• 대한화장품학회지
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• 제45권1호
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• pp.37-47
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• 2019

최근 미세먼지, 내분비장애, 환경 호르몬등에 의해 피부 염증 질환 환자들이 증가함에 따라 화장품 소재 개발 연구는 스테로이드, 항히스타민제 등의 피부염 치료 합성화합물 보다 이를 대체할 수 있는 천연물 기반의 보다 안전한 소재 발굴에 관심이 더 증가되고 있다. 따라서 본 연구에서는 여러 가지 천연 약재 스크리닝을 거쳐 피부 효능 효과가 검증된 두충, 익지인, 백강잠의 한방추출물(Mix)을 선정하고, 이들의 새로운 피부효능을 규명하여 천연 화장품 소재를 개발하고자 하였다. 우선 한방추출물(Mix)의 항산화 효능을 검증하기 위해 DPPH assay를 수행한 결과 $400{\mu}g/mL$ 농도 조건에서 약 98.8% DPPH radical 소거 활성을 확인하였다. 한방추출물(Mix)의 미백효능을 확인하기 위해 B16F10 세포주를 활용하여 한방추출물에 의한 멜라닌 합성량을 측정하였다. $400{\mu}g/mL$ 농도 조건에서 ${\alpha}-MSH$ 처리군 대비 27.1% 수준까지 멜라닌 합성량이 감소하여 미백효능 활성에 대해 유의성 있는 결과를 확인하였다. 또한 한방추출물(Mix)의 항염증 효능을 확인하기 위해 LPS 자극으로 활성화된 RAW264.7 대식세포에서 NO(nitric oxide) 합성 및 iNOS, COX-2의 유전자 발현을 관찰한 결과 모두 유의적으로 감소되는 것을 확인하였다. 염증성 사이토카인으로 알려진 $IL-1{\alpha}$, $IL-1{\beta}$, IL-6, $TNF-{\alpha}$의 mRNA 발현을 분석한 결과에서도 한방추출물에 의해 효과적으로 억제되는 것을 확인하였다. 마지막으로 피부장벽 기능 강화를 확인하기 위해 인간 각질형성세포인 HaCaT을 이용해 tight junction 구성 단백질인 claudin 1 유전자의 발현 변화를 관찰한 결과 한방추출물에 의해 mRNA 발현이 농도 의존적으로 증가되는 것을 확인하였다. 따라서 본 연구를 통해 우리는 두충, 익지인, 백강잠을 함유한 한방추출물(Mix)이 항산화, 항염, 미백, 그리고 피부장벽 강화 등에 유효한 소재임을 확인하였고, 향후 피부 임상시험 등이 이뤄진다면 피부염 환자에 효과적인 천연 화장품 소재로 개발될 수 있을 것이다.

• 한국의류학회지
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• 제32권2호
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• pp.235-246
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• 2008

The aims of this study were to identify benefits sought for herbal cosmetics and its significance in influencing consumers' attitude and brand choice. A questionnaire was distributed to 900 women between 20 and 50 years old who had purchased herbal cosmetics from Nov. 6, 2006 to Dec. 15, 2006. SPSS 12.0 package was used for data analysis. Factor analysis, $X^2$-test, frequency, percentage, multiple regression analysis were utilized. The results were as follows: 1. The benefits that consumer was seeking from herbal cosmetics could be classified into 9 dimensions; special function, brand, nutritional reinforcement, economy, scarcity, feeling, fragrance, fashion and skin fitness. 2. All of the above benefits sought except economy and fashion had positive impact on consumers' attitude of herbal cosmetics. 3. There was a correlation between types of benefits sought by consumers and their brand selection.

• 발명하는 사람들
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• 36호
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• pp.12-12
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• 2005

연예인 이름에도 상표바람이 분다 - 특허청, 상표 다등록 100대 기업 발표 - 특허정보 조사, 국가 R&D에 반드시 필요해 - 수입화장품, 한방(韓方)으로 `한방` 먹였다 - 전자$\cdot$정보통신분야 상표등록 붐 이루고 있다

• 한방안이비인후피부과학회지
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• 제34권4호
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• pp.12-23
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• 2021

Objectives : This study is to investigate the anti-aging and antioxidant effects of Naesohwangryeon-tang(NSHRT) extract in Hs68 fibroblasts. Methods : The fibroblast cell line Hs68 cells were used and MTT analysis was performed to measure the cell viability of Naesohwangryeon-tang, and then MMP-1 was induced with the cytokine TNF-𝛼 to confirm the anti-aging effect through real-time PCR and ELISA. In addition, ROS was induced with the TNF-𝛼 to confirm the anti-oxidant effect through DCF-DA. The signaling pathway according to the antioxidant effect was performed by western blot. Results : Naesohwangryeon-tang did not show cytotoxicity at all concentrations(100-800㎍/㎖) treated on Hs68 cells, and the inhibitory effect of MMP-1 was also confirmed. In addition, it was confirmed that the intracellular ROS increased by TNF-α was decreased by Naesohwangryeon-tang, and it was confirmed that the expression of NQO1 was increased in a concentration-dependent manner of Naesohwangryeon-tang. Conclusions : These results suggest that Naesohwangryeon-tang can be used as an anti-aging material by demonstrating the anti-aging and antioxidant effects of Naesohwangryeon-tang.

• 대한한방피부미용학회지
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• 제1권1호
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• pp.158-175
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• 2005

The research and development of oriental cosmetics should be the national strategic industry because the oriental cosmetics have competitive power. To activate the industry of oriental cosmetics the support of government is needed. The governments should know the value of oriental cosmetic industry and invest the research and development. The prolonged investment on research and marketing of company and support of government will make the oriental cosmetics progress.

• 식품과학과 산업
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• 제45권2호
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• pp.45-50
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• 2012

• 한국패션뷰티학회지
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• 제5권1호
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• pp.1-7
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• 2007

• 패션비즈니스
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• 제15권1호
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• pp.129-144
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• 2011

The purpose of this study was to investigate the influence of purchasing behavior on brand attitude, shopping satisfaction, and recommendation of herbal cosmetics consumer. Through judgment sampling method, selected 304 survey questionnaires were used for final analysis from herbal cosmetics consumer. With the collected data, t-test, one-way ANOVA, and multiple regression analysis were performed by SPSS 14.0. The results of the analysis were summarized as follows. First, level of education no significant difference on purchasing behavior, but age, marital status, average income, and job type showed significant difference on purchasing behavior. Second, level of education and average income no significant difference on brand attitude, shopping satisfaction, and recommendation, but age, marital status, and job type showed significant difference on brand attitude, shopping satisfaction, and recommendation. Third, the reasonable purchase, conformity purchase, and conspicuous purchase impacts positively(+) influence, but impulse purchase impacts negatively(+) influence on brand attitude. Fourth, the rational purchase and conspicuous purchase impacts positively(+) influence on shopping satisfaction. Fifth, the conformity purchase and conspicuous purchase impacts positively(+) influence on recommendation.

• 한국의상디자인학회지
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• 제14권2호
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• pp.49-62
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• 2012

The purpose of this study was to investigate the relationship between well-being lifestyles and herbal cosmetics benefits sought of female consumers. The data were collected from 301 women living in Seoul, Gyeonggi, Gwangju, Busan, and Gyeongnam province in June, 2011. Statistical methods including frequency, F-test, t-test, Duncan test, factor analysis, Cronbach's ${\alpha}$, correlation coefficient, and multiple regression were used for this study. The results of this study were as follows.: The well-being lifestyles were composed of five factors, 'health pursuit activity', 'eco-friendly product interest', 'eco-friendly dietary', 'eco-friendly clothing', and 'eco-friendly housing'. The herbal cosmetics benefits sought were composed of seven factors, 'special function pursuit', 'skin 'fitness pursuit', 'brand pursuit', 'nutritional reinforcement pursuit', 'economy pursuit', 'fragrance pursuit', and 'scarcity pursuit'. The well-being lifestyles and herbal cosmetics benefits sought according to female consumers's demographic characteristics showed a difference. Female consumers's well-being lifestyles showed that correlation with the herbal cosmetics benefits sought. Female consumers's well-being lifestyles had a influence on their herbal cosmetics benefits sought. The study results are highly expected to be used as valuable sources in marketing strategies for herbal cosmetic industries.

• 대한화장품학회지
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• 제37권2호
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• pp.161-169
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• 2011

본 연구에서는 발모 소재 개발을 위하여 한방복합처방단의 효소처리에 의한 발모 및 흑모 관련 생리활성을 알아보았다. 효소 처리된 한방 복합 처방단의 자유라디칼 소거활성과 superoxide dismutase 유사활성을 알아보았으며, lipoxygenase 활성 저해효과, $5{\alpha}$-reductase 활성 저해효과 및 멜라닌 생성 촉진효과를 확인하였다. 또한, 인체 피부 일차 자극시험 결과 자극이 없는 저자극으로 나타났다. 이로써, 효소 처리된 한방 복합 처방단은 피부자극 없이 모발제품의 기능성 원료로서 큰 가능성을 가지고 있는 것으로 판단된다.