• The Journal of Internal Korean Medicine
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• v.26 no.4
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• pp.881-888
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• 2005

Pontine infarction presents variable neurologic deficits because the pons is a very complicated organ with cranial nerve nuclei and several fiber tracts. A 65 year-old women with dizzness, ataxia and diplopia because of Pontine infarction was admitted at Wonkwang University Jeonju Oriental Medicine Hospital. She was treated with the herbal medicine Joganiknoe-tang(助肝益腦湯) and with acupunture. Improvement in these symptoms was observed, so the specifics of the process in which the patient was treated are here described. Results suggest that Joganiknoe-tang(助肝益腦湯) is an effective treatment for symptoms of pontine infarction.

• The Journal of Internal Korean Medicine
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• v.26 no.4
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• pp.912-917
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• 2005

Caroli's disease is a non-obstructive dilatation of the intrahepatic bile ducts. It is a rare congenital disorder that classically causes saccular ductal dilatation, which usually it segmental dilatation. Caroli's disease is associated with recurrent bacterial cholangitis and stone formation. A 57 years-old female inpatient suffering from cholangitis due to Caroli's disease was admitted at Wonkwang University Jeonju Oriental Medicine Hospital. The patient was treated with herbal medicine such as Yongdamsagan-tang and acupuncture. As result, there was improvement of symptoms. The process and content of treatment and the patient's recovery over general symptoms is described.

• The Journal of Internal Korean Medicine
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• v.17 no.1
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• pp.204-209
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• 1996

Several medicinal Plants in Jeonbuk are screened for the contraction or relaxation to the acetylcholine and histamine induced contraction in the isolated rat and guinea pig's trachea smooth muscle. Contractions evoked by acetylcholine and histamine were inhibited by Flos Farfarae, Poria and Rhizoma alismatis, but contractions were increased Tuber Pinelliae, Herba Chelidonii, Fructus Qusqualis, Radix Asari, Semen Perillae, Folium Artemisiae and Fructus Schizamdrae increased the contractions evoked by acetylcholine and histamine. Radix Puerariae, Radix Osterici Koreani, Rhizoma Zingiberis siccatum, Radix Sanguisorbae, Rhizoma Atractylodis, Fructus gardeniae and Cortex Magnoliae did not effect the contractions evoked by acetylcholine and histamine.

• Journal of Oriental Medical Thermology
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• v.6 no.1
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• pp.69-75
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• 2008

Purpose: We investigated the effect of far-infrared radiating products on cold hypersensitivity of lower limbs using CST. Methods: 7 patients with cold hypersensitivity of lower limbs were investigated in this study. Exclusive criteria was skin diseases, spinal nervous disease and external wounds. They were asked to answer the VAS of cold hypersensitivity at baseline and after 3 weeks. We measured temperature of lower limbs with Spectrum 9000 MB (Dorex Inc, USA). We performed cold stress test (CST) by 3 thermographic observation using DITI : 1st was taken after 15 minutes resting at $25^{\circ}C$, the 2nd was immediately taken after 1 minute soak in $20^{\circ}C$ water, the 3rd was taken at 15 minutes after soak. We performed 3 times of CST : 1st CST was perfomed at baseline, 2nd CST was perfomred after 1 week and just observation, 3rd CST was performed after 1 week using far-infrared radiating products (lasner, UMT, Korea). Results: After using products, temperature of foot incresed more than thigh area, but there was no significance. There was no statistical difference of VAS, change of temperature and CST between before and after using far-infrared radiating products. Conclusion: There was no statistical effect of far-infrared radiating products on change of temperature of lower limbs.

• The Journal of Korean Obstetrics and Gynecology
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• v.23 no.4
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• pp.57-66
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• 2010

Purpose: To provide basic informations for guidelines of Ginseng usage during lactation. Method: Based on a regulation of scope and preparation of herbal prescriptions by Ministry of health and welfare of Korea, we selected the formulae for postpartum care and disease in 7 Korean Medical Classics. And we searched the number of formulae including Ginseng, dosage and indications of Ginseng in formulae in those books. Results: The range of Ginseng dosage during lactation from medical classics is 1.5-18.75g/day for medical purposes. Indications of Ginseng are lethargy, excessive bleeding, asthma, fever, cold, pain, dizziness, mental disorder, spasm, digestive problem, constipation, diarrhea, urinary incontinence, edema, breast engorgement, lack of breastmilk, breast ulcer, etc. But Ginseng had not been used in the case of stroke, epistaxis, beginning of mastitis, tumor of lower abdomen. Conclusions: Ginseng should be recommended less than 1.5g/d as a nutritional supplement. If breastfeeding woman wants to take Ginseng as a medication or as a tonic, she should consult with a official specialist about proper prescription and dosage instead of risky random medication.

• The Journal of Korean Obstetrics and Gynecology
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• v.21 no.1
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• pp.206-215
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• 2008

Purpose: After abortion, many women could have psychologic problems and physical symptoms. But in Korea, the symptoms and psychologic problems and after abortion had rarely been researched. Methods: The subjects were 29 women who visited Kangnam Korean hospital for postabortion management from May 2007 to December 2007. From questionnaire, we researched the variable symptoms after abortion and depression as Edinburgh Postnatal Depression Scale. Results: The 79% of patients took a rest only less than 1 week after abortion. As the rest time was shorter, the number of symptoms was higher. The frequent symptoms were related to the dysfunction of autonomic nerve system and the circulating system. The patients after abortion had high Edinburgh Postnatal Depression Scale scores, the mean score was $13.33{\pm}7.11$. The high EPDS scores and the number of symptoms was related with methods of abortion and age. Conclusions: Postabortal symptoms are related with physical symptoms and depression. So psychological evaluation would be needed. And for prevention of postabortal symptoms, the adequate rest time would be demanded after abortion.

• The Journal of Internal Korean Medicine
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• v.26 no.2
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• pp.409-419
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• 2005

The water extract of Boyanghwanoh-tang has been used for treatment of ischemic vascular disease in oriental medicine. However, little is known about the mechanism by which the water extract of Boyanghwanoh-tang rescues cells from these damages. Therefore, this study was designed to evaluate the protective effects of Boyanghwanoh-tang on zinc-mediated cytotoxicity in H9c2 cardiomyoblast cells. This study demonstrates that, after treatment of H9c2 cells with zinc, there was a decrease in cell viability in a dose dependent manner, and there was a chromatin condensation. Zinc induced the change of cell morphology. In addition, zinc induced mitochondrial dysfunction. Zinc-induced H9c2 cell death was remarkably prevented by the pretreatment of Boyanghwanoh-tang consistently with increase of the peroxoredoxin 1, 2, 3, 5, and 6 expression. Taken together, the results suggest that zinc induced severe cell death in H9c2 cardiomyoblast cells, and that protective effects of Boyanghwanoh-tang against oxidative injuries are achieved through regulation of peroxiredoin expression.

• The Journal of Internal Korean Medicine
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• v.26 no.2
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• pp.420-430
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• 2005

The water extract of Omijatang(OMJT) has been traditionally used for treatment of abscess and heart palpitation in oriental medicine, However, little is known about the mechanism by which the water extract of OMJT rescues cells from these damages. This study was designed to investigate the protective mechanisms of OMJT in H9c2 cardiomyoblasts on oxidative stress-induced cytotoxicity including $H_2O_2,\;ZnCl_2$, hypoxia, and reoxygenation. Oxidative stress markedly decreased the viability of H9c2 cells. This was characterized with apparent apoptotic features such as chromatin condensation as well as fragmentation of genomic DNA and nuclei. However, OMJT significantly reduced $H_2O_2$-induced cell death and apoptotic characteristics as well as $ZnCl_2$, hypoxialreoxygenation. Taken together, this study suggests that the water extract of OMJT has the protective effects against oxidative injuries.

• The Journal of Internal Korean Medicine
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• v.32 no.3
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• pp.444-450
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• 2011

Recently, acute toxic liver injury has been reported to be the most common cause of acute hepatitis. We witnessed one case of hepatic injury which suggested drug-induced hepatitis by herbal medication (Gamiyukgunja-tang). This patient, diagnosed cerebral infarction, was treated with herbal medication and physical therapy for improvement of right hemiparesis. In the course of treatment, this patient showed elevation of serum transaminase (ALT 129 IU/L, AST 150 IU/L), alkaline phosphatase (ALP 261 IU/L), and total bilirubin (2.0 IU/L), so we supposed toxic hepatitis by herbal medication. Saenggangeonbi-tang was administered for 8 days, ALT, AST, ALP, total bilirubin decreased within normal limits.

• The Journal of Internal Korean Medicine
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• v.31 no.3
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• pp.448-456
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• 2010

Objective : To summarize and make a reference number of antihyperlipidemic herbal plants worldwide. Method : We surveyed all papers of antihyperlipidemic studies using herbal plants in Pubmed database as "hyperlipidemia AND herb", "hyperlipidemia AND herbal", etc. of Default Tag "Title". The number of papers, the formation of experiments, frequency of herbal plants studies, and main studies were analyzed. Result : Total 178 studies were finally selected. The number of papers were rapidly was increased since 1998. RCT studies were most papers(39.9%). Most studies were about plant sterol or plant stanol studies(78%). 10 papers studied about Herbal plants. Crataegus pinnatifida Bunge, Salvia miltiorrhiza Bunge, Alisma orientale(Sam.) Juz. and so forth were relatively studied much. Conclusion : This study produced an overview of worldwide antihyperlipidemic plants. This result may provide a valuable information for development of Korean herbal medicine against hyperlipidemia in the future.