• The Journal of the Korea Contents Association
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• v.18 no.4
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• pp.99-113
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• 2018

Recently, global warming has widened the habitat of mosquitoes and infection chances for mosquito-borne diseases are increasing. Flavivirus is a typical mosquito-borne virus. Flaviviruses with a relatively high frequency of infection in Asian countries include Zika, Dengue, and Japanese encephalitis viruses. Although distinctive diagnosis of flaviviruses is required because the symptoms and therapeutic method differ, there is no diagnostic method that can distinguish them accurately yet. In this study, we propose distinctive diagnosis method of flaviviruses using informations and analysis tools constructed in bioinformatic databases. The envelope protein and non-structural protein 1 which are useful protein for the immuno-diagnostics of three flaviviruses were selected. Their homology was analyzed by multiple sequence alignments and epitope candidates consisting of 10-15 amino acids were selected. Finally two epitopes were suggested to be most useful by immunogenicity analysis and 3D structure prediction. These approaches and results are expected to be great value in the distinctive diagnosis of three flaviviruses with a high frequency of infection in Asian countries.

• Applied Biological Chemistry
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• v.44 no.2
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• pp.122-128
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• 2001

This review showed a discussion on the biofunctional activities of citrus flavonoids. The major flavonoids of citrus species, hesperidin, hesperetin, naringin, and naringenin, were selected to evaluate their biological effects on the lipid metabolism in rats and hamsters, the proliferation of human hepatocyte HepG2 cells, and the antioxidative effect in lipid peroxidation models. These flavonoids showed hypotriglyceridemic effect in hamsters and hypochloesterolemic effect in rats. They also significantly inhibited the activities of phosphatidate phophohydrolase and acyl-CoA: cholesterol acyltransferase, which are key enzymes for biosynthesis of triglyceride and cholesterol, repectively, in vivo and in vitro experiments. These biofunctional activities by citrus flavonoids were shown more potent in the aglycone flavonoids, hespreretin and naringenin, than their corresponding glycoside flavonoids, hesperidin and naringin. These aglycone flavonoids also have inhibitory effects on proliferation of human hepatocyte cancer HepG2 cells. Hesperidin showed lowering activities of cellular triglyceride and cholesterol concentrations in HepG2 cells. Citrus flavonoids have significant importance in functional food industry as biofunctional active ingredients.

• Journal of the Korean Institute of Intelligent Systems
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• v.26 no.5
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• pp.416-422
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• 2016

Lots of plastics are widely used in a variety of industrial field. And the amount of plastic waste is massively produced. In the study of waste recycling, it is emerged as an important issue to prevent the waste of potentially useful resource materials as well as to reduce ecological damage. So, the recycling of plastic waste has been currently paid attention to from the view point of reuse. Existing automatic sorting system consist of near infrared ray (NIR) sensors to classify the types of plastics. But the classification of black plastics still remains a challenge. Black plastics which contains carbon black are not almost classified by NIR because of the characteristic of the light absorption of black plastics. This study is focused on handling how to identify black plastics instead of NIR. Raman spectroscopy is used to get qualitative as well as quantitative analysis of black plastics. In order to improve the performance of identification, Support Vector Machine(SVM) classifier and Principal Component Analysis(PCA) are exploited to more preferably classify some kinds of the black plastics, and to analyze the characteristic of each data.

• Journal of the Korean Society of Food Science and Nutrition
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• v.41 no.8
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• pp.1100-1105
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• 2012

Green tea intake is known to have preventive effects against cancer. In this study, we evaluated the tumor suppressive effects of dietary green tea extracts (GTE) as a modulator on cisplatin in an established colon cancer mouse model. The cisplatin-induced cytotoxicity was determined with cell viability of the mouse colon cancer cell line (CT26) in vitro. The influence of GTE on the anti-tumor activity of cisplatin was evaluated by measuring tumor size with digital calipers in mice bearing CT26 colon carcinomas. The CT26 cell viability decreased to 93% at a $20{\mu}g/mL$ concentration of cisplatin. However, cell viability decreased to 15% with a combination of $20{\mu}g/mL$ cisplatin and GTE ($75{\mu}g/mL$). There were no apparent changes in cisplatin-induced cytotoxicity with GTE and epigallocathechin gallate (EGCG) treatments. Tumor size decreased in dietary GTE combining intra-peritoneal cisplatin-injected tumors bearing mice compared with cisplatin or GTE alone administered to tumor-bearing mice. These experiments showed that dietary GTE has a potentiating effect on the cisplatin anti-tumor activity of an established mice colon cancer model. Therefore, the GTE may be a candidate for modulators in anticancer treatments with cisplatin.

• Journal of Korean Society of Forest Science
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• v.102 no.2
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• pp.229-238
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• 2013

This study was conducted to analyze on the operational cost of logging operations in the whole-tree logging operation system by tower-yarder and swing-yarder, and in the cut-to-length logging operation system by excavator with grapple in order to spread efficient logging operation technique and to establish the logging operation system. In the results of the analysis of operation cost, in case of the whole-tree logging operation system, the operation cost was 2,099 won/$m^3$ in felling by chain saw, 28,286 won/$m^3$ in yarding by tower-yarder, 18,265 won/$m^3$ in yarding by swing-yarder, 18,939 won/$m^3$ in bucking by excavator with grapple and chain saw, 20,484 won/$m^3$ in forwarding and accumulation by wheel type mini-forwarder, 12,701 won/$m^3$ in forwarding and accumulation by excavator with grapple and small forwarding vehicle. In case of the cut-to-length logging operation system, the operation cost was 10,160 won/$m^3$ in felling and bucking by chain saw, 7,567 won/$m^3$ in cut-to-length extraction by excavator with grapple, 6,982 won/$m^3$ in branches and leaves extraction by excavator with grapple, 3,040 won/$m^3$ in the operation road construction by excavator with grapple, 20,484 won/$m^3$ in forwarding and accumulation by wheel type mini-forwarder, 12,701 won/$m^3$ in forwarding and accumulation by excavator with grapple and small forwarding vehicle.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.11
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• pp.4449-4454
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• 2010

The principal objective of this study was to evaluate the physicochemical characteristics of scattered-flower ladybell powdered brown rice Dasik prepared with four kinds of sugars. We noted that the luminance of control sample was higher than that of BRSM and BRIM, but similar to BRFM sample. In Hunter's a of control were higher than those of BRFM and BRFM, but similar to BRSM sample. In Hunter's of b values were decreased. With regard to the mechanical properties of the Dasik samples, we noted significant differences in hardness, gumminess, chewiness but no differences in springiness and cohesiveness were detected. The hardness, gumminess, chewiness of control sample were lowered than those of BRSM and BRIM. The case of sensory evaluation, there were taste and texture of control sample were higher than those of BRSM and BRIM, but BRFM. And the overall quality of BRFM was significantly higher than those of BRSM and BRIM, but control sample.

• Journal of the Korean Applied Science and Technology
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• v.40 no.5
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• pp.1072-1080
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• 2023

The purpose of this study is to analyze major keywords and social phenomena related to 'plogging' in the sports field and to derive important information. In order to achieve this purpose, the news analysis system BIG Kinds provided by the Korea Press Promotion Foundation was used to analyze it. The analysis period is from 2018 to 2022, and 42 of the 5,148 news collected were finally used and analyzed. Frequency analysis, relationship map analysis, and related word analysis were performed as analysis methods, and the results are as follows. First, as a result of the frequency analysis related to 'Plogging' in the sports field, keywords such as 'Jeju', 'Players', 'World Marathon', 'SSG', and 'Lee Bong-ju' were identified. Second, as a result of the analysis of the relationship related to 'Plogging' in the sports field, keywords such as 'COVID-19', 'national representative', 'elite', 'masters', and 'COVID' were identified. Third, as a result of the analysis of words related to 'Plogging' in the sports field, keywords such as 'synthesized words', 'volunteer activities,' 'masters untact', 'Jeju', and 'athletes' were identified. In the domestic professional sports field, it has been shown that plogging is actively used for environmental activities and professional team promotion to practice carbon neutrality by international sports organizations.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.04a
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• pp.293-293
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• 1994

본 연구에서는 Scutellariae Radix (黃芩)으로부터 분리한 다섯종의 플라보노이드와 그외 구조면에서 관심이 있는 아홉가지 관련 플라보노이드 물질들에 대한 브라디키닌 길항활성물 적출장관 및 여러 in vivo 실험을 통하여 검색하였다. 적출회장 및 자궁실험에 서는 검체들이 거의 모두 BK 길항효과를 나타내었고 특히 적출 자궁실험에서 skullcalflavone 11 와 2'-methoxyflavone이 40 $\mu\textrm{g}$/ml 농도에서 각각 90 및 87%의 억제율을 나타내어 가장 억제적이었다. in vivo 검색에서는 플라보노이드들과 양성대조약물로 사용된 마스피린은 각 실험개시 24시간 및 1시간전에 200 mg/kg의 용량으로 생쥐에게 경구투여하여 BK 길항활성을 비교하였다. 혈장일출, 초산으로 인한 신전반응 및 LPS-유도 septic shock 유발억제 실험에서 특히 2'-methoxyflavone은 신전반응 및 내독소 실험에서 거의 완전하게 억제효과를 나타내었다. 이러한 플라보노이드들은 펩타이드구조를 가진 BK길항제와 비교하여 효력을 낮으나 non-peptide구조로 인해 생리적조건에서 보다 안정한 물질로 연구될 가치가 있다. 본 실험에서는 또한 체내에서 BK와 그 생리작용이 아주 유사한 히스타민에 대한 길항제들중 피페라진핵을 지니고 있는 약물들에 대한 BK 억제효과를 검토해본 결과 homochlorcyclizine이 가장 큰 억제효과를 나타냈으며 이 물질의 해리함수는 6.25 이었고 correlation coefficient는 0.984 로 경쟁적 길항제 이었다. 반면 수용체 결합실험에서는 이 약물은 25%의 수용체결합 억제활성을 나타내었다.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.14 no.7
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• pp.1661-1666
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• 2010

Due to light condition or shadow around camera, acquired image sequence is often degraded by intensity fluctuation. This artifact is called luminance flicker. As the luminance flicker corrupts the performance of motion estimation or object detection, it should be corrected before further processing. In this paper, we analyze the flicker generation model and propose the new algorithm for flicker reduction. The proposed algorithm considers gain and offset parameter separately, and stabilizes the luminance fluctuation based on these parameters. We show the performance of the proposed method by testing on the sequence with artificially added luminance flicker and real sequence with object motion.

• The KIPS Transactions:PartD
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• v.9D no.2
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• pp.277-288
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• 2002

A service broker supporting customers plays an important role in internet marketplaces. Recently. several intelligent brothers have been developed for electronic commerce, outline shopping mall, and electronic marketplaces. While these systems provide interesting shopping experiences, they fall short in fully exploiting the capabilities, such as the service integration and automatic execution required by internet market places. In this respect, we propose a workflow-based service broker system. Dependent services in our approach are modeled as workflow processes, which are automatical1y processed by a workflow engine. In the proposed system all data exchanges are realized through XML providing platform independent, extensible, open. and interoperable architecture.