• Proceedings of the Safety Management and Science Conference
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• 2011.04a
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• pp.657-662
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• 2011

어린이 장난감은 과거보다 더 안전성의 필요가 되고 있다. 현대 사회의 가족변화로 인한 구성원으로 인하여 어린이가 귀한 존재가 입장이 되었기 때문이다. 이에 따른 어린이 용구에 대한 관심의 집중도가 높아졌으며 장난감에 대한 인식 변화와 안전성을 추구하고자 하는 노력도 많이 커졌다. 이는 어린이들이 장난감을 가장 많이 신체로 접촉하고 있기 때문이다. 장난감의 특성상 어린이, 특히 유아들이지만 입에 물거나 피부에 문지르고 소리나는 것에 민감하고 장난감의 재질에 따른 향, 촉감 등에 반응할 수 있기 때문이다. 이는 어린이의 처음 부딪히는 감각의 느낌과도 연결되어 감각의 기능에서 발전을 가져올 수 있다고 본다. 어린이들의 연령층에 따라 표현력이 부족하기 때문일 것이므로 어린이 장난감의 안전성에 어른들이 주의해야할 이유라고 여긴다. 즉 어린이 장난감의 안전성을 추구할 수 있는 어린이뿐만 아니라 제2의 소비자인 부모, 친척, 친지, 어린이와 연관된 직종의 어른들일 것이다. 장난감의 시장은 서구보다 발전되지 않았지만 근래에 들어 어린이 장난감은 중국이나 동남아에서 제조되어 한국으로 들어오는 경우가 많다. 따라서 안전성에 대한 인식의 제고와 실질적 노력 추구가 더욱 더 필요하다.

• Proceedings of the KIEE Conference
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• 1996.07b
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• pp.1272-1274
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• 1996

This paper presents the development of tactile sensor systems for robot hand which are truly usable, robust, reliable and cheap system. The sensor incorporates multiple sensing subsystems for detecting distributed contact forces and surface characteristics. The fabrication and experimental evaluation of the tactile system and its electric interfaces are described. The results indicate that the system provides reasonable performances for practical applications requiring manipulation with tactile feedback.

• KSBB Journal
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• v.16 no.3
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• pp.253-258
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• 2001

Recently, there were many studies not only to enhance drug delivery effect but to reduce side effect. Drug delivery system(DDS) is able to improve efficiency with decreasing side effect of drug dosage. Among these application fields, DDS is often used as the method of drug dosage into the epidermic skin. We investigated characters of transdermal therapeutic system(TTS) and the skin permeability of that with applying DDS. We investigated the permeation of xanthan gum containing drug in rat skin using borizontal membrane cell model. Permeation properties of materials were investigated for water-soluble drug with oxiniacic acid and also for lipophilic drug with clofibrate. The permeation rate of lipophilic drug was found to be faster than that of water-soluble drug in vitro. The rate differences of both water-soluble drug and lipophilic drug according to drug content were negligible. We used glycerin, PEG 600 and oleic acid as enhancers. These results showed that skin permeation rate of each drug across the composite was mainly dependent on the property of base and chemical property of drug etc.. Proper selection of the polymeric materials which resemble and enhance properties of the delivering drug was found to be important in controlling the skin permeation rate. This result suggests a possible use of natural polymer base as a transdermal delivery system of antihyperlipoproteinemic agent.

• Journal of Life Science
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• v.21 no.12
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• pp.1761-1771
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• 2011

In the previous results, we developed an effective products to apply as functional foods for overcome of radiation damage and reduction of side effects in radiotherapy. To verify the prevention of UVB-induced immunosuppression of immune cell function by HemoHIM, we studied on the mechanism of the skin immune function for the protection in UVB irradiation. In studies presented here, we showed that HemoHIM can prevent UVB-induced impairment of skin immune cell function by in vitro and in vivo assay. Exposure of freshly cultured murine dendritic cells (DCs) with IL-4/GM-CSF to UVB irradiation resulted in impairment of accessory function. This suppression could be prevented by addition of HemoHIM before or after to the cultures of UVB-irradiated DCs. We also tested the effects of HemoHIM on the suppression of contact hypersensitivity (CHS) treated oral or intraperitoneal administration. This UVB-suppressed CHS was prevented by administration of HemoHIM to UVB-irradiated mice. These results suggest that HemoHIM may prevent UVB-induced immune suppression in the skin.

• Journal of Korean Society of Archives and Records Management
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• v.16 no.2
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• pp.173-183
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• 2016

Fungi are a major cause of cultural and biological degradation in museum storages and archives libraries. In addition, fungi produce toxins and can cause skin allergies. In particular, fungi coming into contact with the skin through the hands of administrators dealing with cultural properties, archives, and books can lead to secondary infections. To prevent this, applying hand sanitizer, which is readily available in the market, is recommended. However, such hand sanitizer can effectively disinfect against bacteria but not fungi. As such, researching for an alternative is required. In this study, we developed a hand sanitizer composed of active ingredients - geranial, cineol, menthol, and Chamaecyparis obtusa - and performed a disinfection test, which targets 10 kinds of species (Alternaria citrimacularis, Alternaria consortialis, Aspergillus niger, Aspergillus versicolor, Cladosporium sphaerospermum, Coniothyrium aleurites, Penicillium brevicompactum, Penicillium corylophilum, Penicillium paneum, and Penicillium polonicum), of fungi investigated in museums and libraries. It was then confirmed to exhibit excellent disinfecting effects. Thus, this hand sanitizer is expected to prevent skin diseases and secondary infections in administrators dealing with cultural properties, archives, and books.

• Journal of the Korean Applied Science and Technology
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• v.36 no.1
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• pp.333-340
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• 2019

This paper was described about the preparation of the multi-functional mask pack and its evaluation. Here, the multi-functional effects means the far-infrared emissivity effect due to polyphosphoric acid, the freckles treatment effect and peeling effects due to inclusion complexes, and the skin temperature decreasing effect due to Lavender-extraction compounds. The the hazardous chemicals, viscosity, and pH were determined blow 0.01%, 280 cP, and pH=6.92 in the prepared multi-functional mask pack solution, respectively. The multi-functional mask pack prepared with dipping method in the solution were showed the value of $0.882{\mu}m$ (Far-infrared emissivity) and $3.40{\times}10^2W/m$ at $37^{\circ}C$ (Far-infrared radiation energy), respectively. After taking multi-functional mask pack, the skin moisturizing rate was indicated 35.5%, and the skin temperature was showed in the range of $24{\sim}26^{\circ}C$. The skin stimulation test for the 30 volunteer was showed very strong stability.

• Analytical Science and Technology
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• v.14 no.5
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• pp.451-457
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• 2001

Because liquids with high molecular weight such as mineral oil have low vapor pressure at room temperature, it is generally thought to be difficult to lose them to evaporation. However, when they are dispersed into air in small droplets during application in machining processes, their surface area becomes considerably higher. To determine the potential for metalworking fluids (MWF) filter losses, MWF mist was generated and collected on polyvinyl chloride (PVC) filters in test chamber. After collected MWF was exposed to clean air during designated period (range 10~240 minutes) and the filters were desiccated, losses were evaluated. As duration of clean air passing through PVC filter increased, loss of MWF gradually increased. MWF lost after 10 minutes ranged form 12.4 % to 21.8 % of the original loading mass, on average 53.3 % of the total loss. These results indicate that significant mass of MWF collected on PVC filters can be lost at the beginning of air sampling. Loss of MWF collected on PVC filter also occurred during desiccation without active airflow. In multiple regression to identify which factors influence the loss of MWF collected on PVC filter, both duration of air passing through PVC filter and MWF age (fresh vs. used) were significant predictor (p=0.0001). Therefore, workers' exposure to MWF measured method 0500, may underestimate true concentration. Further study is needed to develop a new method to quantify the workers' exposure to airborne MWF mist accurately.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.9
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• pp.49-56
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• 2020

High temperature heat generated during rifle firing not only degrades the performance of the weapon, but also limits the user's operation. In this study, temperature change of handguard according to firing was measured with reference to Human Engineering criteria and the operability according to material was examined. Accordingly, for the firing test, three types of Korean rifle and one overseas model were selected for each material of handguard, and firing test was conducted using a contact type temperature meter. The test result shows that using a plastic handguard with low thermal conductivity and aluminum handguard with high thermal conductivity enabled the rifles to be operated with bare hands even when firing at more than 100 rounds at low atmospheric temperature. However, when firing more than 60 rounds at over 20℃ atmospheric temperature, aluminum handguard use is limited. When firing quickly over 100 rounds, handguard use is restricted regardless of its fabrication material. To eliminate operational limitations by overheating, it is necessary to eliminate direct contact with skin using gloves, vertical grips, etc. This study examined the operability of rifles in terms of thermal risk, and the resulting study results are expected to be used as basic data for Human Engineering of other rifles and munitions.

• Journal of Oral Medicine and Pain
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• v.38 no.2
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• pp.109-114
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• 2013

Chemical burn on the oral mucosa is caused by contact with various chemical products and manifests with localized mucositis, keratotic white lesions, bleeding, and painful tissue surface due to the coagulation of the tissue. Policresulen ($Albothyl^{(R)}$) is a topical antiseptic, commonly used over-the-counter drug for vaginitis, thrush and stomatitis. This drug is highly acidic with pH 0.6, and can act as a strong corrosive agent to oral mucosa. When inadvertently used in oral cavity, it may cause chemical burns of oral mucosa, resulting necrosis and bleeding surface resembling to erythema multifome. A 56 years old female patient presented with the chief complaints of painful ulcerations on the tongue, the upper and lower lips. On intraoral examination, an erythromatous, erosive or ulcerative surface covered with inflammatory exudates or bleeding crust is observed on the anterior half of the tongue and the upper and lower lips. She has occasionally applied the policresulen solution topically on the tongue to relieve pain from recurrent focal glossitis for about 10 years. In this time she applied it broadly and repeatedly to the tongue, the upper and lower lips for the purpose of pain relief by herself without instruction by physician or dentist. After cessation of policresulen application, the oral mucosa was rapidly recovered with use of topical steroids. In 2 weeks the lesions subsided completely. In summary, inadvertent use of $Albothyl^{(R)}$ on oral mucosa may result in chemical burn, causing mucosal erosion, ulceration and inflammation. It can be recovered by topical use of corticosteroid for 2 weeks after cessation of using $Albothyl^{(R)}$.

• Polymer(Korea)
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• v.33 no.2
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• pp.111-117
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• 2009

This study aims to verify for humans the suitability of the enzyme-fixed hydrogel used for the patch sensor of the blood sugar testing system without blood sampling, which utilizes reverse iontophoresis. Using acrylate monomers, hydrogel was synthesized to which a certain unit of enzyme is fixed. In order to analyze the material property of the synthesized hydrogel, a structural analysis was performed using FT-IR spectroscopy, while the DSC was used to verify the thermal stability. In addition, with the UV-Vis spectrophotometer, it was verified that the degree of active enzyme is at least 50% greater than the standard product. The SEM was used to verify secure fixation of the enzyme onto the surface. As a result, it was observed that the enzyme is successfully fixed to the surface. Since the hydrogel makes direct contact with a patient's skin, it is essential to evaluate the toxicity when making direct contact with the skin. For that purpose, various sets of tests were undertaken according to the ISO 10993-cytotoxicity, intracutaneous reactivity, skin irritation test and maximization sensitization. Consequently, it was successfully verified that the enzyme-fixed hydrogel have bioavailability.