• Journal of Digestive Cancer Research
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• v.5 no.2
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• pp.113-119
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• 2017

Background: Second line chemotherapy is often considered in advanced gastric cancers. We assessed irinotecan in combination with fluorouracil in patients experienced diseases progression after first line chemotherapy. Methods: Prospective trial was done at 7 centers in republic of Korea. Patients aged 18 years or older with advanced gastric adenocarcinoma and disease progression on or within 4 months after first-line chemotherapy were assigned to receive irinotecan 180 mg/m² and 5-fluorouraicl 400 mg/m² intravenously bolus injection on days 1 and leucovorin 200 mg/m² for 2 hours and 5-fluorouracil 600 mg/m² for 22 hours intravenously infusion on day 2 of a 14-day cycle (FOLFIRI group). The primary endpoint was objective tumor response (OR). Efficacy analysis was by per-protocol, and safety analysis included all patients who received at least one treatment with study drug. Results: Between January 1, 2014 and December 31, 2016, 28 patients were assigned to FOLFIRI treatment. Of those 20 patients were completed the study protocol. Per-protocol analysis, two patients among 20 subjects (10.0%) showed partial response. Overall survivals of FOLFIRI group; median 10.1 months [95% CI 4.9-15.3] Grade 3 and higher adverse event that occurred about 5%, but grade 3 or higher febrile neutropenia or life threatening complication was not reported. Conclusion: Combination chemotherapy with irinotecan, 5-FU, and LV is feasible in gastric cancer patients previously treated with platinum-based chemotherapy

• The Journal of Korean Academy of Sensory Integration
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• v.21 no.2
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• pp.24-34
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• 2023

Objective : This study sought to investigate the effects of a sensory integration intervention focusing on vestibular and proprioceptive on the spatial relations and visual-motor coordination of children with developmental disorders. Methods : Three children with developmental disabilities aged 5 to 6 years were the subjects of this study, and the ABA' design, which is one of the single subject research designs. A total of 18 sessions were conducted over a six-week period-that is, three 30-minute sessions per week. During the three baseline sessions, the children's spatial relations and visual-motor coordination were evaluated prior to the intervention. During the 12 sessions conducted in the intervention period, a vestibular and proprioception sensory integration intervention was performed, while in the final three sessions, the children's spatial relations and visual-motor coordination were again evaluated (without any further intervention Children were measured and evaluated every session after intervention using a computer cognitive rehabilitation program (CoTras-C). Moreover, the Kaufman Assessment Battery for Children and the Korean-Development Test of Visual Perception-2 were used as evaluation tools to verify the effectiveness of the intervention. Results : There were significant differences in the spatial relations and visual-motor coordination scores of the children with developmental disorders before and after the vestibular and proprioceptive sensory integration intervention. More specifically, after the intervention, all three children showed statistically significant improvements. Conclusion : The applied vestibular and proprioceptive sensory integration therapy had a significant impact on the spatial relations and visual-motor coordination of the three children with developmental disorders.

• Korean Journal of Culture and Social Issue
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• v.16 no.1
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• pp.63-79
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• 2010

The purpose of this study is to investigate the relation among alcohol outcome expectancies, alcohol abstinence self-efficacy, perceived drinking norms and alcohol use. This study was conducted via e-mail. Among 392 students who were participated via E-mail, 300 students (male 148, female 152) were met a definition of Wechsler's binge drinking. The results revealed that perceived norms were associated with alcohol use in binge drinking group, while those were not in non-binge drinking group. It was identified that a difference of peer's actual alcohol consumption and peer's perceived drinking was associated with individual alcohol use. Moreover, for binge drinking group, perceived norms predicted alcohol use better than any other factors. Drinking motives mediated the relation with perceived norms and alcohol use. Especially perceived norms affected alcohol use not only by increasing drinking motives but also by itself. Implication of this study is to provide a basis of prevention and intervention of binge drinking for college students.

• The Journal of the Convergence on Culture Technology
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• v.9 no.6
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• pp.401-407
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• 2023

This study is a descriptive study to identify the patterns of use of menstrual sanitary products among community women of childbearing age. The participants were 1,571 women between the ages of 19 and 40, and data collection was conducted through online and mobile surveys from September 2020 to August 2021. As a result, 88.9% of the participants were using disposable menstrual pad, 5.6% tampons, 3.1% cloth menstrual pad, and followed by others(2.4%), including menstrual cups. The differences of type of menstrual sanitary products according to general characteristics showed significant in age(p=.006), marital status(p=.005), education level(p=.002), annual salary(p=.018), experience of pregnancy(p=.036), and menstrual regularity(p=.022). More than half of the participants(53.8%) responded that cloth menstrual pads were 'very safe' or 'safe,' but 27.9% and 20.1% of disposable menstrual pads and tampons, respectively. The difference in menstrual distress according to the type of menstrual sanitary products showed that tampon users had a higher menstrual discomfort score for the most recent menstruation(F=4.092, p=.017) and 4 days before menstruation(F=4.178, p=.016) than users of disposable menstrual pad or cloth menstrual pad. Therefore, it is necessary to continuously investigate the use of menstrual sanitary products by women of childbearing age and its relationship with reproductive health.

• The Journal of the Korea institute of electronic communication sciences
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• v.18 no.6
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• pp.1217-1228
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• 2023

In this paper, technical and patent analysses of anti-drone technology, which aim to neutralize drone attacks are conducted. We conducted research on the technical definition of anti-drone, the technical elements of anti-drone systems, and investigated the patents related to anti-drone and drone filed domestically and internationally over the past 10 years, starting from 2011. For domestic patents, we examined the number of patent applications related to anti-drone and the overall domestic patent applications over the past 10 years. Regarding international filings, we investigated the patent applications related to anti-drone filed in the United States, Europe, Japan, China, and under the PCT system in the past 10 years. We conducted a search for patents related to anti-drone, including neutralization techniques identified under the keyword "anti-drone," patents related to drone detection and identification techniques, and patents related to drone neutralization techniques. Through the conducted research, a total of 91 patents were filed for drone detection techniques. Out of these, 5 patents, accounting for 5.5%, were filed by public institutions. In the case of patents filed for drone identification techniques, there were a total of 174 patents. Among these, 4 patents, which is 2.3%, were filed by public institutions.

• The Journal of Korean Academy of Sensory Integration
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• v.21 no.3
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• pp.1-12
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• 2023

Objective : The purpose of this study was to compare the effects of the sensory processing characteristics of parents of developmentally delayed children and parents of typically developed children on parenting stress. Methods : From July to August 2022, 61 parents of children with developmental delays and 64 parents of children with typical development who used occupational therapy services at pediatric clinics and child development centers were evaluated for parenting stress and sensory profiles. Results : In a multiple regression analysis on the effect of sensory processing characteristics on the total score of parenting stress, tactile processing (β = 0.353, p = 0.001), gender (β = 0.438, p = 0.000), and monthly income (β = -0.261, p = 0.014) significantly affected the parenting stress of the parents of children with developmental delay. In parents of typically developing children, tactile processing (β = 0.376, p = 0.002) and gender (β = -0.264, p = 0.024) were found to have a significant effect on parenting stress. Conclusion : Parental gender and tactile processing characteristics of developmentally delayed and typically developing children are significant influencing factors for parenting stress.

• The Journal of the Korea institute of electronic communication sciences
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• v.19 no.1
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• pp.267-274
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• 2024

In this paper, we investigated the number of domestic patent applications by year, the number of domestic patent disclosures by year, and the number of domestic registrations by year regarding smart factories. The number of patent applications by applicant type was investigated. Based on the patents studied, it was found that the IPC appearing in the most patents was G05B 19/418. In addition, through social network analysis of smart factory patented IPCs, it was found that G05B 19/418 was the IPC with the highest degree of centrality. From the above, if the IPC of the core technology of the patent submitted for smart factory is G05B 19/418, the technology combined with G05B 23/02, that is, the technology combining "factory control" and "monitoring" is the most patented. When the IPC of the core technology was G06Q 50/04, it was confirmed that the technology combined with G06Q 50/10, that is, the technology combining "manufacturing" and "service" was the most applied for patents. Through this, it was found that in order to apply for a patent for a smart factory, it would be necessary to file a patent application that takes into account the connectivity between IPCs.

• Journal of Korean Dental Hygiene Science
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• v.2 no.1
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• pp.9-17
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• 2019

This study aims to identify the status of oral care of professional soldiers and analyze the relationship between oral care needs and oral health symptoms based on oral health recognition, thus providing an opportunity to create a system for improving oral health of professional soldiers. The study was conducted on a total of 232 military personnel aged 19 or older who were employed in the military. The questionnaire for this study was commissioned to respond by explaining the purpose of the study and how to respond to the survey by telephone with the selected sub-employer. The content included in the questionnaire consisted of general characteristics, oral care status, and awareness of dental hygienists. When the subjective oral health condition was poor, normal, or good, it was all shown that the toothbrush was done more than three times a day, and the oral examination was all examined. In particular, 68.1 percent of the respondents said they were in good subjective health. Preventive treatment was the highest in the group with good subjective oral health. Of the total respondents, 83.6 percent said "yes" to the question of knowing dental hygienists, while 65.5 percent said "yes" to the question of whether they know the work of dental hygienists, recognizing that most of the respondents were aware of dental hygienists and their work. Both the group that said they knew the dental hygienist and the group that said they did not know answered 43.5% as an assistant. In conclusion, oral health projects will have to be carried out in line with military situations in order to maintain a healthy oral state of professional soldiers, and long-term planning for active oral health care, especially as an important role of personnel in charge of health care in the military is needed.

• Journal of Ginseng Culture
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• v.6
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• pp.105-115
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• 2024

Wild ginseng, grown in undisturbed forest environments, has been maintained for centuriesthrough human intervention and knowledge, leading to the development of current ginseng agriculture. The practice of ginseng farming has long been established in various regions of Korea. However, the ginseng farming specifically in Geumsan was recognized as a Globally Important Agricultural Heritage System (GIAHS) by the Food and Agriculture Organization of the United Nations (FAO) in 2018. This designation was granted after a thorough evaluation, which confirmed that Geumsan's ginseng farming met the necessary criteria, including historical importance, traditional knowledge system, agrobiodiversity, and agricultural landscape. Traditional ginseng farming in Geumsan practices the 'rotating agriculture system', a sustainable land use approach that has been developed over several cycles of long duration (10-15 years). It contains the knowledge to choose locations for cultivation that prioritize the direction of sunlight and wind circulation. Furthermore, it received significant recognition for its agricultural heritage value based on its maintenance of several traditional knowledge systems, including ancestral wisdom and knowledge regarding pre-planting field management techniques. As of December 2023, there are currently 86 locations in 26 nations that have been designated as GIAHS. Among these sites, Geumsan stands out as the first and only site in the world specifically recognized for the cultivation of ginseng crops. This historical record serves as a significant reminder of Korea's prominent position as a major producer of ginseng on a global level. This article first provides an overview of the concept of agricultural heritage, the designation criteria, and the status of the designation. It then identifies, among the GIAHS designation criteria, the agricultural heritage value of traditional ginseng farming in the Geumsan region from the perspective of local traditional knowledge systems.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.6 no.1
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• pp.74-89
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• 1995

Selective mutism is a childhood condition defined by persisten failure to speak in specific social situation when speaking is expected, dispite preserved ability to comprehend spoken language and speak. Present study is to investigate clinical characteristics, treatment method and outcome of 23 children who were diagnosed as selective mutism by DSM-IV criteria at the child psychiatry ouptatient department of SNUH. The results were as follows : 1) The Sex ratio was 1: 4.8, female dominant Mear age of onset was 33 years old and mean age of first referral was 7.7 years old. 2) 22% of subjects had perinatal problem such as low birth weight, preterm birth, 26% of the subjects have history of delayed language development. There are subjects who had been separated with mam caretaker before 3 years old(26%) and who experienced physical or psychological trauma before 3 years old(26%). A few subjects had enurests(30%) and encoprests(4%). 3) Many subjects(65%) had symbiotic relationship with their mother. These families consist of dominant, verbally aggressive mother and passive father. Parents of 39% of all subjects were judged to have definite psychopathology(social phobic, depression, hysterical trait or alcohol problem) 26% of all subject, were reported physically abused. 4) The personality trait of the subjects were frequently described as follows(in order of frequency) ; Shy(100%), anxious(83%), stubborn(83%)m rigid and tense posture(78%), immature(65%) overdependent(65%), irritable(52%), manipulative(39%), depressive(39%). 5) The mean performance IQ of 16 subjects by KEDI-WISC was 88.3 Among them, the subjects with IQ below 69 were seven and those with IQ above 70 were nine. When comparing these two group(Mental retardation group vs Normal IQ group), we could find some difference in language development, personality trait, family dynamics and treatment outcome. 6) Among several treatment methods for selective mutism, play therapy was the most frequently used method(65%). Other commonly used treatment methods were pharmacotherapy(21%), behavioral therapy(8%), combined therapy(play therapy+pharmacotherapy+family therapy+behavioral therapy)(12%), 7) Regarding the outcome of treatment 8.6% was evaluated as Excellent, 30.4% as Good, 52% as Fair, 8.7% as Poor at the tinic of treatment. At follow up interview 21.7% was evaluated Excellent, 13% as Good, 21.7% as Fair, 34.8% as Poor. 8) We classified all subjects by Havden's 4 subtype. Symbiotic mutism was most common(65%) and other subtypes are Speech phobic mutism(8.6), Reactive mutism(13%) and Passive-aggressive mutism(30%).