• 대한한의학방제학회지
• /
• 제31권2호
• /
• pp.81-98
• /
• 2023

Objectives : This study aimed to analyze the trends in research and development projects related to herbal medicine and natural products in the field of traditional Korean medicine (TKM) over the past 20 years. Methods : Research projects were identified using "Korean medicine" as the subject heading in the National Science and Technology Information Service. The included projects investigated Korean medicine, natural products, or were related to the TKM industry. Data pre-processing and network analysis were performed using Python and Networkx package, and the network was visualized using the ForceAtlas2 visualization algorithm. Results : 1. Over the study period, 4,020 projects were conducted with a research budget of KRW 835.2 billion. Seven institutions performed over 100 projects each, accounting for 2.4% of all participating institutions, and the top 10 institutions accounted for 58.9% of total projects. 2. Obesity was the most frequently mentioned disease-related keyword. Chronic or age-related diseases such as diabetes, osteoporosis, dementia, parkinson's disease, cancer, inflammation, and asthma were also frequent research topics. Clinical research, safety, and standardization were also frequently mentioned. 3. Centrality analysis found that obesity was the only disease-related keyword identified, alongside TKM-related keywords. Standardization, safety, and clinical trials were identified as central keywords. Conclusions : The study found that research projects in TKM have focused on standardizing and ensuring the safety of herbal medicine, as well as on chronic and age-related diseases. Clinical studies aimed at verifying the effectiveness of herbal medicine were also frequent. These findings can guide future research and development in herbal medicine.

• 대한한의학회지
• /
• 제44권3호
• /
• pp.189-200
• /
• 2023

Objectives: The purpose of this study is to analyze the current state of quantitative literature evidence for the prescription of 56 herbal medicines covered by health insurance that have been studied in Korea for the past 30 years, to evaluate the reliability of the evidence, and to find out the research direction of herbal medicine prescription in the future. Methods: 56 kinds of herbal medicine prescriptions were searched in domestic literature search databases OASIS, DBpia, and overseas PubMed, classified into chemistry, toxicity, cells, animals, clinical cases, and clinical trial studies, and built into an EBM pyramid structure. Results: When classified according to research contents, there were 61 cases (7.5%) of physicochemical analysis to identify constituent substances, 80 cases (9.8%) of toxicity evaluation, and 672 cases (82.7%) of efficacy evaluation. The efficacy evidence was classified according to the evidence-based medical pyramid structure: 196 cell trials (29.1%), 372 animal trials (55.4%), 89 case and case reporting series (13.3%), 7 comparative case studies (1.1%), and 8 randomized control clinical trials (1.2%). In the pyramid composition, the basis for the validity of 56 kinds of herbal medicines prescribed was 568 cases (84.5%) in cell and animal units, which could not be said to be highly reliable. There was no relationship between the ranking of quantitative literature evidence for herbal medicine prescriptions and the ranking of salary administration. Conclusions: In an era that continues to require scientific evidence for herbal medicine, traditional herbal medicine should secure the basis for safety validity even for the 10th most frequent prescription among 56 herbal medicine prescriptions for consumers. In particular, traditional herbal medicine should increase the quantitative and qualitative level of case reports on related herbal medicine prescriptions, focusing on each clinical society, and move toward comparative case studies and randomized clinical trial so that traditional herbal medicine is positioned as Evidence-based medicine.

• 동의신경정신과학회지
• /
• 제35권3호
• /
• pp.257-267
• /
• 2024

Objectives: Parkinson's disease is a degenerative neurological disorder caused by dopamine neuron damage, leading to various motor and non-motor symptoms, including depression. While several clinical studies on Traditional Korean Medicine (TKM) have addressed this issue, no comprehensive review has been conducted. This study aimed to summarize and analyze TKM treatments for depression associated with Parkinson's disease. Methods: This study reviewed research focused on treatment of Parkinson's-related depression, particularly examining traditional therapies such as acupuncture and herbal medicine. Data on treatment methods were analyzed to compare approaches of control and experimental groups. Specific use of acupuncture points and other TKM treatments was analyzed. Results: Out of 57 studies, 17 involving 649 participants were selected. Various treatment methods were evaluated, primarily using the Unified Parkinson's Disease Rating Scale (UPDRS). Studies predominantly focused on acupuncture targeting specific points (such as LI 4, GB 20, and ST 36) and the use of various herbal medicine combinations. Conclusions: Of the 17 studies, 13 focused on effects of acupuncture, suggesting that acupuncture might play a significant role in alleviating depression associated with Parkinson's disease. Specifically, the use of acupuncture points such as LI 4, GB 20, and ST 36 showed potential therapeutic effects. Additionally, 13 studies demonstrated that TKM could significantly alleviate depression, indicating the potential for an integrative approach combining Eastern and Western therapies. Herbal medicine and Qigong dance therapy also showed promising effects in improving depression.

• 대한한방내과학회지
• /
• 제41권6호
• /
• pp.1245-1254
• /
• 2020

Introduction: The aim of this study was to report the effect of Korean medicine treatments on a stroke patient with acute cerebral infarction. Method: A 63-year-old male with anterior and middle cerebral artery infarction had symptoms of dizziness and disorientation. The patient was treated with Korean medicine therapy, including the herbal medicine "Sunghyuangjunggi-san-gamibang." Treatment progress was assessed using the Korean version of the Modified Barthel Index (K-MBI) and the Korean dizziness handicap inventory (K-DHI). Results: After 14 days of treatment, the K-DHI score decreased from 78 to 7 and the K-MBI score increased from 18 to 24. The patient's main symptoms were improved after the treatment, and no side effects were observed. Conclusion: Korean medicine treatment, including Sunghyuangjunggi-san, might be a recommended therapeutic option for dizziness and disorientation in stroke patients.

• 대한예방한의학회지
• /
• 제26권3호
• /
• pp.41-48
• /
• 2022

Objectives : This study aimed to investigate the adequacy and satisfaction of the school doctor program of Korean medicine (especially sex education) for elementary school students, to examine differences in parents' perception or satisfaction according to the use of Korean Medicine. Methods : The participants were parents of one elementary school that provided sex education as the Seoul school doctor program of Korean medicine. A self-reported online survey was conducted. The questionnaire consisted of parents and children's experience in using Korean medicine, perception of the school doctor program of Korean Medicine, evaluation and satisfaction of school sex education. Results : The survey was conducted on May 14^th, 2022 during the school doctor program of Korean Medicine briefing session. A total of 92 parents participated in the survey, and the 88 respondents analyzed who voluntarily gave consent. Of the experience of Korean Medicine, 71 parents (80.68%) had lifetime, 16 (18.18%) respondents had within the last three months, and 40 (45.45%) said their children had. Parents' experience of using Korean medicine was related to that of their children's, but there was no difference in the satisfaction the school doctor program of Korean Medicine. Conclusions : The survey showed that parents of an elementary school where Korean Medicine doctors carried out school doctor program evaluated that the school doctor program of Korean Medicine had a positive effect on students' health. There was no difference between parents' satisfaction on school doctor program by the use of Korean medicine.

• 한방비만학회지
• /
• 제21권2호
• /
• pp.80-94
• /
• 2021

Objectives: The purpose of this study is to re-evaluate the importance of questions of obesity syndrome differentiation (OSD) questionnaire based on real-world survey and to explore the possibility of simplifying OSD types. Methods: The OSD frequency was identified, and variance threshold feature selection was performed to filter the questions. Filtered questions were clustered by K-means clustering and hierarchical clustering. After principal component analysis (PCA), the distribution patterns of the subjects were identified and the differences in the syndrome distribution were compared. Results: The frequency of OSD in spleen deficiency, phlegm (PH), and blood stasis (BS) was lower than in food retention (FR), liver qi stagnation (LS), and yang deficiency. We excluded 13 questions with low variance, 7 of which were related to BS. Filtered questions were clustered into 3 groups by K-means clustering; Cluster 1 (17 questions) mainly related to PH, BS syndromes; Cluster 2 (11 questions) related to swelling, and indigestion; Cluster 3 (11 questions) related to overeating or emotional symptoms. After PCA, significant different patterns of subjects were observed in the FR, LS, and other obesity syndromes. The questions that mainly affect the FR distribution were digestive symptoms. And emotional symptoms mainly affect the distribution of LS subjects. And other obesity syndrome was partially affected by both digestive and emotional symptoms, and also affected by symptoms related to poor circulation. Conclusions: In-depth data mining analysis identified relatively low importance questions and the potential to simplify OSD types.

• 대한한방부인과학회지
• /
• 제35권4호
• /
• pp.143-160
• /
• 2022

Objectives: This study aimed to lay the foundation for the Korean medicine infertility treatment support program to be implemented in the future by analyzing the results of the Korean medicine infertility treatment support program implemented by Incheon metropolitan city. Methods: 224 patients applied for the Korean medicine infertility treatment support program conducted by Incheon metropolitan city and had three months of herbal medicine treatment and three months of follow-up time. Information on general, demographic, and infertility-related characteristics of patients before treatment was collected. Information on treatment contents performed by Korean medical doctors during treatment, and information on results and satisfaction after treatment was collected. In order to evaluate the safety of treatment, blood tests were performed before and after treatment, and abnormal reactions were monitored. Results: Of 224 patients, 211 ended treatment, of which 45 (21.33%) succeeded in pregnancy. The characteristics of the successful and failure groups of pregnancy were found to be statistically significant differences in age, therapeutic history, parity, anti-müllerian hormone test results, and type of infertility of the patients and spouses. The most common pattern identification was kidney deficiency, and the most widely used prescription was Jogyeongjongok-tang. Patients were highly satisfied with the treatment of Korean medicine infertility. As a result of the safety evaluation, herbal medicine treatment was confirmed to be a safe treatment. Conclusions: In this study, clinical information on the Incheon metropolitan city Korean medicine infertility treatment support program was obtained. Based on this study, it is expected that the Korean medicine infertility treatment program in the future will guarantee more extensive treatments such as extending the treatment period or supporting korean herbal medicine to spouses.

• 대한예방한의학회지
• /
• 제27권1호
• /
• pp.69-87
• /
• 2023

Objectives : This study collected and analyzed information related to preventive formulas from continuously published and revised COVID-19 treatment guidelines in various regions of China. Methods : We collected treatment guidelines published in different regions of China and categorized formulas for prevention and medical observation period listed in them according to the editions. The categorized preventive formulas were compared by type and target group. Results : Herbal medicines used for prevention included formulas derived from Korean medical classics, such as Okbyeongpungsan(玉屏風散) and Eunkyosan(銀翹散). The newly composed formulas, totaling over 100, were created by adding, subtracting, and combining formulas such as Sang-gukeum(桑菊飮), Eunkyosan(銀翹散), Sasammaekmundongtang(沙參麥門冬湯), Okbyeongpungsan(玉屏風散), Gwakhyangjeong-gisan(藿香正氣散), and Soshihotang(小柴胡湯). Patent medicines including Huoxiangzhengqi capsule(藿香正氣膠囊), Lianhuaqingwen capsule(連花淸瘟膠囊), Shufengjiedu capsule(疏風解毒膠囊), and Jinhuaqinggan granule(金花淸感顆粒) were frequently used, mainly targeting close contacts. These medicines were used differently depending on the specific population group, such as the general population, the elderly, children, pregnant women, and patients with underlying diseases, and were also applied differently according to the individual's constitution. Conclusion : We were able to identify various background factors contained in the guidelines for the use of preventive formulas presented by TCM group, and understand the social conditions that enabled the group to provide such guidelines. Through this, thorough preparation should be made so that the Korean Medicine can actively respond to another future pandemic.

• 대한예방한의학회지
• /
• 제26권2호
• /
• pp.55-67
• /
• 2022

Objectives : This study is aimed to survey Korean Medicine Doctors's perceptions in Korean Medicine Clinical Practice Guideline and Standard Korean Medicine Clinical Pathways for its spread(to increase utilization in clinical sites). Methods : The research population was set at 14,831 Korean medical institutions registered with the Health Insurance Review and Assessment Service for sampling representative of Korean Medicine Doctors, and the final 2,007 subjects were selected in consideration of the research period and budget. This survey was conducted based on a telephone survey, and in some cases, a fax or e-mail survey was also conducted together. Six questions were asked about the perception of 'Korean Medicine Clinical Practice Guideline and Standard Korean Medicine Clinical Pathways', and three questions about the characteristics of the respondent. Results : The rate of recognizing Korean Medicine Clinical Practice Guideline was 36.1%. Those who worked at Korean medicine hospitals, were under 39 years of age, and had less than 11-20 years of experience as an Korean medical doctor were more likely to be aware of it. Regarding the experience of using Korean Medicine Clinical Practice Guideline, the rate of 'not used in the past and not used now' was very high at 82.9%, but the intention to use it in the future was high at 60.7%. About the Korean Medicine Clinical Pathways, 79.9% of respondents answered that they did not know. 80.6% of respondents recognized the need for the development of clinical manuals such as Korean Medicine Clinical Practice Guideline and Standard Korean Medicine Clinical Pathways. Conclusion : Their low awareness of Korean Medicine Clinical Practice Guideline seems to affect its low utilization. Therefore, active education and public relations are required in the future.

• 한국지식정보기술학회논문지
• /
• 제12권1호
• /
• pp.69-78
• /
• 2017

KOIN(한의 사람들, http://www.koin.re.kr)은 한의학에 관심 있는 사용자들이 한의 정보를 공유할 수 있도록 구축된 한의 지식 포털이다. 본 연구의 목적은 KOIN을 본격적으로 서비스하기 전에 향후 KOIN 서비스에 대한 사용자 확보를 위해 콘텐츠와 서비스 측면에서 질적 고도화 방안을 모색하는 데 있다. 이를 위해 크라우드 테스팅 기법을 활용하여 현재 KOIN의 기능성 및 사용성 테스트를 수행하였으며, 국내외에서 KOIN과 유사한 사이트를 조사해 비교하였다. 기능성 테스트 결과 약 150여 개의 기능적 문제점이 발견되어 수정하였으며, 사용성 테스트에서는 평균 3.33점이 나왔는데, 이 중 신뢰성 점수가 가장 높았고 유희성 점수가 가장 낮았다. 또한, 국내외 의료분야에서 KOIN과 유사한 15개의 웹사이트들에 대해서 특징 및 장단점을 분석해서 KOIN의 개선 방향을 도출하였다. 특히, KOIN은 다른 포털들에 비해 근거에 기반한 한의 지식을 제공하는 장점을 가진 것으로 분석되었다. 향후에도 사용자의 요구 사항을 지속적으로 수집하여 사용자들이 필요로 하는 한의 지식 서비스를 제공할 수 있도록 할 계획이다.