinations, and fundamental herbal prescriptions through network analysis. The results of this study can be utilized as foundational data to enhance the efficiency of education in Internal Medicine on the Liver system (IML), Herbology, and Formula Science courses, as well as to improve coherence and consistency between foundational and clinical subjects.

• Proceedings of the Korean Society of Computer Information Conference
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• 2013.07a
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• pp.129-131
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• 2013

현대의학의 발전에 힘입어 의료정보의 양과 질적인 측면에서 한의학의 정보화는 매우 빠르게 확장 및 향상 되고 있다. 그러나 서양의학에 비하여 한의학의 의료정보 활용은 상대적으로 적은 게 사실이다. 이에 본 논문에서는 한의학 정보 활용의 활성화를 위해 한의학 관점에서 논의되고 있는 인체의료정보 획득을 위한 인터페이스 구현에 관한 연구이다. 이를 위해 환자의 신체 통증부위 상태정보를 획득할 수 있도록 웹 환경에서 비주얼 인터페이스를 통한 정보 획득 설계 방안에 대해 살펴본다.

• Proceedings of the Korean Information Science Society Conference
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• 2012.06b
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• pp.354-356
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• 2012

'변증'은 전통 한의학에서 사용되어 온 독특한 진단 단위로써, 향후 정보적 관점에서 중요성이 점점 높아지고 있다. 이에 우리는 변증을 기반으로 서양 의학 관련 문헌 정보들로부터 텍스트마이닝을 통해 추출된 유전자들과 중풍을 일으키는 병인으로 알려진 유전자들과의 관련성을 파악하고자 시도하였다. 실험결과를 통해 뇌혈관질환 질병에 관하여 한의학에서의 변증 결과가 서양의학 기술의 결과와 유사한 생물학적 의미를 전달해내고 있음을 확인할 수 있었다. 우리의 연구는 몇 가지 제약에도 불구하고, 향후 한의학의 객관성을 회복함으로써 가치를 높이고, 서양의학 기술과의 접목을 이루기 위한 중요한 시발 연구가 될 것으로 기대된다.

• Proceedings of the Korea Information Processing Society Conference
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• 2009.04a
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• pp.102-105
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• 2009

한의학은 대체의학이나 예방의학으로서의 활용이 가능한 우리나라의 독창적인 의료 체계이지만 세계시장 진출은 고사하고 국내에서의 인지도마저 낮은 실정이다. 이를 위해 한의학의 진단 기술과 IT 기술을 융합하여 한의학의 진단의 객관성을 확립함으로서 한의학의 대중화 및 인지도 상승을 위해 많은 연구가 진행되고 있으나 망진에서 가장 중요한 색윤에 대한 연구가 이루어지지 않고 있는 실정에서 본 논문에서는 색윤을 특정 할 수 있는 방법을 제안하고 이를 실험을 통해 입증하고자 한다.